Methrotexate Treatment Inmunomodulates Abnormal Cytokine Expression by T CD4 Lymphocytes Present in DMARD-Naïve Rheumatoid Arthritis Patients

The Abnormal CD4+T Lymphocyte Subset Distribution and Vbeta Repertoire in New-onset Rheumatoid Arthritis Can Be Modulated by Methotrexate Treament

(2019) Jorge Monserrat et al.   Cells

The Plasticity of Th17 Cells in the Pathogenesis of Rheumatoid Arthritis

(2017) Shigeru Kotake et al.   Journal of Clinical Medicine

Ratio of Circulating IFNγ+“Th17 Cells” in Memory Th Cells Is Inversely Correlated with the Titer of Anti-CCP Antibodies in Early-Onset Rheumatoid Arthritis Patients Based on Flow Cytometry Methods of the Human Immunology Project

(2016) Shigeru Kotake et al.   Biomed Research International

STAT6 and STAT1 Pathway Activation in Circulating Lymphocytes and Monocytes as Predictor of Treatment Response in Rheumatoid Arthritis

(2016) Krista Kuuliala et al.   PLoS One

Relationship of CD146 expression to secretion of interleukin (IL)-17, IL-22 and interferon-γ by CD4+T cells in patients with inflammatory arthritis

(2015) C. Wu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Regulation of human helper T cell subset differentiation by cytokines

(2015) Nathalie Schmitt et al.   CURRENT OPINION IN IMMUNOLOGY

The number of circulating monocytes as biomarkers of the clinical response to methotrexate in untreated patients with rheumatoid arthritis

(2015) Luis Chara et al.   Journal of Translational Medicine

Constitutive STAT3 Phosphorylation in Circulating CD4+ T Lymphocytes Associates with Disease Activity and Treatment Response in Recent-Onset Rheumatoid Arthritis

(2015) Krista Kuuliala et al.   PLoS One

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update

(2013) Josef S Smolen et al.   ANNALS OF THE RHEUMATIC DISEASES

From a gene-centric to whole-proteome view of differentiation of T helper cell subsets

(2013) T. Lonnberg et al.   Briefings in Functional Genomics

Patients with the most advanced rheumatoid arthritis remain with Th1 systemic defects after TNF inhibitors treatment despite clinical improvement

(2013) Agata Kosmaczewska et al.   RHEUMATOLOGY INTERNATIONAL

The many faces of CD4 T cells: Roles in immunity and disease

(2013) Federica Sallusto et al.   SEMINARS IN IMMUNOLOGY

STATs Shape the Active Enhancer Landscape of T Cell Populations

(2012) Golnaz Vahedi et al.   CELL

T cells out of control—impaired immune regulation in the inflamed joint

(2012) Ellen J. Wehrens et al.   Nature Reviews Rheumatology

Frequency of Th17 CD4+ T Cells in Early Rheumatoid Arthritis: A Marker of Anti-CCP Seropositivity

(2012) Irene Arroyo-Villa et al.   PLoS One

The CD14bright CD16+ monocyte subset is expanded in rheumatoid arthritis and promotes expansion of the Th17 cell population

(2011) Manuela Rossol et al.   ARTHRITIS AND RHEUMATISM

CD4+ memory T cell survival

(2011) Justin J Taylor et al.   CURRENT OPINION IN IMMUNOLOGY

The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent manner

(2010) Kevin D. Deane et al.   ARTHRITIS AND RHEUMATISM

Up-regulation of cytokines and chemokines predates the onset of rheumatoid arthritis

(2010) Heidi Kokkonen et al.   ARTHRITIS AND RHEUMATISM

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

Rheumatoid arthritis

(2010) David L Scott et al.   LANCET

The Current STATus of lymphocyte signaling: new roles for old players

(2009) Adewole S Adamson et al.   CURRENT OPINION IN IMMUNOLOGY

Heterogeneity of CD4+ memory T cells: Functional modules for tailored immunity

(2009) Federica Sallusto et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Phenotypic classification of human CD4+ T cell subsets and their differentiation

(2008) R. Okada et al.   INTERNATIONAL IMMUNOLOGY

Human interleukin 17–producing cells originate from a CD161+CD4+T cell precursor

(2008) Lorenzo Cosmi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T cells in rheumatoid arthritis

(2008) Andrew P Cope   ARTHRITIS RESEARCH & THERAPY