COX2/mPGES1/PGE2pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells

Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination

(2016) Caroline P. Le et al.   Nature Communications

Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity

(2015) Santiago Zelenay et al.   CELL

Anti–PD-1/PD-L1 therapy of human cancer: past, present, and future

(2015) Lieping Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer

(2015) Edward B. Garon et al.   NEW ENGLAND JOURNAL OF MEDICINE

PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma

(2015) Stephen M. Ansell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pembrolizumab versus Ipilimumab in Advanced Melanoma

(2015) Caroline Robert et al.   NEW ENGLAND JOURNAL OF MEDICINE

The myeloid-binding peptide adenoviral vector enables multi-organ vascular endothelial gene targeting

(2014) Zhi Hong Lu et al.   LABORATORY INVESTIGATION

Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance

(2014) Antonina V. Kurtova et al.   NATURE

MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer

(2014) Thomas Powles et al.   NATURE

Infiltration of CD3+ and CD68+ cells in bladder cancer is subtype specific and affects the outcome of patients with muscle-invasive tumors11Grant support: The Swedish Cancer Society, the Swedish research council, the Nilsson Cancer foundation, the BioCARE Strategic Cancer Research program, the Lund Medical Faculty, and FoU Landstinget Kronoberg and Södra Regionvårdnämnden.

(2014) Gottfrid Sjödahl et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Inflammatory Monocytes Recruited to Allergic Skin Acquire an Anti-inflammatory M2 Phenotype via Basophil-Derived Interleukin-4

(2013) Mayumi Egawa et al.   IMMUNITY

A myeloid cell-binding adenovirus efficiently targets gene transfer to the lung and escapes liver tropism

(2012) M O Alberti et al.   GENE THERAPY

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

(2012) Julie R. Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Circulating and tumor-infiltrating myeloid cell subsets in patients with bladder cancer

(2011) Evgeniy Eruslanov et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of Immune Responses by Prostaglandin E2

(2011) P. Kalinski   JOURNAL OF IMMUNOLOGY

Loss of 15-Hydroxyprostaglandin Dehydrogenase Expression Contributes to Bladder Cancer Progression

(2010) Stephanie Tseng-Rogenski et al.   AMERICAN JOURNAL OF PATHOLOGY

Pivotal Advance: Tumor-mediated induction of myeloid-derived suppressor cells and M2-polarized macrophages by altering intracellular PGE2 catabolism in myeloid cells

(2010) Evgeniy Eruslanov et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cyclooxygenase-2 expression on urothelial and inflammatory cells of cystoscopic biopsies and urine cytology as a possible predictive marker for bladder carcinoma

(2009) MONA MOUSSA et al.   APMIS

Enhancing the efficacy of cancer vaccines in urologic oncology: new directions

(2009) Sergei Kusmartsev et al.   Nature Reviews Urology