Pseudomonas aeruginosa proteolytically alters the interleukin 22-dependent lung mucosal defense

Interleukin-22 receptor is overexpressed in nonsmall cell lung cancer and portends a poor prognosis

(2016) Antoine Guillon et al.   EUROPEAN RESPIRATORY JOURNAL

Is there a continuum between ventilator-associated tracheobronchitis and ventilator-associated pneumonia?

(2016) Saad Nseir et al.   INTENSIVE CARE MEDICINE

Neutrophil proteases alter the interleukin-22-receptor-dependent lung antimicrobial defence

(2015) Antoine Guillon et al.   EUROPEAN RESPIRATORY JOURNAL

Antibiotic treatment of ventilator-associated tracheobronchitis

(2014) Donald E. Craven et al.   Current Opinion in Critical Care

New Selective Peptidyl Di(chlorophenyl) Phosphonate Esters for Visualizing and Blocking Neutrophil Proteinase 3 in Human Diseases

(2014) Carla Guarino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pseudomonas aeruginosa eradicates Staphylococcus aureus by manipulating the host immunity

(2014) Erwan Pernet et al.   Nature Communications

VE-Cadherin Cleavage by LasB Protease from Pseudomonas aeruginosa Facilitates Type III Secretion System Toxicity in Endothelial Cells

(2014) Guillaume Golovkine et al.   PLoS Pathogens

IL-22, not simply a Th17 cytokine

(2013) Sascha Rutz et al.   IMMUNOLOGICAL REVIEWS

Candida albicans Airway Exposure Primes the Lung Innate Immune Response against Pseudomonas aeruginosa Infection through Innate Lymphoid Cell Recruitment and Interleukin-22-Associated Mucosal Response

(2013) Jean Baptiste Mear et al.   INFECTION AND IMMUNITY

Therapeutic opportunities of the IL-22–IL-22R1 system

(2013) Robert Sabat et al.   NATURE REVIEWS DRUG DISCOVERY

Disruption of the Endothelial Barrier by Proteases from the Bacterial Pathogen Pseudomonas aeruginosa: Implication of Matrilysis and Receptor Cleavage

(2013) Nathalie Beaufort et al.   PLoS One

Attributable Mortality of Ventilator-Associated Pneumonia

(2011) Maarten Bekaert et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Type II Secretion System of Pseudomonas aeruginosa: In Vivo Evidence of a Significant Role in Death Due to Lung Infection

(2011) Jeevan Jyot et al.   JOURNAL OF INFECTIOUS DISEASES

Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22

(2011) Gregory F Sonnenberg et al.   NATURE IMMUNOLOGY

Protein secretion systems in Pseudomonas aeruginosa: A wealth of pathogenic weapons

(2010) Sophie Bleves et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Proteases and antiproteases in chronic neutrophilic lung disease - relevance to drug discovery

(2009) Catherine M Greene et al.   BRITISH JOURNAL OF PHARMACOLOGY

Structural Characterization of Mouse Neutrophil Serine Proteases and Identification of Their Substrate Specificities

(2009) Timofey Kalupov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immunoproteomics To Examine Cystic Fibrosis Host Interactions with Extracellular Pseudomonas aeruginosa Proteins

(2008) H. G. Upritchard et al.   INFECTION AND IMMUNITY

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

(2008) Shean J Aujla et al.   NATURE MEDICINE

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE