New quinoxalin‐1,3,4‐oxadiazole derivatives: Synthesis, characterization, in vitro biological evaluations, and molecular modeling studies

Cholinesterases, α-glycosidase, and carbonic anhydrase inhibition properties of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives: Synthetic analogues for the treatment of Alzheimer's disease and diabetes mellitus

(2020) Parham Taslimi et al.   BIOORGANIC CHEMISTRY

Tail approach synthesis of novel benzenesulfonamides incorporating 1,3,4-oxadiazole hybrids as potent inhibitor of carbonic anhydrase I, II, IX, and XII isoenzymes

(2020) Vikas Sharma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel amine-functionalized benzimidazolium salts: Synthesis, characterization, bioactivity, and molecular docking studies

(2020) Murat Yiğit et al.   JOURNAL OF MOLECULAR STRUCTURE

Biogenic nano silver: Synthesis, characterization, antibacterial, antibiofilms, and enzymatic activity

(2020) Nesrin Korkmaz et al.   ADVANCED POWDER TECHNOLOGY

Synthesis, characterization, biological evaluation, and in silico studies of novel 1,3‐diaryltriazene‐substituted sulfathiazole derivatives

(2020) Mesut Işık et al.   ARCHIV DER PHARMAZIE

Synthesis, characterization, molecular docking, and biological activities of coumarin–1,2,3‐triazole‐acetamide hybrid derivatives

(2020) Nima Sepehri et al.   ARCHIV DER PHARMAZIE

Determination of the inhibition profiles of pyrazolyl–thiazole derivatives against aldose reductase and α‐glycosidase and molecular docking studies

(2020) Yeliz Demir et al.   ARCHIV DER PHARMAZIE

Synthesis and antioxidant activities of phenol derivatives from 1,6-bis(dimethoxyphenyl)hexane-1,6-dione

(2020) Tekin Artunc et al.   BIOORGANIC CHEMISTRY

Bioactivity and molecular docking studies of some nickel complexes: New analogues for the treatment of Alzheimer, glaucoma and epileptic diseases

(2020) Dursun Kısa et al.   BIOORGANIC CHEMISTRY

Novel propanolamine derivatives attached to 2-metoxifenol moiety: Synthesis, characterization, biological properties, and molecular docking studies

(2020) Hayriye Genc Bilgicli et al.   BIOORGANIC CHEMISTRY

Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs

(2020) Nebih Lolak et al.   BIOORGANIC CHEMISTRY

Novel functionally substituted esters based on sodium diethyldithiocarbamate derivatives: Synthesis, characterization, biological activity and molecular docking studies

(2020) Alverdi Karimov et al.   BIOORGANIC CHEMISTRY

Evaluation of in vitro inhibitory effects of some natural compounds on tyrosinase activity and molecular docking study: Antimelanogenesis potential

(2020) Parham Taslimi   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Synthesis of water soluble tetra-substituted phthalocyanines: Investigation of DNA cleavage, cytotoxic effects and metabolic enzymes inhibition

(2020) Armağan Günsel et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, characterization, and biological studies of chalcone derivatives containing Schiff bases: Synthetic derivatives for the treatment of epilepsy and Alzheimer's disease

(2020) Ümit M. Koçyiğit et al.   ARCHIV DER PHARMAZIE

Probing 2-acetylbenzofuran hydrazones and their metal complexes as α-glucosidase inhibitors

(2020) Samra Khan et al.   BIOORGANIC CHEMISTRY

Synthesis of nitrogen, phosphorus, selenium and sulfur-containing heterocyclic compounds – Determination of their carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibition properties

(2020) İlhami Gülçin et al.   BIOORGANIC CHEMISTRY

Design and synthesis of novel pyrazole-phenyl semicarbazone derivatives as potential α-glucosidase inhibitor: Kinetics and molecular dynamics simulation study

(2020) Fateme Azimi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Synthesis, crystal structure, and biological evaluation of optically active 2-amino-4-aryl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H -chromen-3-carbonitriles: Antiepileptic, antidiabetic, and anticholinergics potentials

(2019) Abel Maharramov et al.   ARCHIV DER PHARMAZIE

Aminopyrazole-substituted metallophthalocyanines: Preparation, aggregation behavior, and investigation of metabolic enzymes inhibition properties

(2019) Emre Güzel et al.   ARCHIV DER PHARMAZIE

Phytochemical content, antioxidant activity, and enzyme inhibition effect of Salvia eriophora Boiss. & Kotschy against acetylcholinesterase, α-amylase, butyrylcholinesterase, and α-glycosidase enzymes

(2019) Ercan Bursal et al.   JOURNAL OF FOOD BIOCHEMISTRY

The antidiabetic and anticholinergic effects of chrysin on cyclophosphamide-induced multiple organ toxicity in rats: Pharmacological evaluation of some metabolic enzyme activities

(2019) Parham Taslimi et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Synthesis, characterization, molecular docking and biological activities of novel pyrazoline derivatives

(2019) Fikret Turkan et al.   ARCHIV DER PHARMAZIE

Synthesis, biological evaluation and molecular docking of novel pyrazole derivatives as potent carbonic anhydrase and acetylcholinesterase inhibitors

(2019) Fikret Turkan et al.   BIOORGANIC CHEMISTRY

Investigation of inhibitory properties of some hydrazone compounds on hCA I, hCA II and AChE enzymes

(2019) Kaan Kucukoglu et al.   BIOORGANIC CHEMISTRY

Sage (Salvia pilifera): determination of its polyphenol contents, anticholinergic, antidiabetic and antioxidant activities

(2019) İlhami Gülçin et al.   Journal of Food Measurement and Characterization

Novel eugenol bearing oxypropanolamines: Synthesis, characterization, antibacterial, antidiabetic, and anticholinergic potentials

(2019) Hayriye Genç Bilgiçli et al.   BIOORGANIC CHEMISTRY

Novel Molecular Hybrids of N-Benzylpiperidine and 1,3,4-Oxadiazole as Multitargeted Therapeutics to Treat Alzheimer’s Disease

(2019) Piyoosh Sharma et al.   ACS Chemical Neuroscience

A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer’s Disease

(2019) Gustavo Provensi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pyrazole[3,4-d]pyridazine derivatives: Molecular docking and explore of acetylcholinesterase and carbonic anhydrase enzymes inhibitors as anticholinergics potentials

(2019) Parham Taslimi et al.   BIOORGANIC CHEMISTRY

Novel 2-aminopyridine liganded Pd(II) N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure and bioactivity properties

(2019) Fatoş Erdemir et al.   BIOORGANIC CHEMISTRY

Design, synthesis, and biological evaluation of ferulic acid based 1,3,4-oxadiazole hybrids as multifunctional therapeutics for the treatment of Alzheimer’s disease

(2019) Avanish Tripathi et al.   BIOORGANIC CHEMISTRY

New 6-amino-pyrido[2,3- d ]pyrimidine-2,4-diones as novel agents to treat type 2 diabetes: A simple and efficient synthesis, α -glucosidase inhibition, molecular modeling and kinetic study

(2018) Mehdi Adib et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antioxidant and anticholinergic properties of olivetol

(2018) Parham Taslimi et al.   JOURNAL OF FOOD BIOCHEMISTRY

Synthesis, characterization and crystal structure of 2-(4-hydroxyphenyl)ethyl and 2-(4-nitrophenyl)ethyl Substituted Benzimidazole Bromide Salts: Their inhibitory properties against carbonic anhydrase and acetylcholinesterase

(2018) Ayten Behçet et al.   JOURNAL OF MOLECULAR STRUCTURE

The effects of some antibiotics from cephalosporin groups on the acetylcholinesterase and butyrylcholinesterase enzymes activities in different tissues of rats

(2018) Fikret Türkan et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Diarylmethanon, bromophenol and diarylmethane compounds: Discovery of potent aldose reductase, α-amylase and α-glycosidase inhibitors as new therapeutic approach in diabetes and functional hyperglycemia

(2018) Parham Taslimi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Antidiabetic and antiparasitic potentials: Inhibition effects of some natural antioxidant compounds on α-glycosidase, α-amylase and human glutathione S-transferase enzymes

(2018) İlhami Gulçin et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

In vitro cytotoxic and in vivo antitumoral activities of some aminomethyl derivatives of 2,4-dihydro-3H-1,2,4-triazole-3-thiones-Evaluation of their acetylcholinesterase and carbonic anhydrase enzymes inhibition profiles

(2018) İrfan Timur et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Synthesis and characterization of novel substituted thiophene derivatives and discovery of their carbonic anhydrase and acetylcholinesterase inhibition effects

(2018) Adnan Cetin et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

The effects of hesperidin on sodium arsenite-induced different organ toxicity in rats on metabolic enzymes as antidiabetic and anticholinergics potentials: A biochemical approach

(2018) Cuneyt Caglayan et al.   JOURNAL OF FOOD BIOCHEMISTRY

Comprehensive review of mechanisms of pathogenesis involved in Alzheimer’s disease and potential therapeutic strategies

(2018) Piyoosh Sharma et al.   PROGRESS IN NEUROBIOLOGY

Imidazolinium chloride salts bearing wingtip groups: Synthesis, molecular docking and metabolic enzymes inhibition

(2018) Beyhan Yiğit et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, characterization, crystal structure of novel bis-thiomethylcyclohexanone derivatives and their inhibitory properties against some metabolic enzymes

(2018) Abdullah Biçer et al.   BIOORGANIC CHEMISTRY

The first synthesis, carbonic anhydrase inhibition and anticholinergic activities of some bromophenol derivatives with S including natural products

(2018) Cetin Bayrak et al.   BIOORGANIC CHEMISTRY

Synthesis, characterization and biological evaluation of novel 2,5 substituted-1,3,4 oxadiazole derivatives

(2017) Selvaraj Kavitha et al.   SAUDI PHARMACEUTICAL JOURNAL

Benzylpiperidine-Linked Diarylthiazoles as Potential Anti-Alzheimer’s Agents: Synthesis and Biological Evaluation

(2016) Mahesh Shidore et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure-Based Search for New Inhibitors of Cholinesterases

(2013) Marek Bajda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Rapid screening and identification ofα-glucosidase inhibitors from mulberry leaves using enzyme-immobilized magnetic beads coupled with HPLC/MS and NMR

(2012) Yi Tao et al.   BIOMEDICAL CHROMATOGRAPHY

1,3,4-Oxadiazole: A Biologically Active Scaffold

(2012) H. Khalilullah et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Practical Considerations for Building GROMOS-Compatible Small-Molecule Topologies

(2010) Justin A. Lemkul et al.   Journal of Chemical Information and Modeling