Hif-1α Knockdown Reduces Glycolytic Metabolism and Induces Cell Death of Human Synovial Fibroblasts Under Normoxic Conditions
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Hif-1α Knockdown Reduces Glycolytic Metabolism and Induces Cell Death of Human Synovial Fibroblasts Under Normoxic Conditions
Authors
Keywords
-
Journal
Scientific Reports
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-06-10
DOI
10.1038/s41598-017-03921-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Critical Role of Glucose Metabolism in Rheumatoid Arthritis Fibroblast-like Synoviocytes
- (2016) Ricard Garcia-Carbonell et al. Arthritis & Rheumatology
- Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
- (2015) Eva M. Palsson-McDermott et al. Cell Metabolism
- Reshaping of Human Macrophage Polarization through Modulation of Glucose Catabolic Pathways
- (2015) Elena Izquierdo et al. JOURNAL OF IMMUNOLOGY
- Hypoxia and STAT3 signalling interactions regulate pro-inflammatory pathways in rheumatoid arthritis
- (2014) Wei Gao et al. ANNALS OF THE RHEUMATIC DISEASES
- Inhibition of Hypoxia Inducible Factor 1α by siRNA-Induced Apoptosis in Human Retinoblastoma Cells
- (2014) Yu Gao et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation
- (2014) Valerie A. Gerriets et al. JOURNAL OF CLINICAL INVESTIGATION
- mTORC1-Dependent Metabolic Reprogramming Is a Prerequisite for NK Cell Effector Function
- (2014) Raymond P. Donnelly et al. JOURNAL OF IMMUNOLOGY
- mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity
- (2014) S.-C. Cheng et al. SCIENCE
- A pharmacoproteomic study confirms the synergistic effect of chondroitin sulfate and glucosamine
- (2014) Valentina Calamia et al. Scientific Reports
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- Notch-1 mediates hypoxia-induced angiogenesis in rheumatoid arthritis
- (2012) Wei Gao et al. ARTHRITIS AND RHEUMATISM
- AMPK and GCN2–ATF4 signal the repression of mitochondria in colon cancer cells
- (2012) Inmaculada Martínez-Reyes et al. BIOCHEMICAL JOURNAL
- Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay
- (2012) T. Fiaschi et al. CANCER RESEARCH
- Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
- (2012) Gregg L. Semenza TRENDS IN PHARMACOLOGICAL SCIENCES
- Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells
- (2011) Yasuki Higashimura et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells
- (2011) Lewis Z. Shi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The transcriptional response of normal and rheumatoid arthritis synovial fibroblasts to hypoxia
- (2010) Manuel J. Del Rey et al. ARTHRITIS AND RHEUMATISM
- The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
- (2010) Tugba Simsek et al. Cell Stem Cell
- Up-regulation of the ATPase Inhibitory Factor 1 (IF1) of the Mitochondrial H+-ATP Synthase in Human Tumors Mediates the Metabolic Shift of Cancer Cells to a Warburg Phenotype
- (2010) Laura Sánchez-Cenizo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation
- (2010) J.-C. Rodriguez-Prados et al. JOURNAL OF IMMUNOLOGY
- Quiescent Fibroblasts Exhibit High Metabolic Activity
- (2010) Johanna M. S. Lemons et al. PLOS BIOLOGY
- Human inflammatory synovial fibroblasts induce enhanced myeloid cell recruitment and angiogenesis through a hypoxia-inducible transcription factor 1α/vascular endothelial growth factor-mediated pathway in immunodeficient mice
- (2009) Manuel J. del Rey et al. ARTHRITIS AND RHEUMATISM
- The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
- (2008) Ralph J. DeBerardinis et al. Cell Metabolism
- Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c
- (2008) Allyson E. Vaughn et al. NATURE CELL BIOLOGY
- Role of hypoxia-inducible factor-1 in hypoxia-induced expressions of IL-8, MMP-1 and MMP-3 in rheumatoid fibroblast-like synoviocytes
- (2008) J. K. Ahn et al. RHEUMATOLOGY
- Human Skin Keloid Fibroblasts Display Bioenergetics of Cancer Cells
- (2007) Annette S. Vincent et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now