microRNA-21, via the HIF-1α/VEGF signaling pathway, is involved in arsenite-induced hepatic fibrosis through aberrant cross-talk of hepatocytes and hepatic stellate cells

Arsenic Toxicity: Molecular Targets and Therapeutic Agents

(2020) Valeria M. Nurchi et al.   Biomolecules

The innate immune cells in cirrhosis

(2020) Christine Bernsmeier et al.   JOURNAL OF HEPATOLOGY

Role of microRNA in the pathogenesis of systemic sclerosis tissue fibrosis and vasculopathy

(2019) Tyler W. Henry et al.   AUTOIMMUNITY REVIEWS

Exosomal MALAT1 derived from hepatic cells is involved in the activation of hepatic stellate cells via miRNA-26b in fibrosis induced by arsenite

(2019) Xiangyu Dai et al.   TOXICOLOGY LETTERS

Gant61 ameliorates CCl4-induced liver fibrosis by inhibition of Hedgehog signaling activity

(2019) Shen Jiayuan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Hedgehog signaling pathway regulates hexavalent chromium-induced liver fibrosis by activation of hepatic stellate cells

(2019) Junyan Yan et al.   TOXICOLOGY LETTERS

Hepatocyte-specific Nrf2 deficiency mitigates high-fat diet-induced hepatic steatosis: Involvement of reduced PPARγ expression

(2019) Lu Li et al.   Redox Biology

Knockout of microRNA-21 attenuates alcoholic hepatitis through VHL/NF-κB signaling pathway in hepatic stellate cells

(2018) Nan Wu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Environmental arsenic exposure: From genetic susceptibility to pathogenesis

(2018) Brenda C. Minatel et al.   ENVIRONMENT INTERNATIONAL

Impact of prenatal arsenic exposure on chronic adult diseases

(2018) Jamie L. Young et al.   Systems Biology in Reproductive Medicine

The Association of Arsenic Metabolism with Cancer, Cardiovascular Disease, and Diabetes: A Systematic Review of the Epidemiological Evidence

(2017) Chin-Chi Kuo et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The roles of microRNA families in hepatic fibrosis

(2017) Xue-Ping Jiang et al.   Cell and Bioscience

Knockout of microRNA-21 reduces biliary hyperplasia and liver fibrosis in cholestatic bile duct ligated mice

(2016) Lindsey L Kennedy et al.   LABORATORY INVESTIGATION

Arsenic Exposure and Predicted 10-Year Atherosclerotic Cardiovascular Risk Using the Pooled Cohort Equations in U.S. Hypertensive Adults

(2016) Qingjiao Nong et al.   International Journal of Environmental Research and Public Health

Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis

(2015) Diptadip Dattaroy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The health effects of exposure to arsenic-contaminated drinking water: a review by global geographical distribution

(2014) Lei Huang et al.   INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH

Exposure of hepatocellular carcinoma cells to low-level As2O3‎ causes an extra toxicity pathway via L1 retrotransposition ‎induction

(2014) Abbas Karimi et al.   TOXICOLOGY LETTERS

Blockage of a miR-21/EGFR regulatory feedback loop augments anti-EGFR therapy in glioblastomas

(2013) Kai-liang Zhang et al.   CANCER LETTERS

The Broad Scope of Health Effects from Chronic Arsenic Exposure: Update on a Worldwide Public Health Problem

(2013) Marisa F. Naujokas et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells

(2011) Erica Novo et al.   JOURNAL OF PATHOLOGY

Acetaminophen hepatotoxicity and HIF-1α induction in acetaminophen toxicity in mice occurs without hypoxia

(2011) Shubhra Chaudhuri et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Comparison of drinking water, raw rice and cooking of rice as arsenic exposure routes in three contrasting areas of West Bengal, India

(2010) Debapriya Mondal et al.   ENVIRONMENTAL GEOCHEMISTRY AND HEALTH

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

(2010) Gang Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Intrahepatic angiogenesis and sinusoidal remodeling in chronic liver disease: New targets for the treatment of portal hypertension?

(2010) Dominique Thabut et al.   JOURNAL OF HEPATOLOGY

Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia-inducible factor and transforming growth factor-β-dependent mechanisms

(2010) Bryan L. Copple   LIVER INTERNATIONAL

Oxidative stress and hepatic stellate cell activation are key events in arsenic induced liver fibrosis in mice

(2010) Subhadip Ghatak et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Reduced liver fibrosis in hypoxia-inducible factor-1α-deficient mice

(2009) Jeon-OK Moon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

HIF-1: upstream and downstream of cancer metabolism

(2009) Gregg L Semenza   CURRENT OPINION IN GENETICS & DEVELOPMENT

Hypoxia-inducible factor-dependent production of profibrotic mediators by hypoxic hepatocytes

(2009) Bryan L. Copple et al.   LIVER INTERNATIONAL

Toxicogenomics of arsenic: Classical ideas and recent advances

(2008) P GHOSH et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE