Exoenzyme Y Contributes to End-Organ Dysfunction Caused by Pseudomonas aeruginosa Pneumonia in Critically Ill Patients: An Exploratory Study

Infection-induced endothelial amyloids impair memory

(2019) Ron Balczon et al.   FASEB JOURNAL

Ventilator Bundle and Its Effects on Mortality Among ICU Patients

(2018) Claudia Pileggi et al.   CRITICAL CARE MEDICINE

The Pseudomonas aeruginosa ExoY phenotype of high-copy-number recombinants is not detectable in natural isolates

(2018) Antje Munder et al.   Open Biology

The Role of Pseudomonas aeruginosa ExoY in an Acute Mouse Lung Infection Model

(2018) Christina Kloth et al.   Toxins

Nosocomial Pneumonia Elicits an Endothelial Proteinopathy: Evidence for a Source of Neurotoxic Amyloids in Critically Ill Patients

(2018) Mike T. Lin et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pseudomonas aeruginosa infection liberates transmissible, cytotoxic prion amyloids

(2017) Ron Balczon et al.   FASEB JOURNAL

Host and Pathogen Biomarkers for Severe Pseudomonas aeruginosa Infections

(2017) Carlos Juan et al.   JOURNAL OF INFECTIOUS DISEASES

Pseudomonas aeruginosa exoenzymes U and Y induce a transmissible endothelial proteinopathy

(2016) K. Adam Morrow et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Caspase-1 Activation Protects Lung Endothelial Barrier Function during Infection-Induced Stress

(2016) Diego F. Alvarez et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Ventilator-Associated Pneumonia Prevention Bundle Significantly Reduces the Risk of Ventilator-Associated Pneumonia in Critically Ill Burn Patients

(2016) Soman Sen et al.   Journal of Burn Care & Research

The implementation of a nonpharmacologic protocol to prevent intensive care delirium

(2016) Ryan M. Rivosecchi et al.   JOURNAL OF CRITICAL CARE

Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins

(2016) Alexander Belyy et al.   Nature Communications

Urinary tract infections caused by Pseudomonas aeruginosa among children in Southern Poland: Virulence factors and antibiotic resistance

(2016) M. Pobiega et al.   Journal of Pediatric Urology

Heterogeneity of pulmonary endothelial cyclic nucleotide response to Pseudomonas aeruginosa ExoY infection

(2015) K. A. Morrow et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Molecular characterization of carbapenem-resistant Pseudomonas aeruginosa strains isolated from patients with urinary tract infections in Southern Poland

(2015) Monika Pobiega et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

From canonical to non-canonical cyclic nucleotides as second messengers: Pharmacological implications

(2015) Roland Seifert et al.   PHARMACOLOGY & THERAPEUTICS

Influence of Virulence Genotype and Resistance Profile in the Mortality of Pseudomonas aeruginosa Bloodstream Infections

(2014) C. Pena et al.   CLINICAL INFECTIOUS DISEASES

One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome

(2014) Chen Yu Wang et al.   INTENSIVE CARE MEDICINE

Ubiquitin Activates Patatin-Like Phospholipases from Multiple Bacterial Species

(2014) David M. Anderson et al.   JOURNAL OF BACTERIOLOGY

Long-Term Mortality After Pneumonia in Cardiac Surgery Patients

(2014) J. Ibañez et al.   JOURNAL OF INTENSIVE CARE MEDICINE

Metformin-stimulated AMPK-α1 promotes microvascular repair in acute lung injury

(2013) Ming-Yuan Jian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Clinical relevance of the ESKAPE pathogens

(2013) Jack N Pendleton et al.   Expert Review of Anti-Infective Therapy

Preventing Delirium in the Intensive Care Unit

(2012) Nathan E. Brummel et al.   CRITICAL CARE CLINICS

Pseudomonas aeruginosaExotoxin Y Is a Promiscuous Cyclase That Increases Endothelial Tau Phosphorylation and Permeability

(2012) Cristhiaan D. Ochoa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hospital and long-term outcomes of ICU-treated severe community- and hospital-acquired, and ventilator-associated pneumonia patients

(2011) J. KARHU et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Reducing ventilator-associated pneumonia in intensive care: Impact of implementing a care bundle*

(2011) Andrew Conway Morris et al.   CRITICAL CARE MEDICINE

The Rickettsia prowazekii ExoU Homologue Possesses Phospholipase A1 (PLA1), PLA2, and Lyso-PLA2 Activities and Can Function in the Absence of Any Eukaryotic Cofactors In Vitro

(2011) N. A. Housley et al.   JOURNAL OF BACTERIOLOGY

Adenylate cyclase activity of Pseudomonas aeruginosa ExoY can mediate bleb-niche formation in epithelial cells and contributes to virulence

(2011) Victoria Hritonenko et al.   MICROBIAL PATHOGENESIS

The ADP-Ribosylation Domain of Pseudomonas aeruginosa ExoS Is Required for Membrane Bleb Niche Formation and Bacterial Survival within Epithelial Cells

(2010) A. A. Angus et al.   INFECTION AND IMMUNITY

A sensitive fluorescence-based assay for the detection of ExoU-mediated PLA2 activity

(2009) Marc A. Benson et al.   CLINICA CHIMICA ACTA

Role of Pseudomonas aeruginosa type III effectors in disease

(2009) Joanne Engel et al.   CURRENT OPINION IN MICROBIOLOGY

Persistent Infection withPseudomonas aeruginosain Ventilator-associated Pneumonia

(2008) Ali A. El Solh et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Comparison of type III secretion system virulence among fluoroquinolone-susceptible and -resistant clinical isolates of Pseudomonas aeruginosa

(2008) A. Wong-Beringer et al.   CLINICAL MICROBIOLOGY AND INFECTION