Glycolysis Rate-Limiting Enzymes: Novel Potential Regulators of Rheumatoid Arthritis Pathogenesis

Inhibition of PFKFB3 induces cell death and synergistically enhances chemosensitivity in endometrial cancer

(2021) Yinan Xiao et al.   ONCOGENE

Rheumatoid arthritis CD14 + monocytes display metabolic and inflammatory dysfunction, a phenotype that precedes clinical manifestation of disease

(2021) Trudy McGarry et al.   Clinical & Translational Immunology

Grap2 cyclin D interacting protein negatively regulates CREB‑binding protein, inhibiting fibroblast‑like synoviocyte growth

(2021) Hidetoshi Fujita et al.   Molecular Medicine Reports

Reactive Oxygen Species in Autoimmune Cells: Function, Differentiation, and Metabolism

(2021) Weiji Lin et al.   Frontiers in Immunology

Role of PFKFB3 and PFKFB4 in Cancer: Genetic Basis, Impact on Disease Development/Progression, and Potential as Therapeutic Targets

(2021) Krzysztof Kotowski et al.   Cancers

Effects of the Novel PFKFB3 Inhibitor KAN0438757 on Colorectal Cancer Cells and Its Systemic Toxicity Evaluation In Vivo

(2021) Tiago De Oliveira et al.   Cancers

The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts

(2021) Jasna Friščić et al.   IMMUNITY

Pyruvate Kinase M2 Contributes to TLR-Mediated Inflammation and Autoimmunity by Promoting Pyk2 Activation

(2021) Xin Zhang et al.   Frontiers in Immunology

Metabolic Control of Autoimmunity and Tissue Inflammation in Rheumatoid Arthritis

(2021) Jingtao Qiu et al.   Frontiers in Immunology

Metabolic changes in synovial cells in early inflammation: Involvement of CREB phosphorylation in the anti-inflammatory effect of 2-deoxyglucose

(2021) Kenji Kishimoto et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Discovery and development of tumor glycolysis rate-limiting enzyme inhibitors

(2021) Xueyan Sun et al.   BIOORGANIC CHEMISTRY

The PFKFB3 Inhibitor AZ67 Inhibits Angiogenesis Independently of Glycolysis Inhibition

(2021) Besa Emini Veseli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2-Deoxy-D-glucose Alleviates Collagen-Induced Arthritis of Rats and Is Accompanied by Metabolic Regulation of the Spleen and Liver

(2021) Hongxing Wang et al.   Frontiers in Immunology

Glycolysis Inhibition Induces Functional and Metabolic Exhaustion of CD4+ T Cells in Type 1 Diabetes

(2021) Christina P. Martins et al.   Frontiers in Immunology

Inhibition of glycolysis in the presence of antigen generates suppressive antigen-specific responses and restrains rheumatoid arthritis in mice

(2021) Joslyn L. Mangal et al.   BIOMATERIALS

Targeting immunometabolism as an anti-inflammatory strategy

(2020) Eva M. Pålsson-McDermott et al.   CELL RESEARCH

Metabolic pathways mediate pathogenesis and offer targets for treatment in rheumatic diseases

(2020) Brandon Wyman et al.   CURRENT OPINION IN RHEUMATOLOGY

Immunometabolism in the development of rheumatoid arthritis

(2020) Cornelia M. Weyand et al.   IMMUNOLOGICAL REVIEWS

Targeting bioenergetics prevents CD4 T cell–mediated activation of synovial fibroblasts in rheumatoid arthritis

(2020) Andreea Petrasca et al.   RHEUMATOLOGY

Glucose transporter 1 in rheumatoid arthritis and autoimmunity

(2020) Ekaterina Zezina et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Hexokinase 2 Depletion Confers Sensitization to Metformin and Inhibits Glycolysis in Lung Squamous Cell Carcinoma

(2020) Wenzheng Guo et al.   Frontiers in Oncology

3PO as a Selective Inhibitor of 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3 in A375 Human Melanoma Cells

(2020) KRZYSZTOF KOTOWSKI et al.   ANTICANCER RESEARCH

SUMOylation in development and neurodegeneration

(2020) Tak-Yu Yau et al.   DEVELOPMENT

Inhibition of glycolysis ameliorate arthritis in adjuvant arthritis rats by inhibiting synoviocyte activation through AMPK/NF-кB pathway

(2020) Ying Wang et al.   INFLAMMATION RESEARCH

PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells

(2020) Selahattin C. Ozcan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Restoring synovial homeostasis in rheumatoid arthritis by targeting fibroblast-like synoviocytes

(2020) Gyrid Nygaard et al.   Nature Reviews Rheumatology

Glycogen metabolism regulates macrophage-mediated acute inflammatory responses

(2020) Jingwei Ma et al.   Nature Communications

Mst1 promotes mitochondrial dysfunction and apoptosis in oxidative stress-induced rheumatoid arthritis synoviocytes

(2020) Yingjie Wang et al.   Aging-US

Identification of Gliotoxin isolated from marine fungus as a new pyruvate kinase M2 inhibitor

(2020) Wei Tang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

3-Bromopyruvate regulates the status of glycolysis and BCNU sensitivity in human hepatocellular carcinoma cells

(2020) Xiaodong Sun et al.   BIOCHEMICAL PHARMACOLOGY

Rheumatoid arthritis synovial microenvironment induces metabolic and functional adaptations in dendritic cells

(2020) M. Canavan et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Small molecule 3PO inhibits glycolysis but does not bind to 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase‐3 (PFKFB3)

(2020) Besa Emini Veseli et al.   FEBS LETTERS

Metabolic reprogramming as a key regulator in the pathogenesis of rheumatoid arthritis

(2020) Wei-wei Cai et al.   INFLAMMATION RESEARCH

Upregulated PKM2 in Macrophages Exacerbates Experimental Arthritis via STAT1 Signaling

(2020) Jing Xu et al.   JOURNAL OF IMMUNOLOGY

Proinflammatory profile of autoimmune CD8 + T cells relies on increased LDHA activity and aerobic glycolysis

(2020) M. Margarida Souto‐Carneiro et al.   Arthritis & Rheumatology

Hypoxia-Inducible Factor Is Critical for Pathogenesis and Regulation of Immune Cell Functions in Rheumatoid Arthritis

(2020) Xin Guo et al.   Frontiers in Immunology

PFKFB3 inhibitors as potential anticancer agents: Mechanisms of action, current developments, and structure-activity relationships

(2020) Yinhu Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Methrotexate Treatment Inmunomodulates Abnormal Cytokine Expression by T CD4 Lymphocytes Present in DMARD-Naïve Rheumatoid Arthritis Patients

(2020) Jorge Monserrat Sanz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Osteoclast differentiation by RANKL and OPG signaling pathways

(2020) Nobuyuki Udagawa et al.   JOURNAL OF BONE AND MINERAL METABOLISM

3-Bromopyruvate ameliorates pulmonary arterial hypertension by improving mitochondrial metabolism

(2020) Yuan Guo et al.   LIFE SCIENCES

Disease-Specific Autoantibodies Induce Trained Immunity in RA Synovial Tissues and Its Gene Signature Correlates with the Response to Clinical Therapy

(2020) Xiaoli Dai et al.   MEDIATORS OF INFLAMMATION

B cells polarize pathogenic inflammatory T helper subsets through ICOSL-dependent glycolysis

(2020) Qiu-Hui Zeng et al.   Science Advances

Increased SUMO-activating enzyme SAE1/UBA2 promotes glycolysis and pathogenic behavior of rheumatoid fibroblast-like synoviocytes

(2020) Cuicui Wang et al.   JCI Insight

Cellular toxicity of the metabolic inhibitor 2-deoxyglucose and associated resistance mechanisms

(2020) Clotilde Laussel et al.   BIOCHEMICAL PHARMACOLOGY

Reprogramming of synovial macrophage metabolism by synovial fibroblasts under inflammatory conditions

(2020) Noritaka Saeki et al.   Cell Communication and Signaling

Role of glucose metabolism in aggressive phenotype of fibroblast-like synoviocytes: Latest evidence and therapeutic approaches in rheumatoid arthritis

(2020) Maryam Masoumi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Revisiting the Warburg effect: historical dogma versus current understanding

(2020) Peter Vaupel et al.   JOURNAL OF PHYSIOLOGY-LONDON

The immunology of rheumatoid arthritis

(2020) Cornelia M. Weyand et al.   NATURE IMMUNOLOGY

Dopamine suppresses osteoclast differentiation via cAMP/PKA/CREB pathway

(2020) Lufei Wang et al.   CELLULAR SIGNALLING

Tofacitinib for the treatment of rheumatoid arthritis: an update

(2019) Kunihiro Yamaoka   Expert Review of Clinical Immunology

Unappreciated Role of LDHA and LDHB to Control Apoptosis and Autophagy in Tumor Cells

(2019) Kaja Urbańska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The role of protein SUMOylation in rheumatoid arthritis

(2019) Sajad Dehnavi et al.   JOURNAL OF AUTOIMMUNITY

B7-H3 promotes aerobic glycolysis and chemoresistance in colorectal cancer cells by regulating HK2

(2019) Tongguo Shi et al.   Cell Death & Disease

Emerging roles of aerobic glycolysis in breast cancer

(2019) Z. Wu et al.   Clinical & Translational Oncology

Immunometabolism: an overview and therapeutic prospects in autoimmune diseases

(2019) Chrysoula Stathopoulou et al.   Immunotherapy

An Overview of Structure, Function and Regulation of Pyruvate Kinases

(2019) Norbert Schormann et al.   PROTEIN SCIENCE

The Warburg Effect, Lactate, and Nearly a Century of Trying to Cure Cancer

(2019) Netanya Y. Spencer et al.   SEMINARS IN NEPHROLOGY

FcγR-TLR Cross-Talk Enhances TNF Production by Human Monocyte-Derived DCs via IRF5-Dependent Gene Transcription and Glycolytic Reprogramming

(2019) Willianne Hoepel et al.   Frontiers in Immunology

Daurinol Attenuates Autoimmune Arthritis via Stabilization of Nrp1–PTEN–Foxp3 Signaling in Regulatory T Cells

(2019) Min-Jung Park et al.   Frontiers in Immunology

Hexokinase 2 Regulates Ovarian Cancer Cell Migration, Invasion and Stemness via FAK/ERK1/2/MMP9/NANOG/SOX9 Signaling Cascades

(2019) Michelle K. Y. Siu et al.   Cancers

Costunolide reduces glycolysis-associated activation of hepatic stellate cells via inhibition of hexokinase-2

(2019) Dujing Ban et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Pharmacological properties and derivatives of shikonin—A review in recent years

(2019) Chuanjie Guo et al.   PHARMACOLOGICAL RESEARCH

Ablation of endothelial Pfkfb3 protects mice from acute lung injury in LPS-induced endotoxemia

(2019) Lina Wang et al.   PHARMACOLOGICAL RESEARCH

STAT3 Mediates the Differential Effects of Oncostatin M and TNFα on RA Synovial Fibroblast and Endothelial Cell Function

(2019) Megan M. Hanlon et al.   Frontiers in Immunology

Pyruvate kinase M2: A simple molecule with complex functions

(2019) Mohammed Alquraishi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Benserazide is a novel inhibitor targeting PKM2 for melanoma treatment

(2019) Youyou Zhou et al.   INTERNATIONAL JOURNAL OF CANCER

Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring

(2019) Valentina Pucino et al.   Cell Metabolism

2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents

(2019) B. Pajak et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

GRK2 Mediated Abnormal Transduction of PGE2-EP4-cAMP-CREB Signaling Induces the Imbalance of Macrophages Polarization in Collagen-Induced Arthritis Mice

(2019) Xuezhi Yang et al.   Cells

NADPH ameliorates MPTP-induced dopaminergic neurodegeneration through inhibiting p38MAPK activation

(2018) Jing-si Zhou et al.   ACTA PHARMACOLOGICA SINICA

Vimentin as antigenic target in autoimmunity: A comprehensive review

(2018) Aram Musaelyan et al.   AUTOIMMUNITY REVIEWS

Oxidative stress, consequences and ROS mediated cellular signaling in rheumatoid arthritis

(2018) Abdul-Rehman Phull et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4+T Cells in Patients With Type 1 Diabetes

(2018) Meghan L. Marre et al.   DIABETES

Pyruvate Kinase M2 Modulates the Glycolysis of Chondrocyte and Extracellular Matrix in Osteoarthritis

(2018) Xiaobo Yang et al.   DNA AND CELL BIOLOGY

DNA damage, metabolism and aging in pro-inflammatory T cells

(2018) Yinyin Li et al.   EXPERIMENTAL GERONTOLOGY

Redox-sensitive signaling in inflammatory T cells and in autoimmune disease

(2018) Cornelia M. Weyand et al.   FREE RADICAL BIOLOGY AND MEDICINE

Stattic inhibits RANKL-mediated osteoclastogenesis by suppressing activation of STAT3 and NF-κB pathways

(2018) Chang-hong Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

PFK15, a PFKFB3 antagonist, inhibits autophagy and proliferation in rhabdomyosarcoma cells

(2018) Chunhui Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

IgG Immunocomplexes Sensitize Human Monocytes for Inflammatory Hyperactivity via Transcriptomic and Epigenetic Reprogramming in Rheumatoid Arthritis

(2018) Qiao Zhong et al.   JOURNAL OF IMMUNOLOGY

ICOS Signaling Controls Induction and Maintenance of Collagen-Induced Arthritis

(2018) Vincent Panneton et al.   JOURNAL OF IMMUNOLOGY

Increased hyperpolarized [1-13 C] lactate production in a model of joint inflammation is not accompanied by tissue acidosis as assessed using hyperpolarized 13 C-labelled bicarbonate

(2018) Alan J. Wright et al.   NMR IN BIOMEDICINE

Metabolism as a Target for Modulation in Autoimmune Diseases

(2018) Nick Huang et al.   TRENDS IN IMMUNOLOGY

Small ubiquitin-like modifier 1 modification of pyruvate kinase M2 promotes aerobic glycolysis and cell proliferation in A549 human lung cancer cells

(2018) Shuxian An et al.   OncoTargets and Therapy

JAK-STAT blockade alters synovial bioenergetics, mitochondrial function and pro-inflammatory mediators in Rheumatoid arthritis

(2018) Trudy McGarry et al.   Arthritis & Rheumatology

The Potential Role of Trained Immunity in Autoimmune and Autoinflammatory Disorders

(2018) Rob J. W. Arts et al.   Frontiers in Immunology

Four Key Steps Control Glycolytic Flux in Mammalian Cells

(2018) Lukas Bahati Tanner et al.   Cell Systems

Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis

(2018) Marta F Bustamante et al.   ANNALS OF THE RHEUMATIC DISEASES

Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination

(2018) Nina M. S. Gustafsson et al.   Nature Communications

Shikonin Inhibits Tumor Growth in Mice by Suppressing Pyruvate Kinase M2-mediated Aerobic Glycolysis

(2018) Xiaoyue Zhao et al.   Scientific Reports

Inhibition of Glycolysis Reduces Disease Severity in an Autoimmune Model of Rheumatoid Arthritis

(2018) Georges Abboud et al.   Frontiers in Immunology

Fructose 2,6-Bisphosphate in Cancer Cell Metabolism

(2018) Ramon Bartrons et al.   Frontiers in Oncology

Cellular Metabolism in Lung Health and Disease

(2018) Gang Liu et al.   Annual Review of Physiology

Altered metabolic pathways regulate synovial inflammation in rheumatoid arthritis

(2018) U. Fearon et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Cell metabolism as a potentially targetable pathway in RA

(2018) Trudy McGarry et al.   Nature Reviews Rheumatology

6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 and 4: A pair of valves for fine-tuning of glucose metabolism in human cancer

(2018) Mei Yi et al.   Molecular Metabolism

TGF-β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells

(2017) Ana Rodríguez-García et al.   FEBS Journal

Metabolomics analysis of Danggui Sini decoction on treatment of collagen-induced arthritis in rats

(2017) Bang Cheng et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Benserazide, a dopadecarboxylase inhibitor, suppresses tumor growth by targeting hexokinase 2

(2017) Wei Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Immunometabolism in early and late stages of rheumatoid arthritis

(2017) Cornelia M. Weyand et al.   Nature Reviews Rheumatology

3-Bromopyruvate as a potential pharmaceutical in the light of experimental data

(2017) Izabela Szczuka et al.   Postepy Higieny I Medycyny Doswiadczalnej

Ras Signaling Inhibitors Attenuate Disease in Adjuvant-Induced Arthritis via Targeting Pathogenic Antigen-Specific Th17-Type Cells

(2017) Morad Zayoud et al.   Frontiers in Immunology

Resolution of TLR2-induced inflammation through manipulation of metabolic pathways in Rheumatoid Arthritis

(2017) Trudy McGarry et al.   Scientific Reports

Glucose-6-Phosphate Isomerase (G6PI) Mediates Hypoxia-Induced Angiogenesis in Rheumatoid Arthritis

(2017) Ying Lu et al.   Scientific Reports

3-bromopyruvate ameliorate autoimmune arthritis by modulating Th17/Treg cell differentiation and suppressing dendritic cell activation

(2017) Takaichi Okano et al.   Scientific Reports

Hif-1α Knockdown Reduces Glycolytic Metabolism and Induces Cell Death of Human Synovial Fibroblasts Under Normoxic Conditions

(2017) Manuel J. Del Rey et al.   Scientific Reports

Dysregulated bioenergetics: a key regulator of joint inflammation

(2016) M Biniecka et al.   ANNALS OF THE RHEUMATIC DISEASES

Lactate at the crossroads of metabolism, inflammation, and autoimmunity

(2016) Valentina Pucino et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Exploration of the serum metabolite signature in patients with rheumatoid arthritis using gas chromatography–mass spectrometry

(2016) Jia Zhou et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Rheumatoid arthritis

(2016) Josef S Smolen et al.   LANCET

Could glucose metabolism be a sweet target for RA therapy?

(2016) Sarah Onuora   Nature Reviews Rheumatology

Hypoxia, mitochondrial dysfunction and synovial invasiveness in rheumatoid arthritis

(2016) Ursula Fearon et al.   Nature Reviews Rheumatology

Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism

(2016) M. Peng et al.   SCIENCE

Restoring oxidant signaling suppresses proarthritogenic T cell effector functions in rheumatoid arthritis

(2016) Zhen Yang et al.   Science Translational Medicine

PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation

(2016) Min Xie et al.   Nature Communications

Critical Role of Glucose Metabolism in Rheumatoid Arthritis Fibroblast-like Synoviocytes

(2016) Ricard Garcia-Carbonell et al.   Arthritis & Rheumatology

HK2/hexokinase-II integrates glycolysis and autophagy to confer cellular protection

(2015) Valerie P Tan et al.   Autophagy

Autophagy in autoimmune disease

(2015) Zhen Yang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The glycolytic enzyme PFKFB3/phosphofructokinase regulates autophagy

(2014) Zhen Yang et al.   Autophagy

Daurinol, a catalytic inhibitor of topoisomerase IIα, suppresses SNU-840 ovarian cancer cell proliferation through cell cycle arrest in S phase

(2014) KYUNGSU KANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Targets of Immune Regeneration in Rheumatoid Arthritis

(2014) Philipp J. Hohensinner et al.   MAYO CLINIC PROCEEDINGS

How do glycolytic enzymes favour cancer cell proliferation by nonmetabolic functions?

(2014) H Lincet et al.   ONCOGENE

PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis

(2014) Liangchun Yang et al.   Nature Communications

Adapting glycolysis to cancer cell proliferation: the MAPK pathway focuses on PFKFB3: Figure 1

(2013) Juan P. Bolaños   BIOCHEMICAL JOURNAL

Direct inhibition of hexokinase activity by metformin at least partially impairs glucose metabolism and tumor growth in experimental breast cancer

(2013) Cecilia Marini et al.   CELL CYCLE

Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells

(2013) Zhen Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Oxidation Degradation of Rhodamine B in Aqueous byUV/S2O8 2−Treatment System

(2012) Xiaoyang Chen et al.   INTERNATIONAL JOURNAL OF PHOTOENERGY

K-RAS GTPase- and B-RAF kinase-mediated T-cell tolerance defects in rheumatoid arthritis

(2012) K. Singh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Energy metabolism and rheumatic diseases: from cell to organism

(2012) Cornelia M Spies et al.   ARTHRITIS RESEARCH & THERAPY

Oncostatin M promotes STAT3 activation, VEGF production, and invasion in osteosarcoma cell lines

(2011) Stacey L Fossey et al.   BMC CANCER

Glycolysis and rheumatoid arthritis

(2011) Xiaotian CHANG et al.   International Journal of Rheumatic Diseases

Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2

(2011) J Chen et al.   ONCOGENE

The tumour-associated glycoprotein podoplanin is expressed in fibroblast-like synoviocytes of the hyperplastic synovial lining layer in rheumatoid arthritis

(2011) Anna-Karin H Ekwall et al.   ARTHRITIS RESEARCH & THERAPY

Silencing the Expression of Ras Family GTPase Homologues Decreases Inflammation and Joint Destruction in Experimental Arthritis

(2010) Daphne de Launay et al.   AMERICAN JOURNAL OF PATHOLOGY

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Particular association of clinical and genetic features with autoimmunity to citrullinated α-enolase in rheumatoid arthritis

(2010) Ariana Montes et al.   ARTHRITIS AND RHEUMATISM

Identification of Proteins with Increased Expression in Rheumatoid Arthritis Synovial Tissues

(2009) X. CHANG et al.   JOURNAL OF RHEUMATOLOGY

Characterization of synovial tissue from arthritis patients: a proton magnetic resonance spectroscopic investigation

(2009) Carol A. Hitchon et al.   RHEUMATOLOGY INTERNATIONAL