Therapeutic Approaches for Treating Pulmonary Arterial Hypertension by Correcting Imbalanced TGF-β Superfamily Signaling
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Title
Therapeutic Approaches for Treating Pulmonary Arterial Hypertension by Correcting Imbalanced TGF-β Superfamily Signaling
Authors
Keywords
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Journal
Frontiers in Medicine
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2022-01-24
DOI
10.3389/fmed.2021.814222
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Note: Only part of the references are listed.- Discovery of a new class of integrin antibodies for fibrosis
- (2021) Ji Zhang et al. Scientific Reports
- Altered TGFβ/SMAD Signaling in Human and Rat Models of Pulmonary Hypertension: An Old Target Needs Attention
- (2021) Takayuki Jujo Sanada et al. Cells
- Central Role of Dendritic Cells in Pulmonary Arterial Hypertension in Human and Mice
- (2021) Denise van Uden et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Relationship between serum myostatin levels and carotid-femoral pulse wave velocity in healthy young male adolescents. The Maciste Study
- (2021) Giacomo Pucci et al. JOURNAL OF APPLIED PHYSIOLOGY
- Pulmonary Arterial Hypertension: Diagnosis, Treatment, and Novel Advances
- (2021) Bradley A Maron et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Improving Right Ventricular Function by Increasing BMP Signaling with FK506
- (2021) Mario Boehm et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Epithelial plasticity, epithelial-mesenchymal transition, and the TGF-β family
- (2021) Yoko Katsuno et al. DEVELOPMENTAL CELL
- Nonclinical Development of SRK-181: An Anti-Latent TGFβ1 Monoclonal Antibody for the Treatment of Locally Advanced or Metastatic Solid Tumors
- (2021) Brian T. Welsh et al. INTERNATIONAL JOURNAL OF TOXICOLOGY
- TGF ‐β as a driver of fibrosis: physiological roles and therapeutic opportunities
- (2021) Erine H Budi et al. JOURNAL OF PATHOLOGY
- Sotatercept for the Treatment of Pulmonary Arterial Hypertension
- (2021) Marc Humbert et al. NEW ENGLAND JOURNAL OF MEDICINE
- iPSC–endothelial cell phenotypic drug screening and in silico analyses identify tyrphostin-AG1296 for pulmonary arterial hypertension
- (2021) Mingxia Gu et al. Science Translational Medicine
- Targeting the TGF-β signaling pathway for resolution of pulmonary arterial hypertension
- (2021) Nahid Sharmin et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension
- (2021) Gusty R. T. Ryanto et al. Nature Communications
- Different cardiovascular and pulmonary phenotypes for single- and double-knock-out mice deficient in BMP9 and BMP10
- (2021) Claire Bouvard et al. CARDIOVASCULAR RESEARCH
- Regulation of The Methylation and Expression Levels of the BMPR2 Gene by SIN3a As A Novel Therapeutic Mechanism in Pulmonary Arterial Hypertension
- (2021) Malik Bisserier et al. CIRCULATION
- Principles of the activin receptor signaling pathway and its inhibition
- (2021) Andreas Lodberg CYTOKINE & GROWTH FACTOR REVIEWS
- BMP9 and BMP10 : Two close vascular quiescence partners that stand out
- (2021) Agnès Desroches‐Castan et al. DEVELOPMENTAL DYNAMICS
- Emerging therapeutic opportunities for integrin inhibitors
- (2021) R. J. Slack et al. NATURE REVIEWS DRUG DISCOVERY
- The therapeutic potential of apelin in kidney disease
- (2021) Fiona A. Chapman et al. Nature Reviews Nephrology
- Activation of Smad2/3 signaling by low fluid shear stress mediates artery inward remodeling
- (2021) Hanqiang Deng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anti-latent TGFβ binding protein 4 antibody improves muscle function and reduces muscle fibrosis in muscular dystrophy
- (2021) Alexis R. Demonbreun et al. Science Translational Medicine
- TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis
- (2021) Tianhe Sun et al. Science Translational Medicine
- A myostatin-CCL20–CCR6 axis regulates Th17 cell recruitment to inflamed joints in experimental arthritis
- (2021) Michelle Fennen et al. Scientific Reports
- LTBP4 in Health and Disease
- (2021) Chi-Ting Su et al. Genes
- Mechanical forces regulate endothelial-to-mesenchymal transition and atherosclerosis via an Alk5-Shc mechanotransduction pathway
- (2021) Vedanta Mehta et al. Science Advances
- Myostatin/Activin-A Signaling in the Vessel Wall and Vascular Calcification
- (2021) Pasquale Esposito et al. Cells
- 4PBA Restores Signalling of a Cysteine-substituted Mutant BMPR2 Receptor Found in Patients with PAH
- (2020) Benjamin J Dunmore et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension
- (2020) Lai-Ming Yung et al. Science Translational Medicine
- Targeting Transforming Growth Factor Beta Receptors in Pulmonary Hypertension
- (2020) Christophe Guignabert et al. EUROPEAN RESPIRATORY JOURNAL
- Vital Roles of Gremlin‐1 in Pulmonary Arterial Hypertension Induced by Systemic‐to‐Pulmonary Shunts
- (2020) Liukun Meng et al. Journal of the American Heart Association
- Dysregulation of BMP9/BMPR2/SMAD Signaling Pathway Contributes to the Bleomycin‐induced Pulmonary Fibrosis and Pulmonary Hypertension in a Rat Model
- (2020) Qian Jiang et al. BRITISH JOURNAL OF PHARMACOLOGY
- TGFβ-Directed Therapeutics: 2020
- (2020) Beverly A. Teicher PHARMACOLOGY & THERAPEUTICS
- Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis
- (2020) Alison E. John et al. Nature Communications
- It Takes Two to Tango: Endothelial TGFβ/BMP Signaling Crosstalk with Mechanobiology
- (2020) Christian Hiepen et al. Cells
- Circulating BMP9 Protects the Pulmonary Endothelium During Inflammation-induced Lung Injury in Mice
- (2020) Wei Li et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Approaches to treat pulmonary arterial hypertension by targeting BMPR2: from cell membrane to nucleus
- (2020) Benjamin J Dunmore et al. CARDIOVASCULAR RESEARCH
- PPARγ-p53-Mediated Vasculoregenerative Program to Reverse Pulmonary Hypertension
- (2020) Jan K Hennigs et al. CIRCULATION RESEARCH
- Novel Advances in Modifying BMPR2 Signaling in PAH
- (2020) Svenja Dannewitz Prosseda et al. Genes
- Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension
- (2019) Ly Tu et al. CIRCULATION RESEARCH
- Activin type II receptor signaling in cardiac aging and heart failure
- (2019) Jason D. Roh et al. Science Translational Medicine
- Specificity, versatility, and control of TGF-β family signaling
- (2019) Rik Derynck et al. Science Signaling
- Berberine attenuates hypoxia-induced pulmonary arterial hypertension via bone morphogenetic protein and transforming growth factor-β signaling
- (2019) Mingxing Chen et al. JOURNAL OF CELLULAR PHYSIOLOGY
- A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension
- (2019) Peiran Yang et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cellular inflammation in pulmonary hypertension: Detailed analysis of lung and right ventricular tissue, circulating immune cells and effects of a dual endothelin receptor antagonist
- (2019) Ilonka Rohm et al. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
- BMPR2‐expressing bone marrow‐derived endothelial‐like progenitor cells alleviate pulmonary arterial hypertension in vivo
- (2019) Rebecca L. Harper et al. RESPIROLOGY
- 6-mercaptopurine, an agonist of Nur77, reduces progression of pulmonary hypertension by enhancing BMP signalling
- (2019) Kondababu Kurakula et al. EUROPEAN RESPIRATORY JOURNAL
- Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity
- (2019) Erich J. Goebel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis
- (2019) Joseph Yusup Shin et al. Science Translational Medicine
- Phenotypically-Silent Bone Morphogenetic Protein Receptor 2 ( Bmpr2 ) Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing The Risk for Neointimal Transformation
- (2019) Wen Tian et al. CIRCULATION
- Molecular genetic framework underlying pulmonary arterial hypertension
- (2019) Laura Southgate et al. Nature Reviews Cardiology
- Non-canonical (non-SMAD2/3) TGF-β signaling in fibrosis: Mechanisms and targets
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- BMPR2 acts as a gatekeeper to protect endothelial cells from increased TGFβ responses and altered cell mechanics
- (2019) Christian Hiepen et al. PLOS BIOLOGY
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- (2018) Xiufeng Yu et al. HYPERTENSION
- Thrombospondin-1 regulation of latent TGF-β activation: A therapeutic target for fibrotic disease
- (2018) Joanne E. Murphy-Ullrich et al. MATRIX BIOLOGY
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- (2018) Glenn Marsboom et al. MOLECULAR BIOLOGY OF THE CELL
- Identification of rare sequence variation underlying heritable pulmonary arterial hypertension
- (2018) Stefan Gräf et al. Nature Communications
- Sotatercept with long-term extension for the treatment of anaemia in patients with lower-risk myelodysplastic syndromes: a phase 2, dose-ranging trial
- (2018) Rami Komrokji et al. Lancet Haematology
- TGF-β Signaling-Related Genes and Thoracic Aortic Aneurysms and Dissections
- (2018) Norifumi Takeda et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Consequences of BMPR2 Deficiency in the Pulmonary Vasculature and Beyond: Contributions to Pulmonary Arterial Hypertension
- (2018) Adam Andruska et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TGFβ and BMPRII signalling pathways in the pathogenesis of pulmonary arterial hypertension
- (2018) Birger Tielemans et al. DRUG DISCOVERY TODAY
- Germline BMP9 mutation causes idiopathic pulmonary arterial hypertension
- (2018) Xiao-Jian Wang et al. EUROPEAN RESPIRATORY JOURNAL
- Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives
- (2018) Marc Humbert et al. EUROPEAN RESPIRATORY JOURNAL
- Genetics and genomics of pulmonary arterial hypertension
- (2018) Nicholas W. Morrell et al. EUROPEAN RESPIRATORY JOURNAL
- Sotatercept, a novel transforming growth factor beta ligand trap, improves anemia in beta-thalassemia: a phase 2, open-label, dose-finding study
- (2018) Maria Domenica Cappellini et al. HAEMATOLOGICA
- Assessment of reversibility in pulmonary arterial hypertension and congenital heart disease
- (2018) Diederik E van der Feen et al. HEART
- Randomised placebo-controlled safety and tolerability trial of FK506 (tacrolimus) for pulmonary arterial hypertension
- (2017) Edda Spiekerkoetter et al. EUROPEAN RESPIRATORY JOURNAL
- A disease-associated frameshift mutation in caveolin-1 disrupts caveolae formation and function through introduction of a de novo ER retention signal
- (2017) Courtney A. Copeland et al. MOLECULAR BIOLOGY OF THE CELL
- Bone Morphogenetic Proteins in Vascular Homeostasis and Disease
- (2017) Marie-José Goumans et al. Cold Spring Harbor Perspectives in Biology
- TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension
- (2017) Rahul Kumar et al. Nature Communications
- Myostatin mediates abdominal aortic atherosclerosis progression by inducing vascular smooth muscle cell dysfunction and monocyte recruitment
- (2017) D. Verzola et al. Scientific Reports
- A Selective Transforming Growth Factor-β Ligand Trap Attenuates Pulmonary Hypertension
- (2016) Lai-Ming Yung et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Transforming Growth Factor-β: Master Regulator of the Respiratory System in Health and Disease
- (2016) Yael Aschner et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Transforming growth factor-beta1 upregulation triggers pulmonary artery smooth muscle cell proliferation and apoptosis imbalance in rats with hypoxic pulmonary hypertension via the PTEN/AKT pathways
- (2016) Yun Liu et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Elevated levels of plasma transforming growth factor-β1 in idiopathic and heritable pulmonary arterial hypertension
- (2016) Yi Yan et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Transforming Growth Factor-β Family Ligands Can Function as Antagonists by Competing for Type II Receptor Binding
- (2016) Senem Aykul et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Blood flow boosts BMP signaling to keep vessels in shape
- (2016) Claudio A. Franco et al. JOURNAL OF CELL BIOLOGY
- Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia
- (2016) Nicolas Baeyens et al. JOURNAL OF CELL BIOLOGY
- Partial inhibition of activin receptor-like kinase 4 attenuates pressure overload-induced cardiac fibrosis and improves cardiac function
- (2016) Chang-Yi Li et al. JOURNAL OF HYPERTENSION
- Bosentan reverses the hypoxia-induced downregulation of the bone morphogenetic protein signaling in pulmonary artery smooth muscle cells
- (2016) Hidekazu Maruyama et al. LIFE SCIENCES
- TGF-β1 inhibits the apoptosis of pulmonary arterial smooth muscle cells and contributes to pulmonary vascular medial thickening via the PI3K/Akt pathway
- (2016) LIMIN LI et al. Molecular Medicine Reports
- TGF-β: the master regulator of fibrosis
- (2016) Xiao-ming Meng et al. Nature Reviews Nephrology
- BMPR2 gene therapy for PAH acts via Smad and non-Smad signalling
- (2016) Rebecca L. Harper et al. RESPIROLOGY
- Structural Biology and Evolution of the TGF-β Family
- (2016) Andrew P. Hinck et al. Cold Spring Harbor Perspectives in Biology
- Non-Smad Signaling Pathways of the TGF-β Family
- (2016) Ying E. Zhang Cold Spring Harbor Perspectives in Biology
- Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins
- (2016) Ian B. Robertson et al. Cold Spring Harbor Perspectives in Biology
- Novel homozygous BMP9 nonsense mutation causes pulmonary arterial hypertension: a case report
- (2016) Guoliang Wang et al. BMC Pulmonary Medicine
- Low-Dose FK506 (Tacrolimus) in End-Stage Pulmonary Arterial Hypertension
- (2015) Edda Spiekerkoetter et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Long-term safety and efficacy of imatinib in pulmonary arterial hypertension
- (2015) Adaani E. Frost et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- Intrinsic BMP Antagonist Gremlin-1 as a Novel Circulating Marker in Pulmonary Arterial Hypertension
- (2015) Jasmin Wellbrock et al. LUNG
- Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension
- (2015) Lu Long et al. NATURE MEDICINE
- Sotatercept (ACE-011) for the treatment of chemotherapy-induced anemia in patients with metastatic breast cancer or advanced or metastatic solid tumors treated with platinum-based chemotherapeutic regimens: results from two phase 2 studies
- (2015) Haralambos Raftopoulos et al. SUPPORTIVE CARE IN CANCER
- Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system
- (2015) Peiran Yang et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Sotatercept in patients with osteolytic lesions of multiple myeloma
- (2014) Kudrat M. Abdulkadyrov et al. BRITISH JOURNAL OF HAEMATOLOGY
- Inflammation and Immunity in the Pathogenesis of Pulmonary Arterial Hypertension
- (2014) Marlene Rabinovitch et al. CIRCULATION RESEARCH
- Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension
- (2014) Hirofumi Sawada et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Treatment with Anti–Gremlin 1 Antibody Ameliorates Chronic Hypoxia/SU5416–Induced Pulmonary Arterial Hypertension in Mice
- (2013) Loredana Ciuclan et al. AMERICAN JOURNAL OF PATHOLOGY
- Pathogenesis of pulmonary hypertension: a case for caveolin-1 and cell membrane integrity
- (2013) Rajamma Mathew AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Transforming Growth Factor-β1Represses Bone Morphogenetic Protein–Mediated Smad Signaling in Pulmonary Artery Smooth Muscle Cells via Smad3
- (2013) Paul D. Upton et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Circulating Bmp10 acts through endothelial Alk1 to mediate flow-dependent arterial quiescence
- (2013) D. W. Laux et al. DEVELOPMENT
- FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension
- (2013) Edda Spiekerkoetter et al. JOURNAL OF CLINICAL INVESTIGATION
- Multiple-dose, safety, pharmacokinetic, and pharmacodynamic study of sotatercept (ActRIIA-IgG1), a novel erythropoietic agent, in healthy postmenopausal women
- (2013) Matthew L. Sherman et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Genetics and Genomics of Pulmonary Arterial Hypertension
- (2013) Florent Soubrier et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Right Heart Adaptation to Pulmonary Arterial Hypertension
- (2013) Anton Vonk-Noordegraaf et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Inhibition of apelin expression by BMP signaling in endothelial cells
- (2012) Odette Poirier et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Immune and Inflammatory Cell Involvement in the Pathology of Idiopathic Pulmonary Arterial Hypertension
- (2012) Rajkumar Savai et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Longitudinal Analysis Casts Doubt on the Presence of Genetic Anticipation in Heritable Pulmonary Arterial Hypertension
- (2012) Emma K. Larkin et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Gremlin Plays a Key Role in the Pathogenesis of Pulmonary Hypertension
- (2012) Edwina Cahill et al. CIRCULATION
- Whole Exome Sequencing to Identify a Novel Gene (Caveolin-1) Associated With Human Pulmonary Arterial Hypertension
- (2012) Eric D. Austin et al. Circulation-Cardiovascular Genetics
- AntagomiR directed against miR-20a restores functional BMPR2 signalling and prevents vascular remodelling in hypoxia-induced pulmonary hypertension
- (2012) Matthias Brock et al. EUROPEAN HEART JOURNAL
- ALK2 and BMPR2 knockdown and endothelin-1 production by pulmonary microvascular endothelial cells
- (2012) Gregory P. Star et al. MICROVASCULAR RESEARCH
- GARP regulates the bioavailability and activation of TGFβ
- (2012) Rui Wang et al. MOLECULAR BIOLOGY OF THE CELL
- Transforming Growth Factor-β Inhibition and Endothelin Receptor Blockade in Rats with Monocrotaline-Induced Pulmonary Hypertension
- (2012) Aikaterini J. Megalou et al. Pulmonary Circulation
- Disruption of the Apelin-APJ System Worsens Hypoxia-Induced Pulmonary Hypertension
- (2011) Suparna M. Chandra et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Non-Smad signaling pathways
- (2011) Yabing Mu et al. CELL AND TISSUE RESEARCH
- The specificities of small molecule inhibitors of the TGFß and BMP pathways
- (2011) Janis Vogt et al. CELLULAR SIGNALLING
- Interaction between alk1 and blood flow in the development of arteriovenous malformations
- (2011) P. Corti et al. DEVELOPMENT
- Targeted gene delivery of BMPR2 attenuates pulmonary hypertension
- (2011) A. M. Reynolds et al. EUROPEAN RESPIRATORY JOURNAL
- Molecular genetic characterization of SMAD signaling molecules in pulmonary arterial hypertension
- (2011) Md. Talat Nasim et al. HUMAN MUTATION
- Disruption of PPARγ/β-catenin–mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival
- (2011) Tero-Pekka Alastalo et al. JOURNAL OF CLINICAL INVESTIGATION
- Induction of Heart Valve Lesions by Small-Molecule ALK5 Inhibitors
- (2011) Mark J. Anderton et al. TOXICOLOGIC PATHOLOGY
- Imatinib in Pulmonary Arterial Hypertension Patients with Inadequate Response to Established Therapy
- (2010) Hossein A. Ghofrani et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension
- (2009) Inês Falcão-Pires et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Role of Gremlin in the Lung
- (2009) Christine M. Costello et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Altered Bone Morphogenetic Protein and Transforming Growth Factor-β Signaling in Rat Models of Pulmonary Hypertension
- (2009) Lu Long et al. CIRCULATION
- Noncanonical transforming growth factor β signaling in scleroderma fibrosis
- (2009) Maria Trojanowska CURRENT OPINION IN RHEUMATOLOGY
- Growth factors and interleukin-6 across the lung circulation in pulmonary hypertension
- (2009) N. Selimovic et al. EUROPEAN RESPIRATORY JOURNAL
- A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension
- (2009) M Shintani et al. JOURNAL OF MEDICAL GENETICS
- Activin-Like Kinase 5 (ALK5) Mediates Abnormal Proliferation of Vascular Smooth Muscle Cells from Patients with Familial Pulmonary Arterial Hypertension and Is Involved in the Progression of Experimental Pulmonary Arterial Hypertension Induced by Monocrotaline
- (2008) Matthew Thomas et al. AMERICAN JOURNAL OF PATHOLOGY
- Role of the TGF-β/Alk5 Signaling Pathway in Monocrotaline-induced Pulmonary Hypertension
- (2008) Ari L. Zaiman et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Genetic Ablation of the Bmpr2 Gene in Pulmonary Endothelium Is Sufficient to Predispose to Pulmonary Arterial Hypertension
- (2008) Kwon-Ho Hong et al. CIRCULATION
- Mutations in Bone Morphogenetic Protein Type II Receptor Cause Dysregulation of Id Gene Expression in Pulmonary Artery Smooth Muscle Cells
- (2008) Jun Yang et al. CIRCULATION RESEARCH
- Interleukin-6 Overexpression Induces Pulmonary Hypertension
- (2008) M. Kathryn Steiner et al. CIRCULATION RESEARCH
- Synergistic heterozygosity for TGFβ1 SNPs and BMPR2 mutations modulates the age at diagnosis and penetrance of familial pulmonary arterial hypertension
- (2008) John A Phillips et al. GENETICS IN MEDICINE
- Single-Dose, Randomized, Double-Blind, Placebo-Controlled Study of ACE-011 (ActRIIA-IgG1) in Postmenopausal Women*
- (2008) Jon Ruckle et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Implications of Mutations of Activin Receptor-Like Kinase 1 Gene (ALK1) in Addition to Bone Morphogenetic Protein Receptor II Gene (BMPR2) in Children With Pulmonary Arterial Hypertension
- (2007) Maya Fujiwara et al. CIRCULATION JOURNAL
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