Synthetic α-glucosidase inhibitors as promising anti-diabetic agents: Recent developments and future challenges

Synthesis, Molecular Docking and Biological Evaluation of 5‐Alkyl (aryl)‐2‐isobutylthiazole Derivatives: As α‐amylase, α‐Glucosidase, and Protein Kinase Inhibitors

(2022) Siraj Khan et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Recent advances in the synthetic method and mechanism for the important N‐heterocyclic compound of 3‐methylindole

(2022) Yi Fu et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Synthesis of 2-styryl-quinazoline and 3-styryl-quinoxaline based sulfonate esters via sp3 C-H activation and their evaluation for α-glucosidase inhibition

(2022) Neeli Satyanarayana et al.   NEW JOURNAL OF CHEMISTRY

Synthesis, In‐Vitro Evaluation and Molecular Docking Study of N‐Substituted Thiazolidinediones as α‐Glucosidase Inhibitors

(2022) Vijay M. Patil et al.   ChemistrySelect

Isatin thiazoles as antidiabetic: Synthesis, in vitro enzyme inhibitory activities, kinetics, and in silico studies

(2022) Mehwish Solangi et al.   ARCHIV DER PHARMAZIE

In silico and in vitro studies of thiosemicarbazone-indole hybrid compounds as potent α-glycosidase inhibitors

(2022) Zohreh Bakherad et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

A review on synthesis, mechanism of action, and structure-activity relationships of 1,2,3-triazole-based α-glucosidase inhibitors as promising anti-diabetic agents

(2022) Zari Fallah et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis of 1,2,3-benzotriazin-4(3H)-one derivatives as α-glucosidase inhibitor and their in-silico study

(2022) Zunera Khalid et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis, α-glucosidase inhibition, α-amylase inhibition, and molecular docking studies of 3,3-di(indolyl)indolin-2-ones

(2022) Mardi Santoso et al.   Heliyon

Mercaptobenzimidazole-Based 1,3-Thaizolidin-4-ones as Antidiabetic Agents: Synthesis, In Vitro α-Glucosidase Inhibition Activity, and Molecular Docking Studies

(2022) Sher Ali Khan et al.   ACS Omega

Flavone-1,2,3-triazole derivatives as potential α-glucosidase inhibitors: Synthesis, enzyme inhibition, kinetic analysis and molecular docking study

(2022) Manoj Dhameja et al.   BIOORGANIC CHEMISTRY

Synthesis and biological evaluation of coumarin derivatives containing oxime ester as α-glucosidase inhibitors

(2022) Xin Zhang et al.   Arabian Journal of Chemistry

Synthesis, molecular docking study of thiazole derivatives and exploring their dual inhibitor potentials against α-amylase and α-glucosidase

(2022) Hayat Ullah et al.   Chemical Data Collections

2,5-Disubstituted furan derivatives containing imidazole, triazole or tetrazole moiety as potent α-glucosidase inhibitors

(2022) Min He et al.   BIOORGANIC CHEMISTRY

Synthesis, in vitro, and in silico studies of newly functionalized quinazolinone analogs for the identification of potent α-glucosidase inhibitors

(2021) Hayat Wali et al.   Journal of the Iranian Chemical Society

α-Glucosidase and α-amylase inhibition, molecular modeling and pharmacokinetic studies of new quinazolinone-1,2,3-triazole-acetamide derivatives

(2021) Ali Yavari et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis of indole-based-thiadiazole derivatives as a potent inhibitor of α-glucosidase enzyme along with in silico study

(2021) Munther Alomari et al.   BIOORGANIC CHEMISTRY

Evaluation and docking of indole sulfonamide as a potent inhibitor of α-glucosidase enzyme in Streptozotocin -induced diabetic albino Wistar rats

(2021) Muhammad Taha et al.   BIOORGANIC CHEMISTRY

Synthesis and studies of thiazolidinedione–isatin hybrids as α-glucosidase inhibitors for management of diabetes

(2021) Ramandeep Kaur et al.   Future Medicinal Chemistry

Design and Synthesis of Fluoroquinolone Derivatives as Potent α‐Glucosidase Inhibitors: In Vitro Inhibitory Screening with In Silico Docking Studies

(2021) Aasia Shaheen et al.   ChemistrySelect

New quinoxalin‐1,3,4‐oxadiazole derivatives: Synthesis, characterization, in vitro biological evaluations, and molecular modeling studies

(2021) Roghieh Mirzazadeh et al.   ARCHIV DER PHARMAZIE

Synthesis, in-vitro evaluation, molecular docking, and kinetic studies of pyridazine-triazole hybrid system as novel α-glucosidase inhibitors

(2021) Setareh Moghimi et al.   BIOORGANIC CHEMISTRY

Synthesis, in vitro and in silico enzymatic inhibition assays, and toxicity evaluations of new 4,5-diphenylimidazole-N-phenylacetamide derivatives as potent α-glucosidase inhibitors

(2021) Maryam Mohammadi-Khanaposhtani et al.   MEDICINAL CHEMISTRY RESEARCH

Design, synthesis, and α‐glucosidase‐inhibitory activity of phenoxy‐biscoumarin –N ‐phenylacetamide hybrids

(2021) Samira Ansari et al.   ARCHIV DER PHARMAZIE

Synthesis of novel 5-(2,5-bis(2,2,2-trifluoroethoxy)phenyl)-1,3,4-oxadiazole-2-thiol derivatives as potential glucosidase inhibitors

(2021) Ramesh S. Gani et al.   BIOORGANIC CHEMISTRY

A facile approach synthesis of benzoylaryl benzimidazole as potential α-amylase and α-glucosidase inhibitor with antioxidant activity

(2021) Lotfi M. Aroua et al.   BIOORGANIC CHEMISTRY

Design and synthesis of novel quinazolinone-pyrazole derivatives as potential α-glucosidase inhibitors: Structure-activity relationship, molecular modeling and kinetic study

(2021) Fateme Azimi et al.   BIOORGANIC CHEMISTRY

Biological evaluation the 2‐aryl‐2,3‐dihydrobenzodiazaborinin‐4(1 H )‐ones as potential dual α‐glucosidase and α‐amylase inhibitors with antioxidant properties

(2021) Malose J. Mphahlele et al.   Chemical Biology & Drug Design

Benzoxazolyl linked benzylidene based rhodanine and analogs as novel antidiabetic agents: synthesis, molecular docking, and in vitro studies

(2021) Varinder Singh et al.   MEDICINAL CHEMISTRY RESEARCH

Design, synthesis, molecular docking, and in vitro α-glucosidase inhibitory activities of novel 3-amino-2,4-diarylbenzo[4,5]imidazo[1,2-a]pyrimidines against yeast and rat α-glucosidase

(2021) Fariba Peytam et al.   Scientific Reports

Towards multi-target antidiabetic agents: In vitro and in vivo evaluation of 3,5-disubstituted indolin-2-one derivatives as novel α-glucosidase inhibitors

(2021) Vladlen G. Klochkov et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Isatin-hydrazide conjugates as potent α-amylase and α-glucosidase inhibitors: Synthesis, structure and in vitro evaluations

(2021) Inzamam Abbasi et al.   BIOORGANIC CHEMISTRY

Synthesis of new clioquinol derivatives as potent α-glucosidase inhibitors; molecular docking, kinetic and structure–activity relationship studies

(2021) Shoukat Wali et al.   BIOORGANIC CHEMISTRY

New biologically dynamic hybrid pharmacophore triazinoindole-based-thiadiazole as potent α-glucosidase inhibitors: In vitro and in silico study

(2021) Aftab Ahmad Khan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Synthesis of indole derivatives as diabetics II inhibitors and enzymatic kinetics study of α-glucosidase and α-amylase along with their in-silico study

(2021) Muhammad Taha et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Design and synthesis of new benzylidene-quinazolinone hybrids as potential anti-diabetic agents: In vitro α-glucosidase inhibition, and docking studies

(2021) Mohamed M. Khalifa et al.   JOURNAL OF MOLECULAR STRUCTURE

Design, synthesis, biological evaluations and in silico studies of sulfonate ester derivatives of 2-(2-benzylidenehydrazono)thiazolidin-4-one as potential α-glucosidase inhibitors

(2021) Ramandeep Kaur et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis of 7-azaindole based carbohydrazides and 1,3,4-oxadiazoles; Antioxidant activity, α-glucosidase inhibition properties and docking study

(2021) Samet Izgi et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, crystal structure, DFT, α-glucosidase and α-amylase inhibition and molecular docking studies of (E)-N'-(4-chlorobenzylidene)-5-phenyl-1H-pyrazole-3-carbohydrazide

(2021) Khalid Karrouchi et al.   JOURNAL OF MOLECULAR STRUCTURE

Design, biological evaluation, molecular docking study and in silico ADME prediction of novel imidazo[2,1-b]thiazole derivatives as a novel class of α-glucosidase inhibitors

(2021) Efe Doğukan Dincel et al.   JOURNAL OF MOLECULAR STRUCTURE

One-pot multi-component synthesis of novel chromeno[4,3-b]pyrrol-3-yl derivatives as alpha-glucosidase inhibitors

(2021) Malihe Karami et al.   MOLECULAR DIVERSITY

Design, synthesis, biological evaluation, and molecular modeling studies of pyrazole-benzofuran hybrids as new α-glucosidase inhibitor

(2021) Fateme Azimi et al.   Scientific Reports

Exploring the therapeutic potential of benzothiazine-pyrazole hybrid molecules against alpha-glucosidase: Pharmacological and molecular modelling based approach

(2021) Saman Taj et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Anti-diabetic drugs recent approaches and advancements

(2020) Jayanta Dowarah et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Dihydropyridines as potential α-amylase and α-glucosidase inhibitors: Synthesis, in vitro and in silico studies

(2020) Hina Yousuf et al.   BIOORGANIC CHEMISTRY

Discovery of novel pyrido-pyrrolidine hybrid compounds as alpha-glucosidase inhibitors and alternative agent for control of type 1 diabetes

(2020) Tania Luthra et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Green synthesis of diethyl((2-iodo-4-(trifluoromethyl)phenyl)amino)(aryl)methyl)phosphonates as potent α-glucosidase inhibitors

(2020) Mahammad Sadik Shaik et al.   SYNTHETIC COMMUNICATIONS

Aryl-oxadiazole Schiff bases: Synthesis, α-glucosidase in vitro inhibitory activity and their in silico studies

(2020) Hayat Ullah et al.   Arabian Journal of Chemistry

An efficient and targeted synthetic approach towards new highly substituted 6-amino-pyrazolo[1,5-a]pyrimidines with α-glucosidase inhibitory activity

(2020) Fariba Peytam et al.   Scientific Reports

Study on the interaction of triaryl-dihydro-1,2,4-oxadiazoles with α-glucosidase

(2020) Arefeh Khosravi et al.   DARU-Journal of Pharmaceutical Sciences

A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications

(2020) Nagaraju Kerru et al.   MOLECULES

Syntheses, in vitro α-amylase and α-glucosidase dual inhibitory activities of 4-amino-1,2,4-triazole derivatives their molecular docking and kinetic studies

(2020) Emmanuel Oloruntoba Yeye et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and screening of (E)-3-(2-benzylidenehydrazinyl)-5,6-diphenyl-1,2,4-triazine analogs as novel dual inhibitors of α-amylase and α-glucosidase

(2020) Shahbaz Shamim et al.   BIOORGANIC CHEMISTRY

Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs

(2020) Nebih Lolak et al.   BIOORGANIC CHEMISTRY

New acridine-9-carboxamide linked to 1,2,3-triazole-N-phenylacetamide derivatives as potent α-glucosidase inhibitors: design, synthesis, in vitro, and in silico biological evaluations

(2020) Nima Sepehri et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis, α-glucosidase inhibition, and molecular docking studies of novel N-substituted hydrazide derivatives of atranorin as antidiabetic agents

(2020) Thuc-Huy Duong et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design and synthesis of new flavonols as dual ɑ-amylase and ɑ-glucosidase inhibitors: Structure-activity relationship, drug-likeness, in vitro and in silico studies

(2020) Jamshaid Ashraf et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis of 4-alkylaminoimidazo[1,2-a]pyridines linked to carbamate moiety as potent α-glucosidase inhibitors

(2020) Mina Saeedi et al.   MOLECULAR DIVERSITY

Synthesis of novel Indole, 1,2,4-Triazole derivatives as potential glucosidase inhibitors

(2020) Ramesh S Gani et al.   JOURNAL OF KING SAUD UNIVERSITY SCIENCE

Celebrex derivatives: Synthesis, α-glucosidase inhibition, crystal structures and molecular docking studies

(2020) Nabeela Kausar et al.   BIOORGANIC CHEMISTRY

Design and synthesis of novel pyrazole-phenyl semicarbazone derivatives as potential α-glucosidase inhibitor: Kinetics and molecular dynamics simulation study

(2020) Fateme Azimi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Synthesis and biological evaluation of a new series of benzofuran‐1,3,4‐oxadiazole containing 1,2,3‐triazole‐acetamides as potential α‐glucosidase inhibitors

(2020) Fahimeh Abedinifar et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Oleanolic acid indole derivatives as novel α-glucosidase inhibitors: Synthesis, biological evaluation, and mechanistic analysis

(2020) Panpan Wu et al.   BIOORGANIC CHEMISTRY

A new biological prospective for the 2-phenylbenzofurans as inhibitors of α-glucosidase and of the islet amyloid polypeptide formation

(2020) Giovanna Lucia Delogu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Design and synthesis of new imidazo[1,2-b]pyrazole derivatives, in vitro α-glucosidase inhibition, kinetic and docking studies

(2019) Fariba Peytam et al.   MOLECULAR DIVERSITY

Design and synthesis of novel xanthone-triazole derivatives as potential antidiabetic agents: α-Glucosidase inhibition and glucose uptake promotion

(2019) Gao-Jie Ye et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of novel chromonyl enaminones as α-glucosidase inhibitors

(2019) Aarón Mendieta-Moctezuma et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis, In vitro α-Glucosidase Inhibitory Potential and Molecular Docking Studies of 2-Amino-1,3,4-Oxadiazole Derivatives

(2019) Hayat Ullah et al.   Medicinal Chemistry

Synthesis of novel tris-chalcones and determination of their inhibition profiles against some metabolic enzymes

(2019) Serdar Burmaoglu et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

A novel five‐step synthetic route to 1,3,4‐oxadiazole derivatives with potent α‐glucosidase inhibitory potential and their in silico studies

(2019) Muhammad Iftikhar et al.   ARCHIV DER PHARMAZIE

Synthetic heterocyclic candidates as promising α-glucosidase inhibitors: An overview

(2019) Manoj Dhameja et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Triazoloquinazolines as a new class of potent α-glucosidase inhibitors: in vitro evaluation and docking study

(2019) Hatem A. Abuelizz et al.   PLoS One

Biscoumarin-1,2,3-triazole hybrids as novel anti-diabetic agents: Design, synthesis, in vitro α-glucosidase inhibition, kinetic, and docking studies

(2019) Mohammad Sadegh Asgari et al.   BIOORGANIC CHEMISTRY

Synthesis, in vitro alpha-glucosidase inhibitory potential of benzimidazole bearing bis-Schiff bases and their molecular docking study

(2019) Fazal Rahim et al.   BIOORGANIC CHEMISTRY

Synthesis and Inhibitory Effect of Some Indole‐Pyrimidine Based Hybrid Heterocycles on α‐Glucosidase and α‐Amylase as Potential Hypoglycemic Agents

(2019) Farid A. Badria et al.   ChemistryOpen

Synthesis, Structural Studies, and α-Glucosidase Inhibitory, Antidiabetic, and Antioxidant Activities of 2,3-Dihydroquinazolin-4(1H)-ones Derived from Pyrazol-4-carbaldehyde and Anilines

(2019) Alireza Barmak et al.   ACS Omega

Design, synthesis, in vitro, and in silico studies of novel diarylimidazole-1,2,3-triazole hybrids as potent α-glucosidase inhibitors

(2019) Mina Saeedi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and biological evaluation of coumarin derivatives as α-glucosidase inhibitors

(2019) Xue-Tao Xu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Thiazolidine‐4‐one clubbed pyrazoles hybrids: Potent α‐amylase and α‐glucosidase inhibitors with NLO properties

(2019) Parvin Kumar et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Study on the interaction of 1,5-diaryl pyrrole derivatives with α-glucosidase; synthesis, molecular docking, and kinetic study

(2019) Tadesse Bekele Tafesse et al.   Medicinal Chemistry

Novel oxazolxanthone derivatives as a new type of α-glucosidase inhibitor: synthesis, activities, inhibitory modes and synergetic effect

(2018) Sen-Miao Ding et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, in vitro α-glucosidase inhibitory activity and docking studies of novel chromone-isatin derivatives

(2018) Guangcheng Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, α- glucosidase inhibition and molecular docking study of coumarin based derivatives

(2018) Muhammad Taha et al.   BIOORGANIC CHEMISTRY

Evaluation of α -glucosidase inhibiting potentials with docking calculations of synthesized arylidene-pyrazolones

(2018) Faryal Chaudhry et al.   BIOORGANIC CHEMISTRY

Catalytic asymmetric synthesis of indole derivatives as novel α -glucosidase inhibitors in vitro

(2018) Mohammad Shahidul Islam et al.   BIOORGANIC CHEMISTRY

Biological evaluation of new imidazole derivatives tethered with indole moiety as potent α-glucosidase inhibitors

(2018) Sadia Naureen et al.   BIOORGANIC CHEMISTRY

Oxindole based oxadiazole hybrid analogs: Novel α -glucosidase inhibitors

(2018) Muhammad Taha et al.   BIOORGANIC CHEMISTRY

Design, synthesis and in vitro α-glucosidase inhibition of novel dihydropyrano[3,2-c]quinoline derivatives as potential anti-diabetic agents

(2018) Hamideh Nikookar et al.   BIOORGANIC CHEMISTRY

Synthesis of Bis -indolylmethane sulfonohydrazides derivatives as potent α -Glucosidase inhibitors

(2018) Mohammed Gollapalli et al.   BIOORGANIC CHEMISTRY

A simple and efficient synthesis of benzimidazoles containing piperazine or morpholine skeleton at C-6 position as glucosidase inhibitors with antioxidant activity

(2018) Musa Özil et al.   BIOORGANIC CHEMISTRY

A new entry into the portfolio of α -glucosidase inhibitors as potent therapeutics for type 2 diabetes: Design, bioevaluation and one-pot multi-component synthesis of diamine-bridged coumarinyl oxadiazole conjugates

(2018) Madiha Kazmi et al.   BIOORGANIC CHEMISTRY

Synthesis, and In Vitro and In Silico α -Glucosidase Inhibitory Studies of 5-Chloro-2-Aryl Benzo[ d ]thiazoles

(2018) Shazia Shah et al.   BIOORGANIC CHEMISTRY

Synthesis, in vitro α-glucosidase inhibitory potential and molecular docking study of thiadiazole analogs

(2018) Muhammad Tariq Javid et al.   BIOORGANIC CHEMISTRY

Synthesis, biological evaluation, and docking studies of novel 5,6-diaryl-1,2,4-triazine thiazole derivatives as a new class of α -glucosidase inhibitors

(2018) Guangcheng Wang et al.   BIOORGANIC CHEMISTRY

Synthesis and biological evaluation of novel N -aryl-ω -(benzoazol-2-yl)-sulfanylalkanamides as dual inhibitors of α-glucosidase and protein tyrosine phosphatase 1B

(2018) Mei-Yan Wang et al.   Chemical Biology & Drug Design

Synthesis, biological evaluation and molecular docking studies of novel benzimidazole derivatives

(2018) Gagandeep Singh et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Synthesis, molecular modeling and evaluation of α-glucosidase inhibition activity of 3,4-dihydroxy piperidines

(2018) Siva Prasad Kasturi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

3-Benzyl(phenethyl)-2-thioxobenzo[g]quinazolines as a new class of potent α-glucosidase inhibitors: synthesis and molecular docking study

(2018) Rashad Al-Salahi et al.   Future Medicinal Chemistry

Synthesis & α-glucosidase inhibitory & glucose consumption-promoting activities of flavonoid–coumarin hybrids

(2018) Hua Sun et al.   Future Medicinal Chemistry

Synthesis of New Thiazolidine-2,-4-dione-azole Derivatives and Evaluation of Their α-Amylase and α-Glucosidase Inhibitory Activity

(2018) N. Senthilkumar et al.   Iranian Journal of Science and Technology Transaction A-Science

Synthesis and enzyme inhibitory kinetics of some novel 3-(substituted benzoyl)-2-thioxoimidazolidin-4-one derivatives as α-glucosidase/α-amylase inhibitors

(2018) Rabia Qamar et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis, in vitro $$\alpha $$α-glucosidase inhibitory activity, and in silico study of (E)-thiosemicarbazones and (E)-2-(2-(arylmethylene)hydrazinyl)-4-arylthiazole derivatives

(2018) Muhammad Ali et al.   MOLECULAR DIVERSITY

Design, synthesis and in vitro study of densely functionalized oxindoles as potent α-glucosidase inhibitors

(2018) Tania Luthra et al.   BIOORGANIC & MEDICINAL CHEMISTRY

New indole based hybrid oxadiazole scaffolds with N-substituted acetamides: As potent anti-diabetic agents

(2018) Majid Nazir et al.   BIOORGANIC CHEMISTRY

Synthesis of 1H-1,2,3-triazole derivatives as new α-glucosidase inhibitors and their molecular docking studies

(2018) Satya Kumar Avula et al.   BIOORGANIC CHEMISTRY

Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis in the Last Decade

(2018) Masha G. Savelieff et al.   CHEMICAL REVIEWS

Pyrrole: An insight into recent pharmacological advances with structure activity relationship

(2018) Shujauddin Ahmad et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A comprehensive review on xanthone derivatives as α-glucosidase inhibitors

(2018) Clementina M.M. Santos et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

SYNTHESIS, ANTIMICROBIAL AND α-GLUCOSIDASE INHIBITORY POTENTIAL OF MANNICH BASES OF MERCAPTO OXADIAZOLES AND THEIR MOLECULAR DOCKING STUDIES

(2018) SAKINA AHMAD   FARMACIA

Antioxidant, α-glucosidase inhibitory and in vitro antitumor activities of coumarin-benzothiazole hybrids

(2018) Moustafa T. Gabr   HETEROCYCLIC COMMUNICATIONS

Divergent synthesis of new α-glucosidase inhibitors obtained through a vinyl Grignard-mediated carbocyclisation

(2018) Ida M. B. Knudsen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

New Biscoumarin Derivatives as Potent α-Glucosidase Inhibitors: Synthesis, Biological Evaluation, Kinetic Analysis, and Docking Study

(2018) Maryam Mohammadi-Khanaposhtani et al.   POLYCYCLIC AROMATIC COMPOUNDS

Design and synthesis of novel quinazolinone-1,2,3-triazole hybrids as new anti-diabetic agents: In vitro α-glucosidase inhibition, kinetic, and docking study

(2018) Mina Saeedi et al.   BIOORGANIC CHEMISTRY

Imidazole-pyrazole hybrids: Synthesis, characterization and in-vitro bioevaluation against α-glucosidase enzyme with molecular docking studies

(2018) Faryal Chaudhry et al.   BIOORGANIC CHEMISTRY

In-silico studies of some oxadiazoles derivatives as anti-diabetic compounds

(2018) Muhammad Tukur Ibrahim et al.   JOURNAL OF KING SAUD UNIVERSITY SCIENCE

Synthesis, in vitro evaluation and molecular docking studies of novel triazine-triazole derivatives as potential α-glucosidase inhibitors

(2017) Guangcheng Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Hydrazinyl arylthiazole based pyridine scaffolds: Synthesis, structural characterization, in vitro α -glucosidase inhibitory activity, and in silico studies

(2017) Farman Ali et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, molecular structure, spectral analysis, and biological activity of new malonamide derivatives as α-glucosidase inhibitors

(2017) Assem Barakat et al.   JOURNAL OF MOLECULAR STRUCTURE

New prospects for the development of selective inhibitors of α -glucosidase based on coumarin-iminothiazolidinone hybrids: Synthesis, in-vitro biological screening and molecular docking analysis

(2017) Aliya Ibrar et al.   Journal of the Taiwan Institute of Chemical Engineers

Novel indolyl linked para-substituted benzylidene-based phenyl containing thiazolidienediones and their analogs as α-glucosidase inhibitors: synthesis, in vitro, and molecular docking studies

(2017) Jeewanjot Kaur et al.   MEDICINAL CHEMISTRY RESEARCH

Novel substituted 3-phenyl 1-(4-(5-bromopyridin-3-yl)-6-phenylpyrimidin-2-yl)-thiourea compounds as key small organic molecules for the potential treatment of type II diabetes mellitus: in vitro studies against yeast α-glucosidase

(2017) Tanzeel Ur Rehman et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis of 2-phenyl-1H-imidazo[4,5-b]pyridine as type 2 diabetes inhibitors and molecular docking studies

(2017) Muhammad Taha et al.   MEDICINAL CHEMISTRY RESEARCH

Design, synthesis and molecular docking study of novel pyrrole-based α-amylase and α-glucosidase inhibitors

(2017) Nikhil C. Jadhav et al.   MEDICINAL CHEMISTRY RESEARCH

Molecular docking and glucosidase inhibition studies of novel N-arylthiazole-2-amines and Ethyl 2-[aryl(thiazol-2-yl)amino]acetates

(2017) Ayesha Babar et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis, Biological Evaluation and Molecular Docking Study of 2-Substituted-4,6-Diarylpyrimidines as α-Glucosidase Inhibitors

(2017) Zipeng Gong et al.   MOLECULES

Synthesis, Biological Evaluation, and Molecular Docking Studies of Novel Isatin-Thiazole Derivatives as α-Glucosidase Inhibitors

(2017) et al.   MOLECULES

Synthesis, In Vitro α-Glucosidase Inhibitory Activity and Molecular Docking Studies of Novel Benzothiazole-Triazole Derivatives

(2017) Zipeng Gong et al.   MOLECULES

Synthesis, α-glucosidase inhibition and molecular docking studies of novel thiazolidine-2,4-dione or rhodanine derivatives

(2017) Guang-cheng Wang et al.   MedChemComm

Synthesis of 3-acyloxyxanthone derivatives as α-glucosidase inhibitors: A further insight into the 3-substituents’ effect

(2016) Gai-Li Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, biological evaluation and molecular docking study of N -arylbenzo[ d ]oxazol-2-amines as potential α-glucosidase inhibitors

(2016) Guangcheng Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of novel coumarin thiazole derivatives as α-glucosidase inhibitors

(2016) Guangcheng Wang et al.   BIOORGANIC CHEMISTRY

Synthesis,in vitroevaluation and molecular docking studies of novel coumarin-isatin derivatives as α-glucosidase inhibitors

(2016) Guangcheng Wang et al.   Chemical Biology & Drug Design

Heterocyclic Compounds: Effective α-Amylase and α-Glucosidase Inhibitors

(2016) Mina Saeedi et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Syntheses of new 3-thiazolyl coumarin derivatives, in vitro α -glucosidase inhibitory activity, and molecular modeling studies

(2016) Uzma Salar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis,In vitroand Docking Studies of New Flavone Ethers asα-Glucosidase Inhibitors

(2015) Syahrul Imran et al.   Chemical Biology & Drug Design

Synthesis of diethyl 4-substituted-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates as a new series of inhibitors against yeast α-glucosidase

(2015) Huma Niaz et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Re-exploring promising α-glucosidase inhibitors for potential development into oral anti-diabetic drugs: Finding needle in the haystack

(2015) Usman Ghani   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY