P2X7 receptor-induced death of motor neurons by a peroxynitrite/FAS-dependent pathway

Nitration of Hsp90 induces cell death

(2013) M. C. Franco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FasL-triggered death of Jurkat cells requires caspase 8-induced, ATP-dependent cross-talk between fas and the purinergic receptor P2X7

(2012) Adam Aguirre et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Diacetylbis(N(4)-methylthiosemicarbazonato) Copper(II) (CuII(atsm)) Protects against Peroxynitrite-induced Nitrosative Damage and Prolongs Survival in Amyotrophic Lateral Sclerosis Mouse Model

(2011) Cynthia P. W. Soon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cu,Zn-Superoxide Dismutase Increases Toxicity of Mutant and Zinc-deficient Superoxide Dismutase by Enhancing Protein Stability

(2010) Mary Anne Sahawneh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular ATP and the P2X7 receptor in astrocyte-mediated motor neuron death: implications for amyotrophic lateral sclerosis

(2010) Mandi Gandelman et al.   Journal of Neuroinflammation

Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors

(2009) Diana L Donnelly-Roberts et al.   BRITISH JOURNAL OF PHARMACOLOGY

Altered P2X7-receptor level and function in mouse models of Huntington’s disease and therapeutic efficacy of antagonist administration

(2009) Miguel Díaz-Hernández et al.   FASEB JOURNAL

The Proinflammatory Action of Microglial P2 Receptors Is Enhanced in SOD1 Models for Amyotrophic Lateral Sclerosis

(2009) N. D'Ambrosi et al.   JOURNAL OF IMMUNOLOGY

Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury

(2009) W. Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane compartments and purinergic signalling: P2X receptors in neurodegenerative and neuroinflammatory events

(2008) Savina Apolloni et al.   FEBS Journal

Purinergic signalling and disorders of the central nervous system

(2008) Geoffrey Burnstock   NATURE REVIEWS DRUG DISCOVERY

Block of purinergic P2X7 receptor is neuroprotective in an animal model of Alzheimerʼs disease

(2008) Jae K. Ryu et al.   NEUROREPORT

ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1  and IL-18 secretion in an autocrine way

(2008) A. Piccini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA