NADPH ameliorates MPTP-induced dopaminergic neurodegeneration through inhibiting p38MAPK activation

Combined NADPH and the NOX inhibitor apocynin provides greater anti-inflammatory and neuroprotective effects in a mouse model of stroke

(2017) Yuan-Yuan Qin et al.   FREE RADICAL BIOLOGY AND MEDICINE

What has passed is prolog: new cellular and physiological roles of G6PD

(2016) Hung-Chi Yang et al.   FREE RADICAL RESEARCH

TRPM2 Promotes Neurotoxin MPP+/MPTP-Induced Cell Death

(2016) Yuyang Sun et al.   MOLECULAR NEUROBIOLOGY

Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders

(2016) Md. Torequl Islam   NEUROLOGICAL RESEARCH

β-Ecdysterone Protects SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Apoptosis via Mitochondria-Dependent Mechanism: Involvement of p38MAPK–p53 Signaling Pathway

(2016) Zhi Pan et al.   NEUROTOXICITY RESEARCH

Nephroprotective Effects of N-Acetylcysteine Amide against Contrast-Induced Nephropathy through Upregulating Thioredoxin-1, Inhibiting ASK1/p38MAPK Pathway, and Suppressing Oxidative Stress and Apoptosis in Rats

(2016) Xuezhong Gong et al.   Oxidative Medicine and Cellular Longevity

N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson's Disease: Preliminary Clinical and Cell Line Data

(2016) Daniel A. Monti et al.   PLoS One

Compromised MAPK signaling in human diseases: an update

(2015) Eun Kyung Kim et al.   ARCHIVES OF TOXICOLOGY

Controlled Striatal DOPA Production From a Gene Delivery System in a Rodent Model of Parkinson's Disease

(2015) Erik Cederfjäll et al.   MOLECULAR THERAPY

Ischemia/reperfusion-induced upregulation of TIGAR in brain is mediated by SP1 and modulated by ROS and hormones involved in glucose metabolism

(2015) Meiling Sun et al.   NEUROCHEMISTRY INTERNATIONAL

Pathogenic Mechanisms of Neurodegeneration in Parkinson Disease

(2015) Stephen Mullin et al.   NEUROLOGIC CLINICS

Reduced Nicotinamide Adenine Dinucleotide Phosphate, a Pentose Phosphate Pathway Product, Might Be a Novel Drug Candidate for Ischemic Stroke

(2015) Mei Li et al.   STROKE

Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease

(2015) Brent J. Ryan et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Role of Oxidative Stress in Neurodegenerative Diseases

(2015) Geon Ha Kim et al.   Experimental Neurobiology

The role of malic enzyme as the provider of NADPH in oleaginous microorganisms: a reappraisal and unsolved problems

(2014) Colin Ratledge   BIOTECHNOLOGY LETTERS

A TIGAR-Regulated Metabolic Pathway Is Critical for Protection of Brain Ischemia

(2014) M. Li et al.   JOURNAL OF NEUROSCIENCE

Protective Effects of Salidroside in the MPTP/MPP+-Induced Model of Parkinson's Disease through ROS–NO-Related Mitochondrion Pathway

(2014) Songhai Wang et al.   MOLECULAR NEUROBIOLOGY

Drug-induced parkinsonism

(2013) José López-Sendón et al.   Expert Opinion On Drug Safety

TNFR1/TNF-α and mitochondria interrelated signaling pathway mediates quinocetone-induced apoptosis in HepG2 cells

(2013) Chaoming Zhang et al.   FOOD AND CHEMICAL TOXICOLOGY

Glutathione metabolism and Parkinson's disease

(2013) Michelle Smeyne et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lysosomal dysfunction in Parkinson disease

(2012) Benjamin Dehay et al.   Autophagy

Pyridine Nucleotide Regulation of Cardiac Intermediary Metabolism

(2012) John R. Ussher et al.   CIRCULATION RESEARCH

Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

(2012) David N. Hauser et al.   NEUROBIOLOGY OF DISEASE

Kinases and kinase signaling pathways: Potential therapeutic targets in Parkinson's disease

(2012) Gang Wang et al.   PROGRESS IN NEUROBIOLOGY

Mitochondria and Programmed Cell Death in Parkinson's Disease: Apoptosis and Beyond

(2011) Celine Perier et al.   ANTIOXIDANTS & REDOX SIGNALING

Neuroprotective cytokines repress PUMA induction in the 1-methyl-4-phenylpyridinium (MPP+) model of Parkinson’s disease

(2011) Yeon-Hee Kook et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Novel Role for Interleukin-27 (IL-27) as Mediator of Intestinal Epithelial Barrier Protection Mediated via Differential Signal Transducer and Activator of Transcription (STAT) Protein Signaling and Induction of Antibacterial and Anti-inflammatory Proteins

(2011) Julia Diegelmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Motor complications in Parkinson's disease: Ten year follow-up study

(2010) Iria Cabo López et al.   MOVEMENT DISORDERS

Impaired glutamate homeostasis and programmed cell death in a chronic MPTP mouse model of Parkinson's disease

(2009) G.E. Meredith et al.   EXPERIMENTAL NEUROLOGY

Decreased inflammation and augmented expression of trophic factors correlate with MOG-induced neuroprotection of the injured nigrostriatal system in the murine MPTP model of Parkinson's disease

(2009) I. Kurkowska-Jastrzębska et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mitochondrial kinases in Parkinson’s disease: Converging insights from neurotoxin and genetic models

(2009) Ruben K. Dagda et al.   MITOCHONDRION

Parkinson disease and impulse control disorders: a review of clinical features, pathophysiology and management

(2009) K Wu et al.   POSTGRADUATE MEDICAL JOURNAL

The PINK1–Parkin pathway is involved in the regulation of mitochondrial remodeling process

(2008) Jeehye Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glutathione and Parkinson's disease: Is this the elephant in the room?

(2008) Gail D. Zeevalk et al.   BIOMEDICINE & PHARMACOTHERAPY

Selective Activation of p38 Mitogen-Activated Protein Kinase in Dopaminergic Neurons of Substantia Nigra Leads to Nuclear Translocation of p53 in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Mice

(2008) S. Karunakaran et al.   JOURNAL OF NEUROSCIENCE