Modulation of P2X7 Receptor during Inflammation in Multiple Sclerosis

P2X7 receptor-sensitivity of astrocytes and neurons in the substantia gelatinosa of organotypic spinal cord slices of the mouse depends on the length of the culture period

(2017) Po Gao et al.   NEUROSCIENCE

An updated histological classification system for multiple sclerosis lesions

(2016) Tanja Kuhlmann et al.   ACTA NEUROPATHOLOGICA

MicroRNA-125b regulates microglia activation and motor neuron death in ALS

(2016) C Parisi et al.   CELL DEATH AND DIFFERENTIATION

P2Y12receptor is expressed on human microglia under physiological conditions throughout development and is sensitive to neuroinflammatory diseases

(2016) Alexander Mildner et al.   GLIA

Early P2X7R-related astrogliosis in autoimmune encephalomyelitis

(2016) Tomasz Grygorowicz et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Astrocytes in multiple sclerosis

(2016) Samuel K Ludwin et al.   Multiple Sclerosis Journal

Purinergic contribution to amyotrophic lateral sclerosis

(2016) Cinzia Volonté et al.   NEUROPHARMACOLOGY

Down-regulation of purinergic P2X7 receptor expression and intracellular calcium dysregulation in peripheral blood mononuclear cells of patients with amyotrophic lateral sclerosis

(2016) Jingyu Liu et al.   NEUROSCIENCE LETTERS

Secondary Progression in Multiple Sclerosis: Neuronal Exhaustion or Distinct Pathology?

(2016) Catherine Larochelle et al.   TRENDS IN NEUROSCIENCES

Astrocytes in multiple sclerosis

(2016) Samuel K Ludwin et al.   Multiple Sclerosis Journal

Astrocytes: a central element in neurological diseases

(2015) Milos Pekny et al.   ACTA NEUROPATHOLOGICA

Purinergic signaling in the immune system

(2015) Francesco Di Virgilio et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Inflammatory reaction after traumatic brain injury: therapeutic potential of targeting cell–cell communication by chemokines

(2015) Stefka Gyoneva et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

ATP as a multi-target danger signal in the brain

(2015) Ricardo J. Rodrigues et al.   Frontiers in Neuroscience

The Role of Astrocytes in Multiple Sclerosis Progression

(2015) Jorge Correale et al.   Frontiers in Neurology

Spinal cord pathology is ameliorated by P2X7 antagonism in a SOD1-mutant mouse model of amyotrophic lateral sclerosis

(2014) S. Apolloni et al.   Disease Models & Mechanisms

Differential roles of microglia and monocytes in the inflamed central nervous system

(2014) Ryo Yamasaki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Purinergic signaling mediated by P2X7receptors controls myelination in sciatic nerves

(2014) A. Faroni et al.   JOURNAL OF NEUROSCIENCE RESEARCH

P2Y12Receptor on the Verge of a Neuroinflammatory Breakdown

(2014) Susanna Amadio et al.   MEDIATORS OF INFLAMMATION

Discrepancy in CCL2 and CCR2 expression in white versus grey matter hippocampal lesions of Multiple Sclerosis patients

(2014) Marloes Prins et al.   Acta Neuropathologica Communications

The purinergic P2×7 receptor is expressed on monocytes in Behçet's disease and is modulated by TNF-α

(2013) Monica Castrichini et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The astrocyte in multiple sclerosis revisited

(2013) Celia F. Brosnan et al.   GLIA

Ablation of P2X7 receptor exacerbates gliosis and motoneuron death in the SOD1-G93A mouse model of amyotrophic lateral sclerosis

(2013) S. Apolloni et al.   HUMAN MOLECULAR GENETICS

Immunoregulation through extracellular nucleotides

(2012) L. Vitiello et al.   BLOOD

P2X7 receptor regulation of non-classical secretion from immune effector cells

(2012) George R. Dubyak   CELLULAR MICROBIOLOGY

P2X7 Receptors: Channels, Pores and More

(2012) C. Volonte et al.   CNS & Neurological Disorders-Drug Targets

Transient P2X 7 Receptor Activation Triggers Macrophage Death Independent of Toll-like Receptors 2 and 4, Caspase-1, and Pannexin-1 Proteins

(2012) Peter J. Hanley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monocytes P2X7 purinergic receptor is modulated by glatiramer acetate in multiple sclerosis

(2012) Mariantonietta Caragnano et al.   JOURNAL OF NEUROIMMUNOLOGY

Pathophysiology of astroglial purinergic signalling

(2012) Heike Franke et al.   Purinergic Signalling

Purinergic signalling at the plasma membrane: a multipurpose and multidirectional mode to deal with amyotrophic lateral sclerosis and multiple sclerosis

(2011) Susanna Amadio et al.   JOURNAL OF NEUROCHEMISTRY

Lipid metabolism modulation by the P2X7 receptor in the immune system and during the course of infection: new insights into the old view

(2011) Helio Miranda Costa-Junior et al.   Purinergic Signalling

The human P2X7 receptor and its role in innate immunity

(2011) J. S. Wiley et al.   TISSUE ANTIGENS

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

P2Y12 Receptor Protein in Cortical Gray Matter Lesions in Multiple Sclerosis

(2009) S. Amadio et al.   CEREBRAL CORTEX

P2X7 receptors mediate ischemic damage to oligodendrocytes

(2009) Maria Domercq et al.   GLIA

Receptor webs: Can the chunking theory tell us more about it?

(2008) Cinzia Volonté et al.   BRAIN RESEARCH REVIEWS

Astrocytes in multiple sclerosis: A product of their environment

(2008) A. Nair et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Downregulation of P2X7receptor expression in rat oligodendrocyte precursor cells after hypoxia ischemia

(2008) Li-Yan Wang et al.   GLIA

P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis

(2008) Anthony J Sharp et al.   Journal of Neuroinflammation

P2X7 Receptors in Oligodendrocytes: A Novel Target for Neuroprotection

(2008) Carlos Matute   MOLECULAR NEUROBIOLOGY