Towards multi-target antidiabetic agents: In vitro and in vivo evaluation of 3,5-disubstituted indolin-2-one derivatives as novel α-glucosidase inhibitors

Discovery of pyrazole derivatives as cellular active inhibitors of histone lysine specific demethylase 5B (KDM5B/JARID1B)

(2020) Bing Zhao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3β inhibitors

(2019) Natalia A. Lozinskaya et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Improving the Potency of N-Aryl-2,5-dimethylpyrroles against Multidrug-Resistant and Intracellular Mycobacteria

(2019) Meir Touitou et al.   ACS Medicinal Chemistry Letters

Pharmacotherapy of type 2 diabetes: An update

(2018) Jagriti Upadhyay et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Synthesis, in vitro and in vivo evaluation of 2-aryl-4H-chromene and 3-aryl-1H-benzo[f]chromene derivatives as novel α-glucosidase inhibitors

(2018) Alexander A. Spasov et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Screening of minor bioactive compounds from herbal medicines by in silico docking and the trace peak exposure methods

(2016) Bin Wu et al.   JOURNAL OF CHROMATOGRAPHY A

Dihydropyrrolopyrazol-6-one MCHR1 antagonists for the treatment of obesity: Insights on in vivo efficacy from a novel FLIPR assay setup

(2015) Pratik Devasthale et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Evaluation of 2-indolcarbohydrazones as potent α-glucosidase inhibitors, in silico studies and DFT based stereochemical predictions

(2015) Muhammad Taha et al.   BIOORGANIC CHEMISTRY

Triazinoindole analogs as potent inhibitors of α-glucosidase: Synthesis, biological evaluation and molecular docking studies

(2015) Fazal Rahim et al.   BIOORGANIC CHEMISTRY

Design, Synthesis, and Characterization of 3-(Benzylidene)indolin-2-one Derivatives as Ligands for α-Synuclein Fibrils

(2015) Wenhua Chu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of novel oxindole derivatives as potent α-glucosidase inhibitors

(2014) Momin Khan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and biological evaluation of novel oxindole-based RTK inhibitors as anti-cancer agents

(2014) Gaozhi Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Xanthones fromSwertia mussotiias Multitarget-Directed Antidiabetic Agents

(2014) Huan-Huan Zheng et al.   ChemMedChem

Epigenetic mechanisms in diabetic complications and metabolic memory

(2014) Marpadga A. Reddy et al.   DIABETOLOGIA

Development of Novel Alkene Oxindole Derivatives As Orally Efficacious AMP-Activated Protein Kinase Activators

(2013) Li-Fang Yu et al.   ACS Medicinal Chemistry Letters

Advances in the Treatment of Type 2 Diabetes Mellitus

(2010) Zafar H Israili   AMERICAN JOURNAL OF THERAPEUTICS

7-Aminopyrazolo[1,5-a]pyrimidines as Potent Multitargeted Receptor Tyrosine Kinase Inhibitors

(2008) Robin R. Frey et al.   JOURNAL OF MEDICINAL CHEMISTRY