BMPR2‐expressing bone marrow‐derived endothelial‐like progenitor cells alleviate pulmonary arterial hypertension in vivo

New and Emerging Therapies for Pulmonary Arterial Hypertension

(2018) Edda Spiekerkoetter et al.   Annual Review of Medicine

Randomised placebo-controlled safety and tolerability trial of FK506 (tacrolimus) for pulmonary arterial hypertension

(2017) Edda Spiekerkoetter et al.   EUROPEAN RESPIRATORY JOURNAL

Exosomes induce and reverse monocrotaline-induced pulmonary hypertension in mice

(2016) Jason M. Aliotta et al.   CARDIOVASCULAR RESEARCH

BMPR2 gene therapy for PAH acts via Smad and non-Smad signalling

(2016) Rebecca L. Harper et al.   RESPIROLOGY

Endothelial NO-Synthase Gene-Enhanced Progenitor Cell Therapy for Pulmonary Arterial HypertensionNovelty and Significance

(2015) John Granton et al.   CIRCULATION RESEARCH

Sphingosine 1-phosphate is a ligand for peroxisome proliferator-activated receptor-γ that regulates neoangiogenesis

(2015) Kate A. Parham et al.   FASEB JOURNAL

Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension

(2015) Lu Long et al.   NATURE MEDICINE

BMPR2 gene delivery reduces mutation-related PAH and counteracts TGF-β-mediated pulmonary cell signalling

(2015) Feng Feng et al.   RESPIROLOGY

Endothelial progenitor cells: novel biomarker and promising cell therapy for cardiovascular disease

(2015) Shaundeep Sen et al.   CLINICAL SCIENCE

Therapeutic effects of mesenchymal stem cell-derived microvesicles on pulmonary arterial hypertension in rats

(2014) Jian-ying Chen et al.   ACTA PHARMACOLOGICA SINICA

FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension

(2013) Edda Spiekerkoetter et al.   JOURNAL OF CLINICAL INVESTIGATION

Exosomes Mediate the Cytoprotective Action of Mesenchymal Stromal Cells on Hypoxia-Induced Pulmonary Hypertension

(2012) Changjin Lee et al.   CIRCULATION

Mesenchymal stem cell prevention of vascular remodeling in high flow-induced pulmonary hypertension through a paracrine mechanism

(2012) Yun Luan et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Establishment of outgrowth endothelial cells from peripheral blood

(2012) Javier Martin-Ramirez et al.   Nature Protocols

Targeted gene delivery of BMPR2 attenuates pulmonary hypertension

(2011) A. M. Reynolds et al.   EUROPEAN RESPIRATORY JOURNAL

Incorporation of endothelial progenitor cells into mosaic pseudoislets

(2011) Daniella Penko et al.   Islets

Survival in Patients With Idiopathic, Familial, and Anorexigen-Associated Pulmonary Arterial Hypertension in the Modern Management Era

(2010) Marc Humbert et al.   CIRCULATION

Altered Bone Morphogenetic Protein and Transforming Growth Factor-β Signaling in Rat Models of Pulmonary Hypertension

(2009) Lu Long et al.   CIRCULATION

TGF-β and BMPR-II pharmacology—implications for pulmonary vascular diseases

(2009) Paul D Upton et al.   CURRENT OPINION IN PHARMACOLOGY