PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer’s disease

Lysosomal Dysregulation in the Murine App Model of Alzheimer’s Disease

(2020) Lauren S. Whyte et al.   NEUROSCIENCE

PLD4 is a genetic determinant to systemic lupus erythematosus and involved in murine autoimmune phenotypes

(2019) Shuji Akizuki et al.   ANNALS OF THE RHEUMATIC DISEASES

Religious Orders Study and Rush Memory and Aging Project

(2018) David A. Bennett et al.   JOURNAL OF ALZHEIMERS DISEASE

A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease

(2018) Sara Mostafavi et al.   NATURE NEUROSCIENCE

Unconventional Trafficking of Mammalian Phospholipase D3 to Lysosomes

(2018) Adriana Carolina Gonzalez et al.   Cell Reports

OUP accepted manuscript

(2018)   BRAIN

PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing

(2018) Amanda L. Gavin et al.   NATURE IMMUNOLOGY

Harnessing Genetic Complexity to Enhance Translatability of Alzheimer’s Disease Mouse Models: A Path toward Precision Medicine

(2018) Sarah M. Neuner et al.   NEURON

PLD3 gene and processing of APP

(2017) Pietro Fazzari et al.   NATURE

Targeting phospholipase D in cancer, infection and neurodegenerative disorders

(2017) H. Alex Brown et al.   NATURE REVIEWS DRUG DISCOVERY

Progranulin, lysosomal regulation and neurodegenerative disease

(2017) Aimee W. Kao et al.   NATURE REVIEWS NEUROSCIENCE

rs2841277 (PLD4) is associated with susceptibility and rs4672495 is associated with disease activity in rheumatoid arthritis

(2017) Wei-Chiao Chen et al.   Oncotarget

The Relationship of Cerebral Vessel Pathology to Brain Microinfarcts

(2016) Zoe Arvanitakis et al.   BRAIN PATHOLOGY

PLD3 in Alzheimer’s Disease: a Modest Effect as Revealed by Updated Association and Expression Analyses

(2015) Deng-Feng Zhang et al.   MOLECULAR NEUROBIOLOGY

PLD3 variants in population studies

(2015) Sven J. van der Lee et al.   NATURE

PLD3 gene variants and Alzheimer's disease

(2015) Basavaraj V. Hooli et al.   NATURE

PLD3 and sporadic Alzheimer's disease risk

(2015) Jean-Charles Lambert et al.   NATURE

PLD3 in non-familial Alzheimer's disease

(2015) Stefanie Heilmann et al.   NATURE

Temporal course and pathologic basis of unawareness of memory loss in dementia

(2015) Robert S. Wilson et al.   NEUROLOGY

Cerebral amyloid angiopathy and cognitive outcomes in community-based older persons

(2015) Patricia A. Boyle et al.   NEUROLOGY

Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer’s disease amyloid plaques

(2015) Swetha Gowrishankar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Behavioral assays with mouse models of Alzheimer's disease: Practical considerations and guidelines

(2014) Daniela Puzzo et al.   BIOCHEMICAL PHARMACOLOGY

PLD3 is accumulated on neuritic plaques in Alzheimer’s disease brains

(2014) Jun-ichi Satoh et al.   Alzheimers Research & Therapy

Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models

(2014) Scott J. Webster et al.   Frontiers in Genetics

Overview and Findings from the Religious Orders Study

(2013) David A. Bennett et al.   Current Alzheimer Research

Overview and Findings from the Rush Memory and Aging Project

(2013) David A. Bennett et al.   Current Alzheimer Research

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease

(2013) Carlos Cruchaga et al.   NATURE

The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis

(2012) Jonathan J. Ipsaro et al.   NATURE

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population

(2012) Yukinori Okada et al.   NATURE GENETICS

A Role for Phospholipase D3 in Myotube Formation

(2012) Mary Osisami et al.   PLoS One

Microinfarct Pathology, Dementia, and Cognitive Systems

(2011) Zoe Arvanitakis et al.   STROKE

Cerebrovascular Disease Pathology and Parkinsonian Signs in Old Age

(2011) Aron S. Buchman et al.   STROKE