A review on synthesis, mechanism of action, and structure-activity relationships of 1,2,3-triazole-based α-glucosidase inhibitors as promising anti-diabetic agents

α-Glucosidase and α-amylase inhibition, molecular modeling and pharmacokinetic studies of new quinazolinone-1,2,3-triazole-acetamide derivatives

(2021) Ali Yavari et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis, in-vitro evaluation, molecular docking, and kinetic studies of pyridazine-triazole hybrid system as novel α-glucosidase inhibitors

(2021) Setareh Moghimi et al.   BIOORGANIC CHEMISTRY

Synthesis, in vitro evaluation, and molecular docking studies of novel hydrazineylideneindolinone linked to phenoxymethyl-1,2,3-triazole derivatives as potential α-glucosidase inhibitors

(2021) Diba Shareghi-Boroujeni et al.   BIOORGANIC CHEMISTRY

New phthalimide-benzamide-1,2,3-triazole hybrids; design, synthesis, α-glucosidase inhibition assay, and docking study

(2020) Seyed Esmaeil Sadat-Ebrahimi et al.   MEDICINAL CHEMISTRY RESEARCH

Design and synthesis of 4,5-diphenyl-imidazol-1,2,3-triazole hybrids as new anti-diabetic agents: in vitro α-glucosidase inhibition, kinetic and docking studies

(2020) Mohammad Sadegh Asgari et al.   MOLECULAR DIVERSITY

Synthesis, characterization, molecular docking, and biological activities of coumarin–1,2,3‐triazole‐acetamide hybrid derivatives

(2020) Nima Sepehri et al.   ARCHIV DER PHARMAZIE

New acridine-9-carboxamide linked to 1,2,3-triazole-N-phenylacetamide derivatives as potent α-glucosidase inhibitors: design, synthesis, in vitro, and in silico biological evaluations

(2020) Nima Sepehri et al.   MEDICINAL CHEMISTRY RESEARCH

Design, synthesis, biological evaluation, and docking study of new acridine‐9‐carboxamide linked to 1,2,3‐triazole derivatives as antidiabetic agents targeting α‐glucosidase

(2020) Mohammad S. Asgari et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Synthesis, antioxidant activity, and α‐glucosidase enzyme inhibition of α‐aminophosphonate derivatives bearing piperazine‐1,2,3‐triazole moiety

(2020) Madhu Kumar Reddy Kandula et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids

(2019) Bo Zhang   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis of novel xanthone-triazole derivatives as potential antidiabetic agents: α-Glucosidase inhibition and glucose uptake promotion

(2019) Gao-Jie Ye et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cyclodextrin-triazole-titanium based nanocomposite: Preparation, characterization and adsorption behavior investigation

(2019) Zari Fallah et al.   PROCESS SAFETY AND ENVIRONMENTAL PROTECTION

A new series of Schiff base derivatives bearing 1,2,3‐triazole: Design, synthesis, molecular docking, and α‐glucosidase inhibition

(2019) Ensieh Nasli‐Esfahani et al.   ARCHIV DER PHARMAZIE

On resin click-chemistry-mediated synthesis of novel enkephalin analogues with potent anti-nociceptive activity

(2019) Azzurra Stefanucci et al.   Scientific Reports

1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: A recent overview

(2019) Khurshed Bozorov et al.   BIOORGANIC & MEDICINAL CHEMISTRY

New thiosemicarbazide-1,2,3-triazole hybrids as potent α-glucosidase inhibitors: Design, synthesis, and biological evaluation

(2019) Zohreh Bakherad et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis of novel (R)-4-fluorophenyl-1H-1,2,3-triazoles: A new class of α-glucosidase inhibitors

(2019) Satya Kumar Avula et al.   BIOORGANIC CHEMISTRY

Biscoumarin-1,2,3-triazole hybrids as novel anti-diabetic agents: Design, synthesis, in vitro α-glucosidase inhibition, kinetic, and docking studies

(2019) Mohammad Sadegh Asgari et al.   BIOORGANIC CHEMISTRY

Design, synthesis, in vitro, and in silico studies of novel diarylimidazole-1,2,3-triazole hybrids as potent α-glucosidase inhibitors

(2019) Mina Saeedi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and biological evaluation of new benzimidazole-1,2,3-triazole hybrids as potential α-glucosidase inhibitors

(2019) Nafise Asemanipoor et al.   BIOORGANIC CHEMISTRY

Removal of fluoride ion from aqueous solutions by titania-grafted β-cyclodextrin nanocomposite

(2019) Zari Fallah et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Synthesis and biological evaluation of some novel 1,2,3-triazole hybrids of myrrhanone B isolated from Commiphora mukul gum resin: Identification of potent antiproliferative leads active against prostate cancer cells (PC-3)

(2019) Chandrashekhar Madasu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, in vivo and in silico evaluation of phenacyl triazole hydrazones as new anticonvulsant agents

(2018) Leila Dehestani et al.   BIOORGANIC CHEMISTRY

New 6-amino-pyrido[2,3- d ]pyrimidine-2,4-diones as novel agents to treat type 2 diabetes: A simple and efficient synthesis, α -glucosidase inhibition, molecular modeling and kinetic study

(2018) Mehdi Adib et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Quinazoline and quinazolinone as important medicinal scaffolds: a comparative patent review (2011–2016)

(2018) Abdul Hameed et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Design, synthesis, and cytotoxicity of novel coumarin-1,2,3-triazole-1,2,4-oxadiazole hybrids as potent anti-breast cancer agents

(2018) Maryam Mohammadi-Khanaposhtani et al.   Letters in Drug Design & Discovery

Synthesis of 1H-1,2,3-triazole derivatives as new α-glucosidase inhibitors and their molecular docking studies

(2018) Satya Kumar Avula et al.   BIOORGANIC CHEMISTRY

A comprehensive review on xanthone derivatives as α-glucosidase inhibitors

(2018) Clementina M.M. Santos et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and in vitro α-glucosidase inhibition of novel coumarin-pyridines as potent antidiabetic agents

(2018) Mehdi Adib et al.   NEW JOURNAL OF CHEMISTRY

Design, synthesis and anti-Alzheimer’s activity of novel 1,2,3-triazole-chromenone carboxamide derivatives

(2018) Arezoo Rastegari et al.   BIOORGANIC CHEMISTRY

Design and synthesis of novel quinazolinone-1,2,3-triazole hybrids as new anti-diabetic agents: In vitro α-glucosidase inhibition, kinetic, and docking study

(2018) Mina Saeedi et al.   BIOORGANIC CHEMISTRY

Synthesis, in vitro evaluation and molecular docking studies of novel triazine-triazole derivatives as potential α-glucosidase inhibitors

(2017) Guangcheng Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Management of Type 2 Diabetes in 2017

(2017) Jane E. B. Reusch et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Quinoliniumolate and 2H-1,2,3-Triazole Derivatives from the Stems of Paramignya trimera and Their α-Glucosidase Inhibitory Activities: In Vitro and in Silico Studies

(2017) Nhan T. Nguyen et al.   JOURNAL OF NATURAL PRODUCTS

Synthesis, in vitro and computational studies of 1,4-disubstituted 1,2,3-triazoles as potential α-glucosidase inhibitors

(2016) Farukh Jabeen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological evaluation of novel 2,4,5-triarylimidazole–1,2,3-triazole derivatives via click chemistry as α-glucosidase inhibitors

(2016) Guangcheng Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cu-Catalyzed Click Reaction in Carbohydrate Chemistry

(2016) Vinod K. Tiwari et al.   CHEMICAL REVIEWS

Synthesis and antioxidant property of novel 1,2,3-triazole-linked starch derivatives via ‘click chemistry’

(2016) Wenqiang Tan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Synthesis, docking and ADMET studies of novel chalcone triazoles for anti-cancer and anti-diabetic activity

(2015) Yakaiah Chinthala et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, in vitro cytotoxic activity evaluation, and apoptosis-induction study of new 9(10H)-acridinone-1,2,3-triazoles

(2015) Maryam Mohammadi-Khanaposhtani et al.   MOLECULAR DIVERSITY

1,2,3-Triazole derivatives as antitubercular agents: synthesis, biological evaluation and molecular docking study

(2015) Mubarak H. Shaikh et al.   MedChemComm

Synthesis of novel 1,2,3-triazole substituted-N-alkyl/aryl nitrone derivatives, their anti-inflammatory and anticancer activity

(2014) P. Sambasiva Rao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

1-Phenyl-1H- and 2-phenyl-2H-1,2,3-triazol derivatives: Design, synthesis and inhibitory effect on alpha-glycosidases

(2014) Daniel Gonzaga et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel imino sugar α-glucosidase inhibitors as antiviral compounds

(2013) J.D. Howe et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, biological evaluation and molecular modeling studies of some novel thiazolidinediones with triazole ring

(2013) Yakaiah Chinthala et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Maltase-Glucoamylase Modulates Gluconeogenesis and Sucrase-Isomaltase Dominates Starch Digestion Glucogenesis

(2013) Maricela Diaz-Sotomayor et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Design, synthesis, and antiviral activity of new 1H-1,2,3-triazole nucleoside ribavirin analogs

(2013) Maria de Lourdes G. Ferreira et al.   MEDICINAL CHEMISTRY RESEARCH

Diabetes: a 21st century challenge

(2013) Paul Z Zimmet et al.   Lancet Diabetes & Endocrinology

Synthesis of 1,2,3-triazole glycoconjugates as inhibitors of α-glucosidases

(2012) David R. da Rocha et al.   CARBOHYDRATE RESEARCH

Direct Starch Digestion by Sucrase-Isomaltase and Maltase-Glucoamylase

(2012) Amy Hui-Mei Lin et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

The copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) “click” reaction and its applications. An overview

(2011) Liyuan Liang et al.   COORDINATION CHEMISTRY REVIEWS

Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain

(2011) Nicolas Ardes-Guisot et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Application of click chemistry towards an efficient synthesis of 1,2,3-1H-triazolyl glycohybrids as enzyme inhibitors

(2010) Namarata Anand et al.   CARBOHYDRATE RESEARCH

An evaluation of the potential side-effects of α-glucosidase inhibitors used for the management of diabetes mellitus

(2010) A. J. J. REUSER et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Synthesis, Biological Activity, and Molecular Modeling Studies of 1H-1,2,3-Triazole Derivatives of Carbohydrates as α-Glucosidases Inhibitors

(2010) Sabrina B. Ferreira et al.   JOURNAL OF MEDICINAL CHEMISTRY

Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance

(2009) Ryuzo Kawamori et al.   LANCET

Cu-Catalyzed Azide−Alkyne Cycloaddition

(2008) Morten Meldal et al.   CHEMICAL REVIEWS

Synthesis, HIV-RT inhibitory activity and SAR of 1-benzyl-1H-1,2,3-triazole derivatives of carbohydrates

(2008) Fernando de C. da Silva et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antibiotic activity of a small molecules library of 1,2,3-triazole derivatives

(2007) Marie Aufort et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS