The cyclooxygenase-2 pathway via the PGE2 EP2 receptor contributes to oligodendrocytes apoptosis in cuprizone-induced demyelination

Time-dependent changes in the brain arachidonic acid cascade during cuprizone-induced demyelination and remyelination

(2011) S. Palumbo et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Demyelination versus remyelination in progressive multiple sclerosis

(2010) Stephan Bramow et al.   BRAIN

The Prostaglandin E2 E-Prostanoid 4 Receptor Exerts Anti-Inflammatory Effects in Brain Innate Immunity

(2010) J. Shi et al.   JOURNAL OF IMMUNOLOGY

Cyclooxygenase-2 expression in oligodendrocytes increases sensitivity to excitotoxic death

(2010) Noel G Carlson et al.   Journal of Neuroinflammation

CXCR2-positive neutrophils are essential for cuprizone-induced demyelination: relevance to multiple sclerosis

(2010) LiPing Liu et al.   NATURE NEUROSCIENCE

The cuprizone animal model: new insights into an old story

(2009) Markus Kipp et al.   ACTA NEUROPATHOLOGICA

Cuprizone Treatment Induces Distinct Demyelination, Astrocytosis, and Microglia Cell Invasion or Proliferation in the Mouse Cerebellum

(2009) Angela Groebe et al.   CEREBELLUM

Microglial inhibition of neuroprotection by antagonists of the EP1 prostaglandin E2 receptor

(2009) Noel G Carlson et al.   Journal of Neuroinflammation

Prostaglandin E2–EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion

(2009) Chengcan Yao et al.   NATURE MEDICINE

Cerebrospinal fluid biomarkers in multiple sclerosis

(2009) Hayrettin Tumani et al.   NEUROBIOLOGY OF DISEASE

In toxic demyelination oligodendroglial cell death occurs early and is FAS independent

(2009) Amke Hesse et al.   NEUROBIOLOGY OF DISEASE

Lipopolysaccharide-activated microglia induce death of oligodendrocyte progenitor cells and impede their development

(2009) Y. Pang et al.   NEUROSCIENCE

Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis

(2009) Y. Kihara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cuprizone model for demyelination

(2008) Ø. Torkildsen et al.   ACTA NEUROLOGICA SCANDINAVICA

Therapeutic Targets in Prostaglandin E2 Signaling for Neurologic Disease

(2008) P. Cimino et al.   CURRENT MEDICINAL CHEMISTRY

Cuprizone treatment induces demyelination and astrocytosis in the mouse hippocampus

(2008) Akvile Norkute et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Altered GABAergic neurotransmission is associated with increased kainate-induced seizure in prostaglandin-endoperoxide synthase-2 deficient mice

(2007) Christopher D. Toscano et al.   BRAIN RESEARCH BULLETIN