An APP ectodomain mutation outside of the Aβ domain promotes Aβ production in vitro and deposition in vivo

Negative evidence for a role of APH1B T27I variant in Alzheimer’s disease

(2020) Xulun Zhang et al.   HUMAN MOLECULAR GENETICS

Unraveling the complexity of γ-secretase

(2020) Michael S. Wolfe   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Identification of Novel Alzheimer’s Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data

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Sex-specific effects of microbiome perturbations on cerebral Aβ amyloidosis and microglia phenotypes

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Genetic and epigenetic study of an Alzheimer’s disease family with monozygotic triplets

(2019) Ming Zhang et al.   BRAIN

Phosphorylation Signaling in APP Processing in Alzheimer’s Disease

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Epitomic Characterization of the Specificity of the Anti-Amyloid Aβ Monoclonal Antibodies 6E10 and 4G8

(2018) Ibtisam Baghallab et al.   JOURNAL OF ALZHEIMERS DISEASE

Understanding the roles of mutations in the amyloid precursor protein in Alzheimer disease

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ClinVar: improving access to variant interpretations and supporting evidence

(2017) Melissa J Landrum et al.   NUCLEIC ACIDS RESEARCH

Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1ΔE9 murine model of Alzheimer’s disease

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Screening of dementia genes by whole-exome sequencing in early-onset Alzheimer disease: input and lessons

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A Synthetic Antibody Fragment Targeting Nicastrin Affects Assembly and Trafficking of γ-Secretase

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Exome sequencing identifies 2 novel presenilin 1 mutations (p.L166V and p.S230R) in British early-onset Alzheimer's disease

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Recent developments in the use of differential scanning fluorometry in protein and small molecule discovery and characterization

(2013) Anton Simeonov   Expert Opinion on Drug Discovery

Proline: The Distribution, Frequency, Positioning, and Common Functional Roles of Proline and Polyproline Sequences in the Human Proteome

(2013) Alexander A. Morgan et al.   PLoS One

Analysis of the Overall Structure of the Multi-Domain Amyloid Precursor Protein (APP)

(2013) Ina Coburger et al.   PLoS One

Trafficking and Proteolytic Processing of APP

(2013) C. Haass et al.   Cold Spring Harbor Perspectives in Medicine

Alzheimer Disease Aβ Production in the Absence ofS-Palmitoylation-dependent Targeting of BACE1 to Lipid Rafts

(2008) Kulandaivelu S. Vetrivel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elucidation of O-Glycosylation Structures of the β-Amyloid Precursor Protein by Liquid Chromatography−Mass Spectrometry Using Electron Transfer Dissociation and Collision Induced Dissociation

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