Evidence for Direct Control of Virulence and Defense Gene Circuits by the Pseudomonas aeruginosa Quorum Sensing Regulator, MvfR

Auto Poisoning of the Respiratory Chain by a Quorum-Sensing-Regulated Molecule Favors Biofilm Formation and Antibiotic Tolerance

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Unraveling the Physiological Complexities of Antibiotic Lethality

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Identification of Anti-virulence Compounds That Disrupt Quorum-Sensing Regulated Acute and Persistent Pathogenicity

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Are Reactive Oxygen Species Always Detrimental to Pathogens?

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The Stringent Response Controls Catalases in Pseudomonas aeruginosa and Is Required for Hydrogen Peroxide and Antibiotic Tolerance

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A Quorum Sensing Small Volatile Molecule Promotes Antibiotic Tolerance in Bacteria

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Structural Basis for Native Agonist and Synthetic Inhibitor Recognition by the Pseudomonas aeruginosa Quorum Sensing Regulator PqsR (MvfR)

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Pseudomonas aeruginosa: new insights into pathogenesis and host defenses

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Identification of Small-Molecule Antagonists of the Pseudomonas aeruginosa Transcriptional Regulator PqsR: Biophysically Guided Hit Discovery and Optimization

(2012) Tobias Klein et al.   ACS Chemical Biology

Purification, crystallization and preliminary X-ray diffraction analysis of the C-terminal fragment of the MvfR protein fromPseudomonas aeruginosa

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Discovery of Antagonists of PqsR, a Key Player in 2-Alkyl-4-quinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa

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Validation of PqsD as an Anti-biofilm Target in Pseudomonas aeruginosa by Development of Small-Molecule Inhibitors

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The Quorum Sensing Volatile Molecule 2-Amino Acetophenon Modulates Host Immune Responses in a Manner that Promotes Life with Unwanted Guests

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Current Epidemiology and Growing Resistance of Gram-Negative Pathogens

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The ferritin-like protein Dps protects Salmonella enterica serotype Enteritidis from the Fenton-mediated killing mechanism of bactericidal antibiotics

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The Role of Reactive-Oxygen-Species in Microbial Persistence and Inflammation

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Cooperation and cheating in Pseudomonas aeruginosa: the roles of the las, rhl and pqs quorum-sensing systems

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A Quorum Sensing Regulated Small Volatile Molecule Reduces Acute Virulence and Promotes Chronic Infection Phenotypes

(2011) Meenu Kesarwani et al.   PLoS Pathogens

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(2010) Kim Lewis   Annual Review of Microbiology

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Structure, function and regulation of the DNA-binding protein Dps and its role in acid and oxidative stress resistance in Escherichia coli: a review

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Iron Homeostasis Affects Antibiotic-mediated Cell Death inPseudomonasSpecies

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Homeostatic Interplay between Bacterial Cell-Cell Signaling and Iron in Virulence

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Antibacterial-Resistant Pseudomonas aeruginosa: Clinical Impact and Complex Regulation of Chromosomally Encoded Resistance Mechanisms

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Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules

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Pseudomonas aeruginosa: a formidable and ever-present adversary

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Revisiting the quorum-sensing hierarchy in Pseudomonas aeruginosa: the transcriptional regulator RhlR regulates LasR-specific factors

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Global position analysis of thePseudomonas aeruginosaquorum-sensing transcription factor LasR

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PqsE Functions Independently of PqsR-Pseudomonas Quinolone Signal and Enhances the rhl Quorum-Sensing System

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The Escherichia coli RutR transcription factor binds at targets within genes as well as intergenic regions

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H-NS family members function coordinately in an opportunistic pathogen

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The Pseudomonas Quinolone Signal (PQS) Balances Life and Death in Pseudomonas aeruginosa Populations

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