Clinical Isolates ofPseudomonas aeruginosafrom Chronically Infected Cystic Fibrosis Patients Fail To Activate the Inflammasome during Both Stable Infection and Pulmonary Exacerbation

Effects of genotype on rates of substitution during experimental evolution

(2015) Alex Wong et al.   EVOLUTION

Caspase-8 functions as a key mediator of inflammation and pro-IL-1β processing via both canonical and non-canonical pathways

(2015) Tom P. Monie et al.   IMMUNOLOGICAL REVIEWS

Secretion of Flagellar Proteins by the Pseudomonas aeruginosa Type III Secretion-Injectisome System

(2015) Dilek Ince et al.   JOURNAL OF BACTERIOLOGY

Acute effects of viral respiratory tract infections on sputum bacterial density during CF pulmonary exacerbations

(2015) Melanie Chin et al.   Journal of Cystic Fibrosis

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

(2015) Kate E. Lawlor et al.   Nature Communications

Pseudomonas aeruginosaType-3 Secretion System Dampens Host Defense by Exploiting the NLRC4-coupled Inflammasome

(2014) Emmanuel Faure et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Distinct Contributions of Interleukin-1α (IL-1α) and IL-1β to Innate Immune Recognition of Pseudomonas aeruginosa in the Lung

(2014) Khatoun Al Moussawi et al.   INFECTION AND IMMUNITY

IL-10 Function, Regulation, and in Bacterial Keratitis

(2014) Linda D. Hazlett et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF- B and MAPK signaling

(2014) N. H. Philip et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Lipid A Moieties Contribute to Pathogen-Induced Site-Specific Vascular Inflammation

(2014) Connie Slocum et al.   PLoS Pathogens

Flagellar Motility Is a Key Determinant of the Magnitude of the Inflammasome Response to Pseudomonas aeruginosa

(2013) Yash R. Patankar et al.   INFECTION AND IMMUNITY

Activation of inflammasome signaling mediates pathology of acute P. aeruginosa pneumonia

(2013) Taylor S. Cohen et al.   JOURNAL OF CLINICAL INVESTIGATION

Salmonella Infection Induces Recruitment of Caspase-8 to the Inflammasome To Modulate IL-1  Production

(2013) S. M. Man et al.   JOURNAL OF IMMUNOLOGY

Airway inflammation in cystic fibrosis: molecular mechanisms and clinical implications

(2013) Malena Cohen-Cymberknoh et al.   THORAX

Type 3 secretion system effector genotype and secretion phenotype of longitudinally collected Pseudomonas aeruginosa isolates from young children diagnosed with cystic fibrosis following newborn screening

(2012) H. Hu et al.   CLINICAL MICROBIOLOGY AND INFECTION

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation

(2012) James E. Vince et al.   IMMUNITY

Inflammasome Activators Induce Interleukin-1α Secretion via Distinct Pathways with Differential Requirement for the Protease Function of Caspase-1

(2012) Olaf Groß et al.   IMMUNITY

Cutting Edge: IL-1β Processing during Pseudomonas aeruginosa Infection Is Mediated by Neutrophil Serine Proteases and Is Independent of NLRC4 and Caspase-1

(2012) Mausita Karmakar et al.   JOURNAL OF IMMUNOLOGY

Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

(2012) Nirmal Robinson et al.   NATURE IMMUNOLOGY

Pseudomonas aeruginosaPopulation Diversity and Turnover in Cystic Fibrosis Chronic Infections

(2011) Eilidh Mowat et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

Many stimuli pull the necrotic trigger, an overview

(2011) N Vanlangenakker et al.   CELL DEATH AND DIFFERENTIATION

Airway Epithelial MyD88 Restores Control of Pseudomonas aeruginosa Murine Infection via an IL-1-Dependent Pathway

(2011) L. A. Mijares et al.   JOURNAL OF IMMUNOLOGY

Innate immune responses to Pseudomonas aeruginosa infection

(2011) Elise G. Lavoie et al.   MICROBES AND INFECTION

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

Inflammasome activation and IL-1  target IL-1  for secretion as opposed to surface expression

(2011) A. Fettelschoss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pseudomonas aeruginosa pilin activates the inflammasome

(2010) Cecilia S. Lindestam Arlehamn et al.   CELLULAR MICROBIOLOGY

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

In Vivo Discrimination of Type 3 Secretion System-Positive and -Negative Pseudomonas aeruginosa via a Caspase-1-Dependent Pathway

(2010) T. Wangdi et al.   INFECTION AND IMMUNITY

Newer antibacterial agents and their potential role in cystic fibrosis pulmonary exacerbation management

(2010) M. D. Parkins et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Molecular mechanisms of necroptosis: an ordered cellular explosion

(2010) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

(2010) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Trends in pathogens colonising the respiratory tract of adult patients with cystic fibrosis, 1985–2005

(2009) F.A. Millar et al.   Journal of Cystic Fibrosis

Fluctuations in phenotypes and genotypes within populations of Pseudomonas aeruginosa in the cystic fibrosis lung during pulmonary exacerbations

(2009) J. L. Fothergill et al.   JOURNAL OF MEDICAL MICROBIOLOGY

ThePseudomonas aeruginosa TypeIII secretion system plays a dual role in the regulation of caspase-1 mediated IL-1β maturation

(2008) M. Galle et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Pseudomonas aeruginosa activates caspase 1 through Ipaf

(2008) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA