The Neurovascular Unit Dysfunction in Alzheimer’s Disease

(-)-Epigallocatechin-3-gallate provides neuroprotection via AMPK activation against traumatic brain injury in a mouse model

(2020) Yinyin Wu et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Effector function of anti-pyroglutamate-3 Aβ antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer’s-like mice

(2020) Helen Crehan et al.   Alzheimers Research & Therapy

Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer's Disease

(2020) Raymond S. Turner et al.   ANNALS OF NEUROLOGY

Preclinical and clinical studies on bryostatins, a class of marine-derived protein kinase C modulators: A mini-review

(2020) Rinky Raghuvanshi et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Understanding the Pathophysiology of Cerebral Amyloid Angiopathy

(2020) Laura Gatti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Haplotype of the astrocytic water channel AQP4 is associated with slow wave energy regulation in human NREM sleep

(2020) Sara Marie Ulv Larsen et al.   PLOS BIOLOGY

Neurovascular Unit Dysfunction and Neurodegenerative Disorders

(2020) Xing Yu et al.   Frontiers in Neuroscience

Interactions between Amyloid-Β Proteins and Human Brain Pericytes: Implications for the Pathobiology of Alzheimer’s Disease

(2020) Donald J. Alcendor   Journal of Clinical Medicine

Glymphatic failure as a final common pathway to dementia

(2020) Maiken Nedergaard et al.   SCIENCE

Corrigendum: Anakinra Therapy for Non-cancer Inflammatory Diseases

(2019) Giulio Cavalli et al.   Frontiers in Pharmacology

Innovative Therapy for Alzheimer’s Disease-With Focus on Biodelivery of NGF

(2019) Sumonto Mitra et al.   Frontiers in Neuroscience

Drug Development for Alzheimer’s Disease: Microglia Induced Neuroinflammation as a Target?

(2019) Yuan Dong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Target Engagement in an Alzheimer Trial: Crenezumab Lowers Aβ Oligomers in CSF

(2019) Ting Yang et al.   ANNALS OF NEUROLOGY

Effect of Different Classes of Antihypertensive Drugs on Endothelial Function and Inflammation

(2019) Isabella Viana Gomes Silva et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Interaction of natural compounds with biomembrane models: A biophysical approach for the Alzheimer’s disease therapy

(2019) Stephanie Andrade et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Nanotechnology to improve the Alzheimer’s disease therapy with natural compounds

(2019) Maria João Ramalho et al.   Drug Delivery and Translational Research

Complement Receptor 1 (CR1, CD35) Polymorphisms and Soluble CR1: A Proposed Anti-inflammatory Role to Quench the Fire of “Fogo Selvagem” Pemphigus Foliaceus

(2019) Luana Caroline Oliveira et al.   Frontiers in Immunology

Cerebral amyloid angiopathy and Alzheimer disease — one peptide, two pathways

(2019) Steven M. Greenberg et al.   Nature Reviews Neurology

An Overview on the Clinical Development of Tau-Based Therapeutics

(2018) Miguel Medina   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Memantine for the Treatment of Dementia: A Review on its Current and Future Applications

(2018) Jaume Folch et al.   JOURNAL OF ALZHEIMERS DISEASE

Role of Blood-Brain Barrier in Alzheimer’s Disease

(2018) Zhiyou Cai et al.   JOURNAL OF ALZHEIMERS DISEASE

The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death

(2018) Sofia Söllvander et al.   Journal of Neuroinflammation

Tau-targeting therapies for Alzheimer disease

(2018) Erin E. Congdon et al.   Nature Reviews Neurology

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

Una revisión de los avances en la terapéutica de la enfermedad de Alzheimer: estrategia frente a la proteína β-amiloide

(2018) J. Folch et al.   NEUROLOGIA

TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function

(2018) Yingjun Zhao et al.   NEURON

Microglial Activation Is Modulated by Captopril: in Vitro and in Vivo Studies

(2018) Keren Asraf et al.   Frontiers in Cellular Neuroscience

Traumatic Brain Injury and Alzheimer's Disease: The Cerebrovascular Link

(2018) Jaime Ramos-Cejudo et al.   EBioMedicine

Anti-α4β1 integrin antibodies attenuated brain inflammatory changes in a mouse model of Alzheimer’s disease

(2018) Colin Combs et al.   Current Alzheimer Research

Brain Pericytes ABCA1 Expression Mediates Cholesterol Efflux but not Cellular Amyloid-β Peptide Accumulation

(2018) Julien Saint-Pol et al.   JOURNAL OF ALZHEIMERS DISEASE

Neurovascular Defects and Faulty Amyloid-β Vascular Clearance in Alzheimer's Disease

(2018) Abhay P. Sagare et al.   JOURNAL OF ALZHEIMERS DISEASE

Modulation of α7 Nicotinic Acetylcholine Receptor and Fibrillar Amyloid-β Interactions in Alzheimer's Disease Brain

(2018) Ruiqing Ni et al.   JOURNAL OF ALZHEIMERS DISEASE

Neurovascular dysfunction in vascular dementia, Alzheimer’s and atherosclerosis

(2018) Osman Shabir et al.   BMC NEUROSCIENCE

Pharmacokinetics and Pharmacodynamics of the BACE1 Inhibitor Verubecestat (MK-8931) in Healthy Japanese Adults: A Randomized, Placebo-Controlled Study

(2018) K. Chris Min et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Liposome delivery systems for the treatment of Alzheimer’s disease

(2018) Callum Ross et al.   International Journal of Nanomedicine

Combined treatment with the phenolics (−)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces Alzheimer-like pathology in mice

(2018) Takashi Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The glymphatic pathway in neurological disorders

(2018) Martin Kaag Rasmussen et al.   LANCET NEUROLOGY

Complement protein C5a enhances the β-amyloid-induced neuro-inflammatory response in microglia in Alzheimer’s disease

(2018) Xiao-qun An et al.   M S-MEDECINE SCIENCES

Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism

(2018) Qingyi Ma et al.   Molecular Neurodegeneration

Nanotechnology-mediated crossing of two impermeable membranes to modulate the stars of the neurovascular unit for neuroprotection

(2018) Bapurao Surnar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SAR228810: an antibody for protofibrillar amyloid β peptide designed to reduce the risk of amyloid-related imaging abnormalities (ARIA)

(2018) Laurent Pradier et al.   Alzheimers Research & Therapy

Blood-Brain Barrier Dysfunction and the Pathogenesis of Alzheimer’s Disease

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

VEGFR1 and VEGFR2 in Alzheimer’s Disease

(2017) Rachel Harris et al.   JOURNAL OF ALZHEIMERS DISEASE

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

A fluoro-Nissl dye identifies pericytes as distinct vascular mural cells during in vivo brain imaging

(2017) Eyiyemisi C Damisah et al.   NATURE NEUROSCIENCE

Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease

(2017) Kassandra Kisler et al.   NATURE REVIEWS NEUROSCIENCE

The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease

(2017) Costantino Iadecola   NEURON

Evidence for benefit of statins to modify cognitive decline and risk in Alzheimer’s disease

(2017) Nophar Geifman et al.   Alzheimers Research & Therapy

Association of Perivascular Localization of Aquaporin-4 With Cognition and Alzheimer Disease in Aging Brains

(2017) Douglas M. Zeppenfeld et al.   JAMA Neurology

The Pathophysiological Role of Microglia in Dynamic Surveillance, Phagocytosis and Structural Remodeling of the Developing CNS

(2017) Cataldo Arcuri et al.   Frontiers in Molecular Neuroscience

The role of insulin in the vascular contributions to age-related dementia

(2016) Timothy M. Hughes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease

(2016) Amy R. Nelson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Lymphatic Clearance of the Brain: Perivascular, Paravascular and Significance for Neurodegenerative Diseases

(2016) Erik N. T. P. Bakker et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Two Phase 2 Multiple Ascending–Dose Studies of Vanutide Cridificar (ACC-001) and QS-21 Adjuvant in Mild-to-Moderate Alzheimer’s Disease

(2016) Florence Pasquier et al.   JOURNAL OF ALZHEIMERS DISEASE

Drug delivery of the future: Chasing the invisible gorilla

(2016) Kinam Park   JOURNAL OF CONTROLLED RELEASE

Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases

(2016) Cláudia Saraiva et al.   JOURNAL OF CONTROLLED RELEASE

Neuroinflammation: the devil is in the details

(2016) Damon J. DiSabato et al.   JOURNAL OF NEUROCHEMISTRY

Memantine mediates neuroprotection via regulating neurovascular unit in a mouse model of focal cerebral ischemia

(2016) Zheng-Zhen Chen et al.   LIFE SCIENCES

Functions and mechanisms of microglia/macrophages in neuroinflammation and neurogenesis after stroke

(2016) Xiao-Yi Xiong et al.   PROGRESS IN NEUROBIOLOGY

Cerebral vascular amyloid seeds drive amyloid β-protein fibril assembly with a distinct anti-parallel structure

(2016) Feng Xu et al.   Nature Communications

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models

(2016) Michael J. D. Daniels et al.   Nature Communications

Current Research Therapeutic Strategies for Alzheimer’s Disease Treatment

(2016) Jaume Folch et al.   NEURAL PLASTICITY

Analysis of the Putative Role of CR1 in Alzheimer’s Disease: Genetic Association, Expression and Function

(2016) Maria I. Fonseca et al.   PLoS One

Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models

(2015) Valeria Melis et al.   BEHAVIOURAL PHARMACOLOGY

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

Dexamethasone Potentiates in Vitro Blood-Brain Barrier Recovery after Primary Blast Injury by Glucocorticoid Receptor-Mediated Upregulation of ZO-1 Tight Junction Protein

(2015) Christopher D Hue et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Ion channel networks in the control of cerebral blood flow

(2015) Thomas A Longden et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Tonic Local Brain Blood Flow Control by Astrocytes Independent of Phasic Neurovascular Coupling

(2015) D. G. Rosenegger et al.   JOURNAL OF NEUROSCIENCE

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Clearance systems in the brain—implications for Alzheimer disease

(2015) Jenna M. Tarasoff-Conway et al.   Nature Reviews Neurology

The Glymphatic System: A Beginner’s Guide

(2015) Nadia Aalling Jessen et al.   NEUROCHEMICAL RESEARCH

Cerebral Hypoperfusion-Assisted Intra-arterial Deposition of Liposomes in Normal and Glioma-Bearing Rats

(2015) Shailendra Joshi et al.   NEUROSURGERY

The Blood–Brain Barrier

(2015) Richard Daneman et al.   Cold Spring Harbor Perspectives in Biology

Targeting Prodromal Alzheimer Disease With Avagacestat

(2015) Vladimir Coric et al.   JAMA Neurology

The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease

(2015) Josiane Budni et al.   Aging and Disease

Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy

(2015) Laura J Blair et al.   Acta Neuropathologica Communications

First Administration of the Fc-Attenuated Anti-β Amyloid Antibody GSK933776 to Patients with Mild Alzheimer’s Disease: A Randomized, Placebo-Controlled Study

(2015) Niels Andreasen et al.   PLoS One

The neurovascular unit - concept review

(2014) V. Muoio et al.   Acta Physiologica

Lenti-GDNF Gene Therapy Protects Against Alzheimer's Disease-Like Neuropathology in 3xTg-AD Mice and MC65 Cells

(2014) Susana Revilla et al.   CNS Neuroscience & Therapeutics

Pial Arteries Respond Earlier than Penetrating Arterioles to Neural Activation in the Somatosensory Cortex in Awake Mice Exposed to Chronic Hypoxia: An Additional Mechanism to Proximal Integration Signaling?

(2014) Yuta Sekiguchi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Age-Dependent, Non-Cell-Autonomous Deposition of Amyloid from Synthesis of  -Amyloid by Cells Other Than Excitatory Neurons

(2014) K. Veeraraghavalu et al.   JOURNAL OF NEUROSCIENCE

Angiotensin II type 1 receptor blocker losartan prevents and rescues cerebrovascular, neuropathological and cognitive deficits in an Alzheimer’s disease model

(2014) Brice Ongali et al.   NEUROBIOLOGY OF DISEASE

First-in-man tau vaccine targeting structural determinants essential for pathological tau–tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer’s disease model

(2014) Eva Kontsekova et al.   Alzheimers Research & Therapy

BACE1 inhibitor drugs in clinical trials for Alzheimer’s disease

(2014) Robert Vassar   Alzheimers Research & Therapy

Alzheimer’s disease: relevant molecular and physiopathological events affecting amyloid-β brain balance and the putative role of PPARs

(2014) Juan M. Zolezzi et al.   Frontiers in Aging Neuroscience

Insulin as a Bridge between Type 2 Diabetes and Alzheimer Disease – How Anti-Diabetics Could be a Solution for Dementia

(2014) Inês Sebastião et al.   Frontiers in Endocrinology

γ-Secretase inhibitors and modulators

(2013) Todd E. Golde et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The effect of cationic albumin-conjugated PEGylated tanshinone IIA nanoparticles on neuronal signal pathways and neuroprotection in cerebral ischemia

(2013) Xin Liu et al.   BIOMATERIALS

Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice

(2013) Sandra Sivilia et al.   BMC NEUROSCIENCE

Calcium channel blockers and dementia

(2013) V Nimmrich et al.   BRITISH JOURNAL OF PHARMACOLOGY

Vascular Risk Factors and Neurodegeneration in Ageing Related Dementias: Alzheimer’s Disease and Vascular Dementia

(2013) Rufus Akinyemi et al.   Current Alzheimer Research

On the Interaction of β-Amyloid Peptides and α7-Nicotinic Acetylcholine Receptors in Alzheimer’s Disease

(2013) Murat Oz et al.   Current Alzheimer Research

Layer-Specific Dilation of Penetrating Arteries Induced by Stimulation of the Nucleus Basalis of Meynert in the Mouse Frontal Cortex

(2013) Harumi Hotta et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Blood–Brain Barrier Dysfunction as a Cause and Consequence of Alzheimer's Disease

(2013) Michelle A Erickson et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Intravenous immunoglobulin and Alzheimer’s disease: what now?

(2013) David A Loeffler   Journal of Neuroinflammation

Immunotherapy for Alzheimer’s disease: hoops and hurdles

(2013) Cynthia A Lemere   Molecular Neurodegeneration

The Pathobiology of Vascular Dementia

(2013) Costantino Iadecola   NEURON

Claudins and the Modulation of Tight Junction Permeability

(2013) Dorothee Günzel et al.   PHYSIOLOGICAL REVIEWS

Pioglitazone Improves Reversal Learning and Exerts Mixed Cerebrovascular Effects in a Mouse Model of Alzheimer’s Disease with Combined Amyloid-β and Cerebrovascular Pathology

(2013) Panayiota Papadopoulos et al.   PLoS One

VEGF significantly restores impaired memory behavior in Alzheimer's mice by improvement of vascular survival

(2013) Piotr Religa et al.   Scientific Reports

Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain

(2013) Vinita Rangroo Thrane et al.   Scientific Reports

Neurovascular Dysfunction and Faulty Amyloid  -Peptide Clearance in Alzheimer Disease

(2013) A. P. Sagare et al.   Cold Spring Harbor Perspectives in Medicine

Protective effects of cationic bovine serum albumin-conjugated PEGylated tanshinone IIA nanoparticles on cerebral ischemia

(2012) Xin Liu et al.   BIOMATERIALS

Angiotensin II AT1receptor blockers as treatments for inflammatory brain disorders

(2012) Juan M. Saavedra   CLINICAL SCIENCE

Overview and introduction: The blood-brain barrier in health and disease

(2012) N. Joan Abbott et al.   EPILEPSIA

Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia

(2012) Hongjun Fu et al.   GLIA

Trans-cellular Propagation of Tau Aggregation by Fibrillar Species

(2012) Najla Kfoury et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

(2012) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

Age-Dependent Rescue by Simvastatin of Alzheimer's Disease Cerebrovascular and Memory Deficits

(2012) X.-K. Tong et al.   JOURNAL OF NEUROSCIENCE

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

The many faces of insulin-like peptide signalling in the brain

(2012) Ana M. Fernandez et al.   NATURE REVIEWS NEUROSCIENCE

Neuroinflammation and Blood-Brain Barrier Changes in Capillary Amyloid Angiopathy

(2012) Anna Carrano et al.   Neurodegenerative Diseases

Morphological and Pathological Evolution of the Brain Microcirculation in Aging and Alzheimer’s Disease

(2012) Jesse M. Hunter et al.   PLoS One

Rosiglitazone and Pioglitazone for the Treatment of Alzheimer's Disease

(2011) Benjamin W Miller et al.   ANNALS OF PHARMACOTHERAPY

Intranasal Insulin Therapy for Alzheimer Disease and Amnestic Mild Cognitive Impairment

(2011) Suzanne Craft   ARCHIVES OF NEUROLOGY

Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: The case for isradipine

(2011) Thimmappa S. Anekonda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Fatty acids acutely enhance insulin-induced oxidative stress and cause insulin resistance by increasing mitochondrial reactive oxygen species (ROS) generation and nuclear factor-κB inhibitor (IκB)–nuclear factor-κB (NFκB) activation in rat muscle, in the absence of mitochondrial dysfunction

(2011) R. Barazzoni et al.   DIABETOLOGIA

Solanezumab for Alzheimer's disease

(2011) Hossein Samadi et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain

(2011) Allal Boutajangout et al.   JOURNAL OF NEUROCHEMISTRY

Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity

(2011) Dan Zhang et al.   Journal of Neuroinflammation

Neurovascular dysfunction, inflammation and endothelial activation: Implications for the pathogenesis of Alzheimer's disease

(2011) Paula Grammas   Journal of Neuroinflammation

Central nervous system pericytes in health and disease

(2011) Ethan A Winkler et al.   NATURE NEUROSCIENCE

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

(2011) Berislav V. Zlokovic   NATURE REVIEWS NEUROSCIENCE

Mechanism mediating oligomeric Aβ clearance by naïve primary microglia

(2011) Cheng-Ning Yang et al.   NEUROBIOLOGY OF DISEASE

HI 6 human serum albumin nanoparticles—Development and transport over an in vitro blood–brain barrier model

(2011) Miriam Dadparvar et al.   TOXICOLOGY LETTERS

PF-04494700, an Oral Inhibitor of Receptor for Advanced Glycation End Products (RAGE), in Alzheimer Disease

(2010) Marwan N. Sabbagh et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Hereditary Cerebral Hemorrhage With Amyloidosis Associated With the E693K Mutation of APP

(2010) Orso Bugiani et al.   ARCHIVES OF NEUROLOGY

Tarenflurbil

(2010) Mary Sano   ARCHIVES OF NEUROLOGY

ABC efflux transporters in brain vasculature of Alzheimer's subjects

(2010) Hasini C. Wijesuriya et al.   BRAIN RESEARCH

Selective targeting of a TNFR decoy receptor pharmaceutical to the primate brain as a receptor-specific IgG fusion protein

(2010) Ruben J. Boado et al.   JOURNAL OF BIOTECHNOLOGY

Microglial C5aR (CD88) expression correlates with amyloid-β deposition in murine models of Alzheimer’s disease

(2010) Rahasson R. Ager et al.   JOURNAL OF NEUROCHEMISTRY

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

Review: Sporadic cerebral amyloid angiopathy

(2010) J. Attems et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Targeting the neurovascular unit for treatment of neurological disorders

(2010) Reyna L. VanGilder et al.   PHARMACOLOGY & THERAPEUTICS

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Neurovascular mechanisms and blood–brain barrier disorder in Alzheimer’s disease

(2009) Robert D. Bell et al.   ACTA NEUROPATHOLOGICA

Contribution of hypoxia to Alzheimer’s disease: is HIF-1α a mediator of neurodegeneration?

(2009) O. O. Ogunshola et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Immunotherapy, Vascular Pathology, and Microhemorrhages in Transgenic Mice

(2009) Donna Wilcock et al.   CNS & Neurological Disorders-Drug Targets

Development of semagacestat (LY450139), a functional γ-secretase inhibitor, for the treatment of Alzheimer's disease

(2009) David B Henley et al.   EXPERT OPINION ON PHARMACOTHERAPY

A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia

(2009) Christine L. Hsieh et al.   JOURNAL OF NEUROCHEMISTRY

CD14 and Toll-Like Receptors 2 and 4 Are Required for Fibrillar A -Stimulated Microglial Activation

(2009) E. G. Reed-Geaghan et al.   JOURNAL OF NEUROSCIENCE

A Nanomedicine Transports a Peptide Caspase-3 Inhibitor across the Blood-Brain Barrier and Provides Neuroprotection

(2009) H. Karatas et al.   JOURNAL OF NEUROSCIENCE

Evidence of carrier‐mediated transport in the penetration of donepezil into the rat brain

(2009) Mi‐Hwa Kim et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Matrix metalloproteinases and their multiple roles in neurodegenerative diseases

(2009) Gary A Rosenberg   LANCET NEUROLOGY

Alzheimer's disease

(2009) Lennart Mucke   NATURE

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

Risk of dementia and AD with prior exposure to NSAIDs in an elderly community-based cohort

(2009) J.C.S. Breitner et al.   NEUROLOGY

Targeting Extracellular Matrix Proteolysis for Hemorrhagic Complications of tPA Stroke Therapy

(2008) Xiaoying Wang et al.   CNS & Neurological Disorders-Drug Targets

The role of adherens junctions and VE-cadherin in the control of vascular permeability

(2008) E. Dejana et al.   JOURNAL OF CELL SCIENCE

Complete Rescue of Cerebrovascular Function in Aged Alzheimer's Disease Transgenic Mice by Antioxidants and Pioglitazone, a Peroxisome Proliferator-Activated Receptor   Agonist

(2008) N. Nicolakakis et al.   JOURNAL OF NEUROSCIENCE

Cerebrovascular Dysfunction in Amyloid Precursor Protein Transgenic Mice: Contribution of Soluble and Insoluble Amyloid-  Peptide, Partial Restoration via  -Secretase Inhibition

(2008) B. H. Han et al.   JOURNAL OF NEUROSCIENCE

SRF and myocardin regulate LRP-mediated amyloid-β clearance in brain vascular cells

(2008) Robert D. Bell et al.   NATURE CELL BIOLOGY

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Amyloid beta oligomers induce impairment of neuronal insulin receptors

(2007) Wei-Qin Zhao et al.   FASEB JOURNAL