Opposite effects of P2X7 and P2Y2nucleotide receptors on α-secretase-dependent APP processing in Neuro-2a cells

P2X7, NMDA and BDNF receptors converge on GSK3 phosphorylation and cooperate to promote survival in cerebellar granule neurons

(2010) Felipe Ortega et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons

(2010) Peer-Hendrik Kuhn et al.   EMBO JOURNAL

The Purinergic Receptor P2X7 Triggers α-Secretase-dependent Processing of the Amyloid Precursor Protein

(2010) Cécile Delarasse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ca2+/calmodulin-dependent kinase II signalling cascade mediates P2X7 receptor-dependent inhibition of neuritogenesis in neuroblastoma cells

(2009) Rosa Gómez-Villafuertes et al.   FEBS Journal

Interleukin-1β enhances nucleotide-induced and α-secretase-dependent amyloid precursor protein processing in rat primary cortical neurons via up-regulation of the P2Y2receptor

(2009) Qiongman Kong et al.   JOURNAL OF NEUROCHEMISTRY

Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons

(2008) M. Diaz-Hernandez et al.   JOURNAL OF CELL SCIENCE

Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo

(2008) John R. Cirrito et al.   NEURON

Block of purinergic P2X7 receptor is neuroprotective in an animal model of Alzheimerʼs disease

(2008) Jae K. Ryu et al.   NEUROREPORT