Synthesis, crystal structure, DFT, α-glucosidase and α-amylase inhibition and molecular docking studies of (E)-N'-(4-chlorobenzylidene)-5-phenyl-1H-pyrazole-3-carbohydrazide

Solvent induced supramolecular polymorphism in Cu(II) coordination complex built from 1,2,4-triazolo[1,5-a]pyrimidine: Crystal structures and anti-oxidant activity

(2020) Karim Chkirate et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Synthesis, X-ray structure, vibrational spectroscopy, DFT, biological evaluation and molecular docking studies of (E)-N'-(4-(dimethylamino)benzylidene)-5-methyl-1H-pyrazole-3-carbohydrazide

(2020) Khalid Karrouchi et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, spectroscopic characterization, crystal structure, DFT, molecular docking and in vitro antibacterial potential of novel quinoline derivatives

(2020) Younos Bouzian et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, crystal structure, hirshfeld surface analysis, DFT calculations, anti-diabetic activity and molecular docking studies of (E)-N’-(5-bromo-2-hydroxybenzylidene) isonicotinohydrazide

(2020) Khalid Karrouchi et al.   JOURNAL OF MOLECULAR STRUCTURE

Discovery of novel pyrazole derivatives as potential anticancer agents in MCL

(2019) Fansheng Ran et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Triazoloquinazolines as a new class of potent α-glucosidase inhibitors: in vitro evaluation and docking study

(2019) Hatem A. Abuelizz et al.   PLoS One

Synthesis and biological evaluation of a series of 2-(((5-akly/aryl-1H-pyrazol-3-yl)methyl)thio)-5-alkyl-6-(cyclohexylmethyl)-pyrimidin-4(3H)-ones as potential HIV-1 inhibitors

(2019) Yumeng Wu et al.   Acta Pharmaceutica Sinica B

Synthesis and biological evaluation of thiazolidine-2,4-dione-pyrazole conjugates as antidiabetic, anti-inflammatory and antioxidant agents

(2019) Garima Bansal et al.   BIOORGANIC CHEMISTRY

Discovery of δ-sultone-fused pyrazoles for treating Alzheimer's disease: Design, synthesis, biological evaluation and SAR studies

(2019) Yingying Xu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Potential antidiabetic activity and molecular docking studies of novel synthesized 3.6-dimethyl-5-oxo-pyrido[3,4-f][1,2,4]triazepino[2,3-a]benzimidazole and 10-amino-2-methyl-4-oxo pyrimido[1,2-a]benzimidazole derivatives

(2018) Youness El Bakri et al.   JOURNAL OF MOLECULAR MODELING

Synthesis, characterization, free-radical scavenging capacity and antioxidant activity of novel series of hydrazone, 1,3,4-oxadiazole and 1,2,4-triazole derived from 3,5-dimethyl-1H-pyrazole

(2018) Khalid Karrouchi et al.   Letters in Drug Design & Discovery

Synthesis and Pharmacological Activities of Pyrazole Derivatives: A Review

(2018) Khalid Karrouchi et al.   MOLECULES

Synthesis, crystal structure, DFT studies and biological activity of (Z)-3-(3-bromophenyl)-1-(1,5-dimethyl-1H-pyrazol-3-yl)-3-hydroxyprop-2-en-1-one

(2018) Said Tighadouini et al.   Chemistry Central Journal

Synthesis, spectroscopic characterization, reactive properties by DFT calculations, molecular dynamics simulations and biological evaluation of Schiff bases tethered 1,2,4-triazole and pyrazole rings

(2018) Renjith Raveendran Pillai et al.   JOURNAL OF MOLECULAR STRUCTURE

Novel Co(II) and Cu(II) coordination complexes constructed from pyrazole-acetamide: Effect of hydrogen bonding on the self assembly process and antioxidant activity

(2018) Karim Chkirate et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Recent advances of pyrazole-containing derivatives as anti-tubercular agents

(2017) Zhi Xu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New Pyrazole-Hydrazone Derivatives: X-ray Analysis, Molecular Structure Investigation via Density Functional Theory (DFT) and Their High In-Situ Catecholase Activity

(2017) Khalid Karrouchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

α-Glucosidase and α-amylase inhibitors from seed oil: A review of liposoluble substance to treat diabetes

(2016) Hui Teng et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

The therapeutic voyage of pyrazole and its analogs: A review

(2016) Mohemmed Faraz Khan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of cyantraniliprole, a potent and selective anthranilic diamide ryanodine receptor activator with cross-spectrum insecticidal activity

(2013) Thomas P. Selby et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Molecular Basis for the Recognition of Long-chain Substrates by Plant α-Glucosidases

(2013) Takayoshi Tagami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Epidemiology of Diabetes and Diabetes-Related Complications

(2008) Anjali D Deshpande et al.   PHYSICAL THERAPY