Short- and medium-chain fatty acids in energy metabolism: the cellular perspective

Revisiting the metabolism and physiological functions of caprylic acid (C8:0) with special focus on ghrelin octanoylation

(2016) Fanny Lemarié et al.   BIOCHIMIE

Medium-chain fatty acids inhibit mitochondrial metabolism in astrocytes promoting astrocyte–neuron lactate and ketone body shuttle systems

(2016) Jonathan Thevenet et al.   FASEB JOURNAL

The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging

(2015) Michael E. Walsh et al.   AGING CELL

Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporeal membrane oxygenation in an infant swine model

(2015) Masaki Kajimoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The role of short chain fatty acids in appetite regulation and energy homeostasis

(2015) C S Byrne et al.   INTERNATIONAL JOURNAL OF OBESITY

Effects of Different Fatty Acid Chain Lengths on Fatty Acid Oxidation-Related Protein Expression Levels in Rat Skeletal Muscles

(2015) Rie Ishizawa et al.   Journal of Oleo Science

Reduced severity of ischemic stroke and improvement of mitochondrial function after dietary treatment with the anaplerotic substance triheptanoin

(2015) T.M. Schwarzkopf et al.   NEUROSCIENCE

Role of free fatty acid receptors in the regulation of energy metabolism

(2014) Takafumi Hara et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Dynamic carbon 13 breath tests for the study of liver function and gastric emptying

(2014) L. Bonfrate et al.   Gastroenterology Report

Induction of Apoptosis by the Medium-Chain Length Fatty Acid Lauric Acid in Colon Cancer Cells due to Induction of Oxidative Stress

(2013) J.K. Fauser et al.   CHEMOTHERAPY

Butyrate and Colorectal Cancer: The Role of Butyrate Transport

(2013) Pedro Gonçalves et al.   CURRENT DRUG METABOLISM

Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria

(2013) Irina V. Perevoshchikova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of the gut microbiota in human nutrition and metabolism

(2013) Balakrishnan S Ramakrishna   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Contrasting metabolic effects of medium- versus long-chain fatty acids in skeletal muscle

(2013) Magdalene K. Montgomery et al.   JOURNAL OF LIPID RESEARCH

Triheptanoin partially restores levels of tricarboxylic acid cycle intermediates in the mouse pilocarpine model of epilepsy

(2013) Mussie G. Hadera et al.   JOURNAL OF NEUROCHEMISTRY

Impact of Short- and Medium-Chain Fatty Acids on Mitochondrial Function in Severe Inflammation

(2013) Matthias Hecker et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Regulation of energy metabolism by long-chain fatty acids

(2013) Manabu T. Nakamura et al.   PROGRESS IN LIPID RESEARCH

The emerging role of acyl-CoA thioesterases and acyltransferases in regulating peroxisomal lipid metabolism

(2012) Mary C. Hunt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Heptanoate as a Neural Fuel: Energetic and Neurotransmitter Precursors in Normal and Glucose Transporter I-Deficient (G1D) Brain

(2012) Isaac Marin-Valencia et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Medium Chain Fatty Acids Are Selective Peroxisome Proliferator Activated Receptor (PPAR) γ Activators and Pan-PPAR Partial Agonists

(2012) Marcelo Vizoná Liberato et al.   PLoS One

PPARs: Fatty acid sensors controlling metabolism

(2012) Lars la Cour Poulsen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mechanisms of Gene Regulation by Fatty Acids

(2012) Anastasia Georgiadi et al.   Advances in Nutrition

A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart

(2011) Mark A. Cole et al.   BASIC RESEARCH IN CARDIOLOGY

Brown adipose tissue mitochondria oxidizing fatty acids generate high levels of reactive oxygen species irrespective of the uncoupling protein-1 activity state

(2011) Peter Schönfeld et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Triheptanoin—A medium chain triglyceride with odd chain fatty acids: A new anaplerotic anticonvulsant treatment?

(2011) Karin Borges et al.   EPILEPSY RESEARCH

Long- and Medium-Chain Fatty Acids Induce Insulin Resistance to a Similar Extent in Humans Despite Marked Differences in Muscle Fat Accumulation

(2011) Joris Hoeks et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Toxicity of octanoate and decanoate in rat peripheral tissues: evidence of bioenergetic dysfunction and oxidative damage induction in liver and skeletal muscle

(2011) Giselli Scaini et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

A metabolic link between mitochondrial ATP synthesis and liver glycogen metabolism: NMR study in rats re-fed with butyrate and/or glucose

(2011) Jean-Louis Gallis et al.   Nutrition & Metabolism

Dietary long-chain, but not medium-chain, triglycerides impair exercise performance and uncouple cardiac mitochondria in rats

(2011) Andrew J Murray et al.   Nutrition & Metabolism

Mitochondrial fatty acid oxidation and oxidative stress: Lack of reverse electron transfer-associated production of reactive oxygen species

(2010) Peter Schönfeld et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms

(2010) Sa'ad H. Al-Lahham et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Short-chain fatty acids induced autophagy serves as an adaptive strategy for retarding mitochondria-mediated apoptotic cell death

(2010) Y Tang et al.   CELL DEATH AND DIFFERENTIATION

13C-breath tests for clinical investigation of liver mitochondrial function

(2010) Ignazio Grattagliano et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Liver fatty acid-binding protein and obesity

(2010) Barbara P. Atshaves et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Acetate metabolism and aging: An emerging connection

(2010) Tadahiro Shimazu et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Anticonvulsant effects of a triheptanoin diet in two mouse chronic seizure models

(2010) Sarah Willis et al.   NEUROBIOLOGY OF DISEASE

Comparative Analyses of Disease Risk Genes Belonging to the Acyl-CoA Synthetase Medium-Chain (ACSM) Family in Human Liver and Cell Lines

(2009) Inka Boomgaarden et al.   BIOCHEMICAL GENETICS

Fasting-Induced Hypothermia and Reduced Energy Production in Mice Lacking Acetyl-CoA Synthetase 2

(2009) Iori Sakakibara et al.   Cell Metabolism

Short chain fatty acids exchange across the gut and liver in humans measured at surgery

(2009) Johanne G. Bloemen et al.   CLINICAL NUTRITION

Enhancement of Muscle Mitochondrial Oxidative Capacity and Alterations in Insulin Action Are Lipid Species Dependent: Potent Tissue-Specific Effects of Medium-Chain Fatty Acids

(2009) N. Turner et al.   DIABETES

Electron Transport Chain-dependent and -independent Mechanisms of Mitochondrial H2O2Emission during Long-chain Fatty Acid Oxidation

(2009) Erin L. Seifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxygen Sensitivity of Mitochondrial Reactive Oxygen Species Generation Depends on Metabolic Conditions

(2009) David L. Hoffman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the AMP activated protein kinase by short-chain fatty acids is the main mechanism underlying the beneficial effect of a high fiber diet on the metabolic syndrome

(2009) Guo-Xin Hu et al.   MEDICAL HYPOTHESES

Medium-chain fatty acids accumulating in MCAD deficiency elicit lipid and protein oxidative damage and decrease non-enzymatic antioxidant defenses in rat brain

(2009) Patrícia F. Schuck et al.   NEUROCHEMISTRY INTERNATIONAL

Within brown-fat cells, UCP1-mediated fatty acid-induced uncoupling is independent of fatty acid metabolism

(2008) Irina G. Shabalina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Impact of short- and medium-chain organic acids, acylcarnitines, and acyl-CoAs onmitochondrial energy metabolism

(2008) Sven Wolfgang Sauer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Medium-chain Fatty Acids as Metabolic Therapy in Cardiac Disease

(2008) François Labarthe et al.   CARDIOVASCULAR DRUGS AND THERAPY

Fatty acids as modulators of the cellular production of reactive oxygen species

(2008) Peter Schönfeld et al.   FREE RADICAL BIOLOGY AND MEDICINE

Evidence for involvement of nonesterified fatty acid-induced protonophoric uncoupling during mitochondrial dysfunction caused by hypoxia and reoxygenation

(2008) T. Feldkamp et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION