Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer’s disease

Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer’s disease risk genes

(2021) Jeremy Schwartzentruber et al.   NATURE GENETICS

γ-Secretase inhibitors and modulators: Mechanistic insights into the function and regulation of γ-Secretase

(2020) Pengju Nie et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The substrate repertoire of γ-secretase/presenilin

(2020) Gökhan Güner et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Association of blood-based transcriptional risk scores with biomarkers for Alzheimer disease

(2020) Young Ho Park et al.   Neurology-Genetics

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

(2019) Iris E. Jansen et al.   NATURE GENETICS

Blood amyloid-β oligomerization associated with neurodegeneration of Alzheimer’s disease

(2019) Young Chul Youn et al.   Alzheimers Research & Therapy

Dysregulated Fc gamma receptor–mediated phagocytosis pathway in Alzheimer's disease: network-based gene expression analysis

(2019) Young Ho Park et al.   NEUROBIOLOGY OF AGING

Genetics of Alzheimer’s disease: where we are, and where we are going

(2019) Céline Bellenguez et al.   CURRENT OPINION IN NEUROBIOLOGY

Modulation of γ- and β-Secretases as Early Prevention Against Alzheimer’s Disease

(2018) Iryna Voytyuk et al.   BIOLOGICAL PSYCHIATRY

Crucial role of protein oligomerization in the pathogenesis of Alzheimer's and Parkinson's diseases

(2018) Minee L. Choi et al.   FEBS Journal

The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects

(2018) Farhad Dehkhoda et al.   Frontiers in Endocrinology

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

A systemic view of Alzheimer disease — insights from amyloid-β metabolism beyond the brain

(2017) Jun Wang et al.   Nature Reviews Neurology

Small things matter: Implications of APP intracellular domain AICD nuclear signaling in the progression and pathogenesis of Alzheimer’s disease

(2017) Hassan Bukhari et al.   PROGRESS IN NEUROBIOLOGY

Oligomeric forms of amyloid-β protein in plasma as a potential blood-based biomarker for Alzheimer’s disease

(2017) Min Jeong Wang et al.   Alzheimers Research & Therapy

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

A reference panel of 64,976 haplotypes for genotype imputation

(2016)   NATURE GENETICS

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

(2016) Zhihong Zhu et al.   NATURE GENETICS

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function

(2016) Samuel E. Marsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer’s Disease Neuroimaging Initiative 2 Clinical Core: Progress and plans

(2015) Paul S. Aisen et al.   Alzheimers & Dementia

APOE effect on Alzheimer's disease biomarkers in older adults with significant memory concern

(2015) Shannon L. Risacher et al.   Alzheimers & Dementia

Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans

(2015) Andrew J. Saykin et al.   Alzheimers & Dementia

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Aberrant insulin signaling in Alzheimer's disease: current knowledge

(2015) Gaurav Bedse et al.   Frontiers in Neuroscience

Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology

(2014) Martina Sattlecker et al.   Alzheimers & Dementia

Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis

(2014) Petroula Proitsi et al.   PLOS MEDICINE

Bayesian method to predict individual SNP genotypes from gene expression data

(2012) Eric E Schadt et al.   NATURE GENETICS

Update on the Magnetic Resonance Imaging core of the Alzheimer's Disease Neuroimaging Initiative

(2010) Clifford R. Jack et al.   Alzheimers & Dementia

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

(2010) Yun Li et al.   GENETIC EPIDEMIOLOGY

Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS

(2010) Dan L. Nicolae et al.   PLoS Genetics

AddNeuroMed-The European Collaboration for the Discovery of Novel Biomarkers for Alzheimer's Disease

(2009) Simon Lovestone et al.   Annals of the New York Academy of Sciences

 -Secretase Heterogeneity in the Aph1 Subunit: Relevance for Alzheimer's Disease

(2009) L. Serneels et al.   SCIENCE

Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease

(2008) Alex E. Roher et al.   Alzheimers & Dementia

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

Growth hormone secretagogue MK-677: No clinical effect on AD progression in a randomized trial

(2008) J. J. Sevigny et al.   NEUROLOGY