SARS-CoV-2 Coronavirus Spike Protein-Induced Apoptosis, Inflammatory, and Oxidative Stress Responses in THP-1-Like-Macrophages: Potential Role of Angiotensin-Converting Enzyme Inhibitor (Perindopril)

Severely ill COVID-19 patients display impaired exhaustion features in SARS-CoV-2-reactive CD8+ T cells

(2021) Anthony Kusnadi et al.   Science Immunology

Jaw Periosteum-Derived Mesenchymal Stem Cells Regulate THP-1-Derived Macrophage Polarization

(2021) Fang He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oxidative Stress as Key Player in Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection

(2020) Livan Delgado-Roche et al.   ARCHIVES OF MEDICAL RESEARCH

COVID-19 as a cardiovascular disease: the potential role of chronic endothelial dysfunction

(2020) Jesús F Bermejo-Martin et al.   CARDIOVASCULAR RESEARCH

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

(2020) Carly G.K. Ziegler et al.   CELL

Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

(2020) Vanessa Monteil et al.   CELL

Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients

(2020) Zhuo Zhou et al.   Cell Host & Microbe

COVID-19: A New Virus, but a Familiar Receptor and Cytokine Release Syndrome

(2020) Toshio Hirano et al.   IMMUNITY

Endothelial cell infection and endotheliitis in COVID-19

(2020) Zsuzsanna Varga et al.   LANCET

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

(2020) Mingfeng Liao et al.   NATURE MEDICINE

Zi Shen Huo Luo Formula Enhances the Therapeutic Effects of Angiotensin-Converting Enzyme Inhibitors on Hypertensive Left Ventricular Hypertrophy by Interfering With Aldosterone Breakthrough and Affecting Caveolin-1/Mineralocorticoid Receptor Colocalization and Downstream Extracellular Signal-Regulated Kinase Signaling

(2020) Xiaotong Song et al.   Frontiers in Pharmacology

The pathogenesis and treatment of the `Cytokine Storm' in COVID-19

(2020) Qing Ye et al.   JOURNAL OF INFECTION

The protein expression profile of ACE2 in human tissues

(2020) Feria Hikmet et al.   Molecular Systems Biology

Association of COVID-19 inflammation with activation of the C5a–C5aR1 axis

(2020) Julien Carvelli et al.   NATURE

Incidence of thrombotic complications in critically ill ICU patients with COVID-19

(2020) F.A. Klok et al.   THROMBOSIS RESEARCH

Alveolar macrophage dysfunction and cytokine storm in the pathogenesis of two severe COVID-19 patients

(2020) Chaofu Wang et al.   EBioMedicine

Immunopathology of Hyperinflammation in COVID-19

(2020) Joshua N. Gustine et al.   AMERICAN JOURNAL OF PATHOLOGY

Immunity, endothelial injury and complement-induced coagulopathy in COVID-19

(2020) Luca Perico et al.   Nature Reviews Nephrology

Increased Serum Levels of sCD14 and sCD163 Indicate a Preponderant Role for Monocytes in COVID-19 Immunopathology

(2020) Jose Gómez-Rial et al.   Frontiers in Immunology

Genetic mechanisms of critical illness in Covid-19

(2020) Erola Pairo-Castineira et al.   NATURE

Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19

(2020) Marthe Jøntvedt Jørgensen et al.   Scientific Reports

What Can Cellular Redox, Iron, and Reactive Oxygen Species Suggest About the Mechanisms and Potential Therapy of COVID-19?

(2020) Barry B. Muhoberac   Frontiers in Cellular and Infection Microbiology

Effects of vitamin D on macrophages and myeloid-derived suppressor cells (MDSCs) hyperinflammatory response in the lungs of COVID-19 patients

(2020) Malgorzata Kloc et al.   CELLULAR IMMUNOLOGY

Porcine epidemic diarrhea virus infections induce autophagy in Vero cells via ROS-dependent endoplasmic reticulum stress through PERK and IRE1 pathways

(2020) Pei Sun et al.   VETERINARY MICROBIOLOGY

Editorial: Alveolar Macrophages in Lung Inflammation and Resolution

(2019) Guochang Hu et al.   Frontiers in Immunology

The reactome pathway knowledgebase

(2019) Bijay Jassal et al.   NUCLEIC ACIDS RESEARCH

Renin-angiotensin-system, a potential pharmacological candidate, in acute respiratory distress syndrome during mechanical ventilation

(2019) Di Wang et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Nef-induced CCL2 Expression Contributes to HIV/SIV Brain Invasion and Neuronal Dysfunction

(2019) Michael H. Lehmann et al.   Frontiers in Immunology

Renin-Angiotensin System and Cardiovascular Functions

(2018) Chia-Hua Wu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Shared Features of Endothelial Dysfunction between Sepsis and Its Preceding Risk Factors (Aging and Chronic Disease)

(2018) Jesus Bermejo-Martin et al.   Journal of Clinical Medicine

Rho-specific Guanine nucleotide exchange factors (Rho-GEFs) inhibition affects macrophage phenotype and disrupts Golgi complex

(2017) Wei Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide

(2015) Marie Genin et al.   BMC CANCER

Human monocyte subsets exhibit divergent angiotensin I-converting activity

(2015) M. Rutkowska-Zapała et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Erythropoietin-induced hypertension and vascular injury in mice overexpressing human endothelin-1

(2014) Tlili Barhoumi et al.   JOURNAL OF HYPERTENSION

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

(2014) Nan Wang et al.   Frontiers in Immunology

Hydrogen Peroxide as a Damage Signal in Tissue Injury and Inflammation: Murderer, Mediator, or Messenger?

(2013) Albert van der Vliet et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Adult haemophagocytic syndrome

(2013) Manuel Ramos-Casals et al.   LANCET

Effects of Recombinant Human Erythropoietin on Resistance Artery Endothelial Function in Stage 4 Chronic Kidney Disease

(2013) Marie Briet et al.   Journal of the American Heart Association

Hyperactivity of the Ero1α Oxidase Elicits Endoplasmic Reticulum Stress but No Broad Antioxidant Response

(2012) Henning Gram Hansen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T Regulatory Lymphocytes Prevent Angiotensin II–Induced Hypertension and Vascular Injury

(2011) Tlili Barhoumi et al.   HYPERTENSION

T Regulatory Lymphocytes Prevent Aldosterone-Induced Vascular Injury

(2011) Daniel A. Kasal et al.   HYPERTENSION

The endothelium in acute lung injury/acute respiratory distress syndrome

(2009) Nikolaos A Maniatis et al.   Current Opinion in Critical Care

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

SARS coronavirus spike protein-induced innate immune response occurs via activation of the NF-κB pathway in human monocyte macrophages in vitro

(2009) Susan F. Dosch et al.   VIRUS RESEARCH