Synthesis of new clioquinol derivatives as potent α-glucosidase inhibitors; molecular docking, kinetic and structure–activity relationship studies

Synthesis, Antidiabetic Evaluation and Bioisosteric Modification of Quinoline Incorporated 2-pyrazoline Derivatives

(2021) Abhishek Kumar et al.   Indian Journal of Pharmaceutical Education and Research

Studies of synthesis, crystal structure and antidiabetic activity of quinolinium 2-carboxylate 2-chloroacetic acid

(2021) R. Kavitha et al.   JOURNAL OF MOLECULAR STRUCTURE

Anti-inflammatory and anti-diabetic activity of 8-Hydroxyquinolinium 3,5-Dinitrobenzoate

(2021) Dhurairaj Satheesh et al.   Chemical Data Collections

Synthesis, spectroscopic characterization, crystal structure, DFT, molecular docking and in vitro antibacterial potential of novel quinoline derivatives

(2020) Younos Bouzian et al.   JOURNAL OF MOLECULAR STRUCTURE

Current Pharmaceutical Aspects of Synthetic Quinoline Derivatives

(2020) Rukhsana Tabassum et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Protection of Primary Dopaminergic Midbrain Neurons Through Impact of Small Molecules Using Virtual Screening of GPR139 Supported by Molecular Dynamic Simulation and Systems Biology

(2019) Aman Chandra Kaushik et al.   Interdisciplinary Sciences-Computational Life Sciences

Rhizoma coptidis as a Potential Treatment Agent for Type 2 Diabetes Mellitus and the Underlying Mechanisms: A Review

(2019) Qian Ran et al.   Frontiers in Pharmacology

Discovery of Novel DPP-IV Inhibitors as Potential Candidates for the Treatment of Type 2 Diabetes mellitus Predicted by 3D QSAR Pharmacophore Models, Molecular Docking and de novo Evolution

(2019) Musoev et al.   MOLECULES

Synthesis of benzotriazoles derivatives and their dual potential as α-amylase and α-glucosidase inhibitors in vitro: Structure-activity relationship, molecular docking, and kinetic studies

(2019) Shehryar Hameed et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and in vitro α-glucosidase inhibition of novel dihydropyrano[3,2-c]quinoline derivatives as potential anti-diabetic agents

(2018) Hamideh Nikookar et al.   BIOORGANIC CHEMISTRY

Synthesis, biological evaluation, and docking studies of novel 5,6-diaryl-1,2,4-triazine thiazole derivatives as a new class of α -glucosidase inhibitors

(2018) Guangcheng Wang et al.   BIOORGANIC CHEMISTRY

Synthesis, molecular modeling and evaluation of α-glucosidase inhibition activity of 3,4-dihydroxy piperidines

(2018) Siva Prasad Kasturi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pyrano[3,2-c]quinoline derivatives as new class of α-glucosidase inhibitors to treat type 2 diabetes: synthesis, in vitro biological evaluation and kinetic study

(2018) Zahra Heydari et al.   Medicinal Chemistry

Synthesis of benzothiazole derivatives as a potent α-glucosidase inhibitor

(2018) Mohammed Gollapalli et al.   BIOORGANIC CHEMISTRY

Synthesis and evaluation of 2,3-indolotriterpenoids as new α-glucosidase inhibitors

(2017) Elmira F. Khusnutdinova et al.   MEDICINAL CHEMISTRY RESEARCH

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

(2017) Yan Zheng et al.   Nature Reviews Endocrinology

Clinical Review of Antidiabetic Drugs: Implications for Type 2 Diabetes Mellitus Management

(2017) Arun Chaudhury et al.   Frontiers in Endocrinology

Synthesis and Evaluation of α-Glucosidase and Pancreatic Lipase Inhibition by Quinazolinone-Coumarin Hybrids

(2016) Emre Menteşe et al.   Chemistry of Heterocyclic Compounds

Synthesis and antimicrobial activity of novel quinoline derivatives bearing pyrazoline and pyridine analogues

(2016) Nisheeth C. Desai et al.   MEDICINAL CHEMISTRY RESEARCH

Convenient synthesis, antimicrobial evaluation and molecular modeling of some novel quinoline derivatives

(2016) Wafaa S. Hamama et al.   SYNTHETIC COMMUNICATIONS

Therapeutic potential of α-glucosidase inhibitors in type 2 diabetes mellitus: an evidence-based review

(2015) Shashank R Joshi et al.   EXPERT OPINION ON PHARMACOTHERAPY

Quinoline-2-carboxylic acid isolated from Ephedra pachyclada and its structural derivatives show inhibitory effects against α-glucosidase and α-amylase

(2014) Hwa-Won Lee et al.   Journal of the Korean Society for Applied Biological Chemistry

Mini-Special Issue paper Management of diabetic patients with hypoglycemic agents α-Glucosidase inhibitors and their use in clinical practice

(2012) Giuseppe Derosa et al.   Archives of Medical Science

Synthesis and biological evaluation of novel N-acyl substituted quinolin-2(1H)-one derivatives as potential antimicrobial agents

(2012) Hong-Bin Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Pharmacokinetics, tolerability, and preliminary efficacy of paquinimod (ABR-215757), a new quinoline-3-carboxamide derivative: Studies in lupus-prone mice and a multicenter, randomized, double-blind, placebo-controlled, repeat-dose, dose-ranging study in

(2011) Anders A. Bengtsson et al.   ARTHRITIS AND RHEUMATISM

Identifying and Characterizing Binding Sites and Assessing Druggability

(2009) Thomas A. Halgren   Journal of Chemical Information and Modeling