TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension
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Title
TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension
Authors
Keywords
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Journal
Nature Communications
Volume 8, Issue -, Pages 15494
Publisher
Springer Nature
Online
2017-05-30
DOI
10.1038/ncomms15494
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Note: Only part of the references are listed.- TSP1–CD47 signaling is upregulated in clinical pulmonary hypertension and contributes to pulmonary arterial vasculopathy and dysfunction
- (2016) Natasha M. Rogers et al. CARDIOVASCULAR RESEARCH
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- (2015) Mario E. Lacouture et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
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- (2015) David Labrousse-Arias et al. CARDIOVASCULAR RESEARCH
- Thrombospondin-1 (TSP1) Contributes to the Development of Vascular Inflammation by Regulating Monocytic Cell Motility in Mouse Models of Abdominal Aortic AneurysmNovelty and Significance
- (2015) Zhenjie Liu et al. CIRCULATION RESEARCH
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- (2015) Irina N. Shalova et al. IMMUNITY
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- (2015) L A Borthwick et al. Mucosal Immunology
- A Longitudinal Biomarker for the Extent of Skin Disease in Patients With Diffuse Cutaneous Systemic Sclerosis
- (2015) Lisa M. Rice et al. Arthritis & Rheumatology
- TGF beta and IL13 in schistosomiasis mansoni associated pulmonary arterial hypertension; a descriptive study with comparative groups
- (2014) Rita de Cassia dos Santos Ferreira et al. BMC INFECTIOUS DISEASES
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- (2014) Grégoire Lauvau et al. CELLULAR IMMUNOLOGY
- Up-regulation of Thrombospondin-2 in Akt1-null Mice Contributes to Compromised Tissue Repair Due to Abnormalities in Fibroblast Function
- (2014) Tara Bancroft et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Current understanding of the thrombospondin-1 interactome
- (2014) Andrea Resovi et al. MATRIX BIOLOGY
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- (2014) David R. Soto-Pantoja et al. MATRIX BIOLOGY
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- (2014) Kevin M. Vannella et al. PLoS Pathogens
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- Cellular, Pharmacological, and Biophysical Evaluation of Explanted Lungs from a Patient with Sickle Cell Disease and Severe Pulmonary Arterial Hypertension
- (2014) Natasha M. Rogers et al. Pulmonary Circulation
- Protective Role of IL-6 in Vascular Remodeling inSchistosomaPulmonary Hypertension
- (2013) Brian B. Graham et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- TGF-β Activation and Function in Immunity
- (2013) Mark A. Travis et al. Annual Review of Immunology
- Transforming Growth Factor-β Signaling Promotes Pulmonary Hypertension Caused by Schistosoma Mansoni
- (2013) Brian B. Graham et al. CIRCULATION
- Unchaining the beast; insights from structural and evolutionary studies on TGFβ secretion, sequestration, and activation
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- The role of thrombospondin-1 in cardiovascular health and pathology
- (2013) Smriti Murali Krishna et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Relevant Issues in the Pathology and Pathobiology of Pulmonary Hypertension
- (2013) Rubin M. Tuder et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
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- (2013) Gerald Simonneau et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Long-Term Gene Therapy with Thrombospondin 2 Inhibits TGF-β Activation, Inflammation and Angiogenesis in Chronic Allograft Nephropathy
- (2013) Christoph Daniel et al. PLoS One
- The Schistosoma Granuloma: Friend or Foe?
- (2013) Emily Hams et al. Frontiers in Immunology
- Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1
- (2012) Philip M. Bauer et al. CARDIOVASCULAR RESEARCH
- Significant Intrapulmonary Schistosoma Egg Antigens are not Present in Schistosomiasis-Associated Pulmonary Hypertension
- (2012) Brian B. Graham et al. Pulmonary Circulation
- Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Regulates Thrombospondin-1 and Nox4 Expression in Hypoxia-Induced Human Pulmonary Artery Smooth Muscle Cell Proliferation
- (2012) David E. Green et al. Pulmonary Circulation
- Blockade of TSP1-Dependent TGF-β Activity Reduces Renal Injury and Proteinuria in a Murine Model of Diabetic Nephropathy
- (2011) Ailing Lu et al. AMERICAN JOURNAL OF PATHOLOGY
- Loss-of-function thrombospondin-1 mutations in familial pulmonary hypertension
- (2011) James P. Maloney et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
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- (2011) Caio J.C.S. Fernandes et al. CHEST
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- (2011) Hiromitsu Hayashi et al. HEPATOLOGY
- Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease
- (2011) Wanli Ma et al. JOURNAL OF CLINICAL INVESTIGATION
- Emergence of Fibroblasts with a Proinflammatory Epigenetically Altered Phenotype in Severe Hypoxic Pulmonary Hypertension
- (2011) M. Li et al. JOURNAL OF IMMUNOLOGY
- Schistosomiasis-Induced Experimental Pulmonary Hypertension
- (2010) Brian B. Graham et al. AMERICAN JOURNAL OF PATHOLOGY
- Thrombospondin-1 null mice are resistant to hypoxia-induced pulmonary hypertension
- (2010) Cristhiaan D Ochoa et al. Journal of Cardiothoracic Surgery
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- Hypoxia exposure induces the emergence of fibroblasts lacking replication repressor signals of PKC in the pulmonary artery adventitia
- (2008) M. Das et al. CARDIOVASCULAR RESEARCH
- Helminth infections: the great neglected tropical diseases
- (2008) Peter J. Hotez et al. JOURNAL OF CLINICAL INVESTIGATION
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