Antagonism of Neuronal Prostaglandin E2 Receptor Subtype 1 Mitigates Amyloid β Neurotoxicity In Vitro

Amyloid-β Induces Cyclooxygenase-2 and PGE2 Release in Human Astrocytes in NF-κ B Dependent Manner

(2017) Almudena Blanco et al.   JOURNAL OF ALZHEIMERS DISEASE

Apolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's disease

(2011) C Dirk Keene et al.   CURRENT OPINION IN NEUROBIOLOGY

Suppressed microglial E prostanoid receptor 1 signaling selectively reduces tumor necrosis factor alpha and interleukin 6 secretion from toll-like receptor 3 activation

(2011) Xianwu Li et al.   GLIA

Prostaglandin E 2 reduces amyloid β-induced phagocytosis in cultured rat microglia

(2010) Takayuki Nagano et al.   BRAIN RESEARCH

Cyclooxygenase (COX)-1 Activity Precedes the COX-2 Induction in Aβ-Induced Neuroinflammation

(2010) Leila Dargahi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimer's disease

(2010) Thimmappa S. Anekonda et al.   NEUROBIOLOGY OF DISEASE

Elevated Ratio of Urinary Metabolites of Thromboxane and Prostacyclin Is Associated with Adverse Cardiovascular Events in ADAPT

(2010) Thomas J. Montine et al.   PLoS One

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Protection of Hippocampal Neurogenesis from Toll-Like Receptor 4-Dependent Innate Immune Activation by Ablation of Prostaglandin E2 Receptor Subtype EP1 or EP2

(2009) C. Dirk Keene et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulatory role of cytosolic phospholipase A2α in NADPH oxidase activity and in inducible nitric oxide synthase induction by aggregated Aβ1-42in microglia

(2009) I. Szaingurten-Solodkin et al.   GLIA

Altered hippocampal long-term synaptic plasticity in mice deficient in the PGE2 EP2 receptor

(2008) Hongwei Yang et al.   JOURNAL OF NEUROCHEMISTRY

Protective effects of NSAIDs on the development of Alzheimer disease

(2008) Steven C. Vlad et al.   NEUROLOGY

Docosahexaenoic and eicosapentaenoic acids increase neuronal death in response to HuPrP82–146 and Aβ1–42

(2008) Clive Bate et al.   NEUROPHARMACOLOGY

Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: Involvement of endoplasmic reticulum calcium release in oligomer-induced cell death

(2008) R. Resende et al.   NEUROSCIENCE