State of the art in microRNA as diagnostic and therapeutic biomarkers in chronic lymphocytic leukemia

Expression of circulating miRNAs associated with lymphocyte differentiation and activation in CLL—another piece in the puzzle

(2016) Agata A. Filip et al.   ANNALS OF HEMATOLOGY

Extracellular vesicles released by CD40/IL-4-stimulated CLL cells confer altered functional properties to CD4+ T cells

(2016) D. T. Smallwood et al.   BLOOD

Imaging techniques: new avenues in cancer gene and cell therapy

(2016) Z Saadatpour et al.   CANCER GENE THERAPY

Molecular imaging and cancer gene therapy

(2016) Z Saadatpour et al.   CANCER GENE THERAPY

Circulating microRNA-192 as a diagnostic biomarker in human chronic lymphocytic leukemia

(2016) S Fathullahzadeh et al.   CANCER GENE THERAPY

Circulating microRNA: a new candidate for diagnostic biomarker in neuroblastoma

(2016) M Mohammadi et al.   CANCER GENE THERAPY

Glioblastoma: exosome and microRNA as novel diagnosis biomarkers

(2016) L Saadatpour et al.   CANCER GENE THERAPY

Role of microRNAs in regulation of the TNF/TNFR gene superfamily in chronic lymphocytic leukemia

(2016) Swati Srivastava et al.   CLINICAL BIOCHEMISTRY

Epi-Drugs and Epi-miRs: Moving Beyond Current Cancer Therapies

(2016) Reza Salarinia et al.   CURRENT CANCER DRUG TARGETS

Circulating microRNAs as Potential Diagnostic Biomarkers and Therapeutic Targets in Gastric Cancer: Current Status and Future Perspectives

(2016) Hamed Mirzaei et al.   CURRENT MEDICINAL CHEMISTRY

Circulating microRNAs in Hepatocellular Carcinoma: Potential Diagnostic and Prognostic Biomarkers

(2016) Hamid Mirzaei et al.   CURRENT PHARMACEUTICAL DESIGN

MicroRNAs as potential diagnostic and prognostic biomarkers in melanoma

(2016) Hamed Mirzaei et al.   EUROPEAN JOURNAL OF CANCER

Biological analysis of chronic lymphocytic leukemia: integration of mRNA and microRNA expression profiles

(2016) L. Dong et al.   GENETICS AND MOLECULAR RESEARCH

Curcumin: A new candidate for melanoma therapy?

(2016) Hamed Mirzaei et al.   INTERNATIONAL JOURNAL OF CANCER

Ibrutinib downregulates a subset of miRNA leading to upregulation of tumor suppressors and inhibition of cell proliferation in chronic lymphocytic leukemia

(2016) L M Saleh et al.   LEUKEMIA

Dissecting chronic lymphocytic leukemia with 13q- using microRNA expression profile

(2016) Pellegrino Musto et al.   LEUKEMIA RESEARCH

Genetic profiling of CLL: a ‘TP53 addict’ perspective

(2016) L Lodé et al.   Cell Death & Disease

Prognostic Factors for Chronic Lymphocytic Leukemia

(2016) Christopher Chen et al.   Current Hematologic Malignancy Reports

Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts

(2015) J. Paggetti et al.   BLOOD

miRs-138 and -424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in CLL

(2015) V. Berg et al.   BLOOD

Characterization of CLL exosomes reveals a distinct microRNA signature and enhanced secretion by activation of BCR signaling

(2015) Y.-Y. Yeh et al.   BLOOD

The potential for circulating microRNAs in the diagnosis of myocardial infarction: a novel approach to disease diagnosis and treatment

(2015) Sharareh Gholamin et al.   CURRENT PHARMACEUTICAL DESIGN

Increased chronic lymphocytic leukemia proliferation upon IgM stimulation is sustained by the upregulation of miR-132 and miR-212

(2015) Simona Tavolaro et al.   GENES CHROMOSOMES & CANCER

Role of microRNA in chronic lymphocytic leukemia onset and progression

(2015) Veronica Balatti et al.   Journal of Hematology & Oncology

Diagnostic and prognostic role of PET/CT in patients with chronic lymphocytic leukemia and progressive disease

(2015) F R Mauro et al.   LEUKEMIA

miR-377-dependent BCL-xL regulation drives chemotherapeutic resistance in B-cell lymphoid malignancies

(2015) Sayer Al-harbi et al.   Molecular Cancer

CLL Exosomes Modulate the Transcriptome and Behaviour of Recipient Stromal Cells and Are Selectively Enriched in miR-202-3p

(2015) Mosavar Farahani et al.   PLoS One

TCL1targetingmiR-3676is codeleted with tumor protein p53 in chronic lymphocytic leukemia

(2015) Veronica Balatti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor Growth

(2015) Kazuyoshi Shiga et al.   Cancers

MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia

(2014) B. Cui et al.   BLOOD

Prognostic and Predictive Factors in Patients With Chronic Lymphocytic Leukemia: Relevant in the Era of Novel Treatment Approaches?

(2014) Daniel Mertens et al.   JOURNAL OF CLINICAL ONCOLOGY

Genomic aberrations deletion 11q and deletion 17p independently predict for worse progression-free and overall survival after allogeneic hematopoietic cell transplantation for chronic lymphocytic leukemia

(2014) Julio C. Chavez et al.   LEUKEMIA RESEARCH

mmu-miR-702 functions as an anti-apoptotic mirtron by mediating ATF6 inhibition in mice

(2013) Wei-guang Zhang et al.   GENE

Biology of Chronic Lymphocytic Leukemia in Different Microenvironments

(2013) Yair Herishanu et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

MicroRNAs and B cell receptor signaling in chronic lymphocytic leukemia

(2013) Marek Mraz et al.   LEUKEMIA & LYMPHOMA

Epigenetic inactivation of miR-9 family microRNAs in chronic lymphocytic leukemia - implications on constitutive activation of NFκB pathway

(2013) Lu Wang et al.   Molecular Cancer

B-cell malignancies in microRNA E -miR-17 92 transgenic mice

(2013) S. K. Sandhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

B cell receptor signaling in chronic lymphocytic leukemia

(2013) Jan A. Burger et al.   TRENDS IN IMMUNOLOGY

“Role of the B-cell receptor and the microenvironment in chronic lymphocytic leukemia’’

(2013) P Oppezzo et al.   Blood Cancer Journal

FISH Analysis for del6q21 and del17p13 in B-cell Chronic Lymphocytic Leukemia in Iranians

(2013) Hossein Teimori et al.   Iranian Red Crescent Medical Journal

The B-cell receptor signaling pathway as a therapeutic target in CLL

(2012) J. A. Woyach et al.   BLOOD

Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy

(2012) M. A. Swartz et al.   CANCER RESEARCH

miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes

(2012) Dan-Xia Zhu et al.   CARCINOGENESIS

Targeting Bcl-2 in CLL

(2012) M. Rogalinska et al.   CURRENT MEDICINAL CHEMISTRY

MicroRNAs in B cell development and malignancy

(2012) Thilini R Fernando et al.   Journal of Hematology & Oncology

The miR-17∼92 family regulates the response to Toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes

(2012) R Bomben et al.   LEUKEMIA

MicroRNA and cancer

(2012) Martin D. Jansson et al.   Molecular Oncology

Cancer biomarkers: selecting the right drug for the right patient

(2012) Gary J. Kelloff et al.   NATURE REVIEWS DRUG DISCOVERY

Molecular Characterization of Chronic Lymphocytic Leukemia Patients with a High Number of Losses in 13q14

(2012) Ana Eugenia Rodríguez et al.   PLoS One

Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL)

(2012) A. Palamarchuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acquired genomic copy number aberrations and survival in chronic lymphocytic leukemia

(2011) P. Ouillette et al.   BLOOD

Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia

(2011) D. Rossi et al.   BLOOD

miR-181b is a biomarker of disease progression in chronic lymphocytic leukemia

(2011) R. Visone et al.   BLOOD

Stromal cells and CD40 ligand (CD154) alter the miRNome and induce miRNA clusters including, miR-125b/miR-99a/let-7c and miR-17-92 in chronic lymphocytic leukaemia

(2011) S Willimott et al.   LEUKEMIA

MicroRNAs in Development and Disease

(2011) Danish Sayed et al.   PHYSIOLOGICAL REVIEWS

MicroRNA Expression Profiling Identifies Activated B Cell Status in Chronic Lymphocytic Leukemia Cells

(2011) Shuqiang Li et al.   PLoS One

MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia

(2011) E. Moussay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High Serum Thymidine Kinase 1 Level Predicts Poorer Survival in Patients With Chronic Lymphocytic Leukemia

(2010) Sergej N. Konoplev et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Limited clinical relevance of imaging techniques in the follow-up of patients with advanced chronic lymphocytic leukemia: results of a meta-analysis

(2010) B. F. Eichhorst et al.   BLOOD

Targeting kinases in CML CLL

(2010) V. Gandhi   BLOOD

microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival

(2010) S. Rossi et al.   BLOOD

Elevations of tumor necrosis factor receptor 1 at day 7 and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation with nonmyeloablative conditioning

(2010) E Willems et al.   BONE MARROW TRANSPLANTATION

A transcriptome-wide approach reveals the key contribution of NFI-A in promoting erythroid differentiation of human CD34+ progenitors and CML cells

(2010) L M Starnes et al.   LEUKEMIA

Karyotype-specific microRNA signature in chronic lymphocytic leukemia

(2009) R. Visone et al.   BLOOD

Monoallelic and biallelic inactivation of TP53 gene in chronic lymphocytic leukemia: selection, impact on survival, and response to DNA damage

(2009) J. Malcikova et al.   BLOOD

Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells

(2009) A. K. Ghosh et al.   BLOOD

miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia

(2009) C. P. Pallasch et al.   BLOOD

F18-fluorodeoxyglucose positron emission tomography in the context of other imaging techniques and prognostic factors in multiple myeloma

(2009) T. B. Bartel et al.   BLOOD

International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple Myeloma

(2009) M Dimopoulos et al.   LEUKEMIA

MicroRNAs in chronic lymphocytic leukemia pathogenesis and disease subtypes

(2009) Marek Mraz et al.   LEUKEMIA & LYMPHOMA

MicroRNA signatures in liver diseases

(2009) Xian-Ming Chen   WORLD JOURNAL OF GASTROENTEROLOGY

Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia

(2008) L. Z. Rassenti et al.   BLOOD

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

(2008) M. Hallek et al.   BLOOD

Prognostic impact of chromosome alterations detected by FISH in Turkish patients with B-cell chronic lymphocytic leukemia

(2008) Beyhan Durak et al.   CANCER GENETICS AND CYTOGENETICS

MicroRNA expression changes during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal, a product of lipid peroxidation

(2008) Stefania Pizzimenti et al.   FREE RADICAL BIOLOGY AND MEDICINE

MicroRNA and cancer - focus on apoptosis

(2008) Yu Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Hedgehog-Induced Survival of B-Cell Chronic Lymphocytic Leukemia Cells in a Stromal Cell Microenvironment: A Potential New Therapeutic Target

(2008) G. V. Hegde et al.   MOLECULAR CANCER RESEARCH

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

(2008) Changchun Xiao et al.   NATURE IMMUNOLOGY

MiR-15a and miR-16-1 cluster functions in human leukemia

(2008) George A. Calin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA