An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension
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Title
An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension
Authors
Keywords
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Journal
Nature Communications
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-03-19
DOI
10.1038/s41467-021-21961-3
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Note: Only part of the references are listed.- Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension
- (2019) Ly Tu et al. CIRCULATION RESEARCH
- A Potential Role for Exosomal TCTP Export in Vascular Remodeling in Pulmonary Arterial Hypertension
- (2018) Elisabet Ferrer et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- BMPR2 inhibits activin and BMP signaling via wild-type ALK2
- (2018) Oddrun Elise Olsen et al. JOURNAL OF CELL SCIENCE
- Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension
- (2018) Yuichi Tamura et al. JOURNAL OF CLINICAL INVESTIGATION
- Bone morphogenetic protein receptor signal transduction in human diseases
- (2018) Maria Catalina Gomez-Puerto et al. JOURNAL OF PATHOLOGY
- An overview of the 6th World Symposium on Pulmonary Hypertension
- (2018) Nazzareno Galiè et al. EUROPEAN RESPIRATORY JOURNAL
- Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives
- (2018) Marc Humbert et al. EUROPEAN RESPIRATORY JOURNAL
- Haemodynamic definitions and updated clinical classification of pulmonary hypertension
- (2018) Gérald Simonneau et al. EUROPEAN RESPIRATORY JOURNAL
- Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone
- (2018) Andrea Iskenderian et al. Skeletal Muscle
- Epidemiology and treatment of pulmonary arterial hypertension
- (2017) Edmund M. T. Lau et al. Nature Reviews Cardiology
- TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling
- (2017) Liam A. Hurst et al. Nature Communications
- Pulmonary vascular remodeling in pulmonary hypertension
- (2016) Rubin M. Tuder CELL AND TISSUE RESEARCH
- Activin-A is overexpressed in severe asthma and is implicated in angiogenic processes
- (2016) Konstantinos Samitas et al. EUROPEAN RESPIRATORY JOURNAL
- Transforming Growth Factor-β Family Ligands Can Function as Antagonists by Competing for Type II Receptor Binding
- (2016) Senem Aykul et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension
- (2016) Christophe Guignabert et al. JOURNAL OF CLINICAL INVESTIGATION
- Differential regulation of translation and endocytosis of alternatively spliced forms of the type II bone morphogenetic protein (BMP) receptor
- (2016) Ayelet R. Amsalem et al. MOLECULAR BIOLOGY OF THE CELL
- BMPR2 mutations and survival in pulmonary arterial hypertension: an individual participant data meta-analysis
- (2016) Jonathan D W Evans et al. Lancet Respiratory Medicine
- Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex
- (2015) Morane Le Hiress et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Impaired Bone Morphogenetic Protein Receptor II Signaling in a Transforming Growth Factor-β–Dependent Mouse Model of Pulmonary Hypertension and in Systemic Sclerosis
- (2015) Adrian J. Gilbane et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- New Molecular Targets of Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension
- (2015) Christophe Guignabert et al. CHEST
- Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension
- (2015) Lu Long et al. NATURE MEDICINE
- The Role of Vascular Endothelial Growth Factor in Pulmonary Arterial Hypertension. The Angiogenesis Paradox
- (2014) Norbert F. Voelkel et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Advances in Therapeutic Interventions for Patients With Pulmonary Arterial Hypertension
- (2014) Marc Humbert et al. CIRCULATION
- Heterozygous Null Bone Morphogenetic Protein Receptor Type 2 Mutations Promote SRC Kinase-dependent Caveolar Trafficking Defects and Endothelial Dysfunction in Pulmonary Arterial Hypertension
- (2014) Allison R. Prewitt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Non-specificity of Pitstop 2 in clathrin-mediated endocytosis
- (2014) A. K. Willox et al. Biology Open
- Evidence for the Involvement of Type I Interferon in Pulmonary Arterial Hypertension
- (2013) Peter M. George et al. CIRCULATION RESEARCH
- The lysosomal inhibitor, chloroquine, increases cell surface BMPR-II levels and restores BMP9 signalling in endothelial cells harbouring BMPR-II mutations
- (2013) B. J. Dunmore et al. HUMAN MOLECULAR GENETICS
- Abnormal Trafficking of Endogenously Expressed BMPR2 Mutant Allelic Products in Patients with Heritable Pulmonary Arterial Hypertension
- (2013) Andrea L. Frump et al. PLoS One
- Tie2-dependent knockout of α6 integrin subunit in mice reduces post-ischaemic angiogenesis
- (2012) Claire Bouvard et al. CARDIOVASCULAR RESEARCH
- Structural studies of the TGF-βs and their receptors - insights into evolution of the TGF-β superfamily
- (2012) Andrew P. Hinck FEBS LETTERS
- The bright and the dark sides of activin in wound healing and cancer
- (2012) Maria Antsiferova et al. JOURNAL OF CELL SCIENCE
- Plexiform Lesions in Pulmonary Arterial Hypertension
- (2011) Danny Jonigk et al. AMERICAN JOURNAL OF PATHOLOGY
- Activin A inhibits vascular endothelial cell growth and suppresses tumour angiogenesis in gastric cancer
- (2011) H Kaneda et al. BRITISH JOURNAL OF CANCER
- The Genetics of Pulmonary Arterial Hypertension in the Post-BMPR2 Era
- (2011) Joshua P. Fessel et al. Pulmonary Circulation
- Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT)
- (2009) et al. EUROPEAN HEART JOURNAL
- Genetics and Genomics of Pulmonary Arterial Hypertension
- (2009) Rajiv D. Machado et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Failure of bone morphogenetic protein receptor trafficking in pulmonary arterial hypertension: potential for rescue
- (2008) A. Sobolewski et al. HUMAN MOLECULAR GENETICS
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