lncRNA OTUD6B-AS1 Exacerbates As2O3-Induced Oxidative Damage in Bladder Cancer via miR-6734-5p-Mediated Functional Inhibition of IDH2

Long non-coding RNA ROR confers arsenic trioxide resistance to HepG2 cells by inhibiting p53 expression

(2020) Xinyang Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

MitoQ Modulates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction via Regulating Nrf2 Signaling

(2020) Shengfeng Zhang et al.   MEDIATORS OF INFLAMMATION

Long-term arsenite exposure decreases autophagy by increased release of Nrf2 in transformed human keratinocytes

(2020) Jing Wu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Novel long noncoding RNA OTUD6B-AS1 indicates poor prognosis and inhibits clear cell renal cell carcinoma proliferation via the Wnt/β-catenin signaling pathway

(2019) Gang Wang et al.   Molecular Cancer

IDH2 deficiency exacerbates acetaminophen hepatotoxicity in mice via mitochondrial dysfunction-induced apoptosis

(2019) Hyunjin Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Arsenic trioxide inhibits EMT in hepatocellular carcinoma by promoting lncRNA MEG3 via PKM2

(2019) Zhuoyang Fan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Qianggan extract improved nonalcoholic steatohepatitis by modulating lncRNA/circRNA immune ceRNA networks

(2019) Mingzhe Zhu et al.   BMC Complementary and Alternative Medicine

Reactive oxygen species-mediated senescence is accelerated by inhibiting Cdk2 in Idh2-deficient conditions

(2019) Unbin Chae et al.   Aging-US

The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress

(2019) Laura Moreno Leon et al.   ONCOGENE

BML-111 alleviates acute lung injury through regulating the expression of lncRNA MALAT1

(2018) Hongbin Li et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Hydrogen sulfide upregulated lncRNA CasC7 to reduce neuronal cell apoptosis in spinal cord ischemia-reperfusion injury rat

(2018) Yang Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer

(2018) Zehua Wang et al.   CANCER CELL

Catalase down-regulation in cancer cells exposed to arsenic trioxide is involved in their increased sensitivity to a pro-oxidant treatment

(2018) Christophe Glorieux et al.   Cancer Cell International

LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress

(2018) Ming Gao et al.   TOXICOLOGY LETTERS

LncRNA MT1DP Aggravates Cadmium-Induced Oxidative Stress by Repressing the Function of Nrf2 and is Dependent on Interaction with miR-365

(2018) Ming Gao et al.   Advanced Science

Arsenic induces autophagy in developmental mouse cerebral cortex and hippocampus by inhibiting PI3K/Akt/mTOR signaling pathway: involvement of blood–brain barrier’s tight junction proteins

(2018) Ram Kumar Manthari et al.   ARCHIVES OF TOXICOLOGY

Additive antitumor effect of arsenic trioxide combined with intravesical bacillus Calmette–Guerin immunotherapy against bladder cancer through blockade of the IER3/Nrf2 pathway

(2018) Ming-Huan Mao et al.   BIOMEDICINE & PHARMACOTHERAPY

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

LNMAT1 promotes lymphatic metastasis of bladder cancer via CCL2 dependent macrophage recruitment

(2018) Changhao Chen et al.   Nature Communications

Morphine Postconditioning alleviates autophage in ischemia-reperfusion induced cardiac injury through up-regulating lncRNA UCA1

(2018) Zuolei Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

A Novel Angiotensin II–Induced Long Noncoding RNA Giver Regulates Oxidative Stress, Inflammation, and Proliferation in Vascular Smooth Muscle Cells

(2018) Sadhan Das et al.   CIRCULATION RESEARCH

Bladder Preservation With Twice-a-Day Radiation Plus Fluorouracil/Cisplatin or Once Daily Radiation Plus Gemcitabine for Muscle-Invasive Bladder Cancer: NRG/RTOG 0712—A Randomized Phase II Trial

(2018) John J. Coen et al.   JOURNAL OF CLINICAL ONCOLOGY

Depletion of Ars2 inhibits cell proliferation and leukemogenesis in acute myeloid leukemia by modulating the miR-6734-3p/p27 axis

(2018) Xiaoye Hu et al.   LEUKEMIA

Bladder Cancer Incidence and Mortality: A Global Overview and Recent Trends

(2017) Sebastien Antoni et al.   EUROPEAN UROLOGY

STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4

(2017) Hui Wang et al.   Molecular Cancer

Idh2 Deficiency Exacerbates Acrolein-Induced Lung Injury through Mitochondrial Redox Environment Deterioration

(2017) Jung Hyun Park et al.   Oxidative Medicine and Cellular Longevity

TGFβ1 Promotes Gemcitabine Resistance through Regulating the LncRNA-LET/NF90/miR-145 Signaling Axis in Bladder Cancer

(2017) Junlong Zhuang et al.   Theranostics

Bladder cancer

(2017) Oner Sanli et al.   Nature Reviews Disease Primers

Randomized controlled study of the efficacy and safety of continuous saline bladder irrigation after transurethral resection for the treatment of non-muscle-invasive bladder cancer

(2016) Takehisa Onishi et al.   BJU INTERNATIONAL

Long-term outcome of acute promyelocytic leukemia treated with all- trans -retinoic acid, arsenic trioxide, and gemtuzumab

(2016) Yasmin Abaza et al.   BLOOD

ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction underlie apoptosis induced by resveratrol and arsenic trioxide in A549 cells

(2016) Shiyan Gu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner

(2016) Wen-Tao Wang et al.   Journal of Hematology & Oncology

Bladder cancer

(2016) Ashish M Kamat et al.   LANCET

miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells

(2016) Moo Rim Kang et al.   PLoS One

Metal responsive transcription factor 1 (MTF-1) regulates zinc dependent cellular processes at the molecular level

(2015) Agata Grzywacz et al.   ACTA BIOCHIMICA POLONICA

Genetic variation in metallothionein and metal-regulatory transcription factor 1 in relation to urinary cadmium, copper, and zinc

(2015) Scott V. Adams et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Zinc regulates a key transcriptional pathway for epileptogenesis via metal-regulatory transcription factor 1

(2015) Karen M. J. van Loo et al.   Nature Communications

Resveratrol Synergistically Triggers Apoptotic Cell Death with Arsenic Trioxide via Oxidative Stress in Human Lung Adenocarcinoma A549 Cells

(2014) Shiyan Gu et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Arsenic trioxide transarterial chemoembolization with and without additional intravenous administration of arsenic trioxide in unresectable hepatocellular carcinoma with lung metastasis: a single-blind, randomized trial

(2014) Bing Liu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Cadmium in blood of Tunisian men and risk of bladder cancer: interactions with arsenic exposure and smoking

(2013) Molka Feki-Tounsi et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Arsenic Trioxide (ATO) Influences the Gene Expression of Metallothioneins in Human Glioblastoma Cells

(2012) Ingrid Falnoga et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Arsenic Trioxide in Recurrent Urothelial Cancer: A Cancer and Leukemia Group B Phase II Trial (CALGB 99903)

(2009) Dean F. Bajorin et al.   Clinical Genitourinary Cancer

Induction of Metallothionein I by Arsenic via Metal-activated Transcription Factor 1

(2009) Xiaoqing He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arsenic Trioxide in Patients With Adenocarcinoma of the Pancreas Refractory to Gemcitabine

(2008) Hedy Lee Kindler et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS