Metabolism of phenolics in coffee and plant-based foods by canonical pathways: an assessment of the role of fatty acid β-oxidation to generate biologically-active and -inactive intermediates

A Practitioner's Dilemma Mass Spectrometry‐Based Annotation and Identification of Human Plasma and Urinary Polyphenol Metabolites

(2022) Nikolai Kuhnert et al.   MOLECULAR NUTRITION & FOOD RESEARCH

In Vitro Faecal Fermentation of Monomeric and Oligomeric Flavan‐3‐ols: Catabolic Pathways and Stoichiometry

(2022) Giuseppe Di Pede et al.   MOLECULAR NUTRITION & FOOD RESEARCH

In vitro (poly)phenol catabolism of unformulated- and phytosome-formulated cranberry (Vaccinium macrocarpon) extracts

(2021) Letizia Bresciani et al.   FOOD RESEARCH INTERNATIONAL

Functional Characterisation of Three Glycine N-Acyltransferase Variants and the Effect on Glycine Conjugation to Benzoyl–CoA

(2021) Johann M. Rohwer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Variation in the Methylation of Caffeoylquinic Acids and Urinary Excretion of 3′‐methoxycinnamic acid‐4′‐Sulfate After Apple Consumption by Volunteers

(2021) Laura Rubió et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Urine metabolites for the identification of Onchocerca volvulus infections in patients from Cameroon

(2021) Vera Wewer et al.   Parasites & Vectors

In vivo study of the bioavailability and metabolic profile of (poly)phenols after sous-vide artichoke consumption

(2021) Maite Domínguez-Fernández et al.   FOOD CHEMISTRY

Multimodal biomarker discovery for active Onchocerca volvulus infection

(2021) Ole Lagatie et al.   PLoS Neglected Tropical Diseases

Bioavailability and metabolism of chlorogenic acids (acyl‐quinic acids) in humans

(2020) Michael N. Clifford et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Influence of Sex on Urinary Organic Acids: A Cross-Sectional Study in Children

(2020) Marianna Caterino et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anthocyanin Metabolites in Human Urine after the Intake of New Functional Beverages

(2020) Vicente Agulló et al.   MOLECULES

Coenzyme A and Its Thioester Pools in Obese Zucker and Zucker Diabetic Fatty Rats

(2020) Shigeru Chohnan et al.   Nutrients

A widely distributed metalloenzyme class enables gut microbial metabolism of host- and diet-derived catechols

(2020) Vayu Maini Rekdal et al.   eLife

Variations of flavonoid composition and antioxidant properties among different cultivars, fruit tissues and developmental stages of citrus fruits

(2020) Chunhua Zhu et al.   CHEMISTRY & BIODIVERSITY

Monomeric Flavanols Are More Efficient Substrates for Gut Microbiota Conversion to Hydroxyphenyl‐γ‐Valerolactone Metabolites Than Oligomeric Procyanidins: A Randomized, Placebo‐Controlled Human Intervention Trial

(2020) Wendy J Hollands et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation

(2020) Lucía Barbier-Torres et al.   Nature Communications

Recommendations for standardizing nomenclature for dietary (poly)phenol catabolites

(2020) Colin D Kay et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Transport alteration of 4-phenyl butyric acid mediated by a sodium- and proton-coupled monocarboxylic acid transporter system in ALS model cell lines (NSC-34) under inflammatory states

(2020) Asmita Gyawali et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

In vitro catabolism of 3′,4′-dihydroxycinnamic acid by human colonic microbiota

(2020) Maizatul Hasyima Omar et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Interindividual Differences in Human Intestinal Microbial Conversion of (−)-Epicatechin to Bioactive Phenolic Compounds

(2020) Chen Liu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The expression and prognostic value of GLYATL1 and its potential role in hepatocellular carcinoma

(2020) Renguo Guan et al.   Journal of Gastrointestinal Oncology

Pharmacokinetics, Tissue Distribution, Metabolism, and Excretion of Naringin in Aged Rats

(2019) Xuan Zeng et al.   Frontiers in Pharmacology

Procyanidin—Cell Wall Interactions within Apple Matrices Decrease the Metabolization of Procyanidins by the Human Gut Microbiota and the Anti-Inflammatory Effect of the Resulting Microbial Metabolome In Vitro

(2019) Carine Le Bourvellec et al.   Nutrients

Antiproliferative Activity and Cell Metabolism of Hydroxycinnamic Acids in Human Colon Adenocarcinoma Cell Lines

(2019) Serena Martini et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Characteristics of β-oxidative and reductive metabolism on the acyl side chain of cinnamic acid and its analogues in rats

(2019) Kai-jing Zhao et al.   ACTA PHARMACOLOGICA SINICA

Enzymatic Reactions Involving Ketyls: From a Chemical Curiosity to a General Biochemical Mechanism

(2019) Wolfgang Buckel   BIOCHEMISTRY

Herbs and Spices- Biomarkers of Intake Based on Human Intervention Studies – A Systematic Review

(2019) Rosa Vázquez-Fresno et al.   Genes and Nutrition

Phenolic Breakdown Products of Cyanidin and Quercetin Contribute to Protection against Mitochondrial Impairment and Reactive Oxygen Species Generation in an In Vitro Model of Hepatocyte Steatosis

(2019) Hossein Rafiei et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

3-(4-Hydroxy-3-methoxyphenyl)propionic Acid Produced from 4-Hydroxy-3-methoxycinnamic Acid by Gut Microbiota Improves Host Metabolic Condition in Diet-Induced Obese Mice

(2019) Ryuji Ohue-Kitano et al.   Nutrients

Preclinical Absorption, Distribution, Metabolism, and Excretion of Sodium Danshensu, One of the Main Water-Soluble Ingredients in Salvia miltiorrhiza, in Rats

(2019) Xiangguo Meng et al.   Frontiers in Pharmacology

Metabolomic Studies of Tissue Injury in Nonhuman Primates Exposed to Gamma-Radiation

(2019) Amrita K. Cheema et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism

(2019) Vayu Maini Rekdal et al.   SCIENCE

Flavanol Bioavailability in Two Cocoa Products with Different Phenolic Content. A Comparative Study in Humans

(2019) Miren Gómez-Juaristi et al.   Nutrients

Characterization of glycine‐ N ‐acyltransferase like 1 (GLYATL1) in prostate cancer

(2019) Marie‐Lisa Eich et al.   PROSTATE

Protocatechuic acid from chicory is bioavailable and undergoes partial glucuronidation and sulfation in healthy humans

(2019) Jiakun Zheng et al.   Food Science & Nutrition

Quantification of urinary derivatives of Phenylbutyric and Benzoic acids by LC-MS/MS as treatment compliance biomarkers in Urea Cycle disorders

(2019) Fernando Andrade et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Simultaneously Quantitative Analysis of Naringin and Its Major Human Gut Microbial Metabolites Naringenin and 3-(4′-Hydroxyphenyl) Propanoic Acid via Stable Isotope Deuterium-Labeling Coupled with RRLC-MS/MS Method

(2019) Taobin Chen et al.   MOLECULES

Quantification of Urinary Phenyl-γ-Valerolactones and Related Valeric Acids in Human Urine on Consumption of Apples

(2019) Andrea Anesi et al.   Metabolites

Metabolite Profiling of Naringin in Rat Urine and Feces Using Stable Isotope-Labeling-Based Liquid Chromatography-Mass Spectrometry

(2019) Xuan Zeng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Bioavailability and pharmacokinetic profile of grape pomace phenolic compounds in humans

(2018) Fabio Castello et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

New alkylresorcinol metabolites in spot urine as biomarkers of whole grain wheat and rye intake in a Swedish middle-aged population

(2018) Rikard Landberg et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Inter-individual variability in the production of flavan-3-ol colonic metabolites: preliminary elucidation of urinary metabotypes

(2018) Pedro Mena et al.   EUROPEAN JOURNAL OF NUTRITION

Absorption and metabolism of yerba mate phenolic compounds in humans

(2018) Miren Gómez-Juaristi et al.   FOOD CHEMISTRY

Phytochemical characterization of different prickly pear ( Opuntia ficus-indica (L.) Mill.) cultivars and botanical parts: UHPLC-ESI-MS n metabolomics profiles and their chemometric analysis

(2018) Pedro Mena et al.   FOOD RESEARCH INTERNATIONAL

Digestibility of (Poly)phenols and Antioxidant Activity in Raw and Cooked Cactus Cladodes (Opuntia ficus-indica)

(2018) Elsy De Santiago et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

In-vivo metabolite profiling of chicoric acid in rat plasma, urine and feces after oral administration using liquid chromatography quadrupole time of flight mass spectrometry

(2018) Zhijun Diao et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Mitochondrial β-oxidation of saturated fatty acids in humans

(2018) María M. Adeva-Andany et al.   MITOCHONDRION

Absorption, metabolism, distribution and excretion of (−)-epicatechin: A review of recent findings

(2018) Gina Borges et al.   MOLECULAR ASPECTS OF MEDICINE

Disorders of mitochondrial long-chain fatty acid oxidation and the carnitine shuttle

(2018) Suzan J. G. Knottnerus et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Bioavailability of hydroxycinnamates in an instant green/roasted coffee blend in humans. Identification of novel colonic metabolites

(2018) Miren Gómez-Juaristi et al.   Food & Function

Acute metabolic actions of the major polyphenols in chamomile: an in vitro mechanistic study on their potential to attenuate postprandial hyperglycaemia

(2018) Jose A. Villa-Rodriguez et al.   Scientific Reports

A critical evaluation of the use of gas chromatography- and high performance liquid chromatography-mass spectrometry techniques for the analysis of microbial metabolites in human urine after consumption of orange juice

(2018) José Luis Ordóñez et al.   JOURNAL OF CHROMATOGRAPHY A

Identification of naringin metabolites mediated by human intestinal microbes with stable isotope-labeling method and UFLC-Q-TOF-MS/MS

(2018) Taobin Chen et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Impact of Mitochondrial Fatty Acid Synthesis on Mitochondrial Biogenesis

(2018) Sara M. Nowinski et al.   CURRENT BIOLOGY

The Human Metabolism of Nuts Proanthocyanidins does not Reveal Urinary Metabolites Consistent with Distinctive Gut Microbiota Metabotypes

(2018) Adrián Cortés-Martín et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Coffee consumption and risk of nonalcoholic fatty liver disease

(2017) Karn Wijarnpreecha et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Identification and quantification of even and odd chained 5-n alkylresorcinols, branched chain-alkylresorcinols and methylalkylresorcinols in Quinoa (Chenopodium quinoa)

(2017) Alastair B. Ross et al.   FOOD CHEMISTRY

Chlorogenic acid versus amaranth's caffeoylisocitric acid – Gut microbial degradation of caffeic acid derivatives

(2017) Maren Vollmer et al.   FOOD RESEARCH INTERNATIONAL

Interindividual Variability in Metabolism of [6]-Shogaol by Gut Microbiota

(2017) Pei Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

New insights into the catalytic mechanism of human glycine N-acyltransferase

(2017) Rencia van der Sluis et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Effect of heat processing on thermal stability and antioxidant activity of six flavonoids

(2017) Hind Chaaban et al.   JOURNAL OF FOOD PROCESSING AND PRESERVATION

Identification of enzymes involved in oxidation of phenylbutyrate

(2017) Neža Palir et al.   JOURNAL OF LIPID RESEARCH

Novel urinary alkylresorcinol metabolites as biomarkers of whole grain intake in free-living Swedish adults

(2017) Roksana Wierzbicka et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Chlorogenic acids and the acyl-quinic acids: discovery, biosynthesis, bioavailability and bioactivity

(2017) Michael N. Clifford et al.   NATURAL PRODUCT REPORTS

Averrhoa carambola free phenolic extract ameliorates nonalcoholic hepatic steatosis by modulating mircoRNA-34a, mircoRNA-33 and AMPK pathways in leptin receptor-deficient db/db mice

(2017) Daorui Pang et al.   Food & Function

The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders

(2016) Sander M. Houten et al.   Annual Review of Physiology

Butyric acid increases transepithelial transport of ferulic acid through upregulation of the monocarboxylate transporters SLC16A1 (MCT1) and SLC16A3 (MCT4)

(2016) Kerstin Ziegler et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Carnitine transport and fatty acid oxidation

(2016) Nicola Longo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Breakfast consumption induces retarded release of chlorogenic acid metabolites in humans

(2016) D. Scherbl et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

Catabolism of citrus flavanones by the probiotics Bifidobacterium longum and Lactobacillus rhamnosus

(2016) Gema Pereira-Caro et al.   EUROPEAN JOURNAL OF NUTRITION

Xenobiotic/medium chain fatty acid: CoA ligase – a critical review on its role in fatty acid metabolism and the detoxification of benzoic acid and aspirin

(2016) Rencia van der Sluis et al.   Expert Opinion on Drug Metabolism & Toxicology

LC-MS n study of the chemical transformations of hydroxycinnamates during yerba maté ( Ilex paraguariensis ) tea brewing

(2016) Marius Febi Matei et al.   FOOD RESEARCH INTERNATIONAL

Impact of chlorogenic acids from coffee on urine metabolome in healthy human subjects

(2016) Francisco Madrid-Gambin et al.   FOOD RESEARCH INTERNATIONAL

A comprehensive evaluation of the [2- 14 C](–)-epicatechin metabolome in rats

(2016) Gina Borges et al.   FREE RADICAL BIOLOGY AND MEDICINE

Identification of Plasma and Urinary Metabolites and Catabolites Derived from Orange Juice (Poly)phenols: Analysis by High-Performance Liquid Chromatography–High-Resolution Mass Spectrometry

(2016) Gema Pereira-Caro et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Metabolic profile of esculin in rats by ultra high performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry

(2016) Yinan Wang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Metabonomic study of the effects of different acupuncture directions on therapeutic efficacy

(2016) Liang Ju et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Short- and medium-chain fatty acids in energy metabolism: the cellular perspective

(2016) Peter Schönfeld et al.   JOURNAL OF LIPID RESEARCH

Urinary excretion ofCitrusflavanones and their major catabolites after consumption of fresh oranges and pasteurized orange juice: A randomized cross-over study

(2016) Julian K. Aschoff et al.   MOLECULAR NUTRITION & FOOD RESEARCH

In Vivo and In Vitro Evidence for Brain Uptake of 4-Phenylbutyrate by the Monocarboxylate Transporter 1 (MCT1)

(2016) Na-Young Lee et al.   PHARMACEUTICAL RESEARCH

Impacts on Sirtuin Function and Bioavailability of the Dietary Bioactive Compound Dihydrocoumarin

(2016) Jennifer L. Jacobi et al.   PLoS One

Urinary excretions of 34 dietary polyphenols and their associations with lifestyle factors in the EPIC cohort study

(2016) Raul Zamora-Ros et al.   Scientific Reports

The metabolome of [2-14C](−)-epicatechin in humans: implications for the assessment of efficacy, safety and mechanisms of action of polyphenolic bioactives

(2016) Javier I. Ottaviani et al.   Scientific Reports

Serum biomarkers of habitual coffee consumption may provide insight into the mechanism underlying the association between coffee consumption and colorectal cancer

(2015) K. A. Guertin et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Biotransformation of (−)-Epigallocatechin and (−)-Gallocatechin by Intestinal Bacteria Involved in Isoflavone Metabolism

(2015) Akiko Takagaki et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Comparison of plasma alkylresorcinols (AR) and urinary AR metabolites as biomarkers of compliance in a short-term, whole-grain intervention study

(2015) Nicola M. McKeown et al.   EUROPEAN JOURNAL OF NUTRITION

Chronic administration of a microencapsulated probiotic enhances the bioavailability of orange juice flavanones in humans

(2015) Gema Pereira-Caro et al.   FREE RADICAL BIOLOGY AND MEDICINE

Profiling a gut microbiota-generated catechin metabolite's fate in human blood cells using a metabolomic approach

(2015) Melanie Mülek et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Determination of phenolic compounds by ultra high liquid chromatography-tandem mass spectrometry: Applications in nuts

(2015) Mine Gültekin-Özgüven et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

Comparative biokinetics and metabolism of pure monomeric, dimeric, and polymeric flavan-3-ols: A randomized cross-over study in humans

(2015) Stefanie Wiese et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Gastrointestinal absorption and metabolism of hesperetin-7-O-rutinoside and hesperetin-7-O-glucoside in healthy humans

(2015) Lucas Actis-Goretta et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Discovery of urinary biomarkers of whole grain rye intake in free-living subjects using nontargeted LC-MS metabolite profiling

(2015) Kati Hanhineva et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Hypocholesterolemic and choleretic effects of three dimethoxycinnamic acids in relation to 2,4,5-trimethoxycinnamic acid in rats fed with a high-cholesterol/cholate diet

(2015) Manuel Serna et al.   Pharmacological Reports

Toxicity, cytotoxicity and lifespan induction studies of cider, apple and 3-(2-hydroxyphenyl)propionic acid

(2015) T. Merinas-Amo et al.   TOXICOLOGY LETTERS

Orange juice (poly)phenols are highly bioavailable in humans

(2014) Gema Pereira-Caro et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The pharmacokinetics of anthocyanins and their metabolites in humans

(2014) R M de Ferrars et al.   BRITISH JOURNAL OF PHARMACOLOGY

Absolute Configuration of (-)-2-(4-Hydroxyphenyl)propionic acid: Stereochemistry of Soy Isoflavone Metabolism

(2014) Mihyang Kim et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Study of the Catabolism of Thyme Phenols Combining in Vitro Fermentation and Human Intervention

(2014) Juana I. Mosele et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Simultaneous Pharmacokinetic Modeling of Alkylresorcinols and Their Main Metabolites Indicates Dual Absorption Mechanisms and Enterohepatic Elimination in Humans

(2014) Matti Marklund et al.   JOURNAL OF NUTRITION

Rapid and Sustained Systemic Circulation of Conjugated Gut Microbial Catabolites after Single-Dose Black Tea Extract Consumption

(2014) John van Duynhoven et al.   JOURNAL OF PROTEOME RESEARCH

Identification of Aromatic Fatty Acids in Butter Fat

(2014) Markus Schröder et al.   JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY

Nutrimetabolomics fingerprinting to identify biomarkers of bread exposure in a free-living population from the PREDIMED study cohort

(2014) Mar Garcia-Aloy et al.   Metabolomics

Biotransformation of tea polyphenols by gut microbiota

(2014) Huadong Chen et al.   Journal of Functional Foods

Coffee: biochemistry and potential impact on health

(2014) Iziar A. Ludwig et al.   Food & Function

Impact of dose on the bioavailability of coffee chlorogenic acids in humans

(2014) Angélique Stalmach et al.   Food & Function

Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a 13C-tracer study

(2013) Charles Czank et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

p-Coumaric acid modulates glucose and lipid metabolism via AMP-activated protein kinase in L6 skeletal muscle cells

(2013) Seon-A Yoon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sinapic Acid and Its Derivatives: Natural Sources and Bioactivity

(2013) Neda Nićiforović et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Metabolomic analyses of faeces reveals malabsorption in cirrhotic patients

(2013) Hai-jun Huang et al.   DIGESTIVE AND LIVER DISEASE

The isomerase and hydratase reaction mechanism of the crotonase active site of the multifunctional enzyme (type-1), as deduced from structures of complexes with 3S-hydroxy-acyl-CoA

(2013) Prasad Kasaragod et al.   FEBS Journal

Biotransformation of 4,5-O-dicaffeoylquinic acid methyl ester by human intestinal flora and evaluation on their inhibition of NO production and antioxidant activity of the products

(2013) Xiu-Wei Yang et al.   FOOD AND CHEMICAL TOXICOLOGY

Hepatic biotransformation of alkylresorcinols is mediated via cytochrome P450 and β-oxidation: A proof of concept study

(2013) Matti Marklund et al.   FOOD CHEMISTRY

Chain Length of Dietary Alkylresorcinols Affects Their In Vivo Elimination Kinetics in Rats

(2013) Matti Marklund et al.   JOURNAL OF NUTRITION

Identification and Pharmacokinetics of Novel Alkylresorcinol Metabolites in Human Urine, New Candidate Biomarkers for Whole-Grain Wheat and Rye Intake

(2013) Yingdong Zhu et al.   JOURNAL OF NUTRITION

Metabolomic fingerprint in patients at high risk of cardiovascular disease by cocoa intervention

(2013) Rafael Llorach et al.   MOLECULAR NUTRITION & FOOD RESEARCH

UPLC-QTOF/MS metabolic profiling unveils urinary changes in humans after a whole grain rye versus refined wheat bread intervention

(2013) Isabel Bondia-Pons et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Development of an isotope labeling ultra-high performance liquid chromatography mass spectrometric method for quantification of acylglycines in human urine

(2012) Avalyn Stanislaus et al.   ANALYTICA CHIMICA ACTA

Structural Elucidation and Quantification of Phenolic Conjugates Present in Human Urine after Tea Intake

(2012) Justin J. J. van der Hooft et al.   ANALYTICAL CHEMISTRY

Effect of diet composition on coenzyme A and its thioester pools in various rat tissues

(2012) Yuka Tokutake et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Designation of enzyme activity of glycine-N-acyltransferase family genes and depression of glycine-N-acyltransferase in human hepatocellular carcinoma

(2012) Moe Matsuo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Metabolic differences underlying two distinct rat urinary phenotypes, a suggested role for gut microbial metabolism of phenylalanine and a possible connection to autism

(2012) T. Andrew Clayton   FEBS LETTERS

Headspace fingerprinting as an untargeted approach to compare novel and traditional processing technologies: A case-study on orange juice pasteurisation

(2012) Liesbeth Vervoort et al.   FOOD CHEMISTRY

Antioxidant Activity of Phenolic Acids and Their Metabolites: Synthesis and Antioxidant Properties of the Sulfate Derivatives of Ferulic and Caffeic Acids and of the Acyl Glucuronide of Ferulic Acid

(2012) A. Piazzon et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Absorption, Disposition, Metabolism, and Excretion of [3-14C]Caffeic Acid in Rats

(2012) Maizatul H. Omar et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Investigating the Chemical Changes of Chlorogenic Acids during Coffee Brewing: Conjugate Addition of Water to the Olefinic Moiety of Chlorogenic Acids and Their Quinides

(2012) Marius Febi Matei et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Hippuric Acid in 24-Hour Urine Collections Is a Potential Biomarker for Fruit and Vegetable Consumption in Healthy Children and Adolescents

(2012) Danika Krupp et al.   JOURNAL OF NUTRITION

Gastrointestinal stability and bioavailability of (poly)phenolic compounds following ingestion of Concord grape juice by humans

(2012) Angelique Stalmach et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Absorption of dimethoxycinnamic acid derivatives in vitro and pharmacokinetic profile in human plasma following coffee consumption

(2012) Tracy L. Farrell et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Dose-dependent absorption of chlorogenic acids in the small intestine assessed by coffee consumption in ileostomists

(2012) Thomas Erk et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Metabolism of Methyleugenol in Liver Microsomes and Primary Hepatocytes: Pattern of Metabolites, Cytotoxicity, and DNA-Adduct Formation

(2012) Alexander T. Cartus et al.   TOXICOLOGICAL SCIENCES

Colonic catabolism of dietary phenolic and polyphenolic compounds from Concord grape juice

(2012) Angelique Stalmach et al.   Food & Function

Lipophilicity of acidic compounds: Impact of ion pair partitioning on drug design

(2011) Mark C. Wenlock et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Iso-glucuronides

(2011) Ronald G. Dickinson   CURRENT DRUG METABOLISM

Absorption and Metabolism of Chlorogenic Acids in Cultured Gastric Epithelial Monolayers

(2011) T. L. Farrell et al.   DRUG METABOLISM AND DISPOSITION

Comparative study on antioxidant capacity of flavonoids and their inhibitory effects on oleic acid-induced hepatic steatosis in vitro

(2011) Di Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Biotransformation of phlorizin by human intestinal flora and inhibition of biotransformation products on tyrosinase activity

(2011) Li-Qin Zhang et al.   FOOD CHEMISTRY

Metabolic pathways of the colonic metabolism of flavonoids (flavonols, flavones and flavanones) and phenolic acids

(2011) Aida Serra et al.   FOOD CHEMISTRY

Identification of (Poly)phenolic Compounds in Concord Grape Juice and Their Metabolites in Human Plasma and Urine after Juice Consumption

(2011) Angelique Stalmach et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Determination of Microbial Phenolic Acids in Human Faeces by UPLC-ESI-TQ MS

(2011) Fernando Sánchez-Patán et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Determinants of Aspirin Metabolism in Healthy Men and Women: Effects of Dietary Inducers of UDP-Glucuronosyltransferases

(2011) Sandi L. Navarro et al.   Journal of Nutrigenetics and Nutrigenomics

Characterization of hydroxycinnamic acid glucuronide and sulfate conjugates by HPLC–DAD–MS2: Enhancing chromatographic quantification and application in Caco-2 cell metabolism

(2011) Tracy Farrell et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Brain Mitochondrial Drug Delivery: Influence of Drug Physicochemical Properties

(2011) Shelley A. Durazo et al.   PHARMACEUTICAL RESEARCH

Bioavailability of chlorogenic acids following acute ingestion of coffee by humans with an ileostomy

(2010) Angélique Stalmach et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Metabolism of green tea catechins by the human small intestine

(2010) Markus Schantz et al.   Biotechnology Journal

Colonic metabolites of berry polyphenols: the missing link to biological activity?

(2010) Gary Williamson et al.   BRITISH JOURNAL OF NUTRITION

Profile and Characterization of the Chlorogenic Acids in Green Robusta Coffee Beans by LC-MSn: Identification of Seven New Classes of Compounds

(2010) Rakesh Jaiswal et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Effect of Milk on the Urinary Excretion of Microbial Phenolic Acids after Cocoa Powder Consumption in Humans

(2010) Mireia Urpi-Sarda et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Metabolism of (−)-Epigallocatechin Gallate by Rat Intestinal Flora

(2010) Akiko Takagaki et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Bioavailability of Various Polyphenols from a Diet Containing Moderate Amounts of Berries†

(2010) Raika Koli et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A Method for Comprehensive Analysis of Urinary Acylglycines by Using Ultra-Performance Liquid Chromatography Quadrupole Linear Ion Trap Mass Spectrometry

(2010) Avalyn E. Lewis-Stanislaus et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Increased urinary excretion of a 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA), an abnormal phenylalanine metabolite ofClostridiaspp. in the gastrointestinal tract, in urine samples from patients with autism and schizophrenia

(2010) William Shaw   NUTRITIONAL NEUROSCIENCE

Profiling and characterisation by liquid chromatography/multi-stage mass spectrometry of the chlorogenic acids in Gardeniae Fructus

(2010) Michael N. Clifford et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Genetic polymorphisms of Glycine N-acyltransferase (GLYAT) in a French Caucasian population

(2010) Christian Lacks Lino Cardenas et al.   XENOBIOTICA

The Mechanisms of Human Hotdog-fold Thioesterase 2 (hTHEM2) Substrate Recognition and Catalysis Illuminated by a Structure and Function Based Analysis†,‡

(2009) Jian Cao et al.   BIOCHEMISTRY

Genetic Polymorphisms of Glycine N-acyltransferase in Japanese Individuals

(2009) Akiko Yamamoto et al.   Drug Metabolism and Pharmacokinetics

Green Tea Flavan-3-ols: Colonic Degradation and Urinary Excretion of Catabolites by Humans

(2009) Suri Roowi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Targeted metabolic profiling of phenolics in urine and plasma after regular consumption of cocoa by liquid chromatography–tandem mass spectrometry

(2009) Mireia Urpi-Sarda et al.   JOURNAL OF CHROMATOGRAPHY A

The Bioavailability of Apigenin-7-Glucoside Is Influenced by Human Intestinal Microbiota in Rats

(2009) Laura Hanske et al.   JOURNAL OF NUTRITION

In vitro and in vivo conjugation of dietary hydroxycinnamic acids by UDP-glucuronosyltransferases and sulfotransferases in humans

(2009) Chi Chun Wong et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

An LC-MS-Based Metabolomics Approach for Exploring Urinary Metabolome Modifications after Cocoa Consumption

(2009) Rafael Llorach et al.   JOURNAL OF PROTEOME RESEARCH

A comparison of the in vitro biotransformation of (-)-epicatechin and procyanidin B2 by human faecal microbiota

(2009) Stavroula Stoupi et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The red clover isoflavone irilone is largely resistant to degradation by the human gut microbiota

(2009) Annett Braune et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Toxicology and risk assessment of coumarin: Focus on human data

(2009) Klaus Abraham et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Metabolism of protocatechuic acid influences fatty acid oxidation in rat heart: New anti-angina mechanism implication

(2008) Yan-guang Cao et al.   BIOCHEMICAL PHARMACOLOGY

Simultaneous determination of the flavonoid aglycones diosmetin and hesperetin in human plasma and urine by a validated GC/MS method:in vivometabolic reduction of diosmetin to hesperetin

(2008) Marios Spanakis et al.   BIOMEDICAL CHROMATOGRAPHY

2,4,5-trimethoxycinnamic acid: the major metabolite of α-asarone, retains most of the pharmacological properties of α-asarone

(2008) Javier Antunez-Solis et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Novel and potent inhibitors of fatty acid synthase derived from catechins and their inhibition on MCF-7 cells

(2008) Shu-Yan Zhang et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Structural identification of novel glucoside and glucuronide metabolites of (−)-epigallocatechin-3-gallate in mouse urine using liquid chromatography/electrospray ionization tandem mass spectrometry

(2008) Shengmin Sang et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Investigation of the metabolic fate of dihydrocaffeic acid

(2007) Laure Poquet et al.   BIOCHEMICAL PHARMACOLOGY