Cellular Effects of Pyocyanin, a Secreted Virulence Factor of Pseudomonas aeruginosa

Discovery of an inhibitor of the production of thePseudomonas aeruginosavirulence factor pyocyanin in wild-type cells

(2016) Bernardas Morkunas et al.   Beilstein Journal of Organic Chemistry

Pseudomonas aeruginosa Pyocyanin Induces Neutrophil Death via Mitochondrial Reactive Oxygen Species and Mitochondrial Acid Sphingomyelinase

(2015) Antonella Managò et al.   ANTIOXIDANTS & REDOX SIGNALING

Pyocyanin inhibits both nitric oxide-dependent and -independent relaxation in porcine coronary arteries

(2015) Allison Hempenstall et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Development of Potent Inhibitors of Pyocyanin Production in Pseudomonas aeruginosa

(2015) Laura C. Miller et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pseudomonas pyocyanin stimulates IL-8 expression through MAPK and NF-κB pathways in differentiated U937 cells

(2014) Wenshu Chai et al.   BMC MICROBIOLOGY

Subversion of a Lysosomal Pathway Regulating Neutrophil Apoptosis by a Major Bacterial Toxin, Pyocyanin

(2014) L. R. Prince et al.   JOURNAL OF IMMUNOLOGY

Caenorhabditis elegans pathways that surveil and defend mitochondria

(2014) Ying Liu et al.   NATURE

Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection

(2014) Mark W. Pellegrino et al.   NATURE

Mitral valve endocarditis caused by Pseudomonas aeruginosa: a case report

(2014) Marija Polovina et al.   Journal of Infection in Developing Countries

Glutathione: new roles in redox signaling for an old antioxidant

(2014) Katia Aquilano et al.   Frontiers in Pharmacology

ERK1/2 activation modulates pyocyanin-induced toxicity in A549 respiratory epithelial cells

(2013) Amanda Forbes et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Evidence of Vascular Endothelial Dysfunction in Young Patients With Cystic Fibrosis

(2013) Spencer Poore et al.   CHEST

A Patient with Infective Endocarditis Caused by Community-acquired Pseudomonas aeruginosa Infection

(2013) Masahiko Setoguchi et al.   INTERNAL MEDICINE

Paradoxical Role of 3-Methyladenine in Pyocyanin-Induced Toxicity in 1321N1 Astrocytoma and SH-SY5Y Neuroblastoma Cells

(2013) Amelia J. McFarland et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Pyocyanin from Pseudomonas induces IL-8 production through the PKC and NF-κB pathways in U937 cells

(2013) WENSHU CHAI et al.   Molecular Medicine Reports

A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation

(2013) C. T. O'Loughlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alterations in acetylcholine, PGE2 and IL6 release from urothelial cells following treatment with pyocyanin and lipopolysaccharide

(2013) C. McDermott et al.   TOXICOLOGY IN VITRO

Phenazine Content in the Cystic Fibrosis Respiratory Tract Negatively Correlates with Lung Function and Microbial Complexity

(2012) Ryan C. Hunter et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses

(2012) Justine A. Melo et al.   CELL

Raloxifene attenuates Pseudomonas aeruginosa pyocyanin production and virulence

(2012) Shannan J. Ho Sui et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Effects of Pseudomonas Aeruginosa Virulence Factor Pyocyanin on Human Urothelial Cell Function and Viability

(2012) Catherine McDermott et al.   JOURNAL OF UROLOGY

Inhibition of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells by quorum sensing autoinducer-mimics

(2012) Bernardas Morkunas et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Pyocyanin Promotes Extracellular DNA Release in Pseudomonas aeruginosa

(2012) Theerthankar Das et al.   PLoS One

Pyocyanin effects on respiratory epithelium: relevance in Pseudomonas aeruginosa airway infections

(2012) Balázs Rada et al.   TRENDS IN MICROBIOLOGY

Inhibition of autophagy by 3-methyladenine protects 1321N1 astrocytoma cells against pyocyanin- and 1-hydroxyphenazine-induced toxicity

(2011) Amelia J. McFarland et al.   ARCHIVES OF TOXICOLOGY

Pseudomonas aeruginosa pyocyanin causes airway goblet cell hyperplasia and metaplasia and mucus hypersecretion by inactivating the transcriptional factor FoxA2

(2011) Yonghua Hao et al.   CELLULAR MICROBIOLOGY

Pyocyanin-induced toxicity in A549 respiratory cells is causally linked to oxidative stress

(2011) Lee S. Gloyne et al.   TOXICOLOGY IN VITRO

Reactive oxygen species mediate inflammatory cytokine release and EGFR-dependent mucin secretion in airway epithelial cells exposed to Pseudomonas pyocyanin

(2010) B Rada et al.   Mucosal Immunology

Pseudomonas pyocyanin inhibits wound repair by inducing premature cellular senescence: Role for p38 mitogen-activated protein kinase

(2009) Michael Muller et al.   BURNS

Urinary tract infections caused by Pseudomonas aeruginosa: A minireview

(2009) Rahul Mittal et al.   Journal of Infection and Public Health

Pseudomonas aeruginosa-Candida albicans Interactions: Localization and Fungal Toxicity of a Phenazine Derivative

(2008) J. Gibson et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Liver sinusoidal endothelial cells and acute non-oxidative hepatic injury induced by Pseudomonas aeruginosa pyocyanin

(2008) Rajkumar Cheluvappa et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Impairment of Apoptotic Cell Engulfment by Pyocyanin, a Toxic Metabolite ofPseudomonas aeruginosa

(2007) Stephen M. Bianchi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE