The Role of microRNAs in Arsenic-Induced Human Diseases: A Review

Arsenic activates STAT3 signaling during the transformation of the human bronchial epithelial cells

(2022) Bandar Almutairy et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Probiotic Characterization of Arsenic-resistant Lactic Acid Bacteria for Possible Application as Arsenic Bioremediation Tool in Fish for Safe Fish Food Production

(2022) Jatindra Nath Bhakta et al.   Probiotics and Antimicrobial Proteins

Candidate master microRNA regulator of arsenic-induced pancreatic beta cell impairment revealed by multi-omics analysis

(2022) Jenna E. Todero et al.   ARCHIVES OF TOXICOLOGY

Research for type 2 diabetes mellitus in endemic arsenism areas in central China: role of low level of arsenic exposure and KEAP1 rs11545829 polymorphism

(2022) Chenlu Fan et al.   ARCHIVES OF TOXICOLOGY

NaAsO2 decreases GSH synthesis by inhibiting GCLC and induces apoptosis through Hela cell mitochondrial damage, mediating the activation of the NF-κB/miR-21 signaling pathway

(2022) Shanshan Ran et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Exposure to a mixture of heavy metals induces cognitive impairment: Genes and microRNAs involved

(2022) Hai Duc Nguyen et al.   TOXICOLOGY

Arsenic Exposure through Dietary Intake and Associated Health Hazards in the Middle East

(2022) Mohammad Idreesh Khan et al.   Nutrients

Extracellular Vesicle-Encapsulated microRNAs as Novel Biomarkers of Lung Health

(2022) Christina M Eckhardt et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The whole transcriptome analysis and the circRNA-lncRNA network construction in arsenic trioxide-treated mice myocardium

(2022) Yanan Jiang et al.   BIOMEDICINE & PHARMACOTHERAPY

Prevalence of type 2 diabetes mellitus in relation to arsenic exposure and metabolism in Mexican women.

(2022) Karla Rangel-Moreno et al.   ENVIRONMENTAL RESEARCH

MicroRNA in Acromegaly: Involvement in the Pathogenesis and in the Response to First-Generation Somatostatin Receptor Ligands

(2022) Daniel G. Henriques et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Extracellular Vesicles in Myeloid Neoplasms

(2022) Christina Karantanou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

hUC-EVs-ATO reduce the severity of acute GVHD by resetting inflammatory macrophages toward the M2 phenotype

(2022) Yan Su et al.   Journal of Hematology & Oncology

The role of hypoxia-associated miRNAs in acquired sensorineural hearing loss

(2022) Sina Safabakhsh et al.   Frontiers in Cellular Neuroscience

The role and mechanism of butyrate in the prevention and treatment of diabetic kidney disease

(2022) Xi Cheng et al.   Frontiers in Microbiology

A Fenton-like cation can improve arsenic trioxide treatment of sclerodermatous chronic Graft-versus-Host Disease in mice

(2022) Charlotte Chêne et al.   Frontiers in Immunology

Advances in molecular characterization of myeloid proliferations associated with Down syndrome

(2022) Jixia Li et al.   Frontiers in Genetics

Small but strong: Pivotal roles and potential applications of snoRNAs in hematopoietic malignancies

(2022) Jian Dong et al.   Frontiers in Oncology

Encapsulation of miRNA and siRNA into Nanomaterials for Cancer Therapeutics

(2022) Mina Zare et al.   Pharmaceutics

MiRNA-148a inhibits cell growth and drug resistance by regulating WNT10a expression in renal cell carcinoma

(2022) Yongsheng Chen et al.   Translational Andrology and Urology

Antagonism of miR-148a attenuates atherosclerosis progression in APOBApobecLdlr+/- mice: A brief report

(2022) Noemi Rotllan et al.   BIOMEDICINE & PHARMACOTHERAPY

Application of nanotechnology to herbal antioxidants as improved phytomedicine: An expanding horizon

(2022) Yachana Mishra et al.   BIOMEDICINE & PHARMACOTHERAPY

Apoptosis evasion via long non-coding RNAs in colorectal cancer

(2022) Muhammad Irfan et al.   Cancer Cell International

The role of microRNAs in neurodegenerative diseases: a review

(2022) Shijie Li et al.   CELL BIOLOGY AND TOXICOLOGY

The current landscape of microRNAs (miRNAs) in bacterial pneumonia: opportunities and challenges

(2022) Fan Zhang et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Evaluation of low-to-moderate arsenic exposure, metabolism and skin lesions in a Turkish rural population exposed through drinking water

(2022) Usama Alshana et al.   CHEMOSPHERE

Mechanism underlying the targeted regulation of the SOD1 3′UTR by the AUF1/Dicer1/miR-155/SOD1 pathway in sodium arsenite-induced liver injury

(2022) Dingnian Bi et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Associations of multiple plasma metals with chronic kidney disease in patients with diabetes

(2022) Ruixin Wang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

As3MT-mediated SAM consumption, which inhibits the methylation of histones and LINE1, is involved in arsenic-induced male reproductive damage

(2022) Lu Wu et al.   ENVIRONMENTAL POLLUTION

BlaDimiR: A Urine-based miRNA Score for Accurate Bladder Cancer Diagnosis and Follow-up

(2022) Cristian Suarez-Cabrera et al.   EUROPEAN UROLOGY

miRNA-10a-5p Targeting the BCL6 Gene Regulates Proliferation, Differentiation and Apoptosis of Chicken Myoblasts

(2022) Genxi Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MicroRNAs in Medicinal Plants

(2022) Mingyang Sun et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Curcumin Sensitises Cancerous Kidney Cells to TRAIL Induced Apoptosis via Let-7C Mediated Deregulation of Cell Cycle Proteins and Cellular Metabolism

(2022) Ismael Obaidi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A national survey of lead and other metal(loids) in residential drinking water in the United States

(2022) Karen D. Bradham et al.   Journal of Exposure Science and Environmental Epidemiology

Disease- and headache-specific microRNA signatures and their predicted mRNA targets in peripheral blood mononuclear cells in migraineurs: role of inflammatory signalling and oxidative stress

(2022) Timea Aczél et al.   JOURNAL OF HEADACHE AND PAIN

Inflammation and Oxidative Stress Role of S100A12 as a Potential Diagnostic and Therapeutic Biomarker in Acute Myocardial Infarction

(2022) Jian Xie et al.   Oxidative Medicine and Cellular Longevity

Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy

(2022) Mehrdad Hashemi et al.   PHARMACOLOGICAL RESEARCH

Arsenic Induces GSK3β-Dependent p-Tau, Neuronal Apoptosis, and Cognitive Impairment via an Interdependent Hippocampal ERα and IL-1/IL-1R1 Mechanism in Female Rats

(2022) Keerti Gupta et al.   TOXICOLOGICAL SCIENCES

Arsenic exposure during porcine oocyte maturation negatively affects embryonic development by triggering oxidative stress-induced mitochondrial dysfunction and apoptosis

(2022) Hyo-Gu Kang et al.   TOXICOLOGY

Groundwater-native Fe(II) oxidation prior to aeration with H2O2 to enhance As(III) removal

(2022) Mrinal Roy et al.   WATER RESEARCH

A Review of the Effect of Preparations from Vegetables of the Asteraceae Family and Cucurbitaceae Family on the Cardiovascular System and Its Diseases

(2022) Agata Rolnik et al.   Nutrients

Novel Insights into miR-944 in Cancer

(2022) Jinze Shen et al.   Cancers

miR-200c-3p, miR-222-5p, and miR-512-3p Constitute a Biomarker Signature of Sorafenib Effectiveness in Advanced Hepatocellular Carcinoma

(2022) Patricia de la Cruz-Ojeda et al.   Cells

Small Nucleolar RNAs and Their Comprehensive Biological Functions in Hepatocellular Carcinoma

(2022) Xiaoyu Liu et al.   Cells

Effects of neuron autophagy induced by arsenic and fluoride on spatial learning and memory in offspring rats

(2022) Qiuyi Zhao et al.   CHEMOSPHERE

Health and economic gain attributable to the introduction of the World Health Organization's drinking water standard on arsenic level in Hungary: A nationwide retrospective study on cancer occurrence and ischemic heart disease mortality

(2022) László Pál et al.   SCIENCE OF THE TOTAL ENVIRONMENT

CircRNA-100284 activates aurora kinase B by inducing methylation of HSP70 via microRNA-217 to promote proliferation of bladder cancer cells

(2021) Zhong-Ming Huang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

miR‐21‐regulated M2 polarization of macrophage is involved in arsenicosis‐induced hepatic fibrosis through the activation of hepatic stellate cells

(2021) Junchao Xue et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Eating microRNAs: pharmacological opportunities for cross‐kingdom regulation and implications in host gene and gut microbiota modulation

(2021) Lorena Pozo‐Acebo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Origins, fate, and actions of methylated trivalent metabolites of inorganic arsenic: progress and prospects

(2021) Miroslav Stýblo et al.   ARCHIVES OF TOXICOLOGY

MicroRNA-mediated regulation of glucose and lipid metabolism

(2021) Pamela Agbu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Connections between endoplasmic reticulum stress-associated unfolded protein response, mitochondria, and autophagy in arsenic-induced carcinogenesis

(2021) Priya Wadgaonkar et al.   SEMINARS IN CANCER BIOLOGY

Dynamic alteration in miRNA and mRNA expression profiles at different stages of chronic arsenic exposure-induced carcinogenesis in a human cell culture model of skin cancer

(2021) Mayukh Banerjee et al.   ARCHIVES OF TOXICOLOGY

MicroRNA-191 blocking the translocation of GLUT4 is involved in arsenite-induced hepatic insulin resistance through inhibiting the IRS1/AKT pathway

(2021) Wenqi Li et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Connection between miRNA Mediation and the Bioactive Effects of Broccoli (Brassica oleracea var. italica): Exogenous miRNA Resistance to Food Processing and GI Digestion

(2021) Luis A. Chapado et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Dysregulation of microRNAs in metal-induced angiogenesis and carcinogenesis

(2021) Lin Wang et al.   SEMINARS IN CANCER BIOLOGY

The ATO/miRNA-885-5p/MTPN axis induces reversal of drug-resistance in cholangiocarcinoma

(2021) Yuting Wang et al.   CELLULAR ONCOLOGY

Changes in metabolomics and lipidomics in brain tissue and their correlations with the gut microbiome after chronic food-derived arsenic exposure in mice

(2021) Chenfei Wang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Environmental arsenic exposure and its contribution to human diseases, toxicity mechanism and management

(2021) Md. Shiblur Rahaman et al.   ENVIRONMENTAL POLLUTION

miR-21 in EVs from pulmonary epithelial cells promotes myofibroblast differentiation via glycolysis in arsenic-induced pulmonary fibrosis

(2021) Peiwen Wang et al.   ENVIRONMENTAL POLLUTION

MicroRNA-129-5p-regulated microglial expression of the surface receptor CD200R1 controls neuroinflammation

(2021) Vikas Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plant and animal small RNA communications between cells and organisms

(2021) Xuemei Chen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Delineating the Effects of Passaging and Exposure in a Longitudinal Study of Arsenic-Induced Squamous Cell Carcinoma in a HaCaT Cell Line Model

(2021) Mayukh Banerjee et al.   TOXICOLOGICAL SCIENCES

The Mechanism of Trivalent Inorganic Arsenic on HIF-1α: a Systematic Review and Meta-analysis

(2020) Jiaqing Liu et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Molecular Mechanisms of Arsenic-Induced Disruption of DNA Repair

(2020) Lok Ming Tam et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Exposure to arsenite and cadmium induces organotoxicity and miRNAs deregulation in male rats

(2020) Farah Mumtaz et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

The expression of microRNAs and exposure to environmental contaminants related to human health: a review

(2020) Maria Rosaria Tumolo et al.   INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH

Global threat of arsenic in groundwater

(2020) Joel Podgorski et al.   SCIENCE

Global solutions to a silent poison

(2020) Yan Zheng   SCIENCE

Transplacental arsenic exposure produced 5-methylcytosine methylation changes and aberrant microRNA expressions in livers of male fetal mice

(2020) Jie Liu et al.   TOXICOLOGY

MicroRNA-124 Reduces Arsenic-induced Endoplasmic Reticulum Stress and Neurotoxicity and is Linked with Neurodevelopment in Children

(2020) Hae-Ryung Park et al.   Scientific Reports

SFPQ is involved in regulating arsenic-induced oxidative stress by interacting with the miRNA-induced silencing complexes

(2020) Ping Guo et al.   ENVIRONMENTAL POLLUTION

Absorbed plant MIR2911 in honeysuckle decoction inhibits SARS-CoV-2 replication and accelerates the negative conversion of infected patients

(2020) Li-Kun Zhou et al.   Cell Discovery

Effect of Gene-Environment Interaction (Arsenic Exposure - PON1 Q192R Polymorphism) on Cardiovascular Disease Biomarkers in Mexican Population

(2020) Ángeles C. Ochoa-Martínez et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

lncRNA OTUD6B-AS1 Exacerbates As2O3-Induced Oxidative Damage in Bladder Cancer via miR-6734-5p-Mediated Functional Inhibition of IDH2

(2020) Yutong Wang et al.   Oxidative Medicine and Cellular Longevity

Identification and Investigation of miRNAs From Gastrodia elata Blume and Their Potential Function

(2020) Chunxin Xia et al.   Frontiers in Pharmacology

Plant miRNAs Reduce Cancer Cell Proliferation by Targeting MALAT1 and NEAT1: A Beneficial Cross-Kingdom Interaction

(2020) Flaviana Marzano et al.   Frontiers in Genetics

MicroRNA-15b in extracellular vesicles from arsenite-treated macrophages promotes the progression of hepatocellular carcinomas by blocking the LATS1-mediated Hippo pathway

(2020) Junjie Li et al.   CANCER LETTERS

LncRNA H19-mediated M2 polarization of macrophages promotes myofibroblast differentiation in pulmonary fibrosis induced by arsenic exposure

(2020) Tian Xiao et al.   ENVIRONMENTAL POLLUTION

Arsenic-induced changes in miRNA expression in cancer and other diseases

(2020) Ana P. Ferragut Cardoso et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

microRNA-21, via the HIF-1α/VEGF signaling pathway, is involved in arsenite-induced hepatic fibrosis through aberrant cross-talk of hepatocytes and hepatic stellate cells

(2020) Jing Sun et al.   CHEMOSPHERE

Skp2 Expression Is Inhibited by Arsenic Trioxide through the Upregulation of miRNA-330-5p in Pancreatic Cancer Cells

(2019) Jiankun Gao et al.   Molecular Therapy-Oncolytics

Strategies to inhibit arsenic trioxide-induced cardiotoxicity in acute promyelocytic leukemia

(2019) Habib Haybar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Circulating miRNA-126, -145 and -155 levels in Mexican women exposed to inorganic arsenic via drinking water

(2019) Tania Ruíz-Vera et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Abnormal Expression of DICER1 Leads to Dysregulation of Inflammatory Effectors in Human Synoviocytes

(2019) Congshan Jiang et al.   MEDIATORS OF INFLAMMATION

Plant MIR156 Regulates Intestinal Growth in Mammals by Targeting the Wnt/β-catenin Pathway

(2019) Meng Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Plant-derived RNAi therapeutics: A strategic inhibitor of HBsAg

(2019) Shuo Zhang et al.   BIOMATERIALS

MicroRNAs play an important role in contributing to arsenic susceptibility in the chronically exposed individuals of West Bengal, India

(2019) Nilanjana Banerjee et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Genome-wide CRISPR screen identifies suppressors of endoplasmic reticulum stress-induced apoptosis

(2019) Ronald A. Panganiban et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arsenic-Induced Carcinogenesis and Immune Dysregulation

(2019) Hsin-Wei Huang et al.   International Journal of Environmental Research and Public Health

Differential expression of microRNAs in Alzheimer's disease brain, blood, and cerebrospinal fluid

(2019) Petros Takousis et al.   Alzheimers & Dementia

miR-191 is involved in renal dysfunction in arsenic-exposed populations by regulating inflammatory response caused by arsenic from burning arsenic-contaminated coal

(2019) Y Xu et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Association and risk of five miRNAs with arsenic-induced multiorgan damage

(2019) Qibing Zeng et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Overexpression of hsa-miR-186 induces chromosomal instability in arsenic-exposed human keratinocytes

(2019) Jiguo Wu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Health risk assessments of arsenic and toxic heavy metal exposure in drinking water in northeast Iran

(2019) Hosein Alidadi et al.   Environmental Health and Preventive Medicine

Exosomal MALAT1 derived from hepatic cells is involved in the activation of hepatic stellate cells via miRNA-26b in fibrosis induced by arsenite

(2019) Xiangyu Dai et al.   TOXICOLOGY LETTERS

Plant MIR167e-5p Inhibits Enterocyte Proliferation by Targeting β-Catenin

(2019) Meng Li et al.   Cells

piR‐39980 promotes cell proliferation, migration and invasion, and inhibits apoptosis via repression of SERPINB1 in human osteosarcoma

(2019) Basudeb Das et al.   BIOLOGY OF THE CELL

De-methylation of miR-148a by arsenic trioxide enhances sensitivity to chemotherapy via inhibiting the NF-κB pathway and CSC like properties

(2019) Yuting Wang et al.   EXPERIMENTAL CELL RESEARCH

Targeting the miR-122/PKM2 autophagy axis relieves arsenic stress

(2019) Yu Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

PBMC gene expression profiles of female Bangladeshi adults chronically exposed to arsenic-contaminated drinking water

(2019) Qiao Yi Chen et al.   ENVIRONMENTAL POLLUTION

Environmental Stressors and Their Impact on Health and Disease with Focus on Oxidative Stress

(2018) Thomas Münzel et al.   ANTIOXIDANTS & REDOX SIGNALING

Study on the inhibition of Mfn1 by plant-derived miR5338 mediating the treatment of BPH with rape bee pollen

(2018) Xuan Chen et al.   BMC Complementary and Alternative Medicine

The Long Intergenic Noncoding RNA 00707 Promotes Lung Adenocarcinoma Cell Proliferation and Migration by Regulating Cdc42

(2018) Tianshi Ma et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Extracellular Vesicles in Lung Disease

(2018) Hiroshi Kubo   CHEST

The Pax protein Eyegone (Eyg) interacts with the pi-RNA component Aubergine (Aub) and controls egg chamber development in Drosophila

(2018) David Blom-Dahl et al.   DEVELOPMENTAL BIOLOGY

Role of microRNAs in senescence and its contribution to peripheral neuropathy in the arsenic exposed population of West Bengal, India

(2018) Debmita Chatterjee et al.   ENVIRONMENTAL POLLUTION

The PKCδ-Nrf2-ARE signalling pathway may be involved in oxidative stress in arsenic-induced liver damage in rats

(2018) Yong Hu et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Investigating piwi-interacting RNA regulome in human neuroblastoma

(2018) Jyoti Roy et al.   GENES CHROMOSOMES & CANCER

The potential atheroprotective role of plant MIR156a as a repressor of monocyte recruitment on inflamed human endothelial cells

(2018) Dongxia Hou et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Growth Factors and Neuroglobin in Astrocyte Protection Against Neurodegeneration and Oxidative Stress

(2018) Ricardo Cabezas et al.   MOLECULAR NEUROBIOLOGY

Inhibition of miR-219 Alleviates Arsenic-Induced Learning and Memory Impairments and Synaptic Damage Through Up-regulating CaMKII in the Hippocampus

(2018) Dunjia Wang et al.   NEUROCHEMICAL RESEARCH

Genome-wide profiling of the PIWI-interacting RNA-mRNA regulatory networks in epithelial ovarian cancers

(2018) Garima Singh et al.   PLoS One

Arsenic-Induced Carcinogenesis: The Impact of miRNA Dysregulation

(2018) Ana P Ferragut Cardoso et al.   TOXICOLOGICAL SCIENCES

Differentially Expressed mRNA Targets of Differentially Expressed miRNAs Predict Changes in the TP53 Axis and Carcinogenesis-Related Pathways in Human Keratinocytes Chronically Exposed to Arsenic

(2018) Laila Al-Eryani et al.   TOXICOLOGICAL SCIENCES

miR-149 Negative Regulation of mafA Is Involved in the Arsenite-Induced Dysfunction of Insulin Synthesis and Secretion in Pancreatic Beta Cells

(2018) Qian Sun et al.   TOXICOLOGICAL SCIENCES

MicroRNA-191, regulated by HIF-2α, is involved in EMT and acquisition of a stem cell-like phenotype in arsenite-transformed human liver epithelial cells

(2018) Chao Chen et al.   TOXICOLOGY IN VITRO

miR-145 via targeting ERCC2 is involved in arsenite-induced DNA damage in human hepatic cells

(2018) Shaofeng Wei et al.   TOXICOLOGY LETTERS

Exosomal circRNA_100284 from arsenite-transformed cells, via microRNA-217 regulation of EZH2, is involved in the malignant transformation of human hepatic cells by accelerating the cell cycle and promoting cell proliferation

(2018) Xiangyu Dai et al.   Cell Death & Disease

Journey of siRNA: Clinical Developments and Targeted Delivery

(2018) Rahul R. Nikam et al.   Nucleic Acid Therapeutics

RNA-binding protein AUF1 suppresses miR-122 biogenesis by down-regulating Dicer1 in hepatocellular carcinoma

(2018) Xia Wu et al.   Oncotarget

Circ008913, via miR-889 regulation of DAB2IP/ZEB1, is involved in the arsenite-induced acquisition of CSC-like properties by human keratinocytes in carcinogenesis

(2018) Tian Xiao et al.   Metallomics

miRNA-182-5p, via HIF2α, contributes to arsenic carcinogenesis: Evidence from human renal epithelial cells

(2018) Xin Fang et al.   Metallomics

miRNA expression profiles of premalignant and malignant arsenic-induced skin lesions

(2018) Laila Al-Eryani et al.   PLoS One

Olea europaea small RNA with functional homology to human miR34a in cross-kingdom interaction of anti-tumoral response

(2018) Antonella Minutolo et al.   Scientific Reports

M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon Cancer

(2018) Jingqin Lan et al.   CANCER RESEARCH

Circulating miRNAs Associated with Arsenic Exposure

(2018) Rowan Beck et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Tumor suppressive activity of PIWI-interacting RNA in human fibrosarcoma mediated through repression of RRM2

(2018) Basudeb Das et al.   MOLECULAR CARCINOGENESIS

Food-Derived Xeno-microRNAs: Influence of Diet and Detectability in Gastrointestinal Tract-Proof-of-Principle Study

(2018) Jastin Link et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Role of the CD200-CD200R Axis During Homeostasis and Neuroinflammation

(2018) Gemma Manich et al.   NEUROSCIENCE

MicroRNAs from plants to animals, do they define a new messenger for communication?

(2018) Zhiqing Li et al.   Nutrition & Metabolism

Evaluation of epigenetic alterations (mir-126 and mir-155 expression levels) in Mexican children exposed to inorganic arsenic via drinking water

(2017) Mónica S. Pérez-Vázquez et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

State of the art in microRNA as diagnostic and therapeutic biomarkers in chronic lymphocytic leukemia

(2017) Hamed Mirzaei et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Gene networks in neurodegenerative disorders

(2017) Daniela Recabarren et al.   LIFE SCIENCES

Small RNA sequencing revealed dysregulated piRNAs in Alzheimer's disease and their probable role in pathogenesis

(2017) Jyoti Roy et al.   Molecular BioSystems

NF-κB-regulated miR-155, via repression of QKI, contributes to the acquisition of CSC-like phenotype during the neoplastic transformation of hepatic cells induced by arsenite

(2017) Chao Chen et al.   MOLECULAR CARCINOGENESIS

CircLRP6 Regulation of ZEB1 via miR-455 Is Involved in the Epithelial-Mesenchymal Transition During Arsenite-Induced Malignant Transformation of Human Keratinocytes

(2017) Junchao Xue et al.   TOXICOLOGICAL SCIENCES

Increased microRNA 21 expression contributes to arsenic induced skin lesions, skin cancers and respiratory distress in chronically exposed individuals

(2017) Nilanjana Banerjee et al.   TOXICOLOGY

Genetic and epigenetic mechanisms underlying arsenic-associated diabetes mellitus: a perspective of the current evidence

(2017) Elizabeth M. Martin et al.   Epigenomics

Integration of microRNAome, proteomics and metabolomics to analyze arsenic-induced malignant cell transformation

(2017) Youyou Zhou et al.   Oncotarget

Dietary miR-451 protects erythroid cells from oxidative stress via increasing the activity of Foxo3 pathway

(2017) Wanchen Wang et al.   Oncotarget

Metabolism, toxicity and anticancer activities of arsenic compounds

(2017) Islam Khairul et al.   Oncotarget

Circulating miRNAs and their target genes associated with arsenism caused by coal-burning

(2017) Baofei Sun et al.   Toxicology Research

Alterations of miRNAs and Their Potential Roles in Arsenite-Induced Transformation of Human Bronchial Epithelial Cells

(2017) Shiyan Gu et al.   Genes

Idiopathic pulmonary fibrosis

(2017) Fernando J. Martinez et al.   Nature Reviews Disease Primers

Detection of dietetically absorbed maize-derived microRNAs in pigs

(2017) Yi Luo et al.   Scientific Reports

Arsenic trioxide suppresses cell growth and migration via inhibition of miR-27a in breast cancer cells

(2016) Shunhua Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cross-kingdom inhibition of breast cancer growth by plant miR159

(2016) Andrew R Chin et al.   CELL RESEARCH

HNF-4α regulated miR-122 contributes to development of gluconeogenesis and lipid metabolism disorders in Type 2 diabetic mice and in palmitate-treated HepG2 cells

(2016) Shengnan Wei et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Genome-wide identification and functional annotation of miRNAs in anti-inflammatory plant and their cross-kingdom regulation in Homo sapiens

(2016) Ankita Sharma et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Comparative cytotoxicity of fourteen trivalent and pentavalent arsenic species determined using real-time cell sensing

(2016) Birget Moe et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

The role of miR-126 in embryonic angiogenesis, adult vascular homeostasis, and vascular repair and its alterations in atherosclerotic disease

(2016) Dimitry A. Chistiakov et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Endogenous microRNA sponges: evidence and controversy

(2016) Daniel W. Thomson et al.   NATURE REVIEWS GENETICS

Arsenic-induced anti-angiogenesis via miR-425-5p-regulated CCM3

(2016) Yanfang Gao et al.   TOXICOLOGY LETTERS

MicroRNA-21 activation of ERK signaling via PTEN is involved in arsenite-induced autophagy in human hepatic L-02 cells

(2016) Xinlu Liu et al.   TOXICOLOGY LETTERS

HIF-2α, acting via miR-191, is involved in angiogenesis and metastasis of arsenite-transformed HBE cells

(2016) Wenchao Xu et al.   Toxicology Research

A possible new mechanism and drug intervention for kidney damage due to arsenic poisoning in rats

(2016) Yu-yan Xu et al.   Toxicology Research

Plant microRNAs as novel immunomodulatory agents

(2016) Duccio Cavalieri et al.   Scientific Reports

Proteomic Characterization of the World Trade Center dust-activated mdig and c-myc signaling circuit linked to multiple myeloma

(2016) Kai Wu et al.   Scientific Reports

Oncogenic transformation of human lung bronchial epithelial cells induced by arsenic involves ROS-dependent activation of STAT3-miR-21-PDCD4 mechanism

(2016) Poyil Pratheeshkumar et al.   Scientific Reports

Arsenic trioxide Alters the MicroRNA Expression Profile of U87 glioblastoma

(2015) Fatemeh Shidfar et al.   Anti-Cancer Agents in Medicinal Chemistry

Involvement of Epigenetics and EMT-Related miRNA in Arsenic-Induced Neoplastic Transformation and Their Potential Clinical Use

(2015) C. Michailidi et al.   Cancer Prevention Research

Uptake and Function Studies of Maternal Milk-derived MicroRNAs

(2015) Alexandra C. Title et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-specific regulatory mechanisms in atherosclerosis

(2015) Maliheh Nazari-Jahantigh et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

microRNA (miRNA)-Mediated Pathogenetic Signaling in Alzheimer’s Disease (AD)

(2015) James M. Hill et al.   NEUROCHEMICAL RESEARCH

VEGFA Expression Is Inhibited by Arsenic Trioxide in HUVECs through the Upregulation of Ets-2 and miRNA-126

(2015) Hong-yan Ge et al.   PLoS One

Epidemiology of chronic disease related to arsenic in Argentina: A systematic review

(2015) Ariel Esteban Bardach et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Arsenic responsive microRNAs in vivo and their potential involvement in arsenic-induced oxidative stress

(2015) Xuefeng Ren et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

MicroRNA-21, up-regulated by arsenite, directs the epithelial–mesenchymal transition and enhances the invasive potential of transformed human bronchial epithelial cells by targeting PDCD4

(2015) Fei Luo et al.   TOXICOLOGY LETTERS

MicroRNA-451 regulates stemness of side population cells via PI3K/Akt/mTOR signaling pathway in multiple myeloma

(2015) Juan Du et al.   Oncotarget

Small non-coding RNAs transfer through mammalian placenta and directly regulate fetal gene expression

(2015) Jing Li et al.   Protein & Cell

Arsenic Trioxide Inhibits CXCR4-Mediated Metastasis by Interfering miR-520h/PP2A/NF-κB Signaling in Cervical Cancer

(2014) Yi-Wen Chang et al.   ANNALS OF SURGICAL ONCOLOGY

Genotoxic and epigenetic mechanisms in arsenic carcinogenicity

(2014) Elisa Bustaffa et al.   ARCHIVES OF TOXICOLOGY

Exosomal miR-21 derived from arsenite-transformed human bronchial epithelial cells promotes cell proliferation associated with arsenite carcinogenesis

(2014) Yuan Xu et al.   ARCHIVES OF TOXICOLOGY

Up-regulation of miR-21 and miR-23a Contributes to As2O3-induced hERG Channel Deficiency

(2014) Xin Zhao et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Carcinogenic metalloid arsenic induces expression of mdig oncogene through JNK and STAT3 activation

(2014) Jiaying Sun et al.   CANCER LETTERS

Inhibition of transforming growth factor beta/SMAD signal by MiR-155 is involved in arsenic trioxide-induced anti-angiogenesis in prostate cancer

(2014) Hui Ji et al.   CANCER SCIENCE

Uptake and toxicity of arsenite and arsenate in cultured brain astrocytes

(2014) Yvonne Koehler et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

The RNA World: molecular cooperation at the origins of life

(2014) Paul G. Higgs et al.   NATURE REVIEWS GENETICS

Upregulation of miR-21 in Cisplatin Resistant Ovarian Cancer via JNK-1/c-Jun Pathway

(2014) Ileabett M. Echevarría-Vargas et al.   PLoS One

Aberrant microRNA Expression Likely Controls RAS Oncogene Activation During Malignant Transformation of Human Prostate Epithelial and Stem Cells by Arsenic

(2014) Ntube N. O. Ngalame et al.   TOXICOLOGICAL SCIENCES

Inhibition of TGF-β/SMAD3/NF-κB signaling by microRNA-491 is involved in arsenic trioxide-induced anti-angiogenesis in hepatocellular carcinoma cells

(2014) Fei Jiang et al.   TOXICOLOGY LETTERS

The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-κB

(2014) Rongrong Jiang et al.   TOXICOLOGY LETTERS

Assessing the survival of exogenous plant microRNA in mice

(2014) GaoFeng Liang et al.   Food Science & Nutrition

MicroRNAs Contribute to Promyelocyte Apoptosis in As2O3-Treated APL Cells

(2013) Haihai Liang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Prenatal arsenic exposure and the epigenome: Altered microRNAs associated with innate and adaptive immune signaling in newborn cord blood

(2013) Julia E. Rager et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Delivery materials for siRNA therapeutics

(2013) Rosemary Kanasty et al.   NATURE MATERIALS

Arsenic exposure triggers a shift in microRNA expression

(2013) Elena Sturchio et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Arsenite evokes IL-6 secretion, autocrine regulation of STAT3 signaling, and miR-21 expression, processes involved in the EMT and malignant transformation of human bronchial epithelial cells

(2013) Fei Luo et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Angiogenesis, mediated by miR-21, is involved arsenite-induced carcinogenesis

(2013) Yue Zhao et al.   TOXICOLOGY LETTERS

Altered expression profiles of microRNAs upon arsenic exposure of human umbilical vein endothelial cells

(2012) Xinna Li et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Regulation of miRNA-21 by reactive oxygen species-activated ERK/NF-κB in arsenite-induced cell transformation

(2012) Min Ling et al.   FREE RADICAL BIOLOGY AND MEDICINE

Upregulation of microRNA-1 and microRNA-133 contributes to arsenic-induced cardiac electrical remodeling

(2012) Hongli Shan et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Prenatal Arsenic Exposure Alters Gene Expression in the Adult Liver to a Proinflammatory State Contributing to Accelerated Atherosclerosis

(2012) J. Christopher States et al.   PLoS One

The association between total urinary arsenic concentration and renal dysfunction in a community-based population from central Taiwan

(2011) Jein-Wen Chen et al.   CHEMOSPHERE

MicroRNA-181b and microRNA-9 mediate arsenic-induced angiogenesis via NRP1

(2011) Yi Cui et al.   JOURNAL OF CELLULAR PHYSIOLOGY

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling

(2011) A. Davalos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-190-Mediated Downregulation of PHLPP Contributes to Arsenic-Induced Akt Activation and Carcinogenesis

(2011) Kevin Beezhold et al.   TOXICOLOGICAL SCIENCES

Reversal and Prevention of Arsenic-Induced Human Bronchial Epithelial Cell Malignant Transformation by microRNA-200b

(2011) Zhishan Wang et al.   TOXICOLOGICAL SCIENCES

The Arsenic Exposure Hypothesis for Alzheimer Disease

(2010) Gordon Gong et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Anti-miR-21 oligonucleotide sensitizes leukemic K562 cells to arsenic trioxide by inducing apoptosis

(2010) Yumin Li et al.   CANCER SCIENCE

Regulation of Human Cardiac Ion Channel Genes by MicroRNAs: Theoretical Perspective and Pathophysiological Implications

(2010) Xiaobin Luo et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

miRNA-21 regulates arsenic-induced anti-leukemia activity in myelogenous cell lines

(2010) Jingyi Gu et al.   MEDICAL ONCOLOGY

The widespread regulation of microRNA biogenesis, function and decay

(2010) Jacek Krol et al.   NATURE REVIEWS GENETICS

Arsenic for the fool: An exponential connection

(2010) Sergio U. Dani   SCIENCE OF THE TOTAL ENVIRONMENT

A Brief Review on the Mechanisms of miRNA Regulation

(2010) Yimei Cai et al.   GENOMICS PROTEOMICS & BIOINFORMATICS