Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

Pseudomonas aeruginosa OprF plays a role in resistance to macrophage clearance during acute infection

(2021) Malika Moussouni et al.   Scientific Reports

Phenotypic and Genotypic Adaptations in Pseudomonas aeruginosa Biofilms following Long-Term Exposure to an Alginate Oligomer Therapy

(2021) Juliette L. Oakley et al.   mSphere

Hypermutator Pseudomonas aeruginosa exploits multiple genetic pathways to develop multidrug resistance during long-term infections in the airways of cystic fibrosis patients

(2020) C.A. Colque et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pseudomonas aeruginosa exoenzyme Y directly bundles actin filaments

(2020) Jordan M Mancl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Iron acquisition in Pseudomonas aeruginosa by the siderophore pyoverdine: an intricate interacting network including periplasmic and membrane proteins

(2020) Anne Bonneau et al.   Scientific Reports

Type VI secretion system of Pseudomonas aeruginosa is associated with biofilm formation but not environmental adaptation

(2020) Lihua Chen et al.   MicrobiologyOpen

Parallel evolutionary paths to produce more than one Pseudomonas aeruginosa biofilm phenotype

(2020) Janne G. Thöming et al.   npj Biofilms and Microbiomes

Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation

(2020) Sebastián A. Riquelme et al.   Cell Metabolism

A molecular mechanism for how sigma factor AlgT and transcriptional regulator AmrZ inhibit twitching motility in Pseudomonas aeruginosa

(2020) Anming Xu et al.   ENVIRONMENTAL MICROBIOLOGY

Sexual dimorphism in the microbiology of the CF ‘Gender Gap’: Estrogen modulation of Pseudomonas aeruginosa virulence

(2020) Jean Tyrrell et al.   STEROIDS

Heat Shock Protein DnaJ in Pseudomonas aeruginosa Affects Biofilm Formation via Pyocyanin Production

(2020) Bo Zeng et al.   Microorganisms

Overproduction of the AlgT sigma factor is lethal to mucoid Pseudomonas aeruginosa

(2020) Ashley R. Cross et al.   JOURNAL OF BACTERIOLOGY

Elevated exopolysaccharide levels in Pseudomonas aeruginosa flagellar mutants have implications for biofilm growth and chronic infections

(2020) Joe J. Harrison et al.   PLoS Genetics

Exoenzyme Y Contributes to End-Organ Dysfunction Caused by Pseudomonas aeruginosa Pneumonia in Critically Ill Patients: An Exploratory Study

(2020) Brant M. Wagener et al.   Toxins

The evolutionary trajectories of P. aeruginosa in biofilm and planktonic growth modes exposed to ciprofloxacin: beyond selection of antibiotic resistance

(2020) Marwa N. Ahmed et al.   npj Biofilms and Microbiomes

Factoring in the Complexity of the Cystic Fibrosis Lung to Understand Aspergillus fumigatus and Pseudomonas aeruginosa Interactions

(2020) Emily Beswick et al.   Pathogens

The extracellular polysaccharide matrix of Pseudomonas aeruginosa biofilms is a determinant of polymorphonuclear leukocyte responses

(2020) Morten Rybtke et al.   INFECTION AND IMMUNITY

Cell‐type specific hypertranslocation of effectors by the Pseudomonas aeruginosa type III secretion system

(2020) Erin I. Armentrout et al.   MOLECULAR MICROBIOLOGY

The evolution of virulence in Pseudomonas aeruginosa during chronic wound infection

(2020) Jelly Vanderwoude et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis

(2020) Elio Rossi et al.   NATURE REVIEWS MICROBIOLOGY

Bacterial persisters in long-term infection: Emergence and fitness in a complex host environment

(2020) Jennifer A. Bartell et al.   PLoS Pathogens

Pseudomonas Quinolone Signal-Induced Outer Membrane Vesicles Enhance Biofilm Dispersion in Pseudomonas aeruginosa

(2020) Adam C. Cooke et al.   mSphere

Understanding Pseudomonas aeruginosa–Host Interactions: The Ongoing Quest for an Efficacious Vaccine

(2020) Maite Sainz-Mejías et al.   Cells

Airway microenvironment alterations and pathogen growth in cystic fibrosis

(2019) Giovanni A. Rossi et al.   PEDIATRIC PULMONOLOGY

Persistence and Microevolution of Pseudomonas aeruginosa in the Cystic Fibrosis Lung: A Single-Patient Longitudinal Genomic Study

(2019) Irene Bianconi et al.   Frontiers in Microbiology

Genome-Based Approach Delivers Vaccine Candidates Against Pseudomonas aeruginosa

(2019) Irene Bianconi et al.   Frontiers in Immunology

Pseudomonas aeruginosa orchestrates twitching motility by sequential control of type IV pili movements

(2019) Lorenzo Talà et al.   Nature Microbiology

Neutrophilic proteolysis in the cystic fibrosis lung correlates with a pathogenic microbiome

(2019) Robert A. Quinn et al.   Microbiome

Challenges Facing Airway Epithelial Cell-Based Therapy for Cystic Fibrosis

(2019) Andrew Berical et al.   Frontiers in Pharmacology

Evolutionary highways to persistent bacterial infection

(2019) Jennifer A. Bartell et al.   Nature Communications

Remodeling of O Antigen in Mucoid Pseudomonas aeruginosa via Transcriptional Repression of wzz2

(2019) Ashley R. Cross et al.   mBio

Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients

(2019) Signe Agnete Møller et al.   Journal of Cystic Fibrosis

The essential role of hypermutation in rapid adaptation to antibiotic stress

(2019) Heer H. Mehta et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cystic Fibrosis and Pseudomonas aeruginosa: the Host-Microbe Interface

(2019) Sankalp Malhotra et al.   CLINICAL MICROBIOLOGY REVIEWS

Factors affecting the geographic variability of antibiotic-resistant healthcare-associated infections in the United States using the CDC Antibiotic Resistance Patient Safety Atlas

(2019) Julianne N. Kubes et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Pushing beyond the envelope: the potential roles of OprF in Pseudomonas aeruginosa biofilm formation and pathogenicity

(2019) Erin K. Cassin et al.   JOURNAL OF BACTERIOLOGY

Fitting pieces into the puzzle of Pseudomonas aeruginosa type III secretion system gene expression

(2019) Emily A. Williams McMackin et al.   JOURNAL OF BACTERIOLOGY

Mucoid Pseudomonas aeruginosa and regional inflammation in the cystic fibrosis lung

(2019) Sankalp Malhotra et al.   Journal of Cystic Fibrosis

Bacterial quorum‐sensing signal IQS induces host cell apoptosis by targeting POT1–p53 signalling pathway

(2019) Jianhe Wang et al.   CELLULAR MICROBIOLOGY

Antibiotic resistance in Pseudomonas aeruginosa – mechanisms, epidemiology and evolution

(2019) João Botelho et al.   DRUG RESISTANCE UPDATES

CFTR-PTEN–dependent mitochondrial metabolic dysfunction promotes Pseudomonas aeruginosa airway infection

(2019) Sebastián A. Riquelme et al.   Science Translational Medicine

Killing from the inside: Intracellular role of T3SS in the fate of Pseudomonas aeruginosa within macrophages revealed by mgtC and oprF mutants

(2019) Preeti Garai et al.   PLoS Pathogens

Relationship Between Quorum Sensing and Secretion Systems

(2019) Rocio Trastoy Pena et al.   Frontiers in Microbiology

Catabolism of Nucleic Acids by a Cystic Fibrosis Pseudomonas aeruginosa Isolate: An Adaptive Pathway to Cystic Fibrosis Sputum Environment

(2019) Sheemal Shanista Kumar et al.   Frontiers in Microbiology

Can Biofilm Be Reversed Through Quorum Sensing in Pseudomonas aeruginosa?

(2019) Shaomin Yan et al.   Frontiers in Microbiology

A systematic review and meta-analysis on Exo-toxins prevalence in hospital acquired Pseudomonas aeruginosa isolates

(2019) Fatemeh Javanmardi et al.   INFECTION GENETICS AND EVOLUTION

Quorum sensing-dependent post-secretional activation of extracellular proteases in Pseudomonas aeruginosa

(2019) Xi-Hui Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Membrane-Integrated Steric Chaperone Lif Facilitates Active Site Opening of Pseudomonas aeruginosa Lipase A

(2019) Neha Verma et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Structure and function of minor pilins of type IV pili

(2019) Theis Jacobsen et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Metabolomic studies of Pseudomonas aeruginosa

(2019) Karolina Anna Mielko et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Putting an end to the Pseudomonas aeruginosa IQS controversy

(2019) Pierre Cornelis   MicrobiologyOpen

Adapting to the Airways: Metabolic Requirements of Pseudomonas aeruginosa during the Infection of Cystic Fibrosis Patients

(2019) La Rosa et al.   Metabolites

Scavenging Bacterial Siderophores with Engineered Lipocalin Proteins as an Alternative Antimicrobial Strategy

(2019) Martin Dauner et al.   CHEMBIOCHEM

The third quorum-sensing system of Pseudomonas aeruginosa: Pseudomonas quinolone signal and the enigmatic PqsE protein

(2019) Selene García-Reyes et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Association of OprF mutant and disturbance of biofilm and pyocyanin virulence in pseudomonas aeruginosa

(2019) Sarah I. Bukhari et al.   SAUDI PHARMACEUTICAL JOURNAL

Pseudomonas aeruginosa uses multiple receptors for adherence to laminin during infection of the respiratory tract and skin wounds

(2019) Magnus Paulsson et al.   Scientific Reports

The Role of Pseudomonas aeruginosa Lipopolysaccharide in Bacterial Pathogenesis and Physiology

(2019) Steven M. Huszczynski et al.   Pathogens

Pseudomonas aeruginosa Biofilms: Host Response and Clinical Implications in Lung Infections

(2018) Nicholas M. Maurice et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pseudomonas aeruginosa and Klebsiella pneumoniae Adaptation to Innate Immune Clearance Mechanisms in the Lung

(2018) Sebastian A. Riquelme et al.   Journal of Innate Immunity

Interdependence between iron acquisition and biofilm formation in Pseudomonas aeruginosa

(2018) Donghoon Kang et al.   JOURNAL OF MICROBIOLOGY

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

(2018) Evelina Tacconelli et al.   LANCET INFECTIOUS DISEASES

Convergent Metabolic Specialization through Distinct Evolutionary Paths in Pseudomonas aeruginosa

(2018) Ruggero La Rosa et al.   mBio

Mixed Communities of Mucoid and Nonmucoid Pseudomonas aeruginosa Exhibit Enhanced Resistance to Host Antimicrobials

(2018) Sankalp Malhotra et al.   mBio

Pseudomonas aeruginosa type IV minor pilins and PilY1 regulate virulence by modulating FimS-AlgR activity

(2018) Victoria A. Marko et al.   PLoS Pathogens

Pseudomonas aeruginosa rugose small-colony variants evade host clearance, are hyper-inflammatory, and persist in multiple host environments

(2018) Matthew J. Pestrak et al.   PLoS Pathogens

The Pseudomonas Quinolone Signal (PQS): Not Just for Quorum Sensing Anymore

(2018) Jinshui Lin et al.   Frontiers in Cellular and Infection Microbiology

Cyclic-di-GMP and oprF Are Involved in the Response of Pseudomonas aeruginosa to Substrate Material Stiffness during Attachment on Polydimethylsiloxane (PDMS)

(2018) Fangchao Song et al.   Frontiers in Microbiology

Pseudomonas aeruginosa Protease IV Exacerbates Pneumococcal Pneumonia and Systemic Disease

(2018) Jessica L. Bradshaw et al.   mSphere

Mutation-Driven Evolution of Pseudomonas aeruginosa in the Presence of either Ceftazidime or Ceftazidime-Avibactam

(2018) Fernando Sanz-García et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Epidemiology, Biology, and Impact of Clonal Pseudomonas aeruginosa Infections in Cystic Fibrosis

(2018) Michael D. Parkins et al.   CLINICAL MICROBIOLOGY REVIEWS

Pseudomonas aeruginosa LasB Subverts Alveolar Macrophage Activity by Interfering With Bacterial Killing Through Downregulation of Innate Immune Defense, Reactive Oxygen Species Generation, and Complement Activation

(2018) Fabien Bastaert et al.   Frontiers in Immunology

Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies

(2018) Zheng Pang et al.   BIOTECHNOLOGY ADVANCES

Specific type IV pili groups in clinical isolates of Pseudomonas aeruginosa

(2018) Gertrudis Horna et al.   INTERNATIONAL MICROBIOLOGY

Unravelling the Interplay between Extracellular Acidosis and Immune Cells

(2018) Fernando Erra Díaz et al.   MEDIATORS OF INFLAMMATION

Adaptation of Pseudomonas aeruginosa to the chronic phenotype by mutations in the algTmucABD operon in isolates from Brazilian cystic fibrosis patients

(2018) Natália Candido Caçador et al.   PLoS One

Rapid diversification of Pseudomonas aeruginosa in cystic fibrosis lung-like conditions

(2018) Alana Schick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TesG is a type I secretion effector of Pseudomonas aeruginosa that suppresses the host immune response during chronic infection

(2018) Kelei Zhao et al.   Nature Microbiology

Pseudomonas aeruginosa quorum-sensing metabolite induces host immune cell death through cell surface lipid domain dissolution

(2018) Dingka Song et al.   Nature Microbiology

Bronchial microbiome, PA biofilm-forming capacity and exacerbation in severe COPD patients colonized by P. aeruginosa

(2017) Marian Garcia-Nuñez et al.   Future Microbiology

Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity

(2017) Sebastián A. Riquelme et al.   IMMUNITY

Pseudomonas aeruginosa quorum sensing modulates immune responses: An updated review article

(2017) Ashraf Kariminik et al.   IMMUNOLOGY LETTERS

Intensive care unit-acquired pneumonia due to Pseudomonas aeruginosa with and without multidrug resistance

(2017) Laia Fernández-Barat et al.   JOURNAL OF INFECTION

Pseudomonas aeruginosaLasB protease impairs innate immunity in mice and humans by targeting a lung epithelial cystic fibrosis transmembrane regulator–IL-6–antimicrobial–repair pathway

(2017) Vinciane Saint-Criq et al.   THORAX

Psl Produced by Mucoid Pseudomonas aeruginosa Contributes to the Establishment of Biofilms and Immune Evasion

(2017) Christopher J. Jones et al.   mBio

Membrane Distribution of the Pseudomonas Quinolone Signal Modulates Outer Membrane Vesicle Production in Pseudomonas aeruginosa

(2017) Catalina Florez et al.   mBio

Co-colonisation with Aspergillus fumigatus and Pseudomonas aeruginosa is associated with poorer health in cystic fibrosis patients: an Irish registry analysis

(2017) Emma Reece et al.   BMC Pulmonary Medicine

Advances in the causes and management of community acquired pneumonia in adults

(2017) Richard G Wunderink et al.   BMJ-British Medical Journal

Pseudomonas aeruginosa ExoU augments neutrophil transepithelial migration

(2017) Michael A. Pazos et al.   PLoS Pathogens

Advances in the causes and management of community acquired pneumonia in adults

(2017) Richard G Wunderink et al.   BMJ-British Medical Journal

Pseudomonas aeruginosa Lifestyle: A Paradigm for Adaptation, Survival, and Persistence

(2017) M. Fata Moradali et al.   Frontiers in Cellular and Infection Microbiology

Bacterial Secretant from Pseudomonas aeruginosa Dampens Inflammasome Activation in a Quorum Sensing-Dependent Manner

(2017) Jungmin Yang et al.   Frontiers in Immunology

Exoenzyme T Plays a Pivotal Role in the IFN-γ Production after Pseudomonas Challenge in IL-12 Primed Natural Killer Cells

(2017) Mickael Vourc’h et al.   Frontiers in Immunology

Molecular Epidemiology of Mutations in Antimicrobial Resistance Loci of Pseudomonas aeruginosa Isolates from Airways of Cystic Fibrosis Patients

(2016) Leonie Greipel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Molecular Interactions of Lipopolysaccharide with an Outer Membrane Protein from Pseudomonas aeruginosa Probed by Solution NMR

(2016) Iga Kucharska et al.   BIOCHEMISTRY

RsmW, Pseudomonas aeruginosa small non-coding RsmA-binding RNA upregulated in biofilm versus planktonic growth conditions

(2016) Christine L. Miller et al.   BMC MICROBIOLOGY

Role of CFTR in epithelial physiology

(2016) Vinciane Saint-Criq et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Microbiome in Cystic Fibrosis

(2016) Yvonne J. Huang et al.   CLINICS IN CHEST MEDICINE

Evolution of Ecological Diversity in Biofilms of Pseudomonas aeruginosa by Altered Cyclic Diguanylate Signaling

(2016) Kenneth M. Flynn et al.   JOURNAL OF BACTERIOLOGY

Clinical Isolates ofPseudomonas aeruginosafrom Chronically Infected Cystic Fibrosis Patients Fail To Activate the Inflammasome during Both Stable Infection and Pulmonary Exacerbation

(2016) Kelsey E. Huus et al.   JOURNAL OF IMMUNOLOGY

Surfactant Protein A Recognizes Outer Membrane Protein OprH onPseudomonas aeruginosaIsolates From Individuals With Chronic Infection

(2016) Mohammad Qadi et al.   JOURNAL OF INFECTIOUS DISEASES

A Pseudomonas aeruginosa hepta-acylated lipid A variant associated with cystic fibrosis selectively activates human neutrophils

(2016) Shuvasree SenGupta et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cystic fibrosis

(2016) J Stuart Elborn   LANCET

KEGG: new perspectives on genomes, pathways, diseases and drugs

(2016) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Chemotaxis and Binding of Pseudomonas aeruginosa to Scratch-Wounded Human Cystic Fibrosis Airway Epithelial Cells

(2016) Christian Schwarzer et al.   PLoS One

Pseudomonas aeruginosa Evolutionary Adaptation and Diversification in Cystic Fibrosis Chronic Lung Infections

(2016) Craig Winstanley et al.   TRENDS IN MICROBIOLOGY

Targeting the Type Three Secretion System in Pseudomonas aeruginosa

(2016) Ahalieyah Anantharajah et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Pseudomonas aeruginosa proteolytically alters the interleukin 22-dependent lung mucosal defense

(2016) Antoine Guillon et al.   Virulence

Cystic fibrosis lung environment and Pseudomonas aeruginosa infection

(2016) Anjali Y. Bhagirath et al.   BMC Pulmonary Medicine

Swimming Motility Mediates the Formation of Neutrophil Extracellular Traps Induced by Flagellated Pseudomonas aeruginosa

(2016) Madison Floyd et al.   PLoS Pathogens

Cellular Effects of Pyocyanin, a Secreted Virulence Factor of Pseudomonas aeruginosa

(2016) Susan Hall et al.   Toxins

The T6SSs of Pseudomonas aeruginosa Strain PAO1 and Their Effectors: Beyond Bacterial-Cell Targeting

(2016) Thibault G. Sana et al.   Frontiers in Cellular and Infection Microbiology

Neutrophils Discriminate between Lipopolysaccharides of Different Bacterial Sources and Selectively Release Neutrophil Extracellular Traps

(2016) Elmar Pieterse et al.   Frontiers in Immunology

Tracking the immunopathological response to Pseudomonas aeruginosa during respiratory infections

(2016) Cristina Cigana et al.   Scientific Reports

Evidence for Direct Control of Virulence and Defense Gene Circuits by the Pseudomonas aeruginosa Quorum Sensing Regulator, MvfR

(2016) Damien Maura et al.   Scientific Reports

Divergent, CoexistingPseudomonas aeruginosaLineages in Chronic Cystic Fibrosis Lung Infections

(2015) David Williams et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pseudomonas aeruginosa Pyocyanin Induces Neutrophil Death via Mitochondrial Reactive Oxygen Species and Mitochondrial Acid Sphingomyelinase

(2015) Antonella Managò et al.   ANTIOXIDANTS & REDOX SIGNALING

Comparative genomics and biological characterization of sequential Pseudomonas aeruginosa isolates from persistent airways infection

(2015) Irene Bianconi et al.   BMC GENOMICS

Genotypic and phenotypic analyses of a Pseudomonas aeruginosa chronic bronchiectasis isolate reveal differences from cystic fibrosis and laboratory strains

(2015) John J. Varga et al.   BMC GENOMICS

Regional Isolation Drives Bacterial Diversification within Cystic Fibrosis Lungs

(2015) Peter Jorth et al.   Cell Host & Microbe

Identification of OprF as a Complement Component C3 Binding Acceptor Molecule on the Surface of Pseudomonas aeruginosa

(2015) Meenu Mishra et al.   INFECTION AND IMMUNITY

The LasB Elastase of Pseudomonas aeruginosa Acts in Concert with Alkaline Protease AprA To Prevent Flagellin-Mediated Immune Recognition

(2015) Fiordiligie Casilag et al.   INFECTION AND IMMUNITY

Secretion of Flagellar Proteins by the Pseudomonas aeruginosa Type III Secretion-Injectisome System

(2015) Dilek Ince et al.   JOURNAL OF BACTERIOLOGY

Pseudomonas aeruginosa genotypes acquired by children with cystic fibrosis by age 5-years

(2015) Timothy J. Kidd et al.   Journal of Cystic Fibrosis

Phenotypic characterization of an international Pseudomonas aeruginosa reference panel: strains of cystic fibrosis (CF) origin show less in vivo virulence than non-CF strains

(2015) Louise Cullen et al.   MICROBIOLOGY-SGM

Persistent cystic fibrosis isolate Pseudomonas aeruginosa strain RP73 exhibits an under-acylated LPS structure responsible of its low inflammatory activity

(2015) Flaviana Di Lorenzo et al.   MOLECULAR IMMUNOLOGY

Enhanced annotations and features for comparing thousands ofPseudomonasgenomes in the Pseudomonas genome database

(2015) Geoffrey L. Winsor et al.   NUCLEIC ACIDS RESEARCH

PubChem Substance and Compound databases

(2015) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

Probing the Protein Interaction Network of Pseudomonas aeruginosa Cells by Chemical Cross-Linking Mass Spectrometry

(2015) Arti T. Navare et al.   STRUCTURE

Novel Type III Effectors in Pseudomonas aeruginosa

(2015) David Burstein et al.   mBio

Correction: The Role of ExoS in Dissemination of Pseudomonas aeruginosa during Pneumonia

(2015) Stephanie M. Rangel et al.   PLoS Pathogens

The absence of the Pseudomonas aeruginosa OprF protein leads to increased biofilm formation through variation in c-di-GMP level

(2015) Emeline Bouffartigues et al.   Frontiers in Microbiology

Pseudomonas Exotoxin A: optimized by evolution for effective killing

(2015) Marta Michalska et al.   Frontiers in Microbiology

Role of small colony variants in persistence of Pseudomonas aeruginosa infections in cystic fibrosis lungs

(2015) Jacob Malone   Infection and Drug Resistance

Cystic fibrosis-adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses

(2015) S. L. LaFayette et al.   Science Advances

Thapsigargin blocks Pseudomonas aeruginosa homoserine lactone-induced apoptosis in airway epithelia

(2014) Christian Schwarzer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Pseudomonas aeruginosa exoenzyme Y impairs endothelial cell proliferation and vascular repair following lung injury

(2014) Trevor C. Stevens et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Pseudomonas aeruginosaType-3 Secretion System Dampens Host Defense by Exploiting the NLRC4-coupled Inflammasome

(2014) Emmanuel Faure et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mutation-Driven β-Lactam Resistance Mechanisms among Contemporary Ceftazidime-Nonsusceptible Pseudomonas aeruginosa Isolates from U.S. Hospitals

(2014) Mariana Castanheira et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pseudomonas aeruginosabiofilm infections: From molecular biofilm biology to new treatment possibilities

(2014) Tim Tolker-Nielsen   APMIS

Coordination of Swarming Motility, Biosurfactant Synthesis, and Biofilm Matrix Exopolysaccharide Production in Pseudomonas aeruginosa

(2014) Shiwei Wang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Expression of the lipopolysaccharide biosynthesis gene lpxD affects biofilm formation of Pseudomonas aeruginosa

(2014) Sahar A. Alshalchi et al.   ARCHIVES OF MICROBIOLOGY

ExoY from Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for cGMP and cUMP formation

(2014) Urike Beckert et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Crystal structure of FliC flagellin from Pseudomonas aeruginosa and its implication in TLR5 binding and formation of the flagellar filament

(2014) Wan Seok Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Elastase LasB of Pseudomonas aeruginosa promotes biofilm formation partly through rhamnolipid-mediated regulation

(2014) Hua Yu et al.   CANADIAN JOURNAL OF MICROBIOLOGY

Influence of Virulence Genotype and Resistance Profile in the Mortality of Pseudomonas aeruginosa Bloodstream Infections

(2014) C. Pena et al.   CLINICAL INFECTIOUS DISEASES

Pseudomonaschemotaxis

(2014) Inmaculada Sampedro et al.   FEMS MICROBIOLOGY REVIEWS

Cystic fibrosis and bacterial colonization define the sputum N-glycosylation phenotype

(2014) Vignesh Venkatakrishnan et al.   GLYCOBIOLOGY

Lung disease modifier genes in cystic fibrosis

(2014) Loic Guillot et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Influence of O Polysaccharides on Biofilm Development and Outer Membrane Vesicle Biogenesis in Pseudomonas aeruginosa PAO1

(2014) K. Murphy et al.   JOURNAL OF BACTERIOLOGY

Pseudomonas aeruginosa injects NDK into host cells through a type III secretion system

(2014) Dennis Neeld et al.   MICROBIOLOGY-SGM

Protease IV, a quorum sensing-dependent protease ofPseudomonas aeruginosamodulates insect innate immunity

(2014) Su-Jin Park et al.   MOLECULAR MICROBIOLOGY

Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis

(2014) Rasmus Lykke Marvig et al.   NATURE GENETICS

Catalase (KatA) Plays a Role in Protection against Anaerobic Nitric Oxide in Pseudomonas aeruginosa

(2014) Shengchang Su et al.   PLoS One

Loss of Social Behaviours in Populations of Pseudomonas aeruginosa Infecting Lungs of Patients with Cystic Fibrosis

(2014) Natalie Jiricny et al.   PLoS One

The Mucoid Switch in Pseudomonas aeruginosa Represses Quorum Sensing Systems and Leads to Complex Changes to Stationary Phase Virulence Factor Regulation

(2014) Ben Ryall et al.   PLoS One

Surface attachment inducesPseudomonas aeruginosavirulence

(2014) Albert Siryaporn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pseudomonas aeruginosa elastase causes transient disruption of tight junctions and downregulation of PAR-2 in human nasal epithelial cells

(2014) Kazuaki Nomura et al.   RESPIRATORY RESEARCH

Environmental Heterogeneity Drives Within-Host Diversification and Evolution of Pseudomonas aeruginosa

(2014) T. Markussen et al.   mBio

Within-Host Evolution of Pseudomonas aeruginosa Reveals Adaptation toward Iron Acquisition from Hemoglobin

(2014) R. L. Marvig et al.   mBio

The ADP-Ribosyltransferase Domain of the Effector Protein ExoS Inhibits Phagocytosis of Pseudomonas aeruginosa during Pneumonia

(2014) S. M. Rangel et al.   mBio

Coexistence and Within-Host Evolution of Diversified Lineages of Hypermutable Pseudomonas aeruginosa in Long-term Cystic Fibrosis Infections

(2014) Sofía Feliziani et al.   PLoS Genetics

The hierarchy quorum sensing network in Pseudomonas aeruginosa

(2014) Jasmine Lee et al.   Protein & Cell

The deletion of TonB-dependent receptor genes is part of the genome reduction process that occurs during adaptation ofPseudomonas aeruginosato the cystic fibrosis lung

(2014) Jozef Dingemans et al.   Pathogens and Disease

The problems of antibiotic resistance in cystic fibrosis and solutions

(2014) Carla López-Causapé et al.   Expert Review of Respiratory Medicine

Interaction between extracellular lipase LipA and the polysaccharide alginate of Pseudomonas aeruginosa

(2013) Petra Tielen et al.   BMC MICROBIOLOGY

Flagellar Motility Is a Key Determinant of the Magnitude of the Inflammasome Response to Pseudomonas aeruginosa

(2013) Yash R. Patankar et al.   INFECTION AND IMMUNITY

Biofilm Matrix and Its Regulation in Pseudomonas aeruginosa

(2013) Qing Wei et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Diversity of  -lactam resistance mechanisms in cystic fibrosis isolates of Pseudomonas aeruginosa: a French multicentre study

(2013) C. Llanes et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Stringent Response Controls Catalases in Pseudomonas aeruginosa and Is Required for Hydrogen Peroxide and Antibiotic Tolerance

(2013) M. Khakimova et al.   JOURNAL OF BACTERIOLOGY

The AlgZR Two-Component System Recalibrates the RsmAYZ Posttranscriptional Regulatory System To Inhibit Expression of the Pseudomonas aeruginosa Type III Secretion System

(2013) P. J. Intile et al.   JOURNAL OF BACTERIOLOGY

Extensive diversification is a common feature of Pseudomonas aeruginosa populations during respiratory infections in cystic fibrosis

(2013) Abdul Ashish et al.   Journal of Cystic Fibrosis

Type IV Pilus ofPseudomonasaeruginosaConfers Resistance to Antimicrobial Activities of the Pulmonary Surfactant Protein-A

(2013) Rommel Max Tan et al.   Journal of Innate Immunity

IscR Modulates Catalase A (KatA) Activity, Peroxide Resistance, and Full Virulence of Pseudomonas aeruginosa PA14

(2013) Seol-Hee Kim   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

The involvement of rhamnolipids in microbial cell adhesion and biofilm development - an approach for control?

(2013) A. Nickzad et al.   LETTERS IN APPLIED MICROBIOLOGY

A cell-cell communication signal integrates quorum sensing and stress response

(2013) Jasmine Lee et al.   Nature Chemical Biology

The cystic fibrosis gender gap: Potential roles of estrogen

(2013) Neil B. Sweezey et al.   PEDIATRIC PULMONOLOGY

P. aeruginosa Lipopolysaccharide-Induced MUC5AC and CLCA3 Expression Is Partly through Duox1 In Vitro and In Vivo

(2013) Wen Li et al.   PLoS One

Phenotypic Heterogeneity of Pseudomonas aeruginosa Populations in a Cystic Fibrosis Patient

(2013) Matthew L. Workentine et al.   PLoS One

Surfactant Protein A Binds Flagellin Enhancing Phagocytosis and IL-1β Production

(2013) Anastasia K. Ketko et al.   PLoS One

Estrogen and the cystic fibrosis gender gap

(2013) Vinciane Saint-Criq et al.   STEROIDS

Type III Secretion of ExoU Is Critical during Early Pseudomonas aeruginosa Pneumonia

(2013) H. A. Howell et al.   mBio

Pseudomonas aeruginosa adapts its iron uptake strategies in function of the type of infections

(2013) Pierre Cornelis et al.   Frontiers in Cellular and Infection Microbiology

Pseudomonas aeruginosa: new insights into pathogenesis and host defenses

(2013) Shaan L. Gellatly et al.   Pathogens and Disease

Pseudomonas aeruginosaTwitching Motility: Type IV Pili in Action

(2012) Lori L. Burrows   Annual Review of Microbiology

Pseudomonas aeruginosa biofilm-associated homoserine lactone C12 rapidly activates apoptosis in airway epithelia

(2012) Christian Schwarzer et al.   CELLULAR MICROBIOLOGY

Pseudomonas aeruginosa-derived rhamnolipids subvert the host innate immune response through manipulation of the human beta-defensin-2 expression

(2012) Jomtje Dössel et al.   CELLULAR MICROBIOLOGY

Type 3 secretion system effector genotype and secretion phenotype of longitudinally collected Pseudomonas aeruginosa isolates from young children diagnosed with cystic fibrosis following newborn screening

(2012) H. Hu et al.   CLINICAL MICROBIOLOGY AND INFECTION

Targeting iron uptake to controlPseudomonas aeruginosainfections in cystic fibrosis

(2012) Daniel J. Smith et al.   EUROPEAN RESPIRATORY JOURNAL

Transmissible strains ofPseudomonas aeruginosain cystic fibrosis lung infections

(2012) Joanne L. Fothergill et al.   EUROPEAN RESPIRATORY JOURNAL

Flagella and bacterial pathogenicity

(2012) Qiangde Duan et al.   JOURNAL OF BASIC MICROBIOLOGY

Activation of the Epithelial Sodium Channel (ENaC) by the Alkaline Protease fromPseudomonas aeruginosa

(2012) Michael B. Butterworth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Second Type VI Secretion System ofPseudomonas aeruginosaStrain PAO1 Is Regulated by Quorum Sensing and Fur and Modulates Internalization in Epithelial Cells

(2012) Thibault G. Sana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Multiple Signaling Systems Regulating Virulence in Pseudomonas aeruginosa

(2012) P. Nadal Jimenez et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung

(2012) Alejandro A. Pezzulo et al.   NATURE

Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective

(2012) Anders Folkesson et al.   NATURE REVIEWS MICROBIOLOGY

Effect of Estrogen on Pseudomonas Mucoidy and Exacerbations in Cystic Fibrosis

(2012) Sanjay H. Chotirmall et al.   NEW ENGLAND JOURNAL OF MEDICINE

A dynamic and intricate regulatory network determines Pseudomonas aeruginosa virulence

(2012) Deepak Balasubramanian et al.   NUCLEIC ACIDS RESEARCH

HMDB 3.0—The Human Metabolome Database in 2013

(2012) David S. Wishart et al.   NUCLEIC ACIDS RESEARCH

ExoU Activates NF-κB and Increases IL-8/KC Secretion during Pseudomonas aeruginosa Infection

(2012) Carolina Diettrich Mallet de Lima et al.   PLoS One

The Pseudomonas aeruginosa Type III Secretion System Has an Exotoxin S/T/Y Independent Pathogenic Role during Acute Lung Infection

(2012) Marlies Galle et al.   PLoS One

Eight Stranded β -Barrel and Related Outer Membrane Proteins: Role in Bacterial Pathogenesis

(2012) Siobhan McClean   PROTEIN AND PEPTIDE LETTERS

Transcriptional Response of Mucoid Pseudomonas aeruginosa to Human Respiratory Mucus

(2012) V. Cattoir et al.   mBio

Pseudomonas aeruginosa Pili and Flagella Mediate Distinct Binding and Signaling Events at the Apical and Basolateral Surface of Airway Epithelium

(2012) Iwona Bucior et al.   PLoS Pathogens

Hemolytic Phospholipase C Inhibition Protects Lung Function duringPseudomonas aeruginosaInfection

(2011) Matthew J. Wargo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Contribution of an arsenal of virulence factors to pathogenesis of Pseudomonas aeruginosa infections

(2011) Tanya Strateva et al.   ANNALS OF MICROBIOLOGY

Role of Exopolysaccharides in Pseudomonas aeruginosa Biofilm Formation and Architecture

(2011) Aamir Ghafoor et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The role of alginate inPseudomonas aeruginosaEPS adherence, viscoelastic properties and cell attachment

(2011) Oded Orgad et al.   BIOFOULING

Microevolution of the major common Pseudomonas aeruginosa clones C and PA14 in cystic fibrosis lungs

(2011) Nina Cramer et al.   ENVIRONMENTAL MICROBIOLOGY

Cystic fibrosis modifier genes related to Pseudomonas aeruginosa infection

(2011) J E Park et al.   GENES AND IMMUNITY

Dampening Host Sensing and Avoiding Recognition inPseudomonas aeruginosaPneumonia

(2011) Cristina Cigana et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Pseudomonas aeruginosa Alkaline Protease Blocks Complement Activation via the Classical and Lectin Pathways

(2011) A. J. Laarman et al.   JOURNAL OF IMMUNOLOGY

Phospholipase C- 3 Is a Key Modulator of IL-8 Expression in Cystic Fibrosis Bronchial Epithelial Cells

(2011) V. Bezzerri et al.   JOURNAL OF IMMUNOLOGY

Characterization of protease IV expression in Pseudomonas aeruginosa clinical isolates

(2011) T. C. R. Conibear et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Pseudomonas aeruginosa PilY1 Binds Integrin in an RGD- and Calcium-Dependent Manner

(2011) Michael D. L. Johnson et al.   PLoS One

Pseudomonas aeruginosa Elastase Provides an Escape from Phagocytosis by Degrading the Pulmonary Surfactant Protein-A

(2011) Zhizhou Kuang et al.   PLoS One

Pseudomonas Evades Immune Recognition of Flagellin in Both Mammals and Plants

(2011) Bart W. Bardoel et al.   PLoS Pathogens

Genetic and Functional Diversity of Pseudomonas aeruginosa Lipopolysaccharide

(2011) Joseph S. Lam et al.   Frontiers in Microbiology

Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient

(2011) Jayasimha Rao et al.   Frontiers in Microbiology

Genetic Determinants Involved in the Susceptibility of Pseudomonas aeruginosa to  -Lactam Antibiotics

(2010) C. Alvarez-Ortega et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pseudomonas aeruginosa pilin activates the inflammasome

(2010) Cecilia S. Lindestam Arlehamn et al.   CELLULAR MICROBIOLOGY

Infection of human mucosal tissue by Pseudomonas aeruginosa requires sequential and mutually dependent virulence factors and a novel pilus-associated adhesin

(2010) Ryan W. Heiniger et al.   CELLULAR MICROBIOLOGY

Bacterial hypermutation in cystic fibrosis, not only for antibiotic resistance

(2010) A. Oliver et al.   CLINICAL MICROBIOLOGY AND INFECTION

Effects of rhamnolipids and shear on initial attachment of Pseudomonas aeruginosa PAO1 in glass flow chambers

(2010) Akhila Raya et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Lipase LipC affects motility, biofilm formation and rhamnolipid production in Pseudomonas aeruginosa

(2010) Frank Rosenau et al.   FEMS MICROBIOLOGY LETTERS

Full Virulence ofPseudomonas aeruginosaRequires OprF

(2010) Laurène Fito-Boncompte et al.   INFECTION AND IMMUNITY

Pseudomonas aeruginosa Evasion of Phagocytosis Is Mediated by Loss of Swimming Motility and Is Independent of Flagellum Expression

(2010) E. Amiel et al.   INFECTION AND IMMUNITY

Protein secretion systems in Pseudomonas aeruginosa: A wealth of pathogenic weapons

(2010) Sophie Bleves et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Adaptation of Pseudomonas aeruginosa during persistence in the cystic fibrosis lung

(2010) Michael Hogardt et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Increase in Rhamnolipid Synthesis under Iron-Limiting Conditions Influences Surface Motility and Biofilm Formation in Pseudomonas aeruginosa

(2010) R. Glick et al.   JOURNAL OF BACTERIOLOGY

Pseudomonas aeruginosa Increases Formation of Multidrug-Tolerant Persister Cells in Response to Quorum-Sensing Signaling Molecules

(2010) N. Moker et al.   JOURNAL OF BACTERIOLOGY

Extracellular enzymes affect biofilm formation of mucoid Pseudomonas aeruginosa

(2010) P. Tielen et al.   MICROBIOLOGY-SGM

Genome-wide analysis and literature-based survey of lipoproteins in Pseudomonas aeruginosa

(2010) K. Remans et al.   MICROBIOLOGY-SGM

The outer membrane protein OprQ and adherence of Pseudomonas aeruginosa to human fibronectin

(2010) A. Arhin et al.   MICROBIOLOGY-SGM

Pseudomonas Exotoxin A-Mediated Apoptosis Is Bak Dependent and Preceded by the Degradation of Mcl-1

(2010) X. Du et al.   MOLECULAR AND CELLULAR BIOLOGY

Quorum sensing-dependent virulence during Pseudomonas aeruginosa colonisation and pneumonia in mechanically ventilated patients

(2010) T. Kohler et al.   THORAX

Hypertonic Saline Therapy in Cystic Fibrosis: Do Population Shifts Caused by the Osmotic Sensitivity of Infecting Bacteria Explain the Effectiveness of this Treatment?

(2010) Huw D. Williams et al.   Frontiers in Microbiology

Azithromycin Maintains Airway Epithelial Integrity duringPseudomonas aeruginosaInfection

(2009) Skarphedinn Halldorsson et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Differential behaviour of Pseudomonas sp. 42A2 LipC, a lipase showing greater versatility than its counterpart LipA

(2009) Cristina Bofill et al.   BIOCHIMIE

Iron uptake regulation in Pseudomonas aeruginosa

(2009) Pierre Cornelis et al.   BIOMETALS

Genome-Wide Study of Pseudomonas aeruginosa Outer Membrane Protein Immunogenicity Using Self-Assembling Protein Microarrays

(2009) W. R. Montor et al.   INFECTION AND IMMUNITY

Review: Lipopolysaccharide biosynthesis in Pseudomonas aeruginosa

(2009) Jerry D. King et al.   Innate Immunity

The Major Catalase Gene (katA) of Pseudomonas aeruginosa PA14 Is under both Positive and Negative Control of the Global Transactivator OxyR in Response to Hydrogen Peroxide

(2009) Y.-J. Heo et al.   JOURNAL OF BACTERIOLOGY

Correlation Between the Lipopolysaccharide Expression and Adhesiveness of Clinical Isolates ofPseudomonas aeruginosa

(2009) Roudabeh J. Jamasbi et al.   Labmedicine

Truncation in the core oligosaccharide of lipopolysaccharide affects flagella-mediated motility in Pseudomonas aeruginosa PAO1 via modulation of cell surface attachment

(2009) T. Lindhout et al.   MICROBIOLOGY-SGM

Genetic adaptation of Pseudomonas aeruginosa during chronic lung infection of patients with cystic fibrosis: strong and weak mutators with heterogeneous genetic backgrounds emerge in mucA and/or lasR mutants

(2009) O. Ciofu et al.   MICROBIOLOGY-SGM

Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes

(2009) M. Alhede et al.   MICROBIOLOGY-SGM

Inactivation of the hmgA gene of Pseudomonas aeruginosa leads to pyomelanin hyperproduction, stress resistance and increased persistence in chronic lung infection

(2009) A. Rodriguez-Rojas et al.   MICROBIOLOGY-SGM

The type III secretion system of Pseudomonas aeruginosa: infection by injection

(2009) Alan R. Hauser   NATURE REVIEWS MICROBIOLOGY

Connecting Quorum Sensing, c-di-GMP, Pel Polysaccharide, and Biofilm Formation in Pseudomonas aeruginosa through Tyrosine Phosphatase TpbA (PA3885)

(2009) Akihiro Ueda et al.   PLoS Pathogens

Pseudomonas aeruginosa transmission is infrequent in New Zealand cystic fibrosis clinics

(2008) J. Schmid et al.   EUROPEAN RESPIRATORY JOURNAL

Pseudomonas exotoxin A: From virulence factor to anti-cancer agent

(2008) Philipp Wolf et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

The Peptidoglycan-Associated Lipoprotein OprL Helps Protect a Pseudomonas aeruginosa Mutant Devoid of the Transactivator OxyR from Hydrogen Peroxide-Mediated Killing during Planktonic and Biofilm Culture

(2008) W. Panmanee et al.   JOURNAL OF BACTERIOLOGY

Cystic fibrosis and estrogens: a perfect storm

(2008) Pamela L. Zeitlin   JOURNAL OF CLINICAL INVESTIGATION

Pseudomonas aeruginosa lasR mutants are associated with cystic fibrosis lung disease progression

(2008) Lucas R. Hoffman et al.   Journal of Cystic Fibrosis

Reactive oxygen species regulate Pseudomonas aeruginosa lipopolysaccharide-induced MUC5AC mucin expression via PKC-NADPH oxidase-ROS-TGF-α signaling pathways in human airway epithelial cells

(2007) Fugui Yan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS