HIF-2α, acting via miR-191, is involved in angiogenesis and metastasis of arsenite-transformed HBE cells

A genetic variant of MDM4 influences regulation by multiple microRNAs in prostate cancer

(2015) S. Stegeman et al.   ENDOCRINE-RELATED CANCER

MiR-199a-5p is negatively associated with malignancies and regulates glycolysis and lactate production by targeting hexokinase 2 in liver cancer

(2015) Weijie Guo et al.   HEPATOLOGY

Broad targeting of angiogenesis for cancer prevention and therapy

(2015) Zongwei Wang et al.   SEMINARS IN CANCER BIOLOGY

Seeing through VEGF: innate and adaptive immunity in pathological angiogenesis in the eye

(2015) Abdoulaye Sene et al.   TRENDS IN MOLECULAR MEDICINE

The chemokine receptor CXCR7 is a critical regulator for the tumorigenesis and development of papillary thyroid carcinoma by inducing angiogenesis in vitro and in vivo

(2015) Hengwei Zhang et al.   TUMOR BIOLOGY

The role of hypoxia-inducible factor-2 in digestive system cancers

(2015) J Zhao et al.   Cell Death & Disease

UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α

(2015) Yoko Goto et al.   Nature Communications

Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis

(2015) Xiao Xiao et al.   Oncotarget

Correlation between vascular endothelial growth factor expression and presence of lymph node metastasis in advanced squamous cell carcinoma of the larynx

(2015) Rodrigo Gonzalez Bonhin et al.   Brazilian Journal of Otorhinolaryngology

WT1 regulates angiogenesis in Ewing Sarcoma

(2015) Varalakshimi Katuri et al.   Oncotarget

Hypomethylation of the hsa-miR-191 Locus Causes High Expression of hsa-miR-191 and Promotes the Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma

(2015) Yinghua He et al.   NEOPLASIA

Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1

(2014) T. Umezu et al.   BLOOD

ALK-Dependent Control of Hypoxia-Inducible Factors Mediates Tumor Growth and Metastasis

(2014) C. Martinengo et al.   CANCER RESEARCH

Upregulation of HIF-2α induced by sorafenib contributes to the resistance by activating the TGF-α/EGFR pathway in hepatocellular carcinoma cells

(2014) Dali Zhao et al.   CELLULAR SIGNALLING

A feedback regulatory loop between HIF-1α and miR-21 in response to hypoxia in cardiomyocytes

(2014) Yang Liu et al.   FEBS LETTERS

Role of miR-191/425 Cluster in Tumorigenesis and Diagnosis of Gastric Cancer

(2014) Wei-Zhao Peng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hypoxia-induced miR-210 in epithelial ovarian cancer enhances cancer cell viability via promoting proliferation and inhibiting apoptosis

(2014) LI’AN LI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

MiRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features

(2014) Bin Wang et al.   IUBMB LIFE

MicroRNA-191, by promoting the EMT and increasing CSC-like properties, is involved in neoplastic and metastatic properties of transformed human bronchial epithelial cells

(2014) Wenchao Xu et al.   MOLECULAR CARCINOGENESIS

MicroRNA-382 induced by HIF-1α is an angiogenic miR targeting the tumor suppressor phosphatase and tensin homolog

(2014) Jin-Kyung Seok et al.   NUCLEIC ACIDS RESEARCH

c-Myc-mediated repression of miR-15-16 in hypoxia is induced by increased HIF-2α and promotes tumor angiogenesis and metastasis by upregulating FGF2

(2014) G Xue et al.   ONCOGENE

MiR-338-3p Inhibits Hepatocarcinoma Cells and Sensitizes These Cells to Sorafenib by Targeting Hypoxia-Induced Factor 1α

(2014) Haitao Xu et al.   PLoS One

The clinical significance and regulation mechanism of hypoxia-inducible factor-1 and miR-191 expression in pancreatic cancer

(2014) Zhenguo Song et al.   TUMOR BIOLOGY

A systematic review of matrix metalloproteinase 9 as a biomarker of survival in patients with osteosarcoma

(2014) Hui Li et al.   TUMOR BIOLOGY

The Wilms’ tumour suppressor Wt1 is a major regulator of tumour angiogenesis and progression

(2014) Kay-Dietrich Wagner et al.   Nature Communications

miR-191: an emerging player in disease biology

(2014) Neha Nagpal et al.   Frontiers in Genetics

HIF expression and the role of hypoxic microenvironments within primary tumours as protective sites driving cancer stem cell renewal and metastatic progression

(2013) B. Philip et al.   CARCINOGENESIS

Angiogenesis, mediated by miR-21, is involved arsenite-induced carcinogenesis

(2013) Yue Zhao et al.   TOXICOLOGY LETTERS

Blockade of p53 by HIF-2α, but not HIF-1α, is involved in arsenite-induced malignant transformation of human bronchial epithelial cells

(2012) Yuan Xu et al.   ARCHIVES OF TOXICOLOGY

MicroRNA profiling of hepatocarcinogenesis identifies C19MC cluster as a novel prognostic biomarker in hepatocellular carcinoma

(2012) Claudia Augello et al.   LIVER INTERNATIONAL

MicroRNA-145 inhibits the growth, invasion, metastasis and angiogenesis of neuroblastoma cells through targeting hypoxia-inducible factor 2 alpha

(2012) H Zhang et al.   ONCOGENE

EMT and Stem Cell-Like Properties Associated with HIF-2α Are Involved in Arsenite-Induced Transformation of Human Bronchial Epithelial Cells

(2012) Yuan Xu et al.   PLoS One

Molecular mechanisms mediating metastasis of hypoxic breast cancer cells

(2012) Gregg L. Semenza   TRENDS IN MOLECULAR MEDICINE

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The Art of MicroRNA Research

(2011) Eva van Rooij   CIRCULATION RESEARCH

microRNA: A Master Regulator of Cellular Processes for Bioengineering Systems

(2010) Wei Sun et al.   Annual Review of Biomedical Engineering

MicroRNA-210: A unique and pleiotropic hypoxamir

(2010) Stephen Y. Chan et al.   CELL CYCLE

Roles of hypoxia-inducible factor-1α (HIF-1α) versus HIF-2α in the survival of hepatocellular tumor spheroids

(2010) Heidi Menrad et al.   HEPATOLOGY

HIF-1 and HIF-2 transcription factors — Similar but not identical

(2010) Agnieszka Loboda et al.   MOLECULES AND CELLS

Overexpression of MicroRNA miR-30a or miR-191 in A549 Lung Cancer or BEAS-2B Normal Lung Cell Lines Does Not Alter Phenotype

(2010) Santosh Kumar Patnaik et al.   PLoS One

Arsenic-induced malignant transformation of human keratinocytes: Involvement of Nrf2

(2008) Jingbo Pi et al.   FREE RADICAL BIOLOGY AND MEDICINE