The third quorum-sensing system of Pseudomonas aeruginosa: Pseudomonas quinolone signal and the enigmatic PqsE protein

PqsL uses reduced flavin to produce 2-hydroxylaminobenzoylacetate, a preferred PqsBC substrate in alkyl quinolone biosynthesis inPseudomonas aeruginosa

(2018) Steffen Lorenz Drees et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In Silico and in Vitro-Guided Identification of Inhibitors of Alkylquinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa

(2018) Fadi Soukarieh et al.   MOLECULES

The PqsE and RhlR proteins are an autoinducer synthase–receptor pair that control virulence and biofilm development in Pseudomonas aeruginosa

(2018) Sampriti Mukherjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of the Multidrug Resistance Efflux Pump MexCD-OprJ in the Pseudomonas aeruginosa Quorum Sensing Response

(2018) Manuel Alcalde-Rico et al.   Frontiers in Microbiology

Contribution of the Alkylquinolone Quorum-Sensing System to the Interaction of Pseudomonas aeruginosa With Bronchial Epithelial Cells

(2018) Yi-Chia Liu et al.   Frontiers in Microbiology

Distal and proximal promoters co-regulatepqsRexpression inPseudomonas aeruginosa

(2017) John M. Farrow et al.   MOLECULAR MICROBIOLOGY

PsrA controls the synthesis of the Pseudomonas aeruginosa quinolone signal via repression of the FadE homolog, PA0506

(2017) Greg Wells et al.   PLoS One

The RhlR quorum-sensing receptor controls Pseudomonas aeruginosa pathogenesis and biofilm development independently of its canonical homoserine lactone autoinducer

(2017) Sampriti Mukherjee et al.   PLoS Pathogens

Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds

(2016) Michael Zender et al.   ACS Chemical Biology

Pseudomonas aeruginosa ATCC 9027 is a non-virulent strain suitable for mono-rhamnolipids production

(2016) María-Victoria Grosso-Becerra et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Auto Poisoning of the Respiratory Chain by a Quorum-Sensing-Regulated Molecule Favors Biofilm Formation and Antibiotic Tolerance

(2016) Ronen Hazan et al.   CURRENT BIOLOGY

Crystal structure of Pseudomonas aeruginosa RsaL bound to promoter DNA reaffirms its role as a global regulator involved in quorum-sensing

(2016) Huaping Kang et al.   NUCLEIC ACIDS RESEARCH

Unravelling the Genome-Wide Contributions of Specific 2-Alkyl-4-Quinolones and PqsE to Quorum Sensing in Pseudomonas aeruginosa

(2016) Giordano Rampioni et al.   PLoS Pathogens

Cellular Effects of Pyocyanin, a Secreted Virulence Factor of Pseudomonas aeruginosa

(2016) Susan Hall et al.   Toxins

The role of 2,4-dihydroxyquinoline (DHQ) inPseudomonas aeruginosapathogenicity

(2016) Jordon D. Gruber et al.   PeerJ

Evidence for Direct Control of Virulence and Defense Gene Circuits by the Pseudomonas aeruginosa Quorum Sensing Regulator, MvfR

(2016) Damien Maura et al.   Scientific Reports

PqsE of Pseudomonas aeruginosa Acts as Pathway-Specific Thioesterase in the Biosynthesis of Alkylquinolone Signaling Molecules

(2015) Steffen Lorenz Drees et al.   CHEMISTRY & BIOLOGY

The Iron age of host-microbe interactions

(2015) M. P. Soares et al.   EMBO REPORTS

CysB Negatively Affects the Transcription ofpqsRand Pseudomonas Quinolone Signal Production in Pseudomonas aeruginosa

(2015) John M. Farrow et al.   JOURNAL OF BACTERIOLOGY

Pseudomonas aeruginosa clinical and environmental isolates constitute a single population with high phenotypic diversity

(2014) María-Victoria Grosso-Becerra et al.   BMC GENOMICS

The PqsR and RhlR Transcriptional Regulators Determine the Level of Pseudomonas Quinolone Signal Synthesis in Pseudomonas aeruginosa by Producing Two Different pqsABCDE mRNA Isoforms

(2014) S. Brouwer et al.   JOURNAL OF BACTERIOLOGY

The Pseudomonas Toxin Pyocyanin Inhibits the Dual Oxidase-Based Antimicrobial System as It Imposes Oxidative Stress on Airway Epithelial Cells

(2014) B. Rada et al.   JOURNAL OF IMMUNOLOGY

The End of an Old Hypothesis: The Pseudomonas Signaling Molecules 4-Hydroxy-2-Alkylquinolines Derive from Fatty Acids, Not 3-Ketofatty Acids

(2013) Carlos Eduardo Dulcey et al.   CHEMISTRY & BIOLOGY

Regulation of pqs quorum sensing via catabolite repression control in Pseudomonas aeruginosa

(2013) L. Zhang et al.   MICROBIOLOGY-SGM

A Quorum Sensing Small Volatile Molecule Promotes Antibiotic Tolerance in Bacteria

(2013) Yok-Ai Que et al.   PLoS One

Pseudomonas aeruginosa adapts its iron uptake strategies in function of the type of infections

(2013) Pierre Cornelis et al.   Frontiers in Cellular and Infection Microbiology

Transcriptional regulation by Ferric Uptake Regulator (Fur) in pathogenic bacteria

(2013) Bryan Troxell et al.   Frontiers in Cellular and Infection Microbiology

The Pseudomonas aeruginosa Transcriptome in Planktonic Cultures and Static Biofilms Using RNA Sequencing

(2012) Andreas Dötsch et al.   PLoS One

Redundant phenazine operons in Pseudomonas aeruginosa exhibit environment-dependent expression and differential roles in pathogenicity

(2012) D. A. Recinos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2-Heptyl-4-Quinolone, a Precursor of the Pseudomonas Quinolone Signal Molecule, Modulates Swarming Motility in Pseudomonas aeruginosa

(2011) D.-G. Ha et al.   JOURNAL OF BACTERIOLOGY

The small RNA PhrS stimulates synthesis of the Pseudomonas aeruginosa quinolone signal

(2011) Elisabeth Sonnleitner et al.   MOLECULAR MICROBIOLOGY

MexEF-OprN Efflux Pump Exports the Pseudomonas Quinolone Signal (PQS) Precursor HHQ (4-hydroxy-2-heptylquinoline)

(2011) Martin G. Lamarche et al.   PLoS One

Pseudomonas aeruginosa Elastase Provides an Escape from Phagocytosis by Degrading the Pulmonary Surfactant Protein-A

(2011) Zhizhou Kuang et al.   PLoS One

Correction: A Quorum Sensing Regulated Small Volatile Molecule Reduces Acute Virulence and Promotes Chronic Infection Phenotypes

(2011) Meenu Kesarwani et al.   PLoS Pathogens

mexEF-oprNMultidrug Efflux Operon ofPseudomonas aeruginosa: Regulation by the MexT Activator in Response to Nitrosative Stress and Chloramphenicol

(2010) Hossam Fetar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Transcriptomic analysis reveals a global alkyl-quinolone-independent regulatory role for PqsE in facilitating the environmental adaptation ofPseudomonas aeruginosato plant and animal hosts

(2010) Giordano Rampioni et al.   ENVIRONMENTAL MICROBIOLOGY

Anaerobic physiology of Pseudomonas aeruginosa in the cystic fibrosis lung

(2010) Max Schobert et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Secretion of Pseudomonas aeruginosa type III cytotoxins is dependent on pseudomonas quinolone signal concentration

(2010) G. Singh et al.   MICROBIAL PATHOGENESIS

Global gene expression analysis on the target genes of PQS and HHQ in J774A.1 monocyte/macrophage cells

(2010) Kiwan Kim et al.   MICROBIAL PATHOGENESIS

Oxygen levels rapidly modulate Pseudomonas aeruginosa social behaviours via substrate limitation of PqsH

(2010) Jeffrey W. Schertzer et al.   MOLECULAR MICROBIOLOGY

Structure Elucidation and Preliminary Assessment of Hydrolase Activity of PqsE, thePseudomonasQuinolone Signal (PQS) Response Protein

(2009) Shen Yu et al.   BIOCHEMISTRY

Pseudomonas aeruginosaquorum-sensing signal molecules interfere with dendritic cell-induced T-cell proliferation

(2009) Mette E. Skindersoe et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

HHQ and PQS, two Pseudomonas aeruginosa quorum-sensing molecules, down-regulate the innate immune responses through the nuclear factor-κB pathway

(2009) Kiwan Kim et al.   IMMUNOLOGY

Pseudomonas aeruginosain Chronic Obstructive Pulmonary Disease

(2008) Timothy F. Murphy et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The YebC Family Protein PA0964 Negatively Regulates the Pseudomonas aeruginosa Quinolone Signal System and Pyocyanin Production

(2008) H. Liang et al.   JOURNAL OF BACTERIOLOGY

PqsE Functions Independently of PqsR-Pseudomonas Quinolone Signal and Enhances the rhl Quorum-Sensing System

(2008) J. M. Farrow et al.   JOURNAL OF BACTERIOLOGY

Burkholderia pseudomallei, B. thailandensis, and B. ambifaria Produce 4-Hydroxy-2-Alkylquinoline Analogues with a Methyl Group at the 3 Position That Is Required for Quorum-Sensing Regulation

(2008) L. Vial et al.   JOURNAL OF BACTERIOLOGY

PqsD Is Responsible for the Synthesis of 2,4-Dihydroxyquinoline, an Extracellular Metabolite Produced byPseudomonas aeruginosa

(2008) Yong-Mei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY