One-pot multi-component synthesis of novel chromeno[4,3-b]pyrrol-3-yl derivatives as alpha-glucosidase inhibitors

Synthesis of imidazole-pyrazole conjugates bearing aryl spacer and exploring their enzyme inhibition potentials

(2021) Faryal Chaudhry et al.   BIOORGANIC CHEMISTRY

Effects of alpha-glucosidase-inhibiting drugs on acute postprandial glucose and insulin responses: a systematic review and meta-analysis

(2021) Marjan Alssema et al.   Nutrition & Diabetes

Quinazolinone-dihydropyrano[3,2-b]pyran hybrids as new α-glucosidase inhibitors: Design, synthesis, enzymatic inhibition, docking study and prediction of pharmacokinetic

(2021) Maedeh Sherafati et al.   BIOORGANIC CHEMISTRY

Synthesis, in vitro evaluation, and molecular docking studies of novel hydrazineylideneindolinone linked to phenoxymethyl-1,2,3-triazole derivatives as potential α-glucosidase inhibitors

(2021) Diba Shareghi-Boroujeni et al.   BIOORGANIC CHEMISTRY

Design and synthesis of novel quinazolinone-pyrazole derivatives as potential α-glucosidase inhibitors: Structure-activity relationship, molecular modeling and kinetic study

(2021) Fateme Azimi et al.   BIOORGANIC CHEMISTRY

An efficient domino strategy for synthesis of 3-substituted 4-oxo-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine derivatives in water

(2021) Xiaopeng Yang et al.   MOLECULAR DIVERSITY

Potential Effect of Hydroxychloroquine in Diabetes Mellitus: A Systematic Review on Preclinical and Clinical Trial Studies

(2020) Dawit Zewdu Wondafrash et al.   Journal of Diabetes Research

Design and synthesis of novel pyrazole-phenyl semicarbazone derivatives as potential α-glucosidase inhibitor: Kinetics and molecular dynamics simulation study

(2020) Fateme Azimi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

DBU-mediated annulation of 2-aryl-3-nitro-2H-chromenes with 1,3-cyclohexanediones for the synthesis of benzofuro[2,3-c]chromenone derivatives

(2019) Chenlu Dai et al.   MOLECULAR DIVERSITY

The molecular diversity scope of 4-hydroxycoumarin in the synthesis of heterocyclic compounds via multicomponent reactions

(2019) Ghodsi Mohammadi Ziarani et al.   MOLECULAR DIVERSITY

Synthesis and kinetics studies of N′ ‐(2‐(3,5‐disubstituted‐4 H ‐1,2,4‐triazol‐4‐yl)acetyl)‐6/7/8‐substituted‐2‐oxo‐2 H ‐chromen‐3‐carbohydrazide derivatives as potent antidiabetic agents

(2019) Emre Menteşe et al.   ARCHIV DER PHARMAZIE

Treatment strategies against diabetes: Success so far and challenges ahead

(2019) Rubiya Khursheed et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Highly efficient, catalyst-free, one-pot, pseudo five-component synthesis of novel pyrazoline-containing Schiff bases, metal complexes formation and computational studies via DFT method

(2018) Alireza Hasaninejad et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Design, synthesis and in vitro α-glucosidase inhibition of novel dihydropyrano[3,2-c]quinoline derivatives as potential anti-diabetic agents

(2018) Hamideh Nikookar et al.   BIOORGANIC CHEMISTRY

Design, synthesis, docking study, α-glucosidase inhibition, and cytotoxic activities of acridine linked to thioacetamides as novel agents in treatment of type 2 diabetes

(2018) Maryam Mohammadi-Khanaposhtani et al.   BIOORGANIC CHEMISTRY

Iodine-catalyzed tandem oxidative coupling reaction: A one-pot strategy for the synthesis of new coumarin-fused pyrroles

(2018) Hoda Yahyavi et al.   TETRAHEDRON LETTERS

Pyrrole alkaloids and ergosterols from Grifola frondosa exert anti-α-glucosidase and anti-proliferative activities

(2018) Shaodan Chen et al.   Journal of Functional Foods

Highly efficient, catalyst-free, one-pot, pseudo-seven-component synthesis of novel poly-substituted pyrazolyl-1,2-diazepine derivatives

(2018) Sanaz Mojikhalifeh et al.   Organic Chemistry Frontiers

A Sustainable Synthesis of Functionalized Pyrrole Fused Coumarins under Solvent-Free Conditions Using Magnetic Nanocatalyst and a New Route to Polyaromatic Indolocoumarins

(2018) Sayan Mukherjee et al.   ChemistrySelect

A comprehensive review on xanthone derivatives as α-glucosidase inhibitors

(2018) Clementina M.M. Santos et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

One-pot, four-component synthesis of spiroindoloquinazoline derivatives as phospholipase inhibitors

(2017) Maryam Beyrati et al.   TETRAHEDRON

Design, synthesis and biological evaluation of novel coumarin thiazole derivatives as α-glucosidase inhibitors

(2016) Guangcheng Wang et al.   BIOORGANIC CHEMISTRY

Syntheses of new 3-thiazolyl coumarin derivatives, in vitro α -glucosidase inhibitory activity, and molecular modeling studies

(2016) Uzma Salar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

N-(2-(Piperazin-1-yl)phenyl)arylamide Derivatives as β-Secretase (BACE1) Inhibitors: Simple Synthesis by Ugi Four-Component Reaction and Biological Evaluation

(2015) Najmeh Edraki et al.   ARCHIV DER PHARMAZIE

Natural Products for the Treatment of Type 2 Diabetes Mellitus

(2015) José Ríos et al.   PLANTA MEDICA

An efficient synthesis of novel spiro[benzo[c]pyrano[3,2-a]phenazines] via domino multi-component reactions using l-proline as a bifunctional organocatalyst

(2013) Alireza Hasaninejad et al.   TETRAHEDRON LETTERS

Natural Products as α-Amylase and α-Glucosidase Inhibitors and their Hypoglycaemic Potential in the Treatment of Diabetes: An Update

(2010) R. Tundis et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Highly efficient synthesis of triazolo[1,2-a]indazole-triones and novel spiro triazolo[1,2-a]indazole-tetraones under solvent-free conditions

(2010) Alireza Hasaninejad et al.   TETRAHEDRON

Design and Screening Strategies for α-Glucosidase Inhibitors Based on Enzymological Information

(2009) Wataru Hakamata et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY