The Purinergic Receptor P2X7 Triggers α-Secretase-dependent Processing of the Amyloid Precursor Protein

Activated astrocytes: a therapeutic target in Alzheimer’s disease?

(2009) Stacey Fuller et al.   Expert Review of Neurotherapeutics

ADAM10, the Rate-limiting Protease of Regulated Intramembrane Proteolysis of Notch and Other Proteins, Is Processed by ADAMS-9, ADAMS-15, and the γ-Secretase

(2009) Thomas Tousseyn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Pannexin 1 Channel Activates the Inflammasome in Neurons and Astrocytes

(2009) William R. Silverman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A disintegrin and metalloproteinase (ADAM)-mediated ectodomain shedding of ADAM10

(2009) Edward Parkin et al.   JOURNAL OF NEUROCHEMISTRY

Neural progenitor cell death is induced by extracellular ATP via ligation of P2X7 receptor

(2009) Cécile Delarasse et al.   JOURNAL OF NEUROCHEMISTRY

Synaptic NMDA Receptor Activation Stimulates  -Secretase Amyloid Precursor Protein Processing and Inhibits Amyloid-  Production

(2009) S. E. Hoey et al.   JOURNAL OF NEUROSCIENCE

ADAMs 10 and 17 Represent Differentially Regulated Components of a General Shedding Machinery for Membrane Proteins Such as Transforming Growth Factor α, L-Selectin, and Tumor Necrosis Factor α

(2009) Sylvain M. Le Gall et al.   MOLECULAR BIOLOGY OF THE CELL

The Orphan G Protein-Coupled Receptor 3 Modulates Amyloid-Beta Peptide Generation in Neurons

(2009) A. Thathiah et al.   SCIENCE

Signaling at Purinergic P2X Receptors

(2008) Annmarie Surprenant et al.   Annual Review of Physiology

Palmitoylation of the P2X7 receptor, an ATP-gated channel, controls its expression and association with lipid rafts

(2008) P. Gonnord et al.   FASEB JOURNAL

A Novel Sorting Nexin Modulates Endocytic Trafficking and α-Secretase Cleavage of the Amyloid Precursor Protein

(2008) Susanne Schöbel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Amyloid β-Protein Precursor by Phosphorylation and Protein Interactions

(2008) Toshiharu Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid Precursor Protein Trafficking, Processing, and Function

(2008) Gopal Thinakaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of P2X7 receptors causes isoform-specific translocation of protein kinase C in osteoclasts

(2008) S. Armstrong et al.   JOURNAL OF CELL SCIENCE

ATP-gated P2X cation-channels

(2008) Michael F. Jarvis et al.   NEUROPHARMACOLOGY

Selective P2X7 receptor antagonists for chronic inflammation and pain

(2008) William A. Carroll et al.   Purinergic Signalling