Food Additives, a Key Environmental Factor in the Development of IBD through Gut Dysbiosis

Factors Conditioning the Potential Effects TiO2 NPs Exposure on Human Microbiota: a Mini-Review

(2021) Ewa Baranowska-Wójcik   BIOLOGICAL TRACE ELEMENT RESEARCH

High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice

(2021) Joan Serrano et al.   Microbiome

Nanoparticles in the Food Industry and Their Impact on Human Gut Microbiome and Diseases

(2021) Merry Ghebretatios et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Impact of Food Additive Titanium Dioxide on Gut Microbiota Composition, Microbiota-Associated Functions, and Gut Barrier: A Systematic Review of In Vivo Animal Studies

(2021) Emanuele Rinninella et al.   International Journal of Environmental Research and Public Health

Food colorants metabolized by commensal bacteria promote colitis in mice with dysregulated expression of interleukin-23

(2021) Zhengxiang He et al.   Cell Metabolism

Impact of Rapeseed and Soy Lecithin on Postprandial Lipid Metabolism, Bile Acid Profile, and Gut Bacteria in Mice

(2021) Chloé Robert et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Food and Food Groups in Inflammatory Bowel Disease (IBD): The Design of the Groningen Anti-Inflammatory Diet (GrAID)

(2021) Marjo J. E. Campmans-Kuijpers et al.   Nutrients

Direct impact of commonly used dietary emulsifiers on human gut microbiota

(2021) Sabrine Naimi et al.   Microbiome

Maternal Emulsifier P80 Intake Induces Gut Dysbiosis in Offspring and Increases Their Susceptibility to Colitis in Adulthood

(2021) Ge Jin et al.   mSystems

Safety assessment of titanium dioxide (E171) as a food additive

(2021) et al.   EFSA Journal

Interaction between Lipopolysaccharide and Gut Microbiota in Inflammatory Bowel Diseases

(2021) Marcello Candelli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Acesulfame potassium induces dysbiosis and intestinal injury with enhanced lymphocyte migration to intestinal mucosa

(2021) Yoshinori Hanawa et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Can control of gut microbiota be a future therapeutic option for inflammatory bowel disease?

(2021) Atsushi Nishida et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease

(2021) Eliza Starz et al.   Nutrients

Association of ultra-processed food intake with risk of inflammatory bowel disease: prospective cohort study

(2021) Neeraj Narula et al.   BMJ-British Medical Journal

Editorial: Food Additives, Cooking and Processing: Impact on the Microbiome

(2021) Xi Yu et al.   Frontiers in Nutrition

Vitamin D and colorectal cancer: Chemopreventive perspectives through the gut microbiota and the immune system

(2021) Emanuele Rinninella et al.   BIOFACTORS

Consumo crónico de edulcorantes en ratones y su efecto sobre el sistema inmunitario y la microbiota del intestino delgado

(2021) Jorge Alberto Escoto et al.   Biomedica

The Emulsifier Carboxymethylcellulose Induces More Aggressive Colitis in Humanized Mice with Inflammatory Bowel Disease Microbiota Than Polysorbate-80

(2021) Esmat Rousta et al.   Nutrients

Artificial Sweeteners: History and New Concepts on Inflammation

(2021) Abigail Raffner Basson et al.   Frontiers in Nutrition

Randomized Controlled-Feeding Study of Dietary Emulsifier Carboxymethylcellulose Reveals Detrimental Impacts on the Gut Microbiota and Metabolome

(2021) Benoit Chassaing et al.   GASTROENTEROLOGY

ESPEN practical guideline: Clinical Nutrition in inflammatory bowel disease

(2020) Stephan C. Bischoff et al.   CLINICAL NUTRITION

Adherence to a Mediterranean diet is associated with a lower risk of later-onset Crohn’s disease: results from two large prospective cohort studies

(2020) Hamed Khalili et al.   GUT

Low FODMAP Diet: Evidence, Doubts, and Hopes

(2020) Massimo Bellini et al.   Nutrients

Interaction between microbiota and immunity in health and disease

(2020) Danping Zheng et al.   CELL RESEARCH

Acute high‐dose titanium dioxide nanoparticle exposure alters gastrointestinal homeostasis in mice

(2020) Courtney C. Kurtz et al.   JOURNAL OF APPLIED TOXICOLOGY

Impact of food additives on the composition and function of gut microbiota: A review

(2020) Yu Cao et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Modulation of the Gut Microbiota during High-Dose Glycerol Monolaurate-Mediated Amelioration of Obesity in Mice Fed a High-Fat Diet

(2020) Minjie Zhao et al.   mBio

Gluten‐Free Diet in IBD: Time for a Recommendation?

(2020) Kimberly N. Weaver et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Food additive emulsifiers: a review of their role in foods, legislation and classifications, presence in food supply, dietary exposure, and safety assessment

(2020) Selina Cox et al.   NUTRITION REVIEWS

Foodborne Titanium Dioxide Nanoparticles Induce Stronger Adverse Effects in Obese Mice than Non‐Obese Mice: Gut Microbiota Dysbiosis, Colonic Inflammation, and Proteome Alterations

(2020) Xiaoqiong Cao et al.   Small

Artificial Sweeteners Disrupt Tight Junctions and Barrier Function in the Intestinal Epithelium through Activation of the Sweet Taste Receptor, T1R3

(2020) Aparna Shil et al.   Nutrients

Sucralose Promotes Colitis-Associated Colorectal Cancer Risk in a Murine Model Along With Changes in Microbiota

(2020) Xueting Li et al.   Frontiers in Oncology

Alterations of Akkermansia muciniphila in the inflammatory bowel disease patients with washed microbiota transplantation

(2020) Ting Zhang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The hidden hazardous effects of stevia and sucralose consumption in male and female albino mice in comparison to sucrose

(2020) Alyaa Farid et al.   SAUDI PHARMACEUTICAL JOURNAL

Diet and Nutrients in Gastrointestinal Chronic Diseases

(2020) Antonio Corsello et al.   Nutrients

Emulsifiers Impact Colonic Length in Mice and Emulsifier Restriction is Feasible in People with Crohn’s Disease

(2020) Alicia M. Sandall et al.   Nutrients

Dietary Emulsifiers Directly Impact Adherent-Invasive E. coli Gene Expression to Drive Chronic Intestinal Inflammation

(2020) Emilie Viennois et al.   Cell Reports

The development of metabolic endotoxemia is dependent on the type of sweetener and the presence of saturated fat in the diet

(2020) Mónica Sánchez-Tapia et al.   Gut Microbes

Food Additives, Gut Microbiota, and Irritable Bowel Syndrome: A Hidden Track

(2020) Emanuele Rinninella et al.   International Journal of Environmental Research and Public Health

Processed meat products with added plant antioxidants affect the microbiota and immune response in C57BL/6JRj mice with cyclically induced chronic inflammation

(2020) Stina Burri et al.   BIOMEDICINE & PHARMACOTHERAPY

Human gut microbes are susceptible to antimicrobial food additives in vitro

(2019) Lucia Hrncirova et al.   FOLIA MICROBIOLOGICA

Chlorogenic Acid Ameliorates Colitis and Alters Colonic Microbiota in a Mouse Model of Dextran Sulfate Sodium-Induced Colitis

(2019) Peng Zhang et al.   Frontiers in Physiology

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

(2019) Jason Lloyd-Price et al.   NATURE

Implications of the Westernized Diet in the Onset and Progression of IBD

(2019) Fernando Rizzello et al.   Nutrients

Chlorogenic Acid Attenuates Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice through MAPK/ERK/JNK Pathway

(2019) Wenyan Gao et al.   Biomed Research International

Dietary emulsifier polysorbate‐80 induces small‐intestinal vulnerability to indomethacin‐induced lesions via dysbiosis

(2019) Hirotaka Furuhashi et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Glycerol Monolaurate‐Mediated Attenuation of Metabolic Syndrome is Associated with the Modulation of Gut Microbiota in High Fat diet‐fed Mice

(2019) Minjie Zhao et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Diet–microbiota interactions and personalized nutrition

(2019) Aleksandra A. Kolodziejczyk et al.   NATURE REVIEWS MICROBIOLOGY

Food Preservatives Induce Proteobacteria Dysbiosis in Human-Microbiota Associated Nod2-Deficient Mice

(2019) Hrncirova et al.   Microorganisms

Food Components and Dietary Habits: Keys for a Healthy Gut Microbiota Composition

(2019) Rinninella et al.   Nutrients

The impact of food additives, artificial sweeteners and domestic hygiene products on the human gut microbiome and its fibre fermentation capacity

(2019) Konstantinos Gerasimidis et al.   EUROPEAN JOURNAL OF NUTRITION

The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn’s Disease–Like Ileitis

(2018) Alexander Rodriguez-Palacios et al.   INFLAMMATORY BOWEL DISEASES

Sucralose Increased Susceptibility to Colitis in Rats

(2018) Xiuhong Wang et al.   INFLAMMATORY BOWEL DISEASES

Nutrition in Pediatric Inflammatory Bowel Disease

(2018) Erasmo Miele et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Effects of the Artificial Sweetener Neotame on the Gut Microbiome and Fecal Metabolites in Mice

(2018) Liang Chi et al.   MOLECULES

Enteral Nutrition for Pediatric Crohn's Disease: An Underutilized Therapy

(2018) Ala K. Shaikhkhalil et al.   NUTRITION IN CLINICAL PRACTICE

Artificial sweetener saccharin disrupts intestinal epithelial cells’ barrier function in vitro

(2018) P. S. Santos et al.   Food & Function

Chronic Consumption of Sweeteners and Its Effect on Glycaemia, Cytokines, Hormones, and Lymphocytes of GALT in CD1 Mice

(2018) Cristian Angel Rosales-Gómez et al.   Biomed Research International

Toll-like Receptors and Inflammatory Bowel Disease

(2018) Yue Lu et al.   Frontiers in Immunology

Chlorogenic acid ameliorates experimental colitis in mice by suppressing signaling pathways involved in inflammatory response and apoptosis

(2018) Iva Vukelić et al.   FOOD AND CHEMICAL TOXICOLOGY

Review article: emulsifiers in the food supply and implications for gastrointestinal disease

(2018) Emma P. Halmos et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

IL-23 in inflammatory bowel diseases and colon cancer

(2018) Markus F. Neurath   CYTOKINE & GROWTH FACTOR REVIEWS

Treatment of Active Crohn’s Disease With an Ordinary Food-based Diet That Replicates Exclusive Enteral Nutrition

(2018) V. Svolos et al.   GASTROENTEROLOGY

Tight Junction in the Intestinal Epithelium: Its Association with Diseases and Regulation by Phytochemicals

(2018) Bonggi Lee et al.   Journal of Immunology Research

Saccharin induced liver inflammation in mice by altering the gut microbiota and its metabolic functions

(2017) Xiaoming Bian et al.   FOOD AND CHEMICAL TOXICOLOGY

A microbial signature for Crohn's disease

(2017) Victoria Pascal et al.   GUT

Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation

(2017) Benoit Chassaing et al.   GUT

Rutinosylated Ferulic Acid Attenuates Food Allergic Response and Colitis by Upregulating Regulatory T Cells in Mouse Models

(2017) Shigeru Katayama et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies

(2017) Siew C Ng et al.   LANCET

Carrageenan-induced colitis is associated with decreased population of anti-inflammatory bacterium, Akkermansia muciniphila , in the gut microbiota of C57BL/6J mice

(2017) Qingsen Shang et al.   TOXICOLOGY LETTERS

Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis

(2017) Lukas Bajer et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Effects of Probiotics, Prebiotics, and Synbiotics on Human Health

(2017) et al.   Nutrients

Effects of Low-Dose Non-Caloric Sweetener Consumption on Gut Microbiota in Mice

(2017) Takashi Uebanso et al.   Nutrients

Dietary ZnO nanoparticles alters intestinal microbiota and inflammation response in weaned piglets

(2017) Tian Xia et al.   Oncotarget

Gut Dysbiosis and Neurobehavioral Alterations in Rats Exposed to Silver Nanoparticles

(2017) Angela B. Javurek et al.   Scientific Reports

Zinc Oxide Nanoparticles Influence Microflora in Ileal Digesta and Correlate Well with Blood Metabolites

(2017) Yanni Feng et al.   Frontiers in Microbiology

Gut Microbiome Response to Sucralose and Its Potential Role in Inducing Liver Inflammation in Mice

(2017) Xiaoming Bian et al.   Frontiers in Physiology

The Impact of Western Diet and Nutrients on the Microbiota and Immune Response at Mucosal Interfaces

(2017) Donjete Statovci et al.   Frontiers in Immunology

Dynamics of the human gut microbiome in inflammatory bowel disease

(2017) Jonas Halfvarson et al.   Nature Microbiology

Sulfites inhibit the growth of four species of beneficial gut bacteria at concentrations regarded as safe for food

(2017) Sally V. Irwin et al.   PLoS One

Dietary Emulsifier–Induced Low-Grade Inflammation Promotes Colon Carcinogenesis

(2016) Emilie Viennois et al.   CANCER RESEARCH

How Sugar and Soft Drinks Are Related to Inflammatory Bowel Disease?

(2016) Xiaofa Qin   INFLAMMATORY BOWEL DISEASES

Intestinal stem cells and intestinal homeostasis in health and in inflammation: A review

(2016) Alexander L.A. Bloemendaal et al.   SURGERY

Caffeic acid ameliorates colitis in association with increased Akkermansia population in the gut microbiota of mice

(2016) Zhan Zhang et al.   Oncotarget

The influence of a short-term gluten-free diet on the human gut microbiome

(2016) Marc Jan Bonder et al.   Genome Medicine

The intestinal microbiome, barrier function, and immune system in inflammatory bowel disease: a tripartite pathophysiological circuit with implications for new therapeutic directions

(2016) Stephen M. Vindigni et al.   Therapeutic Advances in Gastroenterology

Review article: insights into colonic protein fermentation, its modulation and potential health implications

(2015) C. K. Yao et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Metal Oxide Nanoparticles Induce Minimal Phenotypic Changes in a Model Colon Gut Microbiota

(2015) Alicia A. Taylor et al.   ENVIRONMENTAL ENGINEERING SCIENCE

New developments in goblet cell mucus secretion and function

(2015) G M H Birchenough et al.   Mucosal Immunology

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

(2015) Benoit Chassaing et al.   NATURE

The global burden of IBD: from 2015 to 2025

(2015) Gilaad G. Kaplan   Nature Reviews Gastroenterology & Hepatology

Experimental colitis in mice is attenuated by topical administration of chlorogenic acid

(2015) Hubert Zatorski et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The Dietary Polysaccharide Maltodextrin Promotes Salmonella Survival and Mucosal Colonization in Mice

(2014) Kourtney P. Nickerson et al.   PLoS One

Low-Dose Aspartame Consumption Differentially Affects Gut Microbiota-Host Metabolic Interactions in the Diet-Induced Obese Rat

(2014) Marie S. A. Palmnäs et al.   PLoS One

Colonisation byFaecalibacterium prausnitziiand maintenance of clinical remission in patients with ulcerative colitis

(2013) E. Varela et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Flavonols enhanced production of anti-inflammatory substance(s) byBifidobacterium adolescentis: Prebiotic actions of galangin, quercetin, and fisetin

(2013) Kyuichi Kawabata et al.   BIOFACTORS

Minimal Intestinal Epithelial Cell Toxicity in Response to Short- and Long-Term Food-Relevant Inorganic Nanoparticle Exposure

(2013) Christie McCracken et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Role of “Western Diet” in Inflammatory Autoimmune Diseases

(2013) Arndt Manzel et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Western diet induces dysbiosis with increasedE coliin CEABAC10 mice,alters host barrier function favouring AIEC colonisation

(2013) Margarita Martinez-Medina et al.   GUT

Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis

(2013) Malin E V Johansson et al.   GUT

Aluminum enhances inflammation and decreases mucosal healing in experimental colitis in mice

(2013) G Pineton de Chambrun et al.   Mucosal Immunology

Host-Derived Nitrate Boosts Growth of E. coli in the Inflamed Gut

(2013) S. E. Winter et al.   SCIENCE

Metabolism of Anthocyanins by Human Gut Microflora and Their Influence on Gut Bacterial Growth

(2012) Maria Hidalgo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Aluminum as an adjuvant in Crohn’s disease induction

(2012) A Lerner   LUPUS

Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10 −/− mice

(2012) Suzanne Devkota et al.   NATURE

Crohn's Disease-Associated Adherent-Invasive Escherichia coli Adhesion Is Enhanced by Exposure to the Ubiquitous Dietary Polysaccharide Maltodextrin

(2012) Kourtney P. Nickerson et al.   PLoS One

Diet and risk of inflammatory bowel disease

(2011) Vibeke Andersen et al.   DIGESTIVE AND LIVER DISEASE

Protective effects of caffeic acid phenethyl ester (CAPE) on intestinal damage in necrotizing enterocolitis

(2011) Cuneyt Tayman et al.   PEDIATRIC SURGERY INTERNATIONAL

Inflammatory bowel disease: role of diet, microbiota, life style

(2011) Manuela G. Neuman et al.   Translational Research

Animal Protein Intake and Risk of Inflammatory Bowel Disease: The E3N Prospective Study

(2010) Prévost Jantchou et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Challenges associated with identifying the environmental determinants of the inflammatory bowel diseases

(2010) Natalie A. Molodecky et al.   INFLAMMATORY BOWEL DISEASES

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

(2010) Simon A. Hirota et al.   INFLAMMATORY BOWEL DISEASES

Role of flavonoids in intestinal tight junction regulation

(2010) Takuya Suzuki et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Diet, gut microbiota and immune responses

(2010) Kendle M Maslowski et al.   NATURE IMMUNOLOGY

Pre-illness changes in dietary habits and diet as a risk factor for inflammatory bowel disease: A case-control study

(2010) Giovanni Maconi   WORLD JOURNAL OF GASTROENTEROLOGY

Carbohydrate maldigestion induces necrotizing enterocolitis in preterm pigs

(2009) Thomas Thymann et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Effects of a gluten-free diet on gut microbiota and immune function in healthy adult human subjects

(2009) Giada De Palma et al.   BRITISH JOURNAL OF NUTRITION

Toxicity and cellular responses of intestinal cells exposed to titanium dioxide

(2009) Brian A. Koeneman et al.   CELL BIOLOGY AND TOXICOLOGY

Mucosal bacterial microflora and mucus layer thickness inadolescents with inflammatory bowel disease

(2009) Krzysztof Fyderek et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The NLR Gene Family: A Standard Nomenclature

(2008) Jenny P.-Y. Ting et al.   IMMUNITY

Bacterial Overgrowth and Inflammation of Small Intestine After Carboxymethylcellulose Ingestion in Genetically Susceptible Mice

(2008) Alexander Swidsinski et al.   INFLAMMATORY BOWEL DISEASES

The potential influence of fruit polyphenols on colonic microflora and human gut health

(2008) Shanthi G. Parkar et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

(2008) H. Sokol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA