Alzheimer’s Disease: An Updated Overview of Its Genetics

Sex differences in cognitive resilience in preclinical autosomal‐dominant Alzheimer's disease carriers and non‐carriers: Baseline findings from the API ADAD Colombia Trial

(2022) Clara Vila‐Castelar et al.   Alzheimers & Dementia

The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model

(2022) Christel Claes et al.   Alzheimers & Dementia

Progress on the roles of MEF2C in neuropsychiatric diseases

(2022) Zhikun Zhang et al.   Molecular Brain

The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

(2022) Erwan Lambert et al.   Acta Neuropathologica Communications

Alzheimer’s Disease and Tau Self-Assembly: In the Search of the Missing Link

(2022) Andrea González et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Association of SPI1 Haplotypes with Altered SPI1 Gene Expression and Alzheimer’s Disease Risk

(2022) Han Cao et al.   JOURNAL OF ALZHEIMERS DISEASE

Dysregulation of ACE-1 in Normal Aging and the Early Stages of Alzheimer’s Disease

(2022) Robert MacLachlan et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Whole-genome sequencing reveals novel ethnicity-specific rare variants associated with Alzheimer’s disease

(2022) Daichi Shigemizu et al.   MOLECULAR PSYCHIATRY

New insights into the genetic etiology of Alzheimer’s disease and related dementias

(2022) Céline Bellenguez et al.   NATURE GENETICS

Advances in the Structural and Physiological Functions of SHARPIN

(2022) Beiming Yu et al.   Frontiers in Immunology

Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia

(2022) Diego Sepulveda-Falla et al.   ACTA NEUROPATHOLOGICA

PILRA polymorphism modifies the effect of APOE4 and GM17 on Alzheimer’s disease risk

(2022) Karin Lopatko Lindman et al.   Scientific Reports

Epigenetics in Alzheimer’s Disease

(2022) Xiaodie Gao et al.   Frontiers in Aging Neuroscience

The 677C > T variant in methylenetetrahydrofolate reductase causes morphological and functional cerebrovascular deficits in mice

(2022) Alaina M Reagan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

PLCγ2 impacts microglia-related effectors revealing variants and pathways important in Alzheimer’s disease

(2022) Ke Li et al.   Frontiers in Cell and Developmental Biology

The common genes involved in the pathogenesis of Alzheimer's disease and type 2 diabetes and their implication for drug repositioning

(2022) Xin Yuan et al.   NEUROPHARMACOLOGY

Lecanemab in Early Alzheimer’s Disease

(2022) Christopher H. van Dyck et al.   NEW ENGLAND JOURNAL OF MEDICINE

SHARPIN: Role in Finding NEMO and in Amyloid-Beta Clearance and Degradation (ABCD) Pathway in Alzheimer’s Disease?

(2021) Dhanya Krishnan et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Deletion of Alzheimer's disease‐associated CD33 results in an inflammatory human microglia phenotype

(2021) Jannis Wißfeld et al.   GLIA

The Neurovascular Unit Dysfunction in Alzheimer’s Disease

(2021) Luis O. Soto-Rojas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer’s disease pathogenesis

(2021) Aliza P. Wingo et al.   NATURE GENETICS

Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer’s disease risk genes

(2021) Jeremy Schwartzentruber et al.   NATURE GENETICS

Genome-wide epistasis analysis for Alzheimer’s disease and implications for genetic risk prediction

(2021) Hui Wang et al.   Alzheimers Research & Therapy

An APP ectodomain mutation outside of the Aβ domain promotes Aβ production in vitro and deposition in vivo

(2021) Xulun Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TREM2, microglia, and Alzheimer’s disease

(2021) Qi Qin et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Type I interferon response-related microglial Mef2c deregulation at the onset of Alzheimer's pathology in 5×FAD mice

(2021) Feng Xue et al.   NEUROBIOLOGY OF DISEASE

PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer’s disease

(2021) Alex G. Nackenoff et al.   PLoS Genetics

Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer’s disease pathologies

(2021) Guiqin Chen et al.   Science Advances

Priming of NLRP3 inflammasome activation by Msn kinase MINK1 in macrophages

(2021) Kaixiang Zhu et al.   Cellular & Molecular Immunology

Alzheimer's disease BIN1 coding variants increase intracellular Aβ levels by interfering with BACE1 recycling

(2021) Catarina Perdigão et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia

(2021) Andy P. Tsai et al.   NEUROBIOLOGY OF DISEASE

Explore the role of CR1 genetic variants in late-onset Alzheimer’s disease susceptibility

(2021) Liu Lu et al.   PSYCHIATRIC GENETICS

Early Life Nutrition and Mental Health: The Role of DNA Methylation

(2021) Rola A Bekdash   Nutrients

Modest changes in Spi1 dosage reveal the potential for altered microglial function as seen in Alzheimer’s disease

(2021) Ruth E. Jones et al.   Scientific Reports

TOMM40 RNA Transcription in Alzheimer’s Disease Brain and Its Implication in Mitochondrial Dysfunction

(2021) Eun-Gyung Lee et al.   Genes

MEF2C ameliorates learning, memory, and molecular pathological changes in Alzheimer’s disease <italic>in vivo</italic> and<?A3B2 ACK?><italic>in vitro</italic>

(2021) Jiamou Ren et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Genomics of Alzheimer’s disease implicates the innate and adaptive immune systems

(2021) Yihan Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer’s disease

(2021) Young Ho Park et al.   Alzheimers Research & Therapy

A missense variant in SHARPIN mediates Alzheimer’s disease-specific brain damages

(2021) Jun Young Park et al.   Translational Psychiatry

The Influence of MTHFR Polymorphism on Gray Matter Volume in Patients With Amnestic Mild Cognitive Impairment

(2021) Mengzhe You et al.   Frontiers in Neuroscience

Deletion of Abi3 gene locus exacerbates neuropathological features of Alzheimer’s disease in a mouse model of Aβ amyloidosis

(2021) Hande Karahan et al.   Science Advances

Interaction between APOE4 and herpes simplex virus type 1 in Alzheimer's disease

(2020) Morgane Linard et al.   Alzheimers & Dementia

A novel role for SHARPIN in amyloid-β phagocytosis and inflammation by peripheral blood- derived macrophages in Alzheimer’s disease

(2020) Dhanya Krishnan et al.   NEUROBIOLOGY OF AGING

PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment

(2020) Luca Kleineidam et al.   ACTA NEUROPATHOLOGICA

Genetic Association Between Alzheimer’s Disease Risk Variant of the PICALM Gene and EEG Functional Connectivity in Non-demented Adults

(2020) Natalya Ponomareva et al.   Frontiers in Neuroscience

The Mechanistic Role of Bridging Integrator 1 (BIN1) in Alzheimer’s Disease

(2020) Peirong Gao et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Gene therapy for Alzheimer’s disease targeting CD33 reduces amyloid beta accumulation and neuroinflammation

(2020) Ana Griciuc et al.   HUMAN MOLECULAR GENETICS

Alternative Splicing Regulation of an Alzheimer’s Risk Variant in CLU

(2020) Seonggyun Han et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exploring the Role of CLU in the Pathogenesis of Alzheimer’s Disease

(2020) Md. Sahab Uddin et al.   NEUROTOXICITY RESEARCH

PICALM Rescues Endocytic Defects Caused by the Alzheimer’s Disease Risk Factor APOE4

(2020) Priyanka Narayan et al.   Cell Reports

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel

(2020) Brian W. Kunkle et al.   JAMA Neurology

Comprehensive Review on Alzheimer’s Disease: Causes and Treatment

(2020) Zeinab Breijyeh et al.   MOLECULES

AMPK: A bridge between diabetes mellitus and Alzheimer's disease

(2020) Meixiang Chen et al.   BEHAVIOURAL BRAIN RESEARCH

Genetic variants in glutamate-, Aβ−, and tau-related pathways determine polygenic risk for Alzheimer's disease

(2020) Ted Lawingco et al.   NEUROBIOLOGY OF AGING

Amyloid-β Immunotherapy for Alzheimer's Disease - Is It Now A Long Shot…?

(2019) Francesco Panza et al.   ANNALS OF NEUROLOGY

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

(2019) Iris E. Jansen et al.   NATURE GENETICS

Genome-wide analysis of genetic predisposition to Alzheimer’s disease and related sex disparities

(2019) Alireza Nazarian et al.   Alzheimers Research & Therapy

Prediction of Alzheimer’s Disease-Associated Genes by Integration of GWAS Summary Data and Expression Data

(2019) Sicheng Hao et al.   Frontiers in Genetics

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

(2019) Brian W. Kunkle et al.   NATURE GENETICS

Alterations in cholesterol metabolism as a risk factor for developing Alzheimer's disease: Potential novel targets for treatment

(2019) Raúl Loera-Valencia et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

ApoE4: an emerging therapeutic target for Alzheimer’s disease

(2019) Mirna Safieh et al.   BMC Medicine

SORL1 genetic variants and Alzheimer disease risk: a literature review and meta-analysis of sequencing data

(2019) Dominique Campion et al.   ACTA NEUROPATHOLOGICA

The role of ABCA7 in Alzheimer’s disease: evidence from genomics, transcriptomics and methylomics

(2019) Arne De Roeck et al.   ACTA NEUROPATHOLOGICA

ADAM10 in Alzheimer's disease: Pharmacological modulation by natural compounds and its role as a peripheral marker

(2019) Patricia Regina Manzine et al.   BIOMEDICINE & PHARMACOTHERAPY

Benefits and limitations of genome-wide association studies

(2019) Vivian Tam et al.   NATURE REVIEWS GENETICS

Neural regeneration therapies for Alzheimer's and Parkinson's disease-related disorders

(2019) Arubala P. Reddy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The PILRA G78R Variant Correlates with Higher HSV-1-Specific IgG Titers in Alzheimer’s Disease

(2019) Simone Agostini et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

A rare functional variant of SHARPIN attenuates the inflammatory response and associates with increased risk of late-onset Alzheimer’s disease

(2019) Yuya Asanomi et al.   MOLECULAR MEDICINE

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies

(2019) Yu Yamazaki et al.   Nature Reviews Neurology

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

(2019) Justin M. Long et al.   CELL

Genome-Wide Methylation of Mild Cognitive Impairment in Mexican Americans Highlights Genes Involved in Synaptic Transport, Alzheimer’s Disease-Precursor Phenotypes, and Metabolic Morbidities

(2019) Gita A. Pathak et al.   JOURNAL OF ALZHEIMERS DISEASE

ABCA7 and EphA1 Genes Polymorphisms in Late-Onset Alzheimer’s Disease

(2019) Mahnaz Talebi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

3-O -Sulfation of Heparan Sulfate Enhances Tau Interaction and Cellular Uptake

(2019) Jing Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aging and Alzheimer's disease pathology

(2019) Renpei Sengoku   NEUROPATHOLOGY

The Post-GWAS Era: From Association to Function

(2018) Michael D. Gallagher et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Pathway to Tau Modifications and the Origins of Alzheimer's Disease

(2018) Ricardo B. Maccioni et al.   ARCHIVES OF MEDICAL RESEARCH

Neuroimmune Tau Mechanisms: Their Role in the Progression of Neuronal Degeneration

(2018) Nicole Cortés et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exploring the mechanistic insights of Cas scaffolding protein family member 4 with protein tyrosine kinase 2 in Alzheimer’s disease by evaluating protein interactions through molecular docking and dynamic simulations

(2018) Mubashir Hassan et al.   NEUROLOGICAL SCIENCES

Amyloid toxicity in Alzheimer’s disease

(2018) Allison B. Reiss et al.   REVIEWS IN THE NEUROSCIENCES

GWAS on family history of Alzheimer’s disease

(2018) Riccardo E. Marioni et al.   Translational Psychiatry

Alzheimer’s disease hypothesis and related therapies

(2018) Xiaoguang Du et al.   Translational Neurodegeneration

Hazardous effects of chemical pesticides on human health–Cancer and other associated disorders

(2018) Akash Sabarwal et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Centenarian controls increase variant effect sizes by an average twofold in an extreme case–extreme control analysis of Alzheimer’s disease

(2018) Niccolò Tesi et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Identification of a Late Onset Alzheimer's Disease Candidate Risk Variant at 9q21.33 in Polish Patients

(2018) Pawel Gaj et al.   JOURNAL OF ALZHEIMERS DISEASE

Racial and ethnic estimates of Alzheimer's disease and related dementias in the United States (2015–2060) in adults aged ≥65 years

(2018) Kevin A. Matthews et al.   Alzheimers & Dementia

Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease

(2018) Miia Kivipelto et al.   Nature Reviews Neurology

Comprehensive review of mechanisms of pathogenesis involved in Alzheimer’s disease and potential therapeutic strategies

(2018) Piyoosh Sharma et al.   PROGRESS IN NEUROBIOLOGY

Alzheimer's disease

(2017) C. A. Lane et al.   EUROPEAN JOURNAL OF NEUROLOGY

INPP5D mRNA Expression and Cognitive Decline in Japanese Alzheimer’s Disease Subjects

(2017) Yuta Yoshino et al.   JOURNAL OF ALZHEIMERS DISEASE

State of Play in Alzheimer’s Disease Genetics

(2017) Jin-Bao Zhu et al.   JOURNAL OF ALZHEIMERS DISEASE

The Role of ADAM10 in Alzheimer’s Disease

(2017) Xiang-Zhen Yuan et al.   JOURNAL OF ALZHEIMERS DISEASE

Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer’s Disease: The Role of APP

(2017) Eric Doran et al.   JOURNAL OF ALZHEIMERS DISEASE

The Ste20 Family Kinases MAP4K4, MINK1, and TNIK Converge to Regulate Stress-Induced JNK Signaling in Neurons

(2017) Martin Larhammar et al.   JOURNAL OF NEUROSCIENCE

Dementia prevention, intervention, and care

(2017) Gill Livingston et al.   LANCET

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

(2017) Rebecca Sims et al.   NATURE GENETICS

APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: A genetic screening study of familial and sporadic cases

(2017) Hélène-Marie Lanoiselée et al.   PLOS MEDICINE

Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism

(2016) Julien Chapuis et al.   ACTA NEUROPATHOLOGICA

Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease

(2016) Brian W. Kunkle et al.   Alzheimers & Dementia

Molecular genetics of early-onset Alzheimer's disease revisited

(2016) Rita Cacace et al.   Alzheimers & Dementia

Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology

(2016) Elizabeth E. Spangenberg et al.   BRAIN

Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology

(2016) P Dourlen et al.   MOLECULAR PSYCHIATRY

Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer’s disease with OSBPL6, PTPRG and PDCL3

(2016) C Herold et al.   MOLECULAR PSYCHIATRY

Profiling genome-wide DNA methylation

(2016) Wai-Shin Yong et al.   Epigenetics & Chromatin

ZCWPW1 is associated with late-onset Alzheimer&apos;s disease in Han Chinese: a replication study and meta-analyses

(2016) Yu Gao et al.   Oncotarget

ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease

(2016) Florent Letronne et al.   EBioMedicine

Inflammation in Alzheimer’s Disease and Molecular Genetics: Recent Update

(2015) Zhi-Gang Zhang et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis

(2015) Celeste M. Karch et al.   BIOLOGICAL PSYCHIATRY

Genetic differences among ethnic groups

(2015) Tao Huang et al.   BMC GENOMICS

The genetic landscape of Alzheimer disease: clinical implications and perspectives

(2015) Caroline Van Cauwenberghe et al.   GENETICS IN MEDICINE

A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

(2015) Tiia Ngandu et al.   LANCET

Blood type gene locus has no influence on ACE association with Alzheimer's disease

(2015) Anne Braae et al.   NEUROBIOLOGY OF AGING

A genome-wide association study of late-onset Alzheimer’s disease in a Japanese population

(2015) Atsushi Hirano et al.   PSYCHIATRIC GENETICS

Antagonistic Effects of BACE1 and APH1B-γ-Secretase Control Axonal Guidance by Regulating Growth Cone Collapse

(2015) Soraia Barão et al.   Cell Reports

PLXNA4is associated with Alzheimer disease and modulates tau phosphorylation

(2014) Gyungah Jun et al.   ANNALS OF NEUROLOGY

The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons

(2014) Christina R. Muratore et al.   HUMAN MOLECULAR GENETICS

CR1 in Alzheimer's Disease

(2014) Xi-Chen Zhu et al.   MOLECULAR NEUROBIOLOGY

PLD3 in Alzheimer’s Disease

(2014) Jun Wang et al.   MOLECULAR NEUROBIOLOGY

The Role of SORL1 in Alzheimer’s Disease

(2014) Rui-Hua Yin et al.   MOLECULAR NEUROBIOLOGY

ABCA7 in Alzheimer’s Disease

(2014) Qing-Fei Zhao et al.   MOLECULAR NEUROBIOLOGY

The Role of PICALM in Alzheimer’s Disease

(2014) Wei Xu et al.   MOLECULAR NEUROBIOLOGY

Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy

(2014) A. J. Westwood et al.   NEUROLOGY

PICALM modulates autophagy activity and tau accumulation

(2014) Kevin Moreau et al.   Nature Communications

Identifying genetic interactions associated with late-onset Alzheimer’s disease

(2014) Charalampos S Floudas et al.   BioData Mining

Cell autonomous regulation of hippocampal circuitry via Aph1b-γ-secretase/neuregulin 1 signalling

(2014) Pietro Fazzari et al.   eLife

The amyloid precursor protein: A biochemical enigma in brain development, function and disease

(2013) Natalia N. Nalivaeva et al.   FEBS LETTERS

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease

(2013) Carlos Cruchaga et al.   NATURE

Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

(2013) Ana Griciuc et al.   NEURON

GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease

(2013) Carlos Cruchaga et al.   NEURON

Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy

(2013) Y. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

(2013) B. B. Holmes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cognitive reserve in ageing and Alzheimer's disease

(2012) Yaakov Stern   LANCET NEUROLOGY

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genome-wide association study of Alzheimer's disease

(2012) M I Kamboh et al.   Translational Psychiatry

Cystatin C in Alzheimer's disease

(2012) Gurjinder Kaur et al.   Frontiers in Molecular Neuroscience

A Comprehensive Genetic Association Study of Alzheimer Disease in African Americans

(2011) Mark W. Logue   ARCHIVES OF NEUROLOGY

DNA methylation in neurodegenerative disorders: a missing link between genome and environment?

(2011) S Iraola-Guzmán et al.   CLINICAL GENETICS

Complement receptor 1 (CR1) and Alzheimer's disease

(2011) Helen Crehan et al.   IMMUNOBIOLOGY

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

Genome-Wide Association of Familial Late-Onset Alzheimer's Disease Replicates BIN1 and CLU and Nominates CUGBP2 in Interaction with APOE

(2011) Ellen M. Wijsman et al.   PLoS Genetics

The Revitalized Tau Hypothesis on Alzheimer's Disease

(2010) Ricardo B. Maccioni et al.   ARCHIVES OF MEDICAL RESEARCH

Identification of Novel Loci for Alzheimer Disease and Replication of CLU, PICALM, and BIN1 in Caribbean Hispanic Individuals

(2010) Joseph H. Lee et al.   ARCHIVES OF NEUROLOGY

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

(2010) Sudha Seshadri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Transcriptionally Active Amyloid Precursor Protein (APP) Intracellular Domain Is Preferentially Produced from the 695 Isoform of APP in a β-Secretase-dependent Pathway

(2010) Nikolai D. Belyaev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stimulation of glucose transport in osteoblastic cells by parathyroid hormone and insulin-like growth factor I

(2010) E. Zoidis et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Neuroimmunomodulation in the Pathogenesis of Alzheimer’s Disease

(2010) Inelia Morales et al.   NEUROIMMUNOMODULATION

Identification of independent APP locus duplication in Japanese patients with early-onset Alzheimer disease

(2009) K Kasuga et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Examination of the current top candidate genes for AD in a genome-wide association study

(2009) T M Feulner et al.   MOLECULAR PSYCHIATRY

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE

(2008) Lars Bertram et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cystatin C-Cathepsin B Axis Regulates Amyloid Beta Levels and Associated Neuronal Deficits in an Animal Model of Alzheimer's Disease

(2008) Binggui Sun et al.   NEURON