A disease-associated frameshift mutation in caveolin-1 disrupts caveolae formation and function through introduction of a de novo ER retention signal

Aberrant caveolin-1–mediated Smad signaling and proliferation identified by analysis of adenine 474 deletion mutation (c.474delA) in patient fibroblasts: a new perspective on the mechanism of pulmonary hypertension

(2017) Glenn Marsboom et al.   MOLECULAR BIOLOGY OF THE CELL

Characterization of a caveolin-1 mutation associated with both pulmonary arterial hypertension and congenital generalized lipodystrophy

(2016) Bing Han et al.   TRAFFIC

Caveolae: One Function or Many?

(2016) Jade P.X. Cheng et al.   TRENDS IN CELL BIOLOGY

Caveolin-1 is an aggresome-inducing protein

(2016) Ajit Tiwari et al.   Scientific Reports

Whole exome sequencing identifies de novo heterozygousCAV1mutations associated with a novel neonatal onset lipodystrophy syndrome

(2015) Abhimanyu Garg et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Epigenetic modifications of caveolae associated proteins in health and disease

(2015) Jin-Yih Low et al.   BMC GENETICS

Caveolae protect endothelial cells from membrane rupture during increased cardiac output

(2015) Jade P.X. Cheng et al.   JOURNAL OF CELL BIOLOGY

Cavin family proteins and the assembly of caveolae

(2015) O. Kovtun et al.   JOURNAL OF CELL SCIENCE

A Frame-Shift Mutation in CAV1 Is Associated with a Severe Neonatal Progeroid and Lipodystrophy Syndrome

(2015) Isabelle Schrauwen et al.   PLoS One

Tagging Strategies Strongly Affect the Fate of Overexpressed Caveolin-1

(2015) Bing Han et al.   TRAFFIC

PTRF/Cavin-1 decreases prostate cancer angiogenesis and lymphangiogenesis

(2015) Zeyad D Nassar et al.   Oncotarget

The Genetics of Pulmonary Arterial Hypertension

(2014) Eric D. Austin et al.   CIRCULATION RESEARCH

Heterozygous Null Bone Morphogenetic Protein Receptor Type 2 Mutations Promote SRC Kinase-dependent Caveolar Trafficking Defects and Endothelial Dysfunction in Pulmonary Arterial Hypertension

(2014) Allison R. Prewitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endocytic Crosstalk: Cavins, Caveolins, and Caveolae Regulate Clathrin-Independent Endocytosis

(2014) Natasha Chaudhary et al.   PLOS BIOLOGY

Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae

(2014) Yann Gambin et al.   eLife

Nitrosation-Dependent Caveolin 1 Phosphorylation, Ubiquitination, and Degradation and its Association with Idiopathic Pulmonary Arterial Hypertension

(2014) Farnaz R. Bakhshi et al.   Pulmonary Circulation

SnapShot: Caveolae, Caveolins, and Cavins

(2013) Nicholas Ariotti et al.   CELL

Definitions and Diagnosis of Pulmonary Hypertension

(2013) Marius M. Hoeper et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Caveolae as plasma membrane sensors, protectors and organizers

(2013) Robert G. Parton et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Overexpression of Caveolin-1 Is Sufficient to Phenocopy the Behavior of a Disease-Associated Mutant

(2013) Caroline A. Hanson et al.   TRAFFIC

Molecular Composition and Ultrastructure of the Caveolar Coat Complex

(2013) Alexander Ludwig et al.   PLOS BIOLOGY

Whole Exome Sequencing to Identify a Novel Gene (Caveolin-1) Associated With Human Pulmonary Arterial Hypertension

(2012) Eric D. Austin et al.   Circulation-Cardiovascular Genetics

Structure-Based Reassessment of the Caveolin Signaling Model: Do Caveolae Regulate Signaling through Caveolin-Protein Interactions?

(2012) Brett M. Collins et al.   DEVELOPMENTAL CELL

Oligomers of the ATPase EHD2 confine caveolae to the plasma membrane through association with actin

(2012) Miriam Stoeber et al.   EMBO JOURNAL

EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization

(2012) Björn Morén et al.   MOLECULAR BIOLOGY OF THE CELL

Stressing caveolae new role in cell mechanics

(2012) Pierre Nassoy et al.   TRENDS IN CELL BIOLOGY

Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae

(2011) Bidisha Sinha et al.   CELL

Pacsin 2 is recruited to caveolae and functions in caveolar biogenesis

(2011) C. G. Hansen et al.   JOURNAL OF CELL SCIENCE

Essential role of PACSIN2/syndapin-II in caveolae membrane sculpting

(2011) Y. Senju et al.   JOURNAL OF CELL SCIENCE

Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation

(2010) Arnold Hayer et al.   JOURNAL OF CELL BIOLOGY

Quantitative Proteomics of Caveolin-1-regulated Proteins

(2010) Alberto Dávalos et al.   MOLECULAR & CELLULAR PROTEOMICS

Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration

(2009) You-Yang Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

Biogenesis of Caveolae: Stepwise Assembly of Large Caveolin and Cavin Complexes

(2009) Arnold Hayer et al.   TRAFFIC

PTRF-Cavin, a Conserved Cytoplasmic Protein Required for Caveola Formation and Function

(2008) Michelle M. Hill et al.   CELL

Deletion of Cavin/PTRF Causes Global Loss of Caveolae, Dyslipidemia, and Glucose Intolerance

(2008) Libin Liu et al.   Cell Metabolism

Evolutionary analysis and molecular dissection of caveola biogenesis

(2008) M. Kirkham et al.   JOURNAL OF CELL SCIENCE