International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1–4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions
出版年份 2020 全文链接
标题
International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1–4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions
作者
关键词
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出版物
PHARMACOLOGICAL REVIEWS
Volume 72, Issue 4, Pages 910-968
出版商
American Society for Pharmacology & Experimental Therapeutics (ASPET)
发表日期
2020-09-23
DOI
10.1124/pr.120.019331
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- (2011) Yingji Li et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Targeted Disruption of the Prostaglandin E 2 E-Prostanoid 2 Receptor Exacerbates Vascular Neointimal Formation in Mice
- (2011) Sen Zhu et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Prostaglandins and Inflammation
- (2011) Emanuela Ricciotti et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Altered expression of inflammation-related genes in human carotid atherosclerotic plaques
- (2011) Maria Donata Di Taranto et al. ATHEROSCLEROSIS
- Role of Ca2+-activated K+ channels and Na+,K+-ATPase in prostaglandin E1- and E2-induced inhibition of the adrenergic response in human vas deferens
- (2011) Pascual Medina et al. BIOCHEMICAL PHARMACOLOGY
- Differential reactivity of human mammary artery and saphenous vein to prostaglandin E2: Implication for cardiovascular grafts
- (2011) N Foudi et al. BRITISH JOURNAL OF PHARMACOLOGY
- In vitro and in vivo characterization of PF-04418948, a novel, potent and selective prostaglandin EP2 receptor antagonist
- (2011) KJ af Forselles et al. BRITISH JOURNAL OF PHARMACOLOGY
- Modulation of T cell immune functions by the prostaglandin E2 - cAMP pathway in chronic inflammatory states
- (2011) Kristoffer Watten Brudvik et al. BRITISH JOURNAL OF PHARMACOLOGY
- Prostanoid EP1 receptors mediate up-regulation of the orphan nuclear receptor Nurr1 by cAMP-independent activation of protein kinase A, CREB and NF-κB
- (2011) R Ji et al. BRITISH JOURNAL OF PHARMACOLOGY
- Effect of celecoxib on the antihypertensive effect of losartan in a rat model of renovascular hypertension
- (2011) Vivian Boshra et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- The role of the EP receptors for prostaglandin E2 in skin and skin cancer
- (2011) J. E. Rundhaug et al. CANCER AND METASTASIS REVIEWS
- The Effect of HIV and HPV Coinfection on Cervical COX-2 Expression and Systemic Prostaglandin E2 Levels
- (2011) D. W. Fitzgerald et al. Cancer Prevention Research
- The Effects of Nonsteroidal Anti-Inflammatory Drugs on Blood Pressure in Hypertensive Patients
- (2011) Stanley Snowden et al. Cardiology in Review
- EP4 receptor stimulation down-regulates human eosinophil function
- (2011) Petra Luschnig-Schratl et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Prostanoid Receptors
- (2011) Takako Hirata et al. CHEMICAL REVIEWS
- Microsomal Prostaglandin E 2 Synthase-1 Modulates the Response to Vascular Injury
- (2011) Miao Wang et al. CIRCULATION
- Interaction of eosinophils with endothelial cells is modulated by prostaglandin EP4 receptors
- (2011) Viktoria Konya et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Upregulated Expression of Toll-like Receptor 4 in Peripheral Blood of Ischaemic Stroke Patients Correlates with Cyclooxygenase 2 Expression
- (2011) S. Ferronato et al. EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
- Endothelium-Dependent Contractions in Hypertension
- (2011) Paul M. Vanhoutte HYPERTENSION
- Prostaglandin E2 Induces Matrix Metalloproteinase 9 Expression in Dendritic Cells through Two Independent Signaling Pathways Leading to Activator Protein 1 (AP-1) Activation
- (2011) Jui-Hung Yen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Roles of Prostaglandin EP 1 and 3 Receptors in the Control of Human Myometrial Contractility
- (2011) Shankari Arulkumaran et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Signaling via the prostaglandin E2 receptor EP4 exerts neuronal and vascular protection in a mouse model of cerebral ischemia
- (2011) Xibin Liang et al. JOURNAL OF CLINICAL INVESTIGATION
- Regulation of Immune Responses by Prostaglandin E2
- (2011) P. Kalinski JOURNAL OF IMMUNOLOGY
- Inhibitory effect of prostaglandin I2 on bone marrow kinetics of eosinophils in the guinea pig
- (2011) Eva M. Sturm et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Prostaglandin E2-EP4 signaling suppresses adipocyte differentiation in mouse embryonic fibroblasts via an autocrine mechanism
- (2011) Tomoaki Inazumi et al. JOURNAL OF LIPID RESEARCH
- The cyclooxygenase-2 pathway via the PGE2 EP2 receptor contributes to oligodendrocytes apoptosis in cuprizone-induced demyelination
- (2011) Sara Palumbo et al. JOURNAL OF NEUROCHEMISTRY
- Improvement of cognitive function in Alzheimer’s disease model mice by genetic and pharmacological inhibition of the EP4 receptor
- (2011) Tatsuya Hoshino et al. JOURNAL OF NEUROCHEMISTRY
- Inhibition of prostaglandin E2 EP3 receptors improves stroke injury via anti-inflammatory and anti-apoptotic mechanisms
- (2011) Yuri Ikeda-Matsuo et al. JOURNAL OF NEUROIMMUNOLOGY
- Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility
- (2011) David M Evans et al. NATURE GENETICS
- PGE2 EP1 receptor exacerbated neurotoxicity in a mouse model of cerebral ischemia and Alzheimer's disease
- (2011) Gehua Zhen et al. NEUROBIOLOGY OF AGING
- Abnormal prostaglandin E2 production blocks myogenic differentiation in myotonic dystrophy
- (2011) Daniel Beaulieu et al. NEUROBIOLOGY OF DISEASE
- Characterization of the EP receptor types that mediate longitudinal smooth muscle contraction of human colon, mouse colon and mouse ileum
- (2011) S. E. Fairbrother et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Contribution of peripheral versus central EP1 prostaglandin receptors to inflammatory pain
- (2011) Torbjörn Johansson et al. NEUROSCIENCE LETTERS
- A potential role of chondroitin sulfate on bone in osteoarthritis: inhibition of prostaglandin E2 and matrix metalloproteinases synthesis in interleukin-1β- stimulated osteoblasts
- (2011) E. Pecchi et al. OSTEOARTHRITIS AND CARTILAGE
- International Union of Basic and Clinical Pharmacology. LXXXIII: Classification of Prostanoid Receptors, Updating 15 Years of Progress
- (2011) D. F. Woodward et al. PHARMACOLOGICAL REVIEWS
- EP4 receptor as a new target for bronchodilator therapy
- (2011) J. Buckley et al. THORAX
- COX-2 and Prostaglandin EP3/EP4 Signaling Regulate the Tumor Stromal Proangiogenic Microenvironment via CXCL12-CXCR4 Chemokine Systems
- (2010) Hiroshi Katoh et al. AMERICAN JOURNAL OF PATHOLOGY
- Smooth Muscle Proliferation and Role of the Prostacyclin (IP) Receptor in Idiopathic Pulmonary Arterial Hypertension
- (2010) Emilia Falcetti et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Prostaglandin E2Inhibits Human Lung Fibroblast Chemotaxis through Disparate Actions on Different E-Prostanoid Receptors
- (2010) Ying-Ji Li et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Effects of Prostaglandins E-1, E-2, F-1a and F-2a on Human Sperm Motility
- (2010) A.K. DIDOLKAR et al. ANDROLOGIA
- Prostaglandin EP2 receptor signalling inhibits the expression of matrix metalloproteinase 13 in human osteoarthritic chondrocytes
- (2010) T. Sato et al. ANNALS OF THE RHEUMATIC DISEASES
- The Prostaglandin E 2 Receptor EP4 Is Expressed by Human Platelets and Potently Inhibits Platelet Aggregation and Thrombus Formation
- (2010) Sonia Philipose et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Deletion of EP4 on Bone Marrow–Derived Cells Enhances Inflammation and Angiotensin II–Induced Abdominal Aortic Aneurysm Formation
- (2010) Eva H.C. Tang et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- A novel antagonist of the prostaglandin E2 EP4 receptor inhibits Th1 differentiation and Th17 expansion and is orally active in arthritis models
- (2010) Q Chen et al. BRITISH JOURNAL OF PHARMACOLOGY
- Lack of EP4 receptors on bone marrow-derived cells enhances inflammation in atherosclerotic lesions
- (2010) E. H. C. Tang et al. CARDIOVASCULAR RESEARCH
- Thromboxane A2 induces contraction of human prostate smooth muscle by Rho kinase- and calmodulin-dependent mechanisms
- (2010) Frank Strittmatter et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Role of prostanoid IP and EP receptors in mediating vasorelaxant responses to PGI2 analogues in rat tail artery: Evidence for Gi/o modulation via EP3 receptors
- (2010) Nelson N. Orie et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Endothelium-derived prostaglandin I2 controls the migration of eosinophils
- (2010) Viktoria Konya et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- The Prostaglandin E2Receptor, EP2, Stimulates Keratinocyte Proliferation in Mouse Skin by G Protein-dependent and β-Arrestin1-dependent Signaling Pathways
- (2010) Kyung-Soo Chun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Shear-induced Interleukin-6 Synthesis in Chondrocytes
- (2010) Pu Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prostaglandin I2-IP Signaling Promotes Th1 Differentiation in a Mouse Model of Contact Hypersensitivity
- (2010) S. Nakajima et al. JOURNAL OF IMMUNOLOGY
- Prostaglandin E2 Inhibits Advanced Glycation End Product-Induced Adhesion Molecule Expression on Monocytes, Cytokine Production, and Lymphocyte Proliferation during Human Mixed Lymphocyte Reaction
- (2010) H. K. Takahashi et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Selexipag: A Selective Prostacyclin Receptor Agonist that Does Not Affect Rat Gastric Function
- (2010) K. Morrison et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Prostaglandin E2 Differentially Modulates Human Platelet Function through the Prostanoid EP2 and EP3 Receptors
- (2010) G. Petrucci et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Pharmacological and Functional Characterization of Novel EP and DP Receptor Agonists: DP1 Receptor Mediates Penile Erection in Multiple Species
- (2010) Nadia Brugger et al. Journal of Sexual Medicine
- Cox-2 inhibition attenuates cardiovascular and inflammatory aspects in monosodium glutamate-induced obese rats
- (2010) N.V. Cunha et al. LIFE SCIENCES
- Prostaglandin E2 Promotes Lung Cancer Cell Migration via EP4- Arrestin1-c-Src Signalsome
- (2010) J. I. Kim et al. MOLECULAR CANCER RESEARCH
- Evidence for a Second Receptor for Prostacyclin on Human Airway Epithelial Cells That Mediates Inhibition of CXCL9 and CXCL10 Release
- (2010) S. M. Wilson et al. MOLECULAR PHARMACOLOGY
- EP1 Prostanoid Receptor Coupling to Gi/o Up-Regulates the Expression of Hypoxia-Inducible Factor-1 through Activation of a Phosphoinositide-3 Kinase Signaling Pathway
- (2010) R. Ji et al. MOLECULAR PHARMACOLOGY
- The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis
- (2010) Jérémie Sellam et al. Nature Reviews Rheumatology
- Characterisation of the prostanoid receptor mediating inhibition of smooth muscle contractility in the rat prostate gland
- (2010) Slavko Tokanovic et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Neuroprotective properties of prostaglandin I2 IP receptor in focal cerebral ischemia
- (2010) S. Saleem et al. NEUROSCIENCE
- Differential association between human prostacyclin receptor polymorphisms and the development of venous thrombosis and intimal hyperplasia: a clinical biomarker study
- (2010) Paola Patrignani et al. Pharmacogenetics and Genomics
- The role of prostanoid receptors in mediating the effects of PGE2on human platelet function
- (2010) David Iyú et al. PLATELETS
- Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis
- (2010) Y. Esaki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor
- (2010) J. Jiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective activation of the prostaglandin E2 receptor subtype EP2 or EP4 leads to inhibition of platelet aggregation
- (2010) Koh-ichi Yuhki et al. THROMBOSIS AND HAEMOSTASIS
- PGE2 decreases reactivity of human platelets by activating EP2 and EP4
- (2010) James P. Smith et al. THROMBOSIS RESEARCH
- Prostaglandins in bone: bad cop, good cop?
- (2010) Katherine A. Blackwell et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Antagonists of the EP3Receptor for Prostaglandin E2Are Novel Antiplatelet Agents That Do Not Prolong Bleeding
- (2009) Jasbir Singh et al. ACS Chemical Biology
- Attenuated PGI2 synthesis in obese Zucker rats
- (2009) Benjamin L. Hodnett et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Prostaglandin E2Mediates Cough via the EP3Receptor
- (2009) Sarah A. Maher et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Prostaglandin E2and its cognate EP receptors control human adult articular cartilage homeostasis and are linked to the pathophysiology of osteoarthritis
- (2009) Xin Li et al. ARTHRITIS AND RHEUMATISM
- EP2 receptor activation by prostaglandin E2 leads to induction of HO-1 via PKA and PI3K pathways in C6 cells
- (2009) Min Kyu Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- EP3 prostanoid receptor isoforms utilize distinct mechanisms to regulate ERK 1/2 activation
- (2009) Davelene D. Israel et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation
- (2009) J. Hoggatt et al. BLOOD
- EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures
- (2009) Tomoko Minamizaki et al. BONE
- BGC20-1531, a novel, potent and selective prostanoid EP4receptor antagonist: a putative new treatment for migraine headache
- (2009) KA Maubach et al. BRITISH JOURNAL OF PHARMACOLOGY
- Endothelium modulates vasoconstrictor response to prostaglandin I2 in rat mesenteric resistance arteries: interaction between EP1 and TP receptors
- (2009) FE Xavier et al. BRITISH JOURNAL OF PHARMACOLOGY
- Endothelium-dependent contractions in SHR: a tale of prostanoid TP and IP receptors
- (2009) Michel Félétou et al. BRITISH JOURNAL OF PHARMACOLOGY
- Polymorphisms in fatty acid metabolism-related genes are associated with colorectal cancer risk
- (2009) Birgit Hoeft et al. CARCINOGENESIS
- Activation of prostaglandin E2 EP1 receptor increases arteriolar tone and blood pressure in mice with type 2 diabetes
- (2009) I. Rutkai et al. CARDIOVASCULAR RESEARCH
- Iloprost Prevents Contrast-Induced Nephropathy in Patients With Renal Dysfunction Undergoing Coronary Angiography or Intervention
- (2009) Konstantinos Spargias et al. CIRCULATION
- Prostaglandin E2 enhances Th17 responses via modulation of IL-17 and IFN-γ production by memory CD4+ T cells
- (2009) Giorgio Napolitani et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Regulation of cytokine expression in human plasmacytoid dendritic cells by prostaglandin I2 analogues
- (2009) C-H. Hung et al. EUROPEAN RESPIRATORY JOURNAL
- Prostaglandin EP2 and EP4 receptor agonists in bone formation and bone healing:In vivoandin vitroevidence
- (2009) Simon Graham et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Effect of EP4 agonist (ONO-4819CD) for patients with mild to moderate ulcerative colitis refractory to 5-aminosalicylates: A randomized phase II, placebo-controlled trial
- (2009) Hiroshi Nakase et al. INFLAMMATORY BOWEL DISEASES
- Phosphatase and Tensin Homologue on Chromosome 10 (PTEN) Directs Prostaglandin E2-mediated Fibroblast Responses via Regulation of E Prostanoid 2 Receptor Expression
- (2009) Rommel L. Sagana et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Increased bone mass in adult prostacyclin-deficient mice
- (2009) Chalida Nakalekha et al. JOURNAL OF ENDOCRINOLOGY
- Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling
- (2009) Katia Boniface et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Prostaglandin E 2 Exerts Homeostatic Regulation of Pulmonary Vascular Remodeling in Allergic Airway Inflammation
- (2009) Anders Lundequist et al. JOURNAL OF IMMUNOLOGY
- Elevated cerebrospinal fluid levels of prostaglandin E2 and 15-(S)-hydroxyeicosatetraenoic acid in multiple sclerosis
- (2009) N. Mattsson et al. JOURNAL OF INTERNAL MEDICINE
- Reduced acute brain injury in PGE2 EP3 receptor-deficient mice after cerebral ischemia
- (2009) Sofiyan Saleem et al. JOURNAL OF NEUROIMMUNOLOGY
- Functional Selectivity of Natural and Synthetic Prostaglandin EP4 Receptor Ligands
- (2009) M. Leduc et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
- (2009) Philip L De Jager et al. NATURE GENETICS
- Prostaglandin E2–EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion
- (2009) Chengcan Yao et al. NATURE MEDICINE
- Selective blockade of PGE2 EP1 receptor protects brain against experimental ischemia and excitotoxicity, and hippocampal slice cultures against oxygen-glucose deprivation
- (2009) Abdullah Shafique Ahmad et al. NEUROTOXICITY RESEARCH
- Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis
- (2009) Y. Kihara et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Emerging roles of PGE2 receptors in models of neurological disease
- (2009) Katrin Andreasson PROSTAGLANDINS & OTHER LIPID MEDIATORS
- EP4 agonist alleviates indomethacin-induced gastric lesionsand promotes chronic gastric ulcer healing
- (2009) Guang-Liang Jiang et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Essential role of EP3 subtype in prostaglandin E2-induced adhesion of mouse cultured and peritoneal mast cells to the Arg-Gly-Asp-enriched matrix
- (2008) Mariko Sakanaka et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Increased vascular thromboxane generation impairs dilation of skeletal muscle arterioles of obese Zucker rats with reduced oxygen tension
- (2008) Adam G. Goodwill et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Role of the Prostanoid EP4 Receptor in Iloprost-mediated Vasodilatation in Pulmonary Hypertension
- (2008) Ying-Ju Lai et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- The prostaglandin E2EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis
- (2008) Xibin Liang et al. ANNALS OF NEUROLOGY
- Prostaglandin E2 synergistically with interleukin-23 favors human Th17 expansion
- (2008) C. Chizzolini et al. BLOOD
- Activation of prostaglandin EP receptors by lubiprostone in rat and human stomach and colon
- (2008) A K Bassil et al. BRITISH JOURNAL OF PHARMACOLOGY
- Vasorelaxation induced by prostaglandin E2 in human pulmonary vein: role of the EP4 receptor subtype
- (2008) N Foudi et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cyclooxygenase-2 inhibition increases lipopolysaccharide-induced atherosclerosis in mice
- (2008) J. M. Gitlin et al. CARDIOVASCULAR RESEARCH
- Macrophage EP4 Deficiency Increases Apoptosis and Suppresses Early Atherosclerosis
- (2008) Vladimir R. Babaev et al. Cell Metabolism
- Microsomal Prostaglandin E Synthase-1 Deletion Suppresses Oxidative Stress and Angiotensin II–Induced Abdominal Aortic Aneurysm Formation
- (2008) Miao Wang et al. CIRCULATION
- Acceleration of Cardiovascular Disease by a Dysfunctional Prostacyclin Receptor Mutation
- (2008) Eric Arehart et al. CIRCULATION RESEARCH
- Mutual antagonistic relationship between prostaglandin E2and IFN‐γ: Implications for rheumatoid arthritis
- (2008) Marie‐Claude Mathieu et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Mouse EP3 α, β, and γ Receptor Variants Reduce Tumor Cell Proliferation and Tumorigenesisin Vivo
- (2008) Ines M. Macias-Perez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prostaglandin E2 inhibits BMP signaling and delays chondrocyte maturation
- (2008) Christine A. Clark et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- MF498 [N- -2-(2-methoxyphenyl)acetamide], a Selective E Prostanoid Receptor 4 Antagonist, Relieves Joint Inflammation and Pain in Rodent Models of Rheumatoid and Osteoarthritis
- (2008) P. Clark et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Regulation of smooth muscle contractility by the epithelium in rat vas deferens: role of ATP-induced release of PGE2
- (2008) Ye Chun Ruan et al. JOURNAL OF PHYSIOLOGY-LONDON
- Role of Epac1 in mediating anti-proliferative effects of prostanoid EP2 receptors and cAMP in human lung fibroblasts
- (2008) S. Haag et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Prostaglandin receptor EP2 protects dopaminergic neurons against 6-OHDA-mediated low oxidative stress
- (2008) Emilce Carrasco et al. NEUROSCIENCE LETTERS
- DG-041 inhibits the EP3 prostanoid receptor—A new target for inhibition of platelet function in atherothrombotic disease
- (2008) Stan Heptinstall et al. PLATELETS
- Regulation of the prostaglandin pathway during development of invasive bladder cancer in mice
- (2008) John A. Taylor et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Elevated microsomal prostaglandin-E synthase–1 in Alzheimer’s disease
- (2007) Uzma A. Chaudhry et al. Alzheimers & Dementia
- Physiological Regulation of Prostaglandins in the Kidney
- (2007) Chuan-Ming Hao et al. Annual Review of Physiology
- Effect of femto to nano molar concentrations of prostaglandin analogues on pregnant rat uterine contractility
- (2007) Abdul H. Khan et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Neuroprotection by PGE2 receptor EP1 inhibition involves the PTEN/AKT pathway
- (2007) Ping Zhou et al. NEUROBIOLOGY OF DISEASE
- Effects of gestational age on prostaglandin EP receptor expression and functional involvement during in vitro contraction of the guinea pig uterus
- (2007) K.K. Terry et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- GW627368X ((N-{2-[4-(4,9-diethoxy-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl)phenyl]acetyl} benzene sulphonamide): a novel, potent and selective prostanoid EP4 receptor antagonist
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