TGF ‐β as a driver of fibrosis: physiological roles and therapeutic opportunities
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
TGF
‐β as a driver of fibrosis: physiological roles and therapeutic opportunities
Authors
Keywords
-
Journal
JOURNAL OF PATHOLOGY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2021-04-09
DOI
10.1002/path.5680
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Epithelial plasticity, epithelial-mesenchymal transition, and the TGF-β family
- (2021) Yoko Katsuno et al. DEVELOPMENTAL CELL
- Hiding in Plain Sight: Interleukin-11 Emerges as a Master Regulator of Fibrosis, Tissue Integrity, and Stromal Inflammation
- (2020) Stuart A. Cook et al. Annual Review of Medicine
- TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency
- (2020) Haiyun Chen et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Development of an oral bentonite-based modified-release freeze-dried powder of vactosertib: Pharmacokinetics and anti-colitis activity in rodent models of ulcerative colitis
- (2020) Su Young Jung et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Transforming growth factor–β in tissue fibrosis
- (2020) Nikolaos G. Frangogiannis JOURNAL OF EXPERIMENTAL MEDICINE
- Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-β
- (2020) Alessandra Metelli et al. Science Translational Medicine
- A Potent Pan-TGFβ Neutralizing Monoclonal Antibody Elicits Cardiovascular Toxicity in Mice and Cynomolgus Monkeys
- (2020) Mayur S Mitra et al. TOXICOLOGICAL SCIENCES
- Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair
- (2020) Filipa C. Simões et al. Nature Communications
- Liver Fibrosis and Inflammation under the Control of ERK2
- (2020) Kuo-Shyang Jeng et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Reversal of TGFβ1-Driven Profibrotic State in Patients with Pulmonary Fibrosis
- (2020) Harold A. Chapman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape
- (2020) Constance J. Martin et al. Science Translational Medicine
- Human Liver Spheroids as a Model to Study Aetiology and Treatment of Hepatic Fibrosis
- (2020) Tracey Hurrell et al. Cells
- TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering
- (2020) Jin Ma et al. Frontiers in Cell and Developmental Biology
- Fibroblast-specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease
- (2020) Benjamin Ng et al. FASEB JOURNAL
- TGFβ biology in cancer progression and immunotherapy
- (2020) Rik Derynck et al. Nature Reviews Clinical Oncology
- Occupational and environmental risk factors for idiopathic pulmonary fibrosis in Australia: case–control study
- (2020) Michael J Abramson et al. THORAX
- Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity
- (2020) Lu Cui et al. Nature Communications
- Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis
- (2020) Arun C. Habermann et al. Science Advances
- p38 MAPK Pathway in the Heart: New Insights in Health and Disease
- (2020) Rafael Romero-Becerra et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Spectrum of Fibrotic Lung Diseases
- (2020) Marlies Wijsenbeek et al. NEW ENGLAND JOURNAL OF MEDICINE
- Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis
- (2020) Alison E. John et al. Nature Communications
- Myh11+ microvascular mural cells and derived mesenchymal stem cells promote retinal fibrosis
- (2020) H. Clifton Ray et al. Scientific Reports
- The promise of mTOR as a therapeutic target pathway in idiopathic pulmonary fibrosis
- (2020) Manuela Platé et al. European Respiratory Review
- Inhibition of TGFβ1 and TGFβ3 promotes hematopoiesis in Fanconi anemia
- (2020) Alfredo Rodríguez et al. EXPERIMENTAL HEMATOLOGY
- The Epithelial-to-Mesenchymal Transition as a Possible Therapeutic Target in Fibrotic Disorders
- (2020) Jacopo Di Gregorio et al. Frontiers in Cell and Developmental Biology
- Specificity, versatility, and control of TGF-β family signaling
- (2019) Rik Derynck et al. Science Signaling
- Macrophage Smad3 Protects the Infarcted Heart, Stimulating Phagocytosis and Regulating Inflammation
- (2019) Bijun Chen et al. CIRCULATION RESEARCH
- LOXL2—A New Target in Antifibrogenic Therapy?
- (2019) Angela Puente et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β1–induced collagen biosynthesis
- (2019) Brintha Selvarajah et al. Science Signaling
- Pharmacokinetic characteristics of vactosertib, a new activin receptor-like kinase 5 inhibitor, in patients with advanced solid tumors in a first-in-human phase 1 study
- (2019) Su Young Jung et al. INVESTIGATIONAL NEW DRUGS
- Inhibition of hyperglycolysis in mesothelial cells prevents peritoneal fibrosis
- (2019) Meijun Si et al. Science Translational Medicine
- Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis
- (2019) Benjamin Ng et al. Science Translational Medicine
- Integrin-Mediated TGFβ Activation Modulates the Tumour Microenvironment
- (2019) Brown et al. Cancers
- Fibroblasts and Their Pathological Functions in the Fibrosis of Aortic Valve Sclerosis and Atherosclerosis
- (2019) Singh et al. Biomolecules
- Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis
- (2019) Richard J Allen et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Small airway fibrosis in COPD
- (2019) Peter J. Barnes INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Shared and distinct mechanisms of fibrosis
- (2019) Jörg H. W. Distler et al. Nature Reviews Rheumatology
- LRRC33 is a novel binding and potential regulating protein of TGF-β1 function in human acute myeloid leukemia cells
- (2019) Wenjiang Ma et al. PLoS One
- Evasion of apoptosis by myofibroblasts: a hallmark of fibrotic diseases
- (2019) Boris Hinz et al. Nature Reviews Rheumatology
- Hexokinase 2 couples glycolysis with the profibrotic actions of TGF-β
- (2019) Xueqian Yin et al. Science Signaling
- TGF-β in fibrosis by acting as a conductor for contractile properties of myofibroblasts
- (2019) Alexandre Vallée et al. Cell and Bioscience
- An αv-RGD Integrin Inhibitor Toolbox: Drug Discovery Insight, Challenges and Opportunities
- (2018) Richard J. D. Hatley et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Mechanisms of Renal Fibrosis
- (2018) Benjamin D. Humphreys Annual Review of Physiology
- Inhibition of mTOR ameliorates bleomycin-induced pulmonary fibrosis by regulating epithelial-mesenchymal transition
- (2018) Qian Han et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- LRRC15 Is a Novel Mesenchymal Protein and Stromal Target for Antibody–Drug Conjugates
- (2018) James W. Purcell et al. CANCER RESEARCH
- A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System
- (2018) Yan Qin et al. CELL
- Phase I Trial of M7824 (MSB0011359C), a Bifunctional Fusion Protein Targeting PD-L1 and TGFβ, in Advanced Solid Tumors
- (2018) Julius Strauss et al. CLINICAL CANCER RESEARCH
- The Role of the Mammalian Target of Rapamycin (mTOR) in Pulmonary Fibrosis
- (2018) Jessica Lawrence et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Determinants of fibrosis progression and regression in NASH
- (2018) Detlef Schuppan et al. JOURNAL OF HEPATOLOGY
- Resident fibroblast expansion during cardiac growth and remodeling
- (2018) Malina J. Ivey et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Idiopathic Pulmonary Fibrosis
- (2018) David J. Lederer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Enhanced preclinical antitumor activity of M7824, a bifunctional fusion protein simultaneously targeting PD-L1 and TGF-β
- (2018) Yan Lan et al. Science Translational Medicine
- Absence of Myocardial Fibrosis Predicts Favorable Long-Term Survival in New-Onset Heart Failure
- (2018) Ankur Gulati et al. Circulation-Cardiovascular Imaging
- Burden of Liver Diseases in the World
- (2018) Sumeet K. Asrani et al. JOURNAL OF HEPATOLOGY
- Molecular characterization of a precision-cut rat liver slice model for the evaluation of antifibrotic compounds
- (2018) Xinqiang Huang et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- EW-7197 prevents ulcerative colitis-associated fibrosis and inflammation
- (2018) Maryam M. Binabaj et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis
- (2018) Hannah V. Woodcock et al. Nature Communications
- Regression of liver fibrosis over a 24-week period after completing direct-acting antiviral therapy in patients with chronic hepatitis C receiving care within the national hepatitis C elimination program in Georgia
- (2017) Ekaterine Dolmazashvili et al. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
- Mechanisms, Management, and Treatment of Fibrosis in Patients With Inflammatory Bowel Diseases
- (2017) Florian Rieder et al. GASTROENTEROLOGY
- TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases
- (2017) Evangelia Pardali et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- TGFβ signaling and the control of myofibroblast differentiation: Implications for chronic inflammatory disorders
- (2017) Jonathon M. Carthy JOURNAL OF CELLULAR PHYSIOLOGY
- Fibroblast-specific inhibition of TGF-β1 signaling attenuates lung and tumor fibrosis
- (2017) Ying Wei et al. JOURNAL OF CLINICAL INVESTIGATION
- Rictor/mammalian target of rapamycin complex 2 promotes macrophage activation and kidney fibrosis
- (2017) Jiafa Ren et al. JOURNAL OF PATHOLOGY
- Role of GARP in the activation of latent TGF-β1
- (2017) Julie Stockis et al. Molecular BioSystems
- Unifying mechanism for different fibrotic diseases
- (2017) Gerlinde Wernig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Blocking immunosuppression by human Tregs in vivo with antibodies targeting integrin αVβ8
- (2017) Julie Stockis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TGF-β1 Signaling and Tissue Fibrosis
- (2017) Kevin K. Kim et al. Cold Spring Harbor Perspectives in Biology
- TGF-β Signaling in Control of Cardiovascular Function
- (2017) Marie-José Goumans et al. Cold Spring Harbor Perspectives in Biology
- Preclinical assessment of galunisertib (LY2157299 monohydrate), a first-in-class transforming growth factor-β receptor type I inhibitor
- (2017) Jonathan M. Yingling et al. Oncotarget
- Drugs and Targets in Fibrosis
- (2017) Xiaoyi Li et al. Frontiers in Pharmacology
- The Processes and Mechanisms of Cardiac and Pulmonary Fibrosis
- (2017) Lucy A. Murtha et al. Frontiers in Physiology
- Epithelial-mesenchymal transition in tissue repair and fibrosis
- (2016) Rivka C. Stone et al. CELL AND TISSUE RESEARCH
- αv integrins: key regulators of tissue fibrosis
- (2016) Kylie P. Conroy et al. CELL AND TISSUE RESEARCH
- Profibrotic up-regulation of glucose transporter 1 by TGF-β involves activation of MEK and mammalian target of rapamycin complex 2 pathways
- (2016) Mahefatiana Andrianifahanana et al. FASEB JOURNAL
- Lysyl oxidase activity contributes to collagen stabilization during liver fibrosis progression and limits spontaneous fibrosis reversal in mice
- (2016) Susan B. Liu et al. FASEB JOURNAL
- Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood
- (2016) Martin L. Decaris et al. HEPATOLOGY
- Macrophages in Tissue Repair, Regeneration, and Fibrosis
- (2016) Thomas A. Wynn et al. IMMUNITY
- Myofibroblast repair mechanisms post-inflammatory response: a fibrotic perspective
- (2016) Casimiro Gerarduzzi et al. INFLAMMATION RESEARCH
- Anti–TGF-β1 Antibody Therapy in Patients with Diabetic Nephropathy
- (2016) James Voelker et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease
- (2016) Sun-Gou Ji et al. NATURE GENETICS
- TGF-β: the master regulator of fibrosis
- (2016) Xiao-ming Meng et al. Nature Reviews Nephrology
- Roles of mTOR complexes in the kidney: implications for renal disease and transplantation
- (2016) Daniel Fantus et al. Nature Reviews Nephrology
- Anti-TGF-β Antibody, 1D11, Ameliorates Glomerular Fibrosis in Mouse Models after the Onset of Proteinuria
- (2016) Xiaoyan Liang et al. PLoS One
- Transcriptional Control by the SMADs
- (2016) Caroline S. Hill Cold Spring Harbor Perspectives in Biology
- Signaling Receptors for TGF-β Family Members
- (2016) Carl-Henrik Heldin et al. Cold Spring Harbor Perspectives in Biology
- TGF-β Signaling from Receptors to Smads
- (2016) Akiko Hata et al. Cold Spring Harbor Perspectives in Biology
- Non-Smad Signaling Pathways of the TGF-β Family
- (2016) Ying E. Zhang Cold Spring Harbor Perspectives in Biology
- Posttranslational Regulation of Smads
- (2016) Pinglong Xu et al. Cold Spring Harbor Perspectives in Biology
- TGF-β Family Signaling in the Control of Cell Proliferation and Survival
- (2016) Yun Zhang et al. Cold Spring Harbor Perspectives in Biology
- Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins
- (2016) Ian B. Robertson et al. Cold Spring Harbor Perspectives in Biology
- TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology
- (2016) Masato Morikawa et al. Cold Spring Harbor Perspectives in Biology
- Genetic lineage tracing defines myofibroblast origin and function in the injured heart
- (2016) Onur Kanisicak et al. Nature Communications
- Cutaneous keratoacanthomas/squamous cell carcinomas associated with neutralization of transforming growth factor β by the monoclonal antibody fresolimumab (GC1008)
- (2015) Mario E. Lacouture et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- The role of tyrosine kinases in the pathogenesis of idiopathic pulmonary fibrosis
- (2015) Friedrich Grimminger et al. EUROPEAN RESPIRATORY JOURNAL
- Integrin αvβ6 critically regulates hepatic progenitor cell function and promotes ductular reaction, fibrosis, and tumorigenesis
- (2015) Zhen-Wei Peng et al. HEPATOLOGY
- Fresolimumab treatment decreases biomarkers and improves clinical symptoms in systemic sclerosis patients
- (2015) Lisa M. Rice et al. JOURNAL OF CLINICAL INVESTIGATION
- Rictor/mTORC2 signaling mediates TGFβ1-induced fibroblast activation and kidney fibrosis
- (2015) Jianzhong Li et al. KIDNEY INTERNATIONAL
- Development and characterization of human monoclonal antibodies that neutralize multiple TGFβ isoforms
- (2015) Daniel Bedinger et al. mAbs
- The α v β 1 integrin plays a critical in vivo role in tissue fibrosis
- (2015) Nilgun I. Reed et al. Science Translational Medicine
- TGF-β1 Up-Regulates Connective Tissue Growth Factor Expression in Human Granulosa Cells through Smad and ERK1/2 Signaling Pathways
- (2015) Jung-Chien Cheng et al. PLoS One
- Cardiac Safety of TGF-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Cancer Patients in a First-in-Human Dose Study
- (2014) Richard J. Kovacs et al. Cardiovascular Toxicology
- EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-β/Smad and ROS signaling
- (2014) Sang-A Park et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Macrophages Produce TGF- -Induced ( -ig-h3) following Ingestion of Apoptotic Cells and Regulate MMP14 Levels and Collagen Turnover in Fibroblasts
- (2014) N. Nacu et al. JOURNAL OF IMMUNOLOGY
- Fibrosis—a lethal component of systemic sclerosis
- (2014) Yuen Yee Ho et al. Nature Reviews Rheumatology
- Phase I Study of GC1008 (Fresolimumab): A Human Anti-Transforming Growth Factor-Beta (TGFβ) Monoclonal Antibody in Patients with Advanced Malignant Melanoma or Renal Cell Carcinoma
- (2014) John C. Morris et al. PLoS One
- Mechanisms of initiation and progression of intestinal fibrosis in IBD
- (2014) Giovanni Latella et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- Selective Targeting of TGF- Activation to Treat Fibroinflammatory Airway Disease
- (2014) S. Minagawa et al. Science Translational Medicine
- Fibroblasts in fibrosis: novel roles and mediators
- (2014) Ryan T. Kendall et al. Frontiers in Pharmacology
- Tissue mechanics and fibrosis
- (2013) Rebecca G. Wells BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The pathogenesis of cardiac fibrosis
- (2013) Ping Kong et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The fibroproliferative response in acute respiratory distress syndrome: mechanisms and clinical significance
- (2013) E. L. Burnham et al. EUROPEAN RESPIRATORY JOURNAL
- Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis
- (2013) Tasha E Fingerlin et al. NATURE GENETICS
- Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs
- (2013) Neil C Henderson et al. NATURE MEDICINE
- Bleomycin Induces Molecular Changes Directly Relevant to Idiopathic Pulmonary Fibrosis: A Model for “Active” Disease
- (2013) Ruoqi Peng et al. PLoS One
- mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin
- (2013) S. A. Kang et al. SCIENCE
- Integrin-mediated regulation of TGFβ in fibrosis
- (2012) Neil C. Henderson et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Tyrosine kinase signaling in fibrotic disorders
- (2012) Christian Beyer et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- Pulmonary fibrosis: patterns and perpetrators
- (2012) Paul W. Noble et al. JOURNAL OF CLINICAL INVESTIGATION
- Deleting the TGF- Receptor Attenuates Acute Proximal Tubule Injury
- (2012) L. Gewin et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Engineering and Therapeutic Application of Single-Chain Bivalent TGF- Family Traps
- (2012) J. C. Zwaagstra et al. MOLECULAR CANCER THERAPEUTICS
- TGFβ signalling in context
- (2012) Joan Massagué NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Rapamycin Ameliorates Kidney Fibrosis by Inhibiting the Activation of mTOR Signaling in Interstitial Macrophages and Myofibroblasts
- (2012) Guochun Chen et al. PLoS One
- Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity
- (2012) D. W. Lamming et al. SCIENCE
- TGF-β Signaling via TAK1 Pathway: Role in Kidney Fibrosis
- (2012) Mary E. Choi et al. SEMINARS IN NEPHROLOGY
- MEK-ERK Pathway Modulation Ameliorates Pulmonary Fibrosis Associated with Epidermal Growth Factor Receptor Activation
- (2011) Satish K. Madala et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Structures of TGF-β Receptor Complexes: Implications for Function and Therapeutic Intervention Using Ligand Traps
- (2011) Andrew P. Hinck et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Myofibroblast differentiation and survival in fibrotic disease
- (2011) Kornelia Kis et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9
- (2011) Marcel Janse et al. HEPATOLOGY
- Transforming growth factor-beta type 1 receptor (ALK5) and Smad proteins mediate TIMP-1 and collagen synthesis in experimental intestinal fibrosis
- (2011) Carlos Medina et al. JOURNAL OF PATHOLOGY
- Diverse roles of TGF-β receptor II in renal fibrosis and inflammation in vivo and in vitro
- (2011) Xiao-Ming Meng et al. JOURNAL OF PATHOLOGY
- Inhibition of the p38 MAPK pathway ameliorates renal fibrosis in an NPHP2 mouse model
- (2011) Noriyuki Sugiyama et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Induction of Heart Valve Lesions by Small-Molecule ALK5 Inhibitors
- (2011) Mark J. Anderton et al. TOXICOLOGIC PATHOLOGY
- Targeted inhibition of activin receptor-like kinase 5 signaling attenuates cardiac dysfunction following myocardial infarction
- (2010) Sih Min Tan et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Cell Signaling by Receptor Tyrosine Kinases
- (2010) Mark A. Lemmon et al. CELL
- Smad2 Protects against TGF- /Smad3-Mediated Renal Fibrosis
- (2010) X. M. Meng et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Connective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animals
- (2009) David R. Brigstock Journal of Cell Communication and Signaling
- SM16, an Orally Active TGF-β Type I Receptor Inhibitor Prevents Myofibroblast Induction and Vascular Fibrosis in the Rat Carotid Injury Model
- (2008) Kai Fu et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Antibody-Mediated Blockade of Integrin v 6 Inhibits Tumor Progression In vivo by a Transforming Growth Factor- Regulated Mechanism
- (2008) L. A. Koopman Van Aarsen et al. CANCER RESEARCH
- 1 Integrin Inhibition Dramatically Enhances Radiotherapy Efficacy in Human Breast Cancer Xenografts
- (2008) C. C. Park et al. CANCER RESEARCH
- Inhibition of Integrin αvβ6 on Cholangiocytes Blocks Transforming Growth Factor-β Activation and Retards Biliary Fibrosis Progression
- (2008) Eleonora Patsenker et al. GASTROENTEROLOGY
- Evidence for Activation of the TGF-β1 Promoter by C/EBPβ and Its Modulation by Smads
- (2008) Selvajothi Abraham et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
- (2008) A. Y. Choo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PERSPECTIVE ARTICLE: Growth factors and cytokines in wound healing
- (2008) Stephan Barrientos et al. WOUND REPAIR AND REGENERATION
- Inhibition of Integrin αvβ6, an Activator of Latent Transforming Growth Factor-β, Prevents Radiation-induced Lung Fibrosis
- (2007) Khalid Puthawala et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Partial Inhibition of Integrin αvβ6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation
- (2007) Gerald S. Horan et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Cellular and molecular mechanisms of fibrosis
- (2007) TA Wynn JOURNAL OF PATHOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now