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Title
The P2X7 Receptor: Central Hub of Brain Diseases
Authors
Keywords
-
Journal
Frontiers in Molecular Neuroscience
Volume 13, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-07-31
DOI
10.3389/fnmol.2020.00124
References
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- (2009) Elaine K. Green et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Variation inP2RX7candidate gene (rs2230912) is not associated with bipolar I disorder and unipolar major depression in four European samples
- (2009) Maria Grigoroiu-Serbanescu et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- The antihyperalgesic activity of a selective P2X7 receptor antagonist, A-839977, is lost in IL-1αβ knockout mice
- (2009) Prisca Honore et al. BEHAVIOURAL BRAIN RESEARCH
- Acid sphingomyelinase activity triggers microparticle release from glial cells
- (2009) Fabio Bianco et al. EMBO JOURNAL
- Altered P2X7-receptor level and function in mouse models of Huntington’s disease and therapeutic efficacy of antagonist administration
- (2009) Miguel Díaz-Hernández et al. FASEB JOURNAL
- A Functional P2X7 Splice Variant with an Alternative Transmembrane Domain 1 Escapes Gene Inactivation in P2X7 Knock-out Mice
- (2009) Annette Nicke et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Clinical Evidence and Potential Neurobiological Underpinnings of Unresolved Symptoms of Depression
- (2009) Madhukar H. Trivedi et al. JOURNAL OF CLINICAL PSYCHIATRY
- Activation of Microglia by Amyloid Requires P2X7 Receptor Expression
- (2009) J. M. Sanz et al. JOURNAL OF IMMUNOLOGY
- The P2X7 Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X7R Pore
- (2009) M. Monif et al. JOURNAL OF NEUROSCIENCE
- Schizophrenia
- (2009) Jim van Os et al. LANCET
- Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients
- (2009) J S Rao et al. MOLECULAR PSYCHIATRY
- Amyloid-β Induces a Caspase-mediated Cleavage of P2X4 to Promote Purinotoxicity
- (2009) R. Varma et al. NEUROMOLECULAR MEDICINE
- Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?
- (2009) Kurt M. Lucin et al. NEURON
- Impaired Interleukin-1β and c-Fos Expression in the Hippocampus Is Associated with a Spatial Memory Deficit in P2X7 Receptor-Deficient Mice
- (2009) Virginie F. Labrousse et al. PLoS One
- Association between depression and the Gln460Arg polymorphism of P2RX7 Gene: A dimensional approach
- (2008) Krisztina Hejjas et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- Higher Risk of Offspring Schizophrenia Following Antenatal Maternal Exposure to Severe Adverse Life Events
- (2008) Ali S. Khashan et al. ARCHIVES OF GENERAL PSYCHIATRY
- Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: Relevance for neuropsychiatric disorders
- (2008) Ana M. Basso et al. BEHAVIOURAL BRAIN RESEARCH
- Cellular localization of P2X7 receptor mRNA in the rat brain
- (2008) Yong Yu et al. BRAIN RESEARCH
- Active Caspase-1 Is a Regulator of Unconventional Protein Secretion
- (2008) Martin Keller et al. CELL
- Activation of P2X7receptors induces CCL3 production in microglial cells through transcription factor NFAT
- (2008) Ayako Kataoka et al. JOURNAL OF NEUROCHEMISTRY
- P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis
- (2008) Anthony J Sharp et al. Journal of Neuroinflammation
- Characterization of N-(Adamantan-1-ylmethyl)-5-[(3R-aminopyrrolidin-1-yl)methyl]-2-chloro-benzamide, a P2X7 Antagonist in Animal Models of Pain and Inflammation
- (2008) D. C. Broom et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Case–control studies show that a non-conservative amino-acid change from a glutamine to arginine in the P2RX7 purinergic receptor protein is associated with both bipolar- and unipolar-affective disorders
- (2008) A McQuillin et al. MOLECULAR PSYCHIATRY
- A CSF biomarker panel for identification of patients with amyotrophic lateral sclerosis
- (2008) R. M. Mitchell et al. NEUROLOGY
- [3H]A-804598 ([3H]2-cyano-1-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine) is a novel, potent, and selective antagonist radioligand for P2X7 receptors
- (2008) Diana L. Donnelly-Roberts et al. NEUROPHARMACOLOGY
- Block of purinergic P2X7 receptor is neuroprotective in an animal model of Alzheimerʼs disease
- (2008) Jae K. Ryu et al. NEUROREPORT
- Increased Level of Extracellular ATP at Tumor Sites: In Vivo Imaging with Plasma Membrane Luciferase
- (2008) Patrizia Pellegatti et al. PLoS One
- P2RX7 Gln460Arg polymorphism is associated with depression among diabetic patients
- (2008) Geza Nagy et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Variation in the purinergic P2RX7 receptor gene and schizophrenia
- (2008) Thomas Hansen et al. SCHIZOPHRENIA RESEARCH
- Expression and function of the P2X7 receptor in rat C6 glioma cells
- (2007) Wei Wei et al. CANCER LETTERS
- Increased P2X7Receptor Expression and Function in Thyroid Papillary Cancer: A New Potential Marker of the Disease?
- (2007) Anna Solini et al. ENDOCRINOLOGY
- Thalidomide inhibition of perturbed vasculature and glial-derived tumor necrosis factor-α in an animal model of inflamed Alzheimer’s disease brain
- (2007) Jae K. Ryu et al. NEUROBIOLOGY OF DISEASE
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