Alternative Splicing Regulation of an Alzheimer’s Risk Variant in CLU

Human Brain Region-Specific Alternative Splicing of TRPC3, the Type 3 Canonical Transient Receptor Potential Non-Selective Cation Channel

(2019) Jennie M. E. Cederholm et al.   CEREBELLUM

Precise temporal regulation of alternative splicing during neural development

(2018) Sebastien M. Weyn-Vanhentenryck et al.   Nature Communications

Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer’s disease susceptibility

(2018) Towfique Raj et al.   NATURE GENETICS

The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease

(2018) Minghui Wang et al.   Scientific Data

Altered splicing in Alzheimer transcriptomes

(2018) Linda Koch   NATURE REVIEWS GENETICS

Sex differences in metabolic aging of the brain: insights into female susceptibility to Alzheimer's disease

(2016) Liqin Zhao et al.   NEUROBIOLOGY OF AGING

Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts

(2016) Lin Tan et al.   Scientific Reports

Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases

(2016) Mariet Allen et al.   Scientific Data

Reduced secreted clusterin as a mechanism for Alzheimer-associated CLU mutations

(2015) Karolien Bettens et al.   Molecular Neurodegeneration

Alternative Splicing in the Mammalian Nervous System: Recent Insights into Mechanisms and Functional Roles

(2015) Bushra Raj et al.   NEURON

The Chaperone Activity of Clusterin is Dependent on Glycosylation and Redox Environment

(2014) Philipp Rohne et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Intracellular Clusterin Interacts with Brain Isoforms of the Bridging Integrator 1 and with the Microtubule-Associated Protein Tau in Alzheimer's Disease

(2014) Yuan Zhou et al.   PLoS One

rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data

(2014) Shihao Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

The Role of Clusterin in Alzheimer’s Disease: Pathways, Pathogenesis, and Therapy

(2012) Jin-Tai Yu et al.   MOLECULAR NEUROBIOLOGY

Variants Affecting Exon Skipping Contribute to Complex Traits

(2012) Younghee Lee et al.   PLoS Genetics

Alzheimer's risk variants in the clusterin gene are associated with alternative splicing

(2011) M Szymanski et al.   Translational Psychiatry

Analysis and design of RNA sequencing experiments for identifying isoform regulation

(2010) Yarden Katz et al.   NATURE METHODS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS