The evolutionary trajectories of P. aeruginosa in biofilm and planktonic growth modes exposed to ciprofloxacin: beyond selection of antibiotic resistance

Mechanisms of ciprofloxacin resistance in Pseudomonas aeruginosa: new approaches to an old problem

(2019) Attika Rehman et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Integrated Experimental and Computational Analyses Reveal Differential Metabolic Functionality in Antibiotic-Resistant Pseudomonas aeruginosa

(2019) Laura J. Dunphy et al.   Cell Systems

Social Behavior of Antibiotic Resistant Mutants Within Pseudomonas aeruginosa Biofilm Communities

(2019) Estrella Rojo-Molinero et al.   Frontiers in Microbiology

Gamblers: An Antibiotic-Induced Evolvable Cell Subpopulation Differentiated by Reactive-Oxygen-Induced General Stress Response

(2019) John P. Pribis et al.   MOLECULAR CELL

Lack of the major multifunctional catalase KatA in P.aeruginosa accelerates evolution of antibiotic resistance in ciprofloxacin-treated biofilms

(2019) Marwa N. Ahmed et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibiotic Resistance Evolution Is Contingent on the Quorum-Sensing Response in Pseudomonas aeruginosa

(2019) Sara Hernando-Amado et al.   MOLECULAR BIOLOGY AND EVOLUTION

Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms

(2019) Aurélie Crabbé et al.   TRENDS IN MICROBIOLOGY

A large-scale whole-genome comparison shows that experimental evolution in response to antibiotics predicts changes in naturally evolved clinical Pseudomonas aeruginosa

(2019) Samuel J. T. Wardell et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evolution of antibiotic resistance in biofilm and planktonic P. aeruginosa populations exposed to sub-inhibitory levels of ciprofloxacin

(2018) Marwa N. Ahmed et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Drug-Driven Phenotypic Convergence Supports Rational Treatment Strategies of Chronic Infections

(2018) Lejla Imamovic et al.   CELL

The Versatile Mutational Resistome of Pseudomonas aeruginosa

(2018) Carla López-Causapé et al.   Frontiers in Microbiology

Antibiotic-Induced Genetic Variation: How It Arises and How It Can Be Prevented

(2018) Jesús Blázquez et al.   Annual Review of Microbiology

Mutations causing low level antibiotic resistance ensure bacterial survival in antibiotic-treated hosts

(2018) Jakob Frimodt-Møller et al.   Scientific Reports

Metabolic Compensation of Fitness Costs Is a General Outcome for Antibiotic-Resistant Pseudomonas aeruginosa Mutants Overexpressing Efflux Pumps

(2017) Jorge Olivares Pacheco et al.   mBio

Evolved Aztreonam Resistance Is Multifactorial and Can Produce Hypervirulence in Pseudomonas aeruginosa

(2017) Peter Jorth et al.   mBio

The phenotypic evolution of Pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin

(2016) Tina Wassermann et al.   MICROBIOLOGY-SGM

Pseudomonas aeruginosa Evolutionary Adaptation and Diversification in Cystic Fibrosis Chronic Lung Infections

(2016) Craig Winstanley et al.   TRENDS IN MICROBIOLOGY

Within-host microevolution of Pseudomonas aeruginosa in Italian cystic fibrosis patients

(2015) Rasmus Lykke Marvig et al.   BMC MICROBIOLOGY

ESCMID∗ guideline for the diagnosis and treatment of biofilm infections 2014

(2015) N. Høiby et al.   CLINICAL MICROBIOLOGY AND INFECTION

Evolutionary insight from whole-genome sequencing of Pseudomonas aeruginosa from cystic fibrosis patients

(2015) Rasmus Lykke Marvig et al.   Future Microbiology

Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection

(2015) Karin Meinike Jørgensen et al.   MICROBIOLOGY-SGM

Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations

(2014) Ofer Fridman et al.   NATURE

Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis

(2014) Rasmus Lykke Marvig et al.   NATURE GENETICS

Microbiological effects of sublethal levels of antibiotics

(2014) Dan I. Andersson et al.   NATURE REVIEWS MICROBIOLOGY

Sublethal Ciprofloxacin Treatment Leads to Rapid Development of High-Level Ciprofloxacin Resistance during Long-Term Experimental Evolution of Pseudomonas aeruginosa

(2013) Karin Meinike Jørgensen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Selection of resistance at lethal and non-lethal antibiotic concentrations

(2012) Diarmaid Hughes et al.   CURRENT OPINION IN MICROBIOLOGY

Antimicrobials as promoters of genetic variation

(2012) Jesús Blázquez et al.   CURRENT OPINION IN MICROBIOLOGY

Dynamics of Mutator and Antibiotic-Resistant Populations in a Pharmacokinetic/Pharmacodynamic Model of Pseudomonas aeruginosa Biofilm Treatment

(2011) María D. Macià et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evolutionary dynamics of bacteria in a human host environment

(2011) L. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selection of Resistant Bacteria at Very Low Antibiotic Concentrations

(2011) Erik Gullberg et al.   PLoS Pathogens

Sublethal Antibiotic Treatment Leads to Multidrug Resistance via Radical-Induced Mutagenesis

(2010) Michael A. Kohanski et al.   MOLECULAR CELL

Parallel Evolution in Pseudomonas aeruginosa over 39,000 Generations In Vivo

(2010) H. K. Huse et al.   mBio

Nitric Oxide Signaling in Pseudomonas aeruginosa Biofilms Mediates Phosphodiesterase Activity, Decreased Cyclic Di-GMP Levels, and Enhanced Dispersal

(2009) N. Barraud et al.   JOURNAL OF BACTERIOLOGY

Swarming of Pseudomonas aeruginosa Is a Complex Adaptation Leading to Increased Production of Virulence Factors and Antibiotic Resistance

(2008) J. Overhage et al.   JOURNAL OF BACTERIOLOGY