Activation of the Epithelial Sodium Channel (ENaC) by the Alkaline Protease fromPseudomonas aeruginosa

The Discovery of MMP7 Inhibitors Exploiting a Novel Selectivity Trigger

(2011) Karl Edman et al.   ChemMedChem

Atomic Force Microscopy Reveals the Architecture of the Epithelial Sodium Channel (ENaC)

(2011) Andrew P. Stewart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium-induced Folding and Stabilization of thePseudomonas aeruginosaAlkaline Protease

(2011) Liang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease

(2011) Zhe Zhou et al.   Journal of Cystic Fibrosis

Cleavage of endogenous γENaC and elevated abundance of αENaC are associated with increased Na+ transport in response to apical fluid volume expansion in human H441 airway epithelial cells

(2011) Chong D. Tan et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Human cystic fibrosis airway epithelia have reduced Cl- conductance but not increased Na+ conductance

(2011) O. A. Itani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pseudomonas Evades Immune Recognition of Flagellin in Both Mammals and Plants

(2011) Bart W. Bardoel et al.   PLoS Pathogens

Acute Regulation of the Epithelial Sodium Channel in Airway Epithelia by Proteases and Trafficking

(2010) Michael M. Myerburg et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Family Study of Restless Legs Syndrome in Quebec, Canada

(2010) Lan Xiong et al.   ARCHIVES OF NEUROLOGY

Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinases

(2010) Nicolas Guyot et al.   BIOLOGICAL CHEMISTRY

Allosteric Inhibition of the Epithelial Na+Channel through Peptide Binding at Peripheral Finger and Thumb Domains

(2010) Ossama B. Kashlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Cystic Fibrosis-causing Mutation ΔF508 Affects Multiple Steps in Cystic Fibrosis Transmembrane Conductance Regulator Biogenesis

(2010) Patrick H. Thibodeau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A mutation of the epithelial sodium channel associated with atypical cystic fibrosis increases channel open probability and reduces Na+self inhibition

(2010) Robert Rauh et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease

(2009) Abul Kalam Azad et al.   HUMAN MUTATION

ENaC at the Cutting Edge: Regulation of Epithelial Sodium Channels by Proteases

(2009) Thomas R. Kleyman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cftr and ENaC ion channels mediate NaCl absorption in the mouse submandibular gland

(2009) Marcelo A. Catalán et al.   JOURNAL OF PHYSIOLOGY-LONDON

SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage

(2009) A. Garcia-Caballero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prostasin expression is regulated by airway surface liquid volume and is increased in cystic fibrosis

(2008) Mike M. Myerburg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Proteolytic Processing of the Epithelial Sodium Channel γ Subunit Has a Dominant Role in Channel Activation

(2008) Marcelo D. Carattino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence of Reciprocal Reorientation of the Catalytic and Hemopexin-Like Domains of Full-Length MMP-12

(2008) Ivano Bertini et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY